H. Kaizuka, K. Sugimoto, M. Abe, Yu Yoshimasu, Hirohito Takeuchi, Yoshitaka Kasai, N. Shirota, T. Saguchi, H. Yamaguchi, T. Itoi
{"title":"Successful management of a congenital portosystemic shunt using coil-in-plug embolization: A case report","authors":"H. Kaizuka, K. Sugimoto, M. Abe, Yu Yoshimasu, Hirohito Takeuchi, Yoshitaka Kasai, N. Shirota, T. Saguchi, H. Yamaguchi, T. Itoi","doi":"10.2957/kanzo.63.232","DOIUrl":"https://doi.org/10.2957/kanzo.63.232","url":null,"abstract":"A 20-year-old man was referred to pediatrics for hyperbilirubinemia and mental retardation. Abdominal ultrasonography findings were indicative of a portosystemic shunt, and as a shunt between the left branch of the portal vein and inferior vena cava was confirmed by abdominal computed tomography, he was diagnosed with patency of the venous duct. We decided to perform shunt embolization using IVR, but as the shunt diame-ter had expanded like a funnel, its embolization was performed using a plug-and -metal coil, which led to an im-provement in hepatic reserve and blood ammonia levels postprocedure. Surgical ligation has been typically used in the management of portosystemic shunts, but as it is highly invasive, shunt embolization by IVR has become prevalent in recent years. Here we describe stable embolization using the IVR technique.","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48838909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hikari Kobayashi, H. Nagai, T. Mukozu, Kunihide Mori, Gou Watanabe, Naoyuki Yoshimine, Kojiro Kobayashi, Y. Ogino, Teppei Matsui, Yasuko Daido, N. Wakui, Koichi Momiyama, Y. Igarashi
{"title":"A case of drug-induced liver injury causing cirrhosis in the short term by the treatment of amiodarone","authors":"Hikari Kobayashi, H. Nagai, T. Mukozu, Kunihide Mori, Gou Watanabe, Naoyuki Yoshimine, Kojiro Kobayashi, Y. Ogino, Teppei Matsui, Yasuko Daido, N. Wakui, Koichi Momiyama, Y. Igarashi","doi":"10.2957/kanzo.63.203","DOIUrl":"https://doi.org/10.2957/kanzo.63.203","url":null,"abstract":"The patient was a man in his 70s who had been attending our hospitalʼs Department of Cardiology for an old myocardial infarction; however, in 20XX, a defibrillator was implanted due to cardiac arrest caused by ven-tricular fibrillation, and amiodarone was used to prevent arrhythmia. He was referred to our department 1 year and 8 months after taking amiodarone due to liver damage, and an abdominal simple CT examination showed high absorption of the liver. He was diagnosed with drug-induced liver injury due to amiodarone and was ad-vised to discontinue the drug; however, the drug administration was continued because there was no alterna-tive drug. He was diagnosed with cirrhosis four years and one month after starting amiodarone, and he stopped taking it. He died of liver failure six months later. Because amiodarone-induced drug-induced liver injury can quickly progress to cirrhosis, it is important to monitor blood levels of amiodarone and adjust the dose.","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41846744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuma Aoki, A. Kinoshita, Akiyuki Osawa, T. Kano, Yuko Sato, Yuki Mitsuyoshi, K. Koike, M. Saruta
{"title":"A case of an elderly patient with chronic hepatitis C exacerbated by chemotherapy for malignant lymphoma and improved by direct-acting antivirals therapy","authors":"Yuma Aoki, A. Kinoshita, Akiyuki Osawa, T. Kano, Yuko Sato, Yuki Mitsuyoshi, K. Koike, M. Saruta","doi":"10.2957/kanzo.63.196","DOIUrl":"https://doi.org/10.2957/kanzo.63.196","url":null,"abstract":"","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42843481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liver biopsy implementation rate for diagnosis of NASH in Japan -analysis of big data of health insurance claims-","authors":"Aya Sugiyama, Akemi Kurisu, T. Kumada, J. Tanaka","doi":"10.2957/kanzo.63.211","DOIUrl":"https://doi.org/10.2957/kanzo.63.211","url":null,"abstract":"","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47148852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toshimitsu Yasui, Yujiro Adachi, Shin Satake, Kenji Aoi, Hisashi Jou, Naruyasu Kakita, Y. Yamada, T. Tabuchi, K. Katayama
{"title":"Examination of factors contributing to the prognosis in TACE treatment of hepatocellular carcinoma","authors":"Toshimitsu Yasui, Yujiro Adachi, Shin Satake, Kenji Aoi, Hisashi Jou, Naruyasu Kakita, Y. Yamada, T. Tabuchi, K. Katayama","doi":"10.2957/kanzo.63.187","DOIUrl":"https://doi.org/10.2957/kanzo.63.187","url":null,"abstract":"","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46728807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hitoshi Nishio, Yuichi Honma, Keiichiro Kumamoto, Y. Toki, Kahori Morino, Shinji Oe, Koichiro Miyagawa, Michihiko Shibata, S. Abe, Y. Tatsumi, K. Ikuta, H. Hayashi, M. Harada
{"title":"A case of hemochromatosis due to heterozygous mutations in TfR2","authors":"Hitoshi Nishio, Yuichi Honma, Keiichiro Kumamoto, Y. Toki, Kahori Morino, Shinji Oe, Koichiro Miyagawa, Michihiko Shibata, S. Abe, Y. Tatsumi, K. Ikuta, H. Hayashi, M. Harada","doi":"10.2957/kanzo.63.151","DOIUrl":"https://doi.org/10.2957/kanzo.63.151","url":null,"abstract":"","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47790985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tsunamasa Watanabe, Po-sung Chu, T. Ehira, Y. Hasegawa, N. Hattori, M. Shinoda, H. Ikeda, Hanako Tsujikawa, H. Obara, Masaki Hara, Tatsuya Suzuki, K. Matsunaga, C. Okuse, F. Itoh
{"title":"Dynamic contrast-enhanced CT at the early stage confirms two cases of acute liver failure due to acute-onset autoimmune hepatitis with extensive liver necrosis","authors":"Tsunamasa Watanabe, Po-sung Chu, T. Ehira, Y. Hasegawa, N. Hattori, M. Shinoda, H. Ikeda, Hanako Tsujikawa, H. Obara, Masaki Hara, Tatsuya Suzuki, K. Matsunaga, C. Okuse, F. Itoh","doi":"10.2957/kanzo.63.158","DOIUrl":"https://doi.org/10.2957/kanzo.63.158","url":null,"abstract":"[Case 1] A 54-year-old female presented with severe liver damage. During diagnosis, contrast-enhanced CT enhanced the area of hypoattenuation on unenhanced CT in the arterial phase, after which the enhanced effect was prolonged to the equilibrium phase. Then, we started immunosuppressive therapy based on the results, including corticosteroid administration, and her hepatitis subsided. [Case 2] A 57-year-old female also presented with severe hepatitis. Contrast-enhanced CT findings were similar to those of Case 1. Since hepatic encephalo-pathy developed and worsened to degree IV, a brain-dead liver transplant was conducted on the 21st day. Nev-ertheless, histological diagnosis was challenging in both cases. Therefore, when unenhanced CT shows hetero-geneous hypoattenuation in the liver and contrast-enhanced CT shows a characteristic blood flow disorder, acute-onset autoimmune hepatitis and corticosteroid treatment should be considered, including in complex se-rological or histological case diagnoses.","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48248212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takeshi Matsui, Kazunari Tanaka, R. Minami, K. Tsuji, Jong‐Hon Kang, A. Katanuma, Shinsuke Onishi
{"title":"A pre-existing case of HBV infection with elevated HBV DNA after COVID-19 pneumonia treatment","authors":"Takeshi Matsui, Kazunari Tanaka, R. Minami, K. Tsuji, Jong‐Hon Kang, A. Katanuma, Shinsuke Onishi","doi":"10.2957/kanzo.63.170","DOIUrl":"https://doi.org/10.2957/kanzo.63.170","url":null,"abstract":"The patient presented with fever and appetite loss. Computed tomography (CT) revealed a moderate grade 2 pneumonia. Besides, further blood examination showed his HB antigen as negative, anti-HBs/c anti-body as positive, and HBV DNA level as 1.0 LIU/mL. Therefore, he was diagnosed with COVID-19. Administered treatments comprised oxygen inhalation and steroid therapy, including pulses, remdesivir, and baricitinib, which improved pneumonia. Interestingly, one month posttreatment, his HBV DNA level in-creased to 1.4 LIU/mL, followed by a further increase to 1.7 LIU/Ml, showing an improvement. Tenofovir alafenamide fumarate was thus administered. In clinical practice, immunosuppressive therapy is used for patients with moderate-to-severe COVID-19 pneumo-nia. However, close attention should also be paid to the elevation of blood HBV DNA levels during and after treatment.","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47159587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomoko Tadokoro, J. Tani, Kei Takuma, Mai Nakahara, K. Oura, Koji Fujita, Shima Mimura, M. Ono, A. Morishita, Tsutomu Masaki
{"title":"Clinical features of hepatic dysfunction caused by immune checkpoint inhibitors and treatment of refractory cases","authors":"Tomoko Tadokoro, J. Tani, Kei Takuma, Mai Nakahara, K. Oura, Koji Fujita, Shima Mimura, M. Ono, A. Morishita, Tsutomu Masaki","doi":"10.2957/kanzo.63.107","DOIUrl":"https://doi.org/10.2957/kanzo.63.107","url":null,"abstract":"","PeriodicalId":35810,"journal":{"name":"Acta Hepatologica Japonica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45391853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}