重症监护病房COVID-19患者治疗费用的人工神经网络预测

Q4 Medicine
Suna Koc, M. Dokur, T. Özer, Betul Borku Uysal, M. Islamoglu, N. Açıkgöz, İlke Küpeli, Sena Koç, Sema Nur Dokur, I. Degim
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引用次数: 0

摘要

目的:人工神经网络(ann)是受构成哺乳动物大脑的生物神经网络启发的计算机系统。人工神经网络是由被称为人工神经元的连接单元或节点组成的网络构建而成的,人工神经元大致模仿人类大脑中的神经元。每个连接,就像人类大脑中的突触一样,有能力向其他神经元发送信号。这些连接被称为边。神经元和边通常有一个权重,随着学习的进展而变化。权重改变连接处的信号强度。人工神经网络由于其重建和模拟非线性现象的能力,在广泛的领域得到了应用。系统识别和控制、医疗诊断、数据挖掘、可视化、机器翻译、使用简单的细胞形状信息区分高侵袭性癌细胞系和低侵袭性癌细胞系,以及更多的领域都是应用领域的例子。在本研究中,我们利用神经网络分析预测重症监护病房(ICU)重症COVID-19患者的治疗总费用或预后。方法:采用人工神经网络(ANN)分析影响COVID-19感染患者在ICU住院时间(d)的年龄等生化指标。为此,使用了计算机程序Pythia®来开发人工神经网络模型。本研究选取的患者均采用真实数据。结果:从ICU获得的真实数据作为初始参数输入计算机。计算机程序给出第一级15个神经元,第二级1个神经元作为最适合预测的模型(SSD = 0.000995)。该项目预计2019年患者的总成本为144.930,94土耳其里拉(27.300美元),而实际成本为142.234,06土耳其里拉(26.792美元)。该关系可以很好地预测可能影响停留时间的参数。结论:本研究建立并发布的人工神经网络模型不需要任何实验参数。此外,人工神经网络有能力提供有关COVID-19患者在ICU的费用的有用和准确的预测或信息。©2022。版权所有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prediction of Treatment Cost by Artificial Neural Network of Patients with COVID-19 in Intensive Care Unit
Objective: Artificial neural networks (ANNs) are computer systems that are inspired by the biological neural networks that make up mammalian brains. An ANN is built from a network of linked units or nodes known as artificial neurons, which are roughly modeled after the neurons in the human brain. Each link, like synapses in a human brain, has the ability to send a signal to other neurons. The connections are referred to as edges. Neurons and edges usually have a weight that changes as learning progresses. The weight changes the intensity of the signal at a connection. Artificial neural networks have found applications in a wide range of fields due to their capacity to recreate and simulate nonlinear phenomena. System identification and control, medical diagnostics, data mining, visualization, machine translation, distinguishing highly invasive cancer cell lines from less invasive lines using simply cell shape information, and many more domains are examples of application areas. In this study, ANN analysis was utilized by us to forecast the total cost of therapy or the prognosis of severe COVID-19 the patients in the intensive care unit (ICU). Methods: The parameters such as ages, and the other biochemical parameters that affect the staying periods (days) of COVID-19 infected patients in ICU were evaluated by using an ANN analysis. For this a computer program, Pythia®, was used to develop ANN models. Real data was used for that selected patients in this study. Results: The real data obtained from the ICU and gave to the computer as initial parameters. The computer program gave 15 neurons for the first level, one neurons for the second level as the most suitable model for the prediction (SSD = 0.000995). This program predicts a total cost 144.930,94 Turkish Lira (27.300 USD) where the real cost 142.234,06 Turkish Lira (26.792 USD) for the real patient in 2019. This relation was found to be good to predict the possible affected parameters on staying times. Conclusion: The ANN model developed and released in this research does not necessitate any experimental parameters. Besides, ANN has the ability to deliver helpful and exact prediction or information regarding the expense of COVID-19 patients in ICU. © 2022. All Rights Reserved.
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