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Intelligent Electrocardiogram Analysis in Medicine: Data, Methods, and Applications 医学中的智能心电图分析：数据、方法和应用
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004160
Yu-Xia Guan , Ying An , Feng-Yi Guo , Wei-Bai Pan , Jian-Xin Wang
{"title":"Intelligent Electrocardiogram Analysis in Medicine: Data, Methods, and Applications","authors":"Yu-Xia Guan ,&nbsp;Ying An ,&nbsp;Feng-Yi Guo ,&nbsp;Wei-Bai Pan ,&nbsp;Jian-Xin Wang","doi":"10.24920/004160","DOIUrl":"10.24920/004160","url":null,"abstract":"<div><p>Electrocardiogram (ECG) is a low-cost, simple, fast, and non-invasive test. It can reflect the heart's electrical activity and provide valuable diagnostic clues about the health of the entire body. Therefore, ECG has been widely used in various biomedical applications such as arrhythmia detection, disease-specific detection, mortality prediction, and biometric recognition. In recent years, ECG-related studies have been carried out using a variety of publicly available datasets, with many differences in the datasets used, data preprocessing methods, targeted challenges, and modeling and analysis techniques. Here we systematically summarize and analyze the ECG-based automatic analysis methods and applications. Specifically, we first reviewed 22 commonly used ECG public datasets and provided an overview of data preprocessing processes. Then we described some of the most widely used applications of ECG signals and analyzed the advanced methods involved in these applications. Finally, we elucidated some of the challenges in ECG analysis and provided suggestions for further research.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 38-48"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9314183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blue Nevus Hidden within the Nevus of Ota 藏在太田痣中的蓝色痣
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004092
Xing Liu , Hui-Ying Zheng , Fu-Min Fang , He-Dan Yang , Hui Ding , Yin Yang , Yi-Ping Ge , Tong Lin
{"title":"Blue Nevus Hidden within the Nevus of Ota","authors":"Xing Liu ,&nbsp;Hui-Ying Zheng ,&nbsp;Fu-Min Fang ,&nbsp;He-Dan Yang ,&nbsp;Hui Ding ,&nbsp;Yin Yang ,&nbsp;Yi-Ping Ge ,&nbsp;Tong Lin","doi":"10.24920/004092","DOIUrl":"10.24920/004092","url":null,"abstract":"<div><p>A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face. After several sessions of laser treatment, the azury patch in the periorbital area became even darker. Histopathology showed many bipolar, pigment-laden dendritic cells scattered in the papillary and upper reticular dermis. Immunohistochemically, these cells were positive for S100, SOX-10, melan-A, P16, and HMB-45. The positive rate of Ki-67 was less than 5%. Finally, the lesion was diagnosed with nevus of Ota concurrent with common blue nevus. Therefore, for cases of the nevus of Ota with poor response to laser treatment, the possible coexisting diseases should be suspected.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 70-72"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9313720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report ANCA和抗GBM抗体双阳性患者组织性肺炎一例报告
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004161
Fang-Yuan Wang , Xiang-Ning Yuan , Dan-Ni Sun , Gong Xiao , Cheng-Huan Hu , Zhong-Hua Liao , Jian-Ping Ning , Hui Xu , Jun-Tao Feng , Hong-Ling Yin , Xiao-Zhao Li
{"title":"Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report","authors":"Fang-Yuan Wang ,&nbsp;Xiang-Ning Yuan ,&nbsp;Dan-Ni Sun ,&nbsp;Gong Xiao ,&nbsp;Cheng-Huan Hu ,&nbsp;Zhong-Hua Liao ,&nbsp;Jian-Ping Ning ,&nbsp;Hui Xu ,&nbsp;Jun-Tao Feng ,&nbsp;Hong-Ling Yin ,&nbsp;Xiao-Zhao Li","doi":"10.24920/004161","DOIUrl":"10.24920/004161","url":null,"abstract":"<div><p>Both anti-glomerular basement membrane (GBM) disease and the anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are common causes of pulmonary-renal syndrome. Organizing pneumonia (OP), a special pattern of interstitial lung disease, is extremely rare either in AAV or anti-GBM disease. We report an old woman presented with OP on a background of co-presentation with both ANCA and anti-GBM antibodies.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 66-69"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9320180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis: A Case Report “伤寒细胞”出现在一例布鲁氏菌病继发性吞噬细胞综合征妇女身上
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004152
Wei-Qing Song , Xu Zheng , Hai-Ni Li , Li Li , Jiang-Shui Yuan , Shu-Guo Wang
{"title":"“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis: A Case Report","authors":"Wei-Qing Song ,&nbsp;Xu Zheng ,&nbsp;Hai-Ni Li ,&nbsp;Li Li ,&nbsp;Jiang-Shui Yuan ,&nbsp;Shu-Guo Wang","doi":"10.24920/004152","DOIUrl":"10.24920/004152","url":null,"abstract":"<div><p>We report a case of hemophagocytic syndrome (HPS) secondary to brucellosis, in which typhoidal cells were found in bone marrow, suggesting typhoidal cells present not only in <em>Salmonella typhi</em> infections but also in other bacterial infections. Typhoidal cells in bone marrow can be used to quickly identify the presence of bacterial infection pending the results of bone marrow and/or blood cultures.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 62-65"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9313207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in Medical Treatment of Primary Aldosteronism 原发性醛固酮增多症的医学治疗进展
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004137
Ying-Jie Li, Zhi-Gang Ji, Jin Wen
{"title":"Advances in Medical Treatment of Primary Aldosteronism","authors":"Ying-Jie Li,&nbsp;Zhi-Gang Ji,&nbsp;Jin Wen","doi":"10.24920/004137","DOIUrl":"10.24920/004137","url":null,"abstract":"<div><p>Primary aldosteronism (PA) is the most common form of secondary hypertension, with its main manifestations including hypertension and hypokalemia. Early identification of PA is extremely important as PA patients can easily develop cardiovascular complications such as atrial fibrillation, stroke, and myocardial infarction. The past decade has witnessed the rapid advances in the genetics of PA, which has shed new light on PA treatment. While surgery is the first choice for unilateral diseases, bilateral lesions can be treated with mineralocorticoid receptor antagonists (MRAs). The next-generation non-steroidal MRAs are under investigations. New medications including calcium channel blockers, macrophage antibiotics, and aldosterone synthase inhibitors have provided a new perspective for the medical treatment of PA.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 49-56"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9320727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Cannabinoid CB1, Receptor in Object Recognition Memory Impairment in Chronically Rapid Eye Movement Sleep-deprived Rats 大麻酚CB1受体在慢性快速眼动睡眠剥夺大鼠物体识别记忆障碍中的作用
Chinese Medical Sciences Journal Pub Date : 2023-03-01 DOI: 10.24920/004087
Kaveh Shahveisi , Seyedeh Marziyeh Hadi , Hamed Ghazvini , Mehdi Khodamoradi
{"title":"Role of Cannabinoid CB1, Receptor in Object Recognition Memory Impairment in Chronically Rapid Eye Movement Sleep-deprived Rats","authors":"Kaveh Shahveisi ,&nbsp;Seyedeh Marziyeh Hadi ,&nbsp;Hamed Ghazvini ,&nbsp;Mehdi Khodamoradi","doi":"10.24920/004087","DOIUrl":"https://doi.org/10.24920/004087","url":null,"abstract":"<div><h3>Objective</h3><p>We aimed to investigate whether antagonism of the cannabinoid CB<sub>1</sub> receptor (CB<sub>1</sub>R) could affect novel object recognition (NOR) memory in chronically rapid eye movement sleep-deprived (RSD) rats.</p></div><div><h3>Methods</h3><p>The animals were examined for recognition memory following a 7-day chronic partial RSD paradigm using the multiple platform technique. The CB<sub>1</sub>R antagonist rimonabant (1 or 3 mg/kg, i.p.) was administered either at one hour prior to the sample phase for acquisition, or immediately after the sample phase for consolidation, or at one hour before the test phase for retrieval of NOR memory. For the reconsolidation task, rimonabant was administered immediately after the second sample phase.</p></div><div><h3>Results</h3><p>The RSD episode impaired acquisition, consolidation, and retrieval, but it did not affect the reconsolidation of NOR memory. Rimonabant administration did not affect acquisition, consolidation, and reconsolidation; however, it attenuated impairment of the retrieval of NOR memory induced by chronic RSD.</p></div><div><h3>Conclusions</h3><p>These findings, along with our previous report, would seem to suggest that RSD may affect different phases of recognition memory based on its duration. Importantly, it seems that the CB<sub>1</sub>R may, at least in part, be involved in the adverse effects of chronic RSD on the retrieval, but not in the acquisition, consolidation, and reconsolidation, of NOR memory.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"38 1","pages":"Pages 29-37"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50176544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
基于m6A修饰SOCS2调控JAK/STAT通路探讨清热活血方治疗活动期RA临床与机制研究 基于m6A修饰SOCS2调控JAK/STAT通路探讨清热活血方治疗活动期RA临床与机制研究
Chinese Medical Sciences Journal Pub Date : 2023-01-01 DOI: 10.27658/d.cnki.gzzyy.2023.000058
张解玉
{"title":"基于m6A修饰SOCS2调控JAK/STAT通路探讨清热活血方治疗活动期RA临床与机制研究","authors":"张解玉","doi":"10.27658/d.cnki.gzzyy.2023.000058","DOIUrl":"https://doi.org/10.27658/d.cnki.gzzyy.2023.000058","url":null,"abstract":"","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142028033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
益气清解方对IgA肾病小鼠粘膜免疫应答中B淋巴细胞活化与归巢的影响 益气清解方对IgA肾病小鼠粘膜免疫应答中B淋巴细胞活化与归巢的影响
Chinese Medical Sciences Journal Pub Date : 2023-01-01 DOI: 10.27658/d.cnki.gzzyy.2023.000220
吴小聪
{"title":"益气清解方对IgA肾病小鼠粘膜免疫应答中B淋巴细胞活化与归巢的影响","authors":"吴小聪","doi":"10.27658/d.cnki.gzzyy.2023.000220","DOIUrl":"https://doi.org/10.27658/d.cnki.gzzyy.2023.000220","url":null,"abstract":"","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142031013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
粉防己与延胡索毛状根诱导体系及遗传转化体系的建立 粉防己与延胡索毛状根诱导体系及遗传转化体系的建立
Chinese Medical Sciences Journal Pub Date : 2023-01-01 DOI: 10.27658/d.cnki.gzzyy.2023.000191
张秀华
{"title":"粉防己与延胡索毛状根诱导体系及遗传转化体系的建立","authors":"张秀华","doi":"10.27658/d.cnki.gzzyy.2023.000191","DOIUrl":"https://doi.org/10.27658/d.cnki.gzzyy.2023.000191","url":null,"abstract":"","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142031136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
雷公藤红素纳米给药系统设计及光疗-化疗协同抗肿瘤研究 雷公藤红素纳米给药系统设计及光疗-化疗协同抗肿瘤研究
Chinese Medical Sciences Journal Pub Date : 2023-01-01 DOI: 10.27658/d.cnki.gzzyy.2023.000010
陈功森
{"title":"雷公藤红素纳米给药系统设计及光疗-化疗协同抗肿瘤研究","authors":"陈功森","doi":"10.27658/d.cnki.gzzyy.2023.000010","DOIUrl":"https://doi.org/10.27658/d.cnki.gzzyy.2023.000010","url":null,"abstract":"","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142027909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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