Japanese Journal of Allergology最新文献_第4页

[POST-TREATMENT SURVEY OF THE MAINTENANCE OF EFFECTS FOR CEDAR SUBLINGUAL IMMUNOTHERAPY]. [雪松舌下免疫治疗后疗效维持情况调查]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.132

Atsushi Yuta, Yukiko Ogawa, Hideaki Kozaki, Koji Matsumoto, Takeshi Shimizu, Mitsuhiro Okano

{"title":"[POST-TREATMENT SURVEY OF THE MAINTENANCE OF EFFECTS FOR CEDAR SUBLINGUAL IMMUNOTHERAPY].","authors":"Atsushi Yuta, Yukiko Ogawa, Hideaki Kozaki, Koji Matsumoto, Takeshi Shimizu, Mitsuhiro Okano","doi":"10.15036/arerugi.75.132","DOIUrl":"10.15036/arerugi.75.132","url":null,"abstract":"We studied post-treatment survey of the maintenance of effects for cedar sublingual immunotherapy (SLIT).Methods: Patients who started between 2018 and 2020 and had completed at least three seasons of SLIT with Cedarcure (post-SLIT patients) were surveyed by mail in 2025, regarding as 1) impressions compared to the time of SLIT completion, 2) the VAS (best 0-worst 100mm) of general symptoms in pollen season at 3 points (pre-SLIT, at the end of SLIT and in 2025), 3) medication score. Responses were received from 200 of 370 patients (age 15 [11-42] years, male 97).Results: The percentages of the maintenance of effects were 61%, 59%, 51% and 34% in order of 1- to 4-year follow-up, respectively (p<0.05 in 4-year vs 1- or 2-year, unadjusted and uncorrected). The VAS for all patients changed 90→10→20 in median at the three time points. On the 2025 VAS, the 4-year follow-up was significantly worse than the 1- and 2-year follow-ups, and the SLIT treated for 3 years was significantly worse than for 4 or 5 years (p<0.05). Compared with currently undergoing SLIT with the same treatment duration, the VAS of post-SLIT patients was significantly worsened in the group of 3 years of treatment, but not in the group of 4 or 5 years. The medication score was 0.3 in median, and there was no difference with currently SLIT patients.Conclusion: Although many patients progressed well, some cases worsened, and the four-year follow-up was significantly worse. A four-year or more treatment is recommended.","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"75 2","pages":"132-141"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[IGG4-RELATED DISEASE: THE FOREFRONT OF DIAGNOSIS AND TREATMENT]. [igg4相关疾病：诊断和治疗的前沿]

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.8

Ichiro Mizushima, Mitsuhiro Kawano

引用次数: 0

[RECURRENT CUTANEOUS INFECTIONS LEADING TO THE DIAGNOSIS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION: A CASE REPORT]. 【反复皮肤感染导致人类免疫缺陷病毒感染的诊断：1例报告】。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.305

Marika Matsuya, Satomi Igawa, Kyoko Kanno, Hikaru Shibaki, Masayo Yamamoto, Mayumi Hatayama, Yasuyuki Fujita

{"title":"[RECURRENT CUTANEOUS INFECTIONS LEADING TO THE DIAGNOSIS OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION: A CASE REPORT].","authors":"Marika Matsuya, Satomi Igawa, Kyoko Kanno, Hikaru Shibaki, Masayo Yamamoto, Mayumi Hatayama, Yasuyuki Fujita","doi":"10.15036/arerugi.75.305","DOIUrl":"10.15036/arerugi.75.305","url":null,"abstract":"A man in his 30s with severe atopic dermatitis presented with recurrent bacterial skin infections over a one-month period, including lower leg cellulitis, persistent impetigo of the buttocks and extremities, and a carbuncle on the back. Despite incision and drainage, the carbuncle failed to improve, and he was referred to our department, requiring hospitalization. During hospitalization, he developed Kaposi varicelliform eruption. He had no known history of immunodeficiency; however, serologic evidence of prior syphilis infection was identified. Further evaluation revealed HIV antigen/antibody testing and an HIV RNA level of 74000copies/mL, leading to a diagnosis of HIV infection.After discharge, his continuing episodes of recurrent carbuncles and furuncles induced him to initiate antiretroviral therapy. Following antiretroviral therapy initiation, his atopic dermatitis improved markedly. In the present case, it was considered that initiation of antiretroviral therapy might be associated with improvement in atopic dermatitis, suggesting that HIV treatment may modulate the activity of inflammatory skin disease.As the cumulative number of individuals living with HIV continues to increase nationwide, recurrent skin and soft tissue infections should prompt consideration of HIV infection, even in non-urban regional settings. Early recognition and appropriate screening are essential for improving clinical outcomes.","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"75 4","pages":"305-309"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148702489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[ACCEPTANCE OF EPINEPHRINE NASAL SPRAY (NEFFY^®) AMONG PEDIATRIC EPIPEN^® CARRIERS AND THEIR PARENTS PRIOR TO ITS LAUNCH IN JAPAN]. [小儿肾上腺素鼻喷雾剂（neffy®）在日本上市前在儿童肾上腺素携带者及其父母中的接受程度]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.396

Shuta Kito, Akinori Goto, Chihiro Tano, Satoshi Mochizuki, Naoko Oike, Joon Nakata, Takae Kobayashi

{"title":"[ACCEPTANCE OF EPINEPHRINE NASAL SPRAY (NEFFY®) AMONG PEDIATRIC EPIPEN® CARRIERS AND THEIR PARENTS PRIOR TO ITS LAUNCH IN JAPAN].","authors":"Shuta Kito, Akinori Goto, Chihiro Tano, Satoshi Mochizuki, Naoko Oike, Joon Nakata, Takae Kobayashi","doi":"10.15036/arerugi.75.396","DOIUrl":"https://doi.org/10.15036/arerugi.75.396","url":null,"abstract":"Background: Epinephrine nasal spray (Neffy®) demonstrates pharmacodynamic effects comparable to epinephrine auto-injector (EpiPen®) and is considered safe. Neffy was approved in Japan on September 19, 2025, as an \"Adjunctive treatment for anaphylactic reactions\" and launched on February 12, 2026. It is expected to become a new option for initial anaphylaxis treatment.Objective: To investigate the acceptance of the new formulation and the background factors influencing that acceptance among pediatric patients and their parents who carry EpiPen before Neffy's distribution.Methods: A questionnaire was delivered online or on paper to pediatric patients carrying EpiPen and their parents/guardians who visited our hospital between November 18 and December 26, 2025.Results: Although awareness was still low before Neffy's distribution, the majority of patients and parents were interested in Neffy. Parents who were more accepting of Neffy reported higher anxiety about carrying EpiPens and had lower confidence in their use. In several cases, a discrepancy existed between the patient's and their parent's acceptance.Conclusion: Moving forward, treatment selection should be based on accurate information and in consultation with both patients and their parents.","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"75 5","pages":"396-410"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[ALLERGEN INFORMATION DISCLOSURE AMONG MAJOR JAPANESE RESTAURANT CHAINS AND USE OF THE SPECIFIED INGREDIENTS ACROSS THEIR MENU ITEMS]. [日本主要连锁餐厅的过敏原信息披露和菜单中特定成分的使用]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.411

Moeko Isono, Makoto Isono

{"title":"[ALLERGEN INFORMATION DISCLOSURE AMONG MAJOR JAPANESE RESTAURANT CHAINS AND USE OF THE SPECIFIED INGREDIENTS ACROSS THEIR MENU ITEMS].","authors":"Moeko Isono, Makoto Isono","doi":"10.15036/arerugi.75.411","DOIUrl":"10.15036/arerugi.75.411","url":null,"abstract":"Background and objective: Creating safer and more inclusive eating-out environments for people with food allergies is an important public health issue. While evidence on safety is accumulating, research on inclusivity for people with food allergies remains limited. This study aimed to describe the current status of allergen information disclosure by major Japanese restaurant brands and to assess the frequency of the specified ingredients in the menu items.Methods: We reviewed the official websites of 100 major Japanese restaurant brands. For each brand, the availability and content of allergen information were recorded, including whether the specified ingredients and the additional designated allergens were listed. For brands with extractable allergen data, the percentage of menu items containing each of the specified ingredients was calculated.Results: Eighty-one brands provided allergen information through at least one of the following: website tables, in-store notices, or upon request. Seventy-one brands published website tables for the specified ingredients, and 60 also listed the additional designated allergens. Among the specified ingredients, wheat appeared in 79.7% of all menu items, followed by egg (45.5%) and milk (41.9%).Conclusion: Even among major restaurant brands, information disclosure on the additional designated allergens remains limited to only about 60% of all brands. Given that wheat was included in approximately 80% of all items, people with wheat allergy may face considerable difficulties when dining out.","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"75 5","pages":"411-420"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[RECONSIDERATION OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS (EGPA)]. [嗜酸性肉芽肿病合并多血管炎（egpa）的再思考]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.1

Norihiro Harada

引用次数: 0

[EVALUATING CHALLENGES IN ALLERGY CARE: INSIGHTS FROM THE SAITAMA PREFECTURE TELEPHONE CONSULTATION PROGRAM FOR ALLERGIC DISEASES]. [评估过敏护理的挑战：来自埼玉县过敏疾病电话咨询计划的见解]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.33

Takeshi Koga, Toshiko Itazawa, Kazuyuki Nakagome, Tomoyuki Soma, Koichiro Nakamura, Kenichi Tokuyama, Makoto Nagata

{"title":"[EVALUATING CHALLENGES IN ALLERGY CARE: INSIGHTS FROM THE SAITAMA PREFECTURE TELEPHONE CONSULTATION PROGRAM FOR ALLERGIC DISEASES].","authors":"Takeshi Koga, Toshiko Itazawa, Kazuyuki Nakagome, Tomoyuki Soma, Koichiro Nakamura, Kenichi Tokuyama, Makoto Nagata","doi":"10.15036/arerugi.75.33","DOIUrl":"10.15036/arerugi.75.33","url":null,"abstract":"Background: In Saitama Prefecture, a telephone consultation program for allergic diseases started in 2018 under the \"Allergic Disease Consultation Office\" initiative.Objective: This study aimed to analyze consultation content and identify the current status and challenges of allergy care in the prefecture.Methods: In total, 1016 consultation records from 2018 to 2025 were analyzed using a qualitative inductive approach. Trends over the fiscal years were examined using the Cochran-Armitage trend test.Results: The records were classified into five main categories. Food allergies were divided into 13 subcategories and 32 codes, while other allergic disease had 13 subcategories. \"Consultation on Medical Visits\" accounted for 237 cases (23.3%), covering specialized care, such as oral food challenge testing, adult food allergy management, systemic therapy for atopic dermatitis, and sublingual immunotherapy. Food allergy-related consultations comprised 668 cases (65.7%), and most were under \"Dietary and Nutritional Guidance\" (106 cases, 10.4%) and \"Management in Educational Settings\" (83 cases, 8.2%). A decrease in food allergy consultations among elementary school children was also noted (z=-2.77, p < 0.01).Conclusion: Telephone consultations effectively visualize community healthcare needs. Future challenges include improving adult allergy services, enhancing support in educational settings, and strengthening interprofessional collaboration.","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"75 1","pages":"33-43"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[CURRENT AND FUTURE PROSPECTS OF HOSPITAL-CLINIC COLLABORATION FOR ASTHMA]. [哮喘医院-诊所合作的现状和未来展望]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.222

Takahiro Tsuburai, Yuko Komase, Hiromi Muraoka, Takeo Inoue, Masamichi Mineshita, Hiroki Nishine

引用次数: 0

[KEY POINTS OF THE 2024 REVISION OF THE JAPANESE GUIDELINES FOR ASTHMA PREVENTION AND MANAGEMENT (JGL2024)]. 【2024年日本哮喘预防与管理指南（jgl2024）修订要点】。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.189

Hisako Matsumoto

引用次数: 0

[THE ROLE OF EOSINOPHILS IN ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS/MYCOSIS: PATHOPHYSIOLOGICAL INSIGHTS FROM MULTI-OMICS ANALYSES]. [嗜酸性粒细胞在过敏性支气管肺曲霉病/真菌病中的作用：来自多组学分析的病理生理学见解]。

Japanese Journal of Allergology Pub Date : 2026-01-01 DOI: 10.15036/arerugi.75.283

Hisashi Sasaki, Jun Miyata, Shigeharu Ueki, Yusuke Kawashima, Yoshinori Hasegawa, Koichiro Asano, Koichi Fukunaga

引用次数: 0