Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology最新文献

{"title":"Evaluation of COVID-19 Cases Detected Positive by RT-PCR","authors":"Vildan Görgülü, Fazıla Atakan Erkal, Şenay Tuğlu Ataman, E. Çiftci, Önder Ser, Elçin YENİDÜNYA KONUK, Fırat Köse","doi":"10.5505/turkhijyen.2022.53496","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.53496","url":null,"abstract":"Objective: Immunization by vaccination has a crucial role in controlling COVID-19 pandemic. Determination of the factors affecting the effectiveness of the vaccine can increase the success rates. We aimed to investigate the effectiveness of CoronaVac and factors affecting its effectiveness in healthcare workers. Methods: This retrospective study included healthcare personnel (n=2666) working at a training and research hospital. Logistic regression analysis was used for analyzing the effects of all variables including vaccination status on the development of COVID-19. Adjusted odds ratios calculated by logistic regression analysis were used to determine the vaccine effectiveness. Stratified analyses wre performed for the determination of the interaction/effect modification regarding the vaccine effectiveness. Results: Mean age of the 2.666 healthcare workers included in this study was 37,3±10,2 and 55,8% (n=1488) were females and %44,2 (n=1178) were males. In this study gender and history of COVID-19 infection was found to be an effect modifier for the vaccine effectiveness by the stratified analysis. The effectiveness of the CoronaVac vaccine in preventing development of COVID-19 diagnosed by real-time polymerase chain reaction (RT-PCR) in healthcare workers was 84,5% (95%CI: 73,3-91) in women and 47% (95%CI: 1,7-71,4) in men. Being a medical doctor or a registered nurse, working in ICU or a COVID-19 clinic, a positive history of COVID-19 and COVID-19 vaccination were other protective factors against COVID-19 infection. Conclusion: Determination of the factors affecting the effectiveness of the vaccine can increase the success rates. Vaccination programs may need to be modified if there is a COVID-19 history or gender-related difference in vaccine effectiveness. © 2022,Turk Hijyen ve Deneysel Biyoloji Dergisi. All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of quality indicators in the field of blood banking and transfusion medicine in Turkey","authors":"Ayse Sakioglu, Sibel Eldemir, İ. Y. Avcı","doi":"10.5505/turkhijyen.2022.62444","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.62444","url":null,"abstract":"As a result of the work initiated by the World Health Organization with the slogan “Safe blood begins with me”, the understanding of quality in blood banking and transfusion medicine has begun to be felt more clearly. In our country, quality studies in transfusion medicine gained momentum with the “Safe blood supply project”. For blood service units, quality has gone beyond the understanding of “write what you do, do what you write” and become a part of the safe blood supply process. The fact that the understanding of the quality management system made its presence felt more intensely created the need for blood service units to express the positive contributions of the quality management system with concrete indicators. Monitoring the processes in transfusion medicine with the quality indicators to be established can be the targeted concrete evidence. Quality indicators are also important for evaluating and comparing the performances of blood service units. There are various studies on establishing quality indicators in transfusion medicine at national and international level. However, quality indicators for transfusion centers were barely mentioned in these studies. There are no standardized quality indicators for transfusion centers at the national level. In our article, ise transfüzyon tıbbı we evaluated the deficiencies in quality indicators in blood banking and transfusion medicine in Turkey. We have developed exemplary quality indicators by making use of international and national studies. We believe that in the future, more comprehensive studies will be carried out and standardized blood banking and transfusion medicine quality indicators approved by the competent authority will","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Antinuclear antibodies in pregnant women with abortion with toxocariasis and toxoplasmosis in Iran","authors":"V. Raissi, Zahra BABAEİ SAMANİ, Mohammadreza Bagherpoor, Z. Sohrabi, S. Etemadi, O. Raiesi, Pantea Jalali, M. Zareie, Gita Alizadeh, Zeynab HASHEMİ BAGHİ, Asmaa Nasr","doi":"10.5505/turkhijyen.2022.69009","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.69009","url":null,"abstract":"Objective: Toxoplasma gondii , Toxocara spp, and antinuclear antibodies (ANAs) have been reported as a cause of abortion. To determine the prevalence rate of T. gondii, Toxocara spp, and ANAs in aborted women, and to investigate the association between infection and the number of the sociodemographic estimated risk factors. Methods: This study was carried out in aborted women referred to the Qaem hospital in Mashhad city (Razavi Khorasan Province). Serum samples were examined for the presence of Antinuclear Antibody (IgG antibodies), anti- Toxoplasma gondii IgG and IgM antibodies, and IgG anti-toxocariasis spp antibodies by ELISA (Enzyme-Linked Immunosorbent Assay) kit. Data like contact with animals’ cats and dogs, age, and Type of cause of abortion (in most cases) were collected as risk factors for the prevalence of infection. T. gondii and Toxocara spp detected in 9%, also ANAs detected in cases with T. gondii in 24% and 10% with Toxocara spp. ANAs showed positivity with co-infection of T. gondii and Toxocara spp in 8%. This study showed a significant association between infection of each T. gondii , Toxocara spp, and ANAs with age and animal contact such as cats and dogs. Conclusion: These study findings indicated that there is a relatively high prevalence of T. gondii , Toxocara spp, and ANAs in pregnant women with abortion. The coexistence of two agents or of one with ANAs increases the risk of abortion. All of them showed association with age and contact with domestic animals like cats","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Antibiotic Use on Microorganism Distribution and Antibiotic Resistance in Hospital Infections in the Covid-19 Pandemic","authors":"A. Habiloğlu, Gönül Çiçek Şentürk, Yunus Gürbüz, Ezgi Gizem Şibar, Esengul Sendag, N. Altin, İ. Şencan","doi":"10.5505/turkhijyen.2022.71135","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.71135","url":null,"abstract":"Objective: COVID-19 pneumonia, which has affected the whole world for more than two years, has forced the health system. In this period, when the delivery of health services is in danger, the use of appropriate antibiotics has remained in the background. With this study, we wanted to investigate the effect of changing antibiotic use during the pandemic period on the distribution of microorganisms that cause nosocomial infections and changing antibiotic resistances. Methods: The study was carried out in the Dışkapı Yıldırım Beyazıt Training and Research Hospital. Hospital-acquired infections caused by E. coli, Klebsiella penumonia, Enterobacter spp., P. aeruginosa and Acinetobacter spp. between 2016 and 2020 were evaluated for our study. We classified the patients in 2016 as 1st group, 2017 as a 2nd group, 2018 as a 3rd group, 2019 as a 4th group, 2020 as a 5th group. The groups were compared with each other in terms of the rate of hospital-acquired infection, their resistance status and the amount of antibiotics used in the relevant years. The factors that showed significant difference only in the 5th year were attributed to the changing health services during the pandemic period and were examined. Results: The most commonly used antibiotic in our study was ceftriaxone with a DDD of 150.72. Piperacillin + tazobactam and levofloxacin were the second and third most commonly used antibiotics, respectively.The amount of piperacillin + tazobactam use attributed to the pandemic period is significantly higher in the 5th group than in the 1st, 2nd, 3rd and 4th groups. Meropenem, levofloxacin, and colistin, which had increased usage during the pandemic period, were not attributed to the pandemic period since they did not differ with all other groups in pairwise comparisons. There was no change in the rates of microorganisms causing hospital infections for the pandemic period. Piperacillin resistance rate at 5th group for K. pneumonia and E. coli was significantly higher than at 1, 2, 3 and 4 groups. There was a positive correlation between the use of piperacillin/tazobactam and piperacillin resistance for K. pneumoniae and E. coli. Conclusion: In our study, we found that the use of piperacillin/tazobactam and levofloxacin in our hospital increased significantly during the pandemic period. There was no significant increase in the correlation between increasing antibiotic use and antibiotic resistance. Resistant strains, which will be triggered by the increasing amount of antibiotic consumption during the pandemic period, will be a problem that should be followed up in the coming years © 2022. Turk Hijyen ve Deneysel Biyoloji Dergisi.All Rights Reserved.","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apilarnil protects the LPS induced endotoxemic heart","authors":"A. Okan, E. Kaymak, Arda Kaan Üner, S. Silici, Z. Doğanyiğit","doi":"10.5505/turkhijyen.2022.78200","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.78200","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relation Between Nucb2/Nesfatin-1 Gene Polymorphism with Obstructive Sleep Apnea Severity","authors":"N. Benlier, Nevhiz Gündoğdu, Ayşegül ÇÖRT DÖNMEZ, Deniz Mihcioglu, Erman Kandilli","doi":"10.5505/turkhijyen.2022.93824","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.93824","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70677818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Antibacterial Effect of Ciprofloxacin and Green Tea Extract on Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Clinical Cases","authors":"Yalçın Di̇cle, H. Yazgi, M. Coskun, Zeynal Topalcengiz","doi":"10.5505/turkhijyen.2022.90532","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.90532","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70678122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperglycemia increases Ca2+ realese activated Ca2+ current, ICRAC, in RBL-1 cells","authors":"Y. Gökçe, Taufiq Rahman, N. Yaraş","doi":"10.5505/turkhijyen.2022.06332","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.06332","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TBHEB 2022-3 Vol 79 Full Printed Journal","authors":"Utku Ercömert","doi":"10.5505/turkhijyen.2022.32650","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.32650","url":null,"abstract":"","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70675990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of urinary tract infections and causative agents in geriatric patients","authors":"M. Ayhan, A. Kaya Kalem, I. Hasanoğlu, B. Kayaaslan, Rahmet Güner","doi":"10.5505/turkhijyen.2022.19971","DOIUrl":"https://doi.org/10.5505/turkhijyen.2022.19971","url":null,"abstract":"Objective: Urinary tract infections are the second most common disease in elderly patients and the most common disease related to bacteria. Due to the immune senescence, comorbid diseases and various physiological changes, susceptibility to such infections may develop with age. It is important to know the common pathogens and resistance profile in this patient population for empirical treatment selection. We aimed to evaluate patient characteristics, causative microorganisms and their resistance in elderly patients hospitalized in our clinic due to urinary tract infection. Methods: Patients who were older than 65 years and hospitalized in Ankara City Hospital Infectious Diseases and Clinical Microbiology clinic with a diagnosis of urinary tract infection between March 2019 and March 2020 were retrospectively evaluated. Hospitalization information, patient files and all medical records on the hospital information processing system in terms of demographic characteristics, culture results and resistance status of the pathogens were screened. YOLU ENFEKSİYONLARI Results: A total of 118 patients were included in the study and the mean age of the patients was 74.65 ± 7.4. hypertension (41.5%), diabetes (30.0%) and dementia (18.6%) were the most common comorbid diseases. Urinary procedure history (11.0%) was the most common complicating factor in the patients. Majority (86.0%) of the causative agents were Gram-negative bacteria. Escherichia coli ( E. coli ) (59.0%) and Klebsiella pneumoniae ( K. pneumoniae ) (17.0%) were the most commonly isolated pathogens, respectively. While extended spectrum beta-lactamase (ESBL) was observed as 56.0% in E. coli and 40.0% in K. pneumoniae , carbapenem resistance was observed at a rate of 20.0% in K. pneumoniae strains. Patients with and without mortality were compared in terms of the presence of resistance (ESBL / carbapenem resistance) and distribution of the infectious agents, and there was no statistically significant difference between the two groups (p=0.573 and p=0.161, respectively). Conclusion: Urinary tract infections are the most common cause of bacteremia in the elderly population and often require hospitalization. Aging is one of the major risk factors for the development of urinary tract infections due to reasons such as urinary incontinence, urinary retention, hospitalizations requiring urinary catheterization, staying in a nursing home and immune aging. It can cause significant morbidity and mortality. In our study, resistance rates were high in the isolated specimens. This should be take into consideration during choosing empiric treatment. Each center should periodically monitor infectious agents and their resistance profiles which observed in their specific patient populations and should develop their own solution strategies to reduce antimicrobial resistance and provide effective treatment to","PeriodicalId":35553,"journal":{"name":"Turk hijiyen ve deneysel biyoloji dergisi. Turkish bulletin of hygiene and experimental biology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70676076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}