Lulu Ma , Xuerong Yu , Xisheng Weng , Jin Lin , Jin Jin , Wenwei Qian , Yuguang Huang
{"title":"Possible Risk Factors for Severe Complications Occurring after Primary Total Knee Arthroplasty","authors":"Lulu Ma , Xuerong Yu , Xisheng Weng , Jin Lin , Jin Jin , Wenwei Qian , Yuguang Huang","doi":"10.24920/003938","DOIUrl":"10.24920/003938","url":null,"abstract":"<div><h3>Objective</h3><p>Total knee arthroplasty is one of the most common orthopedic surgeries. Readmission due to severe complications after total knee arthroplasty is a grave concern to surgeons. In this study, we evaluated the risk factors for severe complications after primary total knee arthroplasty.</p></div><div><h3>Methods</h3><p>We retrospectively collected clinical data of 2,974 patients who underwent primary total knee arthroplasty from July 2013 to June 2019 in our hospital. Postoperative complication > grade IE was defined as severe complication according to Clavien-Dindo classification system. Binary logistic regression was used to identify the predictive risk factors for severe complications.</p></div><div><h3>Results</h3><p>The complication rate after primary total knee arthroplasty was 6.8% and severe complication rate was 2.5%. Male (<em>OR =</em> 2.178, 95%<em>CI</em>: 1.324-3.585, <em>P</em> = 0.002), individuals above 75 years old (<em>OR =</em> 1.936, 95%<em>CI</em>: 1.155-3.244, <em>P</em> = 0.012), arrhythmia (<em>OR =</em> 2.913, 95%<em>CI</em>: 1.350-6.285, <em>P</em> = 0.006) and cerebrovascular disease (<em>OR</em> = 2.804, 95%<em>CI</em>: 1.432-5.489, <em>P</em> = 0.003) were predictive risk factors for severe complications after primary total knee arthroplasty.</p></div><div><h3>Conclusion</h3><p>Advanced age, male, arrhythmia, and cerebrovascular disease might be patients-related risk factors for postoperative severe complications after primary total knee arthroplasty. Special attention should be paid to patients with risk factors.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"37 4","pages":"Pages 303-308"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9272337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin He , Jianping Ning , Hui Xu , Gong Xiao , Huixiang Yang , Weiyuan Wang , Xiaoying Wu , Hongling Yin , Xiaozhao Li
{"title":"Renal Amyloidosis Secondary to ANCA-Associated Vasculitis: A Case Report","authors":"Xin He , Jianping Ning , Hui Xu , Gong Xiao , Huixiang Yang , Weiyuan Wang , Xiaoying Wu , Hongling Yin , Xiaozhao Li","doi":"10.24920/003999","DOIUrl":"10.24920/003999","url":null,"abstract":"<div><p>Renal amyloidosis secondary to anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is extremely rare. Here, we reported a 77-year-old woman with ANCA-associated vasculitis. Renal biopsy with Masson trichrome staining showed pauci-immune crescentic glomerulonephritis, and electron microscopy showed amyloid deposition in the mesangial area. Immunofluorescence revealed kappa light chain and lambda light chain negative. Bone marrow biopsy revealed no clonal plasma cell. Finally, she was diagnosed as ANCA-associated vasculitis with secondary renal amyloid A amyloidosis.</p></div>","PeriodicalId":35615,"journal":{"name":"Chinese Medical Sciences Journal","volume":"37 4","pages":"Pages 359-362"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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