Prague medical report最新文献_第9页

Rare Location of a Dermoid Cyst in the Parotid Gland: A Case Report. 罕见的腮腺皮样囊肿1例报告。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.18

Michal Vavro, Samuel Horák, Bronislava Dvoranová, Zuzana Čierna, Pavel Babál, Daniela Kobzová, Dušan Hirjak, Ladislav Czakó

引用次数: 2

Impact of Hemorrhagic Stroke on Molar Bite Force: A Prospective Study. 出血性中风对磨牙咬合力影响的前瞻性研究。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.16

Gabriel Pádua da Silva, Edson Donizetti Verri, Marcelo Palinkas, Camila Roza Gonçalves, Paula Napolitano Gonçalves, Robson Felipe Tosta Lopes, Guilherme Gallo Costa Gomes, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo

{"title":"Impact of Hemorrhagic Stroke on Molar Bite Force: A Prospective Study.","authors":"Gabriel Pádua da Silva, Edson Donizetti Verri, Marcelo Palinkas, Camila Roza Gonçalves, Paula Napolitano Gonçalves, Robson Felipe Tosta Lopes, Guilherme Gallo Costa Gomes, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo","doi":"10.14712/23362936.2022.16","DOIUrl":"https://doi.org/10.14712/23362936.2022.16","url":null,"abstract":"Stroke is a neurological deficit of cerebrovascular origin that promotes physical impairments of adult individuals. The present study is aimed to demonstrate whether hemorrhagic stroke affects the maximum molar bite force. The prospective study carried in Centro Universitario Claretiano de Batatais, Brazil, determined the distribution of the sample into two groups: hemorrhagic stroke group (n=18, median age, 62.5 years) and disease-free group (n=18, median age, 62.0 years), with 10 men and 8 women in each group. Subjects were paired one-to-one (age and body mass index). The dynamometer was used to measure the maximum molar bite force (right and left). All analyses were performed with a significance level of 5% (Student's t-test). Differences were found on the right (p=0.048) and left (p=0.042) molar bite force, with lower bite force (both sides) in hemorrhagic stroke group. The study suggests that hemorrhagic stroke negatively affects the maximum molar bite force and necessitates changes in food intake to nutritious and softer consistency foods.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 3","pages":"181-187"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40360322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Correlation between Platelet Profile (Mean Platelet Volume, Platelet Volume Distribution Width and Plateletcrit) with Procalcitonin and C-reactive Protein in Critically Ill Children. 危重患儿血小板谱(平均血小板体积、血小板体积分布宽度和血小板电积)与降钙素原和c反应蛋白的相关性

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.8

R. Saragih, G. N. Yanni

{"title":"Correlation between Platelet Profile (Mean Platelet Volume, Platelet Volume Distribution Width and Plateletcrit) with Procalcitonin and C-reactive Protein in Critically Ill Children.","authors":"R. Saragih, G. N. Yanni","doi":"10.14712/23362936.2022.8","DOIUrl":"https://doi.org/10.14712/23362936.2022.8","url":null,"abstract":"The early detection of sepsis can be highly beneficial for the treatment and prognosis of critically ill children. Bacterial culture is the gold standard of bacterial infection, but it takes considerable time to get the result. Some biomarkers had been used as infection markers in children, such as C-reactive protein (CRP), full blood count with differential count and procalcitonin level. Platelet profile had been linked to infection in many studies. Platelet profile consists of mean platelet volume, platelet volume distribution width and plateletcrit. Platelet profiles are relatively inexpensive and widely available examination. It is routinely measured by automated hematology analysers in routine full blood examination, but its clinical importance and application is still limited, especially in children. The aim of this study is to analyse the correlations between platelet profiles with procalcitonin and CRP in critically ill children. A cross sectional study was conducted at Haji Adam Malik Hospital Medan, Indonesia. Patients admitted to paediatric intensive care unit, aged 1 month to 18 years were recruited. Platelet profile, procalcitonin and CRP were measured within 24 hours after admission at PICU. The most common indication of PICU admissions were central nervous system (27.9%) and respiratory (25.3%) disorders. Both MPV (r=0.217; p=0.045) and PDW (r=0.23; p=0.033) had statistically significant correlation with procalcitonin, while none of platelet indicators had significant correlation with CRP. PDW and MPV had statistically significant correlation with procalcitonin as a marker of bacterial infection, their roles as an initial marker of bacterial infection needs further research.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 2 1","pages":"82-87"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67044985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumomediastinum: A Rare Complication of Endobronchial Ultrasound Guided Fine Needle Aspiration. 纵隔气肿:支气管超声引导下细针抽吸的一种罕见并发症。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.5

B. Saha

引用次数: 1

ADHD - What Is the Meaning of Sex-dependent Incidence Differences? ADHD -性别依赖性发病率差异的意义是什么?

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.20

Jindřich Mourek, Jaroslav Pokorný

{"title":"ADHD - What Is the Meaning of Sex-dependent Incidence Differences?","authors":"Jindřich Mourek, Jaroslav Pokorný","doi":"10.14712/23362936.2022.20","DOIUrl":"https://doi.org/10.14712/23362936.2022.20","url":null,"abstract":"There is a clear experience in clinical practice: boys with a diagnosis of ADHD are clearly in greater numbers than girls. It is noteworthy that even in the \"older\" review articles, the cause of sex-dependent incidence is not mentioned. If we accept the neurodevelopmental hypothesis of such disorder, then the possible genetic predisposition breaks down into two separate groups. On the genome of an individual with ADHD and on the genome of the parents. However, it cannot be overlooked that the incidence of ADHD (3-7%) corresponds to the incidence and sex differences of the number of newborns born at a certain risk (premature birth, immaturity, hypotrophy, hypoxic-ischemic syndrome, low birth weight, etc.). This association of possible genetic predisposition with \"external\" risks in the genesis of ADHD raises the question of whether a higher incidence of ADHD, as well as higher morbidity and mortality in males, are a) the norm and the female is privileged, or b) the female is the norm and the male is handicapped. The picture of ADHD includes various cognitive dysfunctions with one possible cause in norepinephrine and dopamine insufficiency. Experimental work shows that in response to stress females release more catecholamines in the CNS than males. Since catecholamines stimulate membrane Na+ K+ ATPase activity, this means both the value of the membrane potential and the threshold for activation is increased. Females are more successful in responding to and adapting to a stressful situation due to their higher production of noradrenaline in the CNS.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 4","pages":"215-224"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40480349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Affecting Drug Exposure after Inhalation. 影响吸入后药物暴露的因素。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.13

Anežka Nováková, Martin Šíma, Ondřej Slanař

引用次数: 0

Liposteroid Therapy for Idiopathic Pulmonary Hemosiderosis: A Scoping Review of the Literature. 类脂激素疗法治疗特发性肺血肿：文献综述。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.7

Biplab K Saha, Nils T Milman

{"title":"Liposteroid Therapy for Idiopathic Pulmonary Hemosiderosis: A Scoping Review of the Literature.","authors":"Biplab K Saha, Nils T Milman","doi":"10.14712/23362936.2022.7","DOIUrl":"10.14712/23362936.2022.7","url":null,"abstract":"Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of diffuse alveolar hemorrhage (DAH). Glucocorticosteroids (CS) represent the first line therapy for IPH. Although most patients respond to CS, steroid refractoriness is seen in an appreciable minority of patients. This paper reviews and evaluates the efficacy and safety profile of liposomal dexamethasone 21-palmitate (liposteroid) for the treatment of IPH. Medline, Embase and Web of Science biomedical databases were searched between 1980 and 2020 to identify papers describing patients with IPH, who were treated with liposteroid. A total of five articles were identified. Four in the form of case reports and one as a case series. A total of 12 pediatric patients (5 boys, 7 girls) were identified, with a median age of 2.3 years (range 0.5-8.6). Liposteroid therapy in intravenous doses ranging 0.06-0.1 mg/kg body weight appeared to be effective for both remission induction therapy, and maintenance therapy. There was no mortality among patients treated with liposteroid, either in the acute phase or during follow-up. The majority of patients for whom long-term follow-up data were available, were cured or in disease remission. No acute adverse events were reported, and long-term side effects were minimal and tolerable. Liposteroid represents a potential alternative or supplement to conventional CS therapy, as it appears to be more efficacious and associated with fewer side effects. Larger prospective, controlled trials are necessary to be able to define more precisely the therapeutic role of liposteroid in IPH.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 2 1","pages":"65-81"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67044887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Course of COVID-19 and Cycle Threshold in Patients with Haematological Neoplasms. 血液肿瘤患者COVID-19的临床病程与周期阈值。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.23

Ignacio Martín Santarelli, Mariela Sierra, María Lucía Gallo Vaulet, Marcelo Rodríguez Fermepin, Sofía Isabel Fernández

{"title":"Clinical Course of COVID-19 and Cycle Threshold in Patients with Haematological Neoplasms.","authors":"Ignacio Martín Santarelli, Mariela Sierra, María Lucía Gallo Vaulet, Marcelo Rodríguez Fermepin, Sofía Isabel Fernández","doi":"10.14712/23362936.2022.23","DOIUrl":"https://doi.org/10.14712/23362936.2022.23","url":null,"abstract":"The SARS-CoV-2 viral load in a respiratory sample can be inversely quantified using the cycle threshold (Ct), defined as the number of amplification cycles required to detect the viral genome in a quantitative PCR assay using reverse transcriptase (RT-qPCR). It may be classified as high (Ct < 25), intermediate (25-30) and low (Ct > 30). We describe the clinical course of 3 patients with haematological neoplasms who contracted COVID-19. None of them had been vaccinated. Firstly, a 22-year-old male with a refractory acute lymphoblastic leukaemia experienced an oligosymptomatic COVID-19 and had a Ct of 23 with an ascending curve. Another male, aged 23, had recently begun treatment for a promyelocytic leukaemia. He had a subacute course with high oxygen requirements. His Ct dropped from 28, when he only experienced fever, to 14.8, during the most critical period and on the edge of ventilatory support. Viral clearance was documented 126 days after the beginning of the symptoms. Finally, a 60-year-old male had received rituximab as maintenance therapy for a follicular lymphoma 3 months before contracting COVID-19. He had a fulminant course and required mechanical ventilation a few days later. We highlight the association between the course of CoViD-19 and the Ct. Viral shedding was longer than in immunocompetent hosts.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 4","pages":"250-257"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40482761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Inferior Alveolar Nerve Transection on the Inorganic Component of Molars of Rat Mandible. 下牙槽神经切断对大鼠下颌骨磨牙无机成分的影响。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.1

I. Němec, V. Smrcka, M. Mihaljevič, M. Hill, J. Pokorný, V. Paral, Ivana Prackova

{"title":"Effect of Inferior Alveolar Nerve Transection on the Inorganic Component of Molars of Rat Mandible.","authors":"I. Němec, V. Smrcka, M. Mihaljevič, M. Hill, J. Pokorný, V. Paral, Ivana Prackova","doi":"10.14712/23362936.2022.1","DOIUrl":"https://doi.org/10.14712/23362936.2022.1","url":null,"abstract":"The objective of the study was to determine the effects of inferior alveolar nerve transection on inorganic components in mandibular molars of the rat. We used 26 male laboratory rats of the Wistar strain for the study, age 7-9 weeks. The rats were divided in three groups. The control group (intact) included 6 rats. The surgery was performed under general anesthesia. The experimental group included (group with the nerve transected on the left) included 12 rats. The sham group (group with the nerve prepared without transection) included 8 rats. The animals were sacrificed after 4 weeks. Molars from the left and right sides of the mandible were extracted. Element content levels were determined using inductively coupled plasma mass spectrometry. The following elements were determined in all samples: magnesium (Mg), sodium (Na), potassium (K), calcium (Ca), zinc (Zn), and strontium (Sr). The nerve transection caused: a reduction of the contents of Ca and Sr in the mandibular molars; an increase in the contents of Mg and Zn; a difference arrangement of both sides for Na. The surgery approach itself caused a decrease in the contents of Na and K in the experimental and sham groups; the difference in K in M3 between the left and right sides disappeared due to the surgery. Our results have confirmed the hypothesis of inferior alveolar nerve transection having an effect on inorganic components in mandibular molars in the rat.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 1 1","pages":"5-19"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67044363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intervertebral Disc Degeneration: Functional Analysis of Bite Force and Masseter and Temporal Muscles Thickness. 椎间盘退变:咬合力、咬肌和颞肌厚度的功能分析。

Prague medical report Pub Date : 2022-01-01 DOI: 10.14712/23362936.2022.11

N. Bettiol, S. Regalo, F. A. Cecílio, L. Gonçalves, P. D. de Vasconcelos, Claire Genoveze Gauch Lopes, L. Andrade, I. Regalo, S. Siéssere, M. Palinkas

{"title":"Intervertebral Disc Degeneration: Functional Analysis of Bite Force and Masseter and Temporal Muscles Thickness.","authors":"N. Bettiol, S. Regalo, F. A. Cecílio, L. Gonçalves, P. D. de Vasconcelos, Claire Genoveze Gauch Lopes, L. Andrade, I. Regalo, S. Siéssere, M. Palinkas","doi":"10.14712/23362936.2022.11","DOIUrl":"https://doi.org/10.14712/23362936.2022.11","url":null,"abstract":"Intervertebral disc degeneration is a pathological condition associated with the intervertebral disc and is related to functional alterations in the human body. This study aimed to evaluate the maximum molar bite force and masseter and temporal muscles thickness in individuals with intervertebral disc degeneration. Thirty-two individuals were divided into two groups: those with degeneration of intervertebral discs (n=16) and those without degeneration (n=16). The maximum molar bite force (on the right and left sides) was measured using a dynamometer. Masseter and temporal muscle thickness during mandibular task rest and dental clenching in maximum voluntary contraction were analysed using ultrasound. Significant differences in the left molar bite force (p=0.04) were observed between the groups (Student's t-test, p<0.05). The intervertebral disc degeneration group had a lower maximum molar bite force. No significant differences in muscle thickness were observed between the masseter and temporal muscles in either group. However, based on clinical observations, the group with intervertebral disc degeneration presented less masseter muscle thickness and greater temporal muscle thickness in both mandibular tasks. Degenerative disease of the intervertebral discs promoted morphofunctional changes in the stomatognathic system, especially in maximum molar bite force and masticatory muscle thickness. This study provides insight into the interaction between spinal pathology and the stomatognathic system, which is important for healthcare professionals who treat patients with functional degeneration.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"123 2 1","pages":"101-112"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67044541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4