Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology最新文献

{"title":"The Relation Between Nucb2/Nesfatin-1 Gene Polymorphism with Obstructive Sleep Apnea Severity","authors":"N. Benlier, Nevhiz Gündoğdu, Ayşegül ÇÖRT DÖNMEZ, Deniz Mihcioglu, Erman Kandilli","doi":"10.5505/turkhijyen.2022.93824","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.93824","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Antibacterial Effect of Ciprofloxacin and Green Tea Extract on Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Clinical Cases","authors":"Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz","doi":"10.5505/turkhijyen.2022.90532","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.90532","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70678122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nested-PCR Assay for molecular identification of cutaneous leishmaniasis species using kinetoplast DNA gene in Mirjaveh and Reg-e Malek provinces (IRAN)","authors":"H. Mirahmadi, F. Gorgani, M. Metanat, S. Etemadi, Seyed Mehdi Tabaatabaei̇, Mohammad Kazem Momeni","doi":"10.5505/turkhijyen.2022.06887","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06887","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution and antibiotic susceptibility of microorganisms isolated from blood cultures of patients hospitalized in intensive care units: a two-year evaluation","authors":"Tuğçe Şimşek Bozok, Taylan Bozok","doi":"10.5505/turkhijyen.2022.26937","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.26937","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Treatment Cost by Artificial Neural Network of Patients with COVID-19 in Intensive Care Unit","authors":"Suna Koc, M. Dokur, T. Özer, Betul Borku Uysal, M. Islamoglu, N. Açıkgöz, İlke Küpeli, Sena Koç, Sema Nur Dokur, I. Degim","doi":"10.5505/turkhijyen.2022.48642","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.48642","url":null,"abstract":"Objective: Artificial neural networks (ANNs) are computer systems that are inspired by the biological neural networks that make up mammalian brains. An ANN is built from a network of linked units or nodes known as artificial neurons, which are roughly modeled after the neurons in the human brain. Each link, like synapses in a human brain, has the ability to send a signal to other neurons. The connections are referred to as edges. Neurons and edges usually have a weight that changes as learning progresses. The weight changes the intensity of the signal at a connection. Artificial neural networks have found applications in a wide range of fields due to their capacity to recreate and simulate nonlinear phenomena. System identification and control, medical diagnostics, data mining, visualization, machine translation, distinguishing highly invasive cancer cell lines from less invasive lines using simply cell shape information, and many more domains are examples of application areas. In this study, ANN analysis was utilized by us to forecast the total cost of therapy or the prognosis of severe COVID-19 the patients in the intensive care unit (ICU). Methods: The parameters such as ages, and the other biochemical parameters that affect the staying periods (days) of COVID-19 infected patients in ICU were evaluated by using an ANN analysis. For this a computer program, Pythia®, was used to develop ANN models. Real data was used for that selected patients in this study. Results: The real data obtained from the ICU and gave to the computer as initial parameters. The computer program gave 15 neurons for the first level, one neurons for the second level as the most suitable model for the prediction (SSD = 0.000995). This program predicts a total cost 144.930,94 Turkish Lira (27.300 USD) where the real cost 142.234,06 Turkish Lira (26.792 USD) for the real patient in 2019. This relation was found to be good to predict the possible affected parameters on staying times. Conclusion: The ANN model developed and released in this research does not necessitate any experimental parameters. Besides, ANN has the ability to deliver helpful and exact prediction or information regarding the expense of COVID-19 patients in ICU. © 2022. All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of COVID-19 Cases Detected Positive by RT-PCR","authors":"Vildan Görgülü, Fazıla Atakan Erkal, Şenay Tuğlu Ataman, E. Çiftci, Önder Ser, Elçin YENİDÜNYA KONUK, Fırat Köse","doi":"10.5505/turkhijyen.2022.53496","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.53496","url":null,"abstract":"Objective: Immunization by vaccination has a crucial role in controlling COVID-19 pandemic. Determination of the factors affecting the effectiveness of the vaccine can increase the success rates. We aimed to investigate the effectiveness of CoronaVac and factors affecting its effectiveness in healthcare workers. Methods: This retrospective study included healthcare personnel (n=2666) working at a training and research hospital. Logistic regression analysis was used for analyzing the effects of all variables including vaccination status on the development of COVID-19. Adjusted odds ratios calculated by logistic regression analysis were used to determine the vaccine effectiveness. Stratified analyses wre performed for the determination of the interaction/effect modification regarding the vaccine effectiveness. Results: Mean age of the 2.666 healthcare workers included in this study was 37,3±10,2 and 55,8% (n=1488) were females and %44,2 (n=1178) were males. In this study gender and history of COVID-19 infection was found to be an effect modifier for the vaccine effectiveness by the stratified analysis. The effectiveness of the CoronaVac vaccine in preventing development of COVID-19 diagnosed by real-time polymerase chain reaction (RT-PCR) in healthcare workers was 84,5% (95%CI: 73,3-91) in women and 47% (95%CI: 1,7-71,4) in men. Being a medical doctor or a registered nurse, working in ICU or a COVID-19 clinic, a positive history of COVID-19 and COVID-19 vaccination were other protective factors against COVID-19 infection. Conclusion: Determination of the factors affecting the effectiveness of the vaccine can increase the success rates. Vaccination programs may need to be modified if there is a COVID-19 history or gender-related difference in vaccine effectiveness. © 2022,Turk Hijyen ve Deneysel Biyoloji Dergisi. All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Antinuclear antibodies in pregnant women with abortion with toxocariasis and toxoplasmosis in Iran","authors":"V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr","doi":"10.5505/turkhijyen.2022.69009","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.69009","url":null,"abstract":"Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperglycemia increases Ca2+ realese activated Ca2+ current, ICRAC, in RBL-1 cells","authors":"Y. Gökçe, Taufiq Rahman, N. Yaraş","doi":"10.5505/turkhijyen.2022.06332","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06332","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TBHEB 2022-3 Vol 79 Full Printed Journal","authors":"Utku Ercömert","doi":"10.5505/turkhijyen.2022.32650","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.32650","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of urinary tract infections and causative agents in geriatric patients","authors":"M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner","doi":"10.5505/turkhijyen.2022.19971","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.19971","url":null,"abstract":"Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}