{"title":"[TRP CHANNELS AND ALLERGY].","authors":"Makoto Tominaga","doi":"10.15036/arerugi.74.36","DOIUrl":"https://doi.org/10.15036/arerugi.74.36","url":null,"abstract":"","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"74 2","pages":"36-40"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoshihiro Ito, Jun Akimoto, Naoto Otake, Sei Obuse, Yuto Ogawa, Junichiro Miura, Hitoshi Fujimiya, Sakura Sato, Motohiro Ebisawa
{"title":"[STUDY ON THE USE OF MULTI-ITEM ALLERGY TEST \"DROP SCREEN\" FOR PEDIATRIC ALLERGIC DISEASES].","authors":"Yoshihiro Ito, Jun Akimoto, Naoto Otake, Sei Obuse, Yuto Ogawa, Junichiro Miura, Hitoshi Fujimiya, Sakura Sato, Motohiro Ebisawa","doi":"10.15036/arerugi.74.63","DOIUrl":"https://doi.org/10.15036/arerugi.74.63","url":null,"abstract":"<p><strong>Background: </strong>DropScreen ST-1<sup>®</sup> is a new onsite simultaneous measurement of specific IgE antibodies for multiple allergens using a small amount of blood and has been clinically utilized since 2020. We compared it with ImmunoCap<sup>®</sup> which is conventionally performed for each single allergen and investigated the usefulness for pediatric allergy.</p><p><strong>Method: </strong>Using serum from 244 people who visited an allergy outpatient clinic, specific IgE antibodies were measured using DropScreen ST-1<sup>®</sup> and the concordance rate with ImmunoCap<sup>®</sup> was evaluated, targeting 244 people (under 3 years old). We performed cluster analysis using the Co-Clustering method.</p><p><strong>Results: </strong>The positive concordance rate, negative concordance rate, and judgment concordance rate between DropScreen ST-1<sup>®</sup> and ImmunoCap<sup>®</sup> were 93.5%, 93.0%, and 89.3%, respectively. In the cluster analysis, with a high Fisher exact probability, it was possible to classify it into 9 clusters on the allergen axis and 5 clusters on the patient axis. Allergens such as egg white, ovomucoid, milk, and mites were found to form characteristic clusters. On the patient axis, the group was classified from those who were highly sensitized to various allergens to those who were highly sensitized to specific allergens.</p><p><strong>Conclusion: </strong>DropScreen ST-1<sup>®</sup> and ImmunoCap<sup>®</sup> showed a high correlation. Cluster analysis of sensitization patterns has become possible through a specific IgE test that measures multiple items simultaneously.</p>","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"74 2","pages":"63-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keisuke Yamamoto, Natsuko Masumoto, Keisuke Watanuki, Yasuaki Hagio, Daisuke Nishima, Fumiya Yamashita, Keiko Masuda, Mari Kurokawa, Kazue Nakahara, Sooyoung Lee
{"title":"[A CASE OF INDUCIBLE LARYNGEAL OBSTRUCTION REQUIRED DIFFERENTIATION FROM FOOD-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS].","authors":"Keisuke Yamamoto, Natsuko Masumoto, Keisuke Watanuki, Yasuaki Hagio, Daisuke Nishima, Fumiya Yamashita, Keiko Masuda, Mari Kurokawa, Kazue Nakahara, Sooyoung Lee","doi":"10.15036/arerugi.74.78","DOIUrl":"https://doi.org/10.15036/arerugi.74.78","url":null,"abstract":"<p><p>A 9-year-old girl with a history of stridor and pharyngeal strangury was developed during exercise. The patient was diagnosed with food dependent exercise-induced anaphylaxis (FDEIA) because stridor occurred after wheat ingestion and exercise provocation test at the age of ten. Although the patient restricted intake of wheat before exercise, stridor and disturbance of consciousness occurred after exercise and did not respond to adrenaline injection. We suspected exercise-induced anaphylaxis or exercise-induced laryngeal obstruction. Although the patient restricted exercise, similar symptoms occurred even with psychological anxiety and nervousness. Laryngoscopy at the age of eleven during an attack revealed vocal cord closure on inhalation and the patient was diagnosed with inducible laryngeal obstruction (ILO). The symptoms of ILO are similar to the respiratory symptoms of FDEIA in some aspects, but the main symptom is stridor and not responsive to treatment. Appropriate diagnosis of ILO could avoid induction of symptoms and inappropriate treatment.</p>","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"74 2","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[JAPANESE PEDIATRIC GUIDELINES FOR THE TREATMENT AND MANAGEMENT OF ASTHMA (2023)].","authors":"Mizuho Nagao","doi":"10.15036/arerugi.73.255","DOIUrl":"10.15036/arerugi.73.255","url":null,"abstract":"","PeriodicalId":35521,"journal":{"name":"Japanese Journal of Allergology","volume":"73 3","pages":"255-259"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140946234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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