Wei-Qing Song , Xu Zheng , Hai-Ni Li , Li Li , Jiang-Shui Yuan , Shu-Guo Wang
{"title":"“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis: A Case Report","authors":"Wei-Qing Song , Xu Zheng , Hai-Ni Li , Li Li , Jiang-Shui Yuan , Shu-Guo Wang","doi":"10.24920/004152","DOIUrl":"10.24920/004152","url":null,"abstract":"<div><p>We report a case of hemophagocytic syndrome (HPS) secondary to brucellosis, in which typhoidal cells were found in bone marrow, suggesting typhoidal cells present not only in <em>Salmonella typhi</em> infections but also in other bacterial infections. Typhoidal cells in bone marrow can be used to quickly identify the presence of bacterial infection pending the results of bone marrow and/or blood cultures.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 62-65"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9313207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in Medical Treatment of Primary Aldosteronism","authors":"Ying-Jie Li, Zhi-Gang Ji, Jin Wen","doi":"10.24920/004137","DOIUrl":"10.24920/004137","url":null,"abstract":"<div><p>Primary aldosteronism (PA) is the most common form of secondary hypertension, with its main manifestations including hypertension and hypokalemia. Early identification of PA is extremely important as PA patients can easily develop cardiovascular complications such as atrial fibrillation, stroke, and myocardial infarction. The past decade has witnessed the rapid advances in the genetics of PA, which has shed new light on PA treatment. While surgery is the first choice for unilateral diseases, bilateral lesions can be treated with mineralocorticoid receptor antagonists (MRAs). The next-generation non-steroidal MRAs are under investigations. New medications including calcium channel blockers, macrophage antibiotics, and aldosterone synthase inhibitors have provided a new perspective for the medical treatment of PA.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 49-56"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9320727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaveh Shahveisi , Seyedeh Marziyeh Hadi , Hamed Ghazvini , Mehdi Khodamoradi
{"title":"Role of Cannabinoid CB1, Receptor in Object Recognition Memory Impairment in Chronically Rapid Eye Movement Sleep-deprived Rats","authors":"Kaveh Shahveisi , Seyedeh Marziyeh Hadi , Hamed Ghazvini , Mehdi Khodamoradi","doi":"10.24920/004087","DOIUrl":"https://doi.org/10.24920/004087","url":null,"abstract":"<div><h3>Objective</h3><p>We aimed to investigate whether antagonism of the cannabinoid CB<sub>1</sub> receptor (CB<sub>1</sub>R) could affect novel object recognition (NOR) memory in chronically rapid eye movement sleep-deprived (RSD) rats.</p></div><div><h3>Methods</h3><p>The animals were examined for recognition memory following a 7-day chronic partial RSD paradigm using the multiple platform technique. The CB<sub>1</sub>R antagonist rimonabant (1 or 3 mg/kg, i.p.) was administered either at one hour prior to the sample phase for acquisition, or immediately after the sample phase for consolidation, or at one hour before the test phase for retrieval of NOR memory. For the reconsolidation task, rimonabant was administered immediately after the second sample phase.</p></div><div><h3>Results</h3><p>The RSD episode impaired acquisition, consolidation, and retrieval, but it did not affect the reconsolidation of NOR memory. Rimonabant administration did not affect acquisition, consolidation, and reconsolidation; however, it attenuated impairment of the retrieval of NOR memory induced by chronic RSD.</p></div><div><h3>Conclusions</h3><p>These findings, along with our previous report, would seem to suggest that RSD may affect different phases of recognition memory based on its duration. Importantly, it seems that the CB<sub>1</sub>R may, at least in part, be involved in the adverse effects of chronic RSD on the retrieval, but not in the acquisition, consolidation, and reconsolidation, of NOR memory.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 29-37"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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