Medicine and Materials最新文献

{"title":"ANTIMICROBIAL ACTIVITY OF CHELIDONIUM SPECIES MAJUS L.","authors":"Olimpia Dumitriu Buzia, Geanina Mihaela Ion, K. Earar, G. Gurau, Nela Mardare","doi":"10.36868/medmater.2022.02.01.031","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.031","url":null,"abstract":"The present paper has as main objective the determination of the antimicrobial and antifungal activity of some pharmaceutical forms obtained in the laboratory of pharmaceutical technology of the Faculty of Pharmacy of the University \"Lower Danube of Galati\". We used semi-solid pharmaceutical forms with different concentrations of soft extract of Chelidonium majus L, 50%, 25% and 10% in two ointment bases, simple ointment and base III I performed the antimicrobial activity for all four ointments, compared to extract 1: 3.75 in hydroalcoholic solution (ethyl alcohol / water 35/65 by mass) from aerial parts of Chelidonium majus and alcohol 70 °. hydroalcoholic solution was obtained by cold preparation from the aerial parts of the plant Chelidonium majus. We determined the antimicrobial activity by the diffusimetric method (Kirby-Bauer) and the dilution method. The 50% concentration ointment (UNG A) shows activity on some Gram-negative and Gram-positive bacteria and not on the fungus Candida albicans.","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121635222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE VALUE OF PARACLINICAL EXAMINATIONS IN ORAL PATHOLOGY IN CHILDREN AND YOUNG PEOPLE WITH SOME BLOOD DISCRASIONS","authors":"M. Decusară, M. Pacurar","doi":"10.36868/medmater.2022.02.01.017","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.017","url":null,"abstract":"Blood diseases cause changes in oral structures, the analysis, diagnosis and interpretation of which often present particular difficulties for several reasons. Based on these considerations, the aim of the present study is to evaluate a group of patients with blood dyscrasias –all and anemia, in terms of the correlation between disease status and oral manifestations. The study group consisted of 55 children and young people, aged 6-18, hospitalized in the Clinical Hospital for Children in Galati. A control group of 68 children, of the same age and with a similar distribution by sex, selected from the patients examined and treated in two school offices, was used for comparison. Thus, the relative viscosity of the parotid saliva is 1.5 of the submandibular saliva of 3.4 and of the sublingual saliva of 13.4. Viscosity also depends on the amount of mucin, which in turn is inversely proportional to the amount of secreted saliva. In conditions such as blood dyscrasias, the rate of resting salivary flow and the rate of stimulated salivary flow decrease, thus increasing both carioactivity and individual cariogenic risk","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121186730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHYSIOLOGICAL AND PATHOLOGICAL ASPECTS OF THE AGING PROCESS","authors":"D. Virvescu, D. Frățilă","doi":"10.36868/medmater.2022.02.01.039","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.039","url":null,"abstract":"Demographic changes in the world have begun to raise concerns among experts that health systems, pension funds, as well as health insurance companies and the public funding system will be affected in the long run, changes that will be severely affected by the rapid growth of population. The extent of older people's needs is growing and includes environmental, psychological, social, educational and financial functional confluences as well as physiological and structural problems. The elderly challenge the health care systems due to multiple levels of their needs. In general, medical problems are the result of poor nutrition, deviation of physiological constants, disorders in regulating the inflammatory reaction, walk disorder, immobility, confusion, syncope, sleep disorders. As a result, even the road to the pharmacy can be a torment. The physiological changes that occur as we age are undeniable. The most common visible changes are related to greying hair, changes in the perception of the sense organs, changes in the appearance of the skin, muscle tone, etc. Loss of vision may be a barometer of the onset of aging in somatically healthy patients","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133415893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRINCIPLES OF REMOVABLE DENTURE THERAPY","authors":"D. Frățilă","doi":"10.36868/medmater.2022.02.01.009","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.009","url":null,"abstract":"An important field of gerontology is the determination of a person’s biological age, in order to assess the changes produced in the body as time elapses. A considerable amount of research work conducted in this direction has proven that the morphological, physiological, biochemical, psychological and social involution changes are not identical in individuals of the same age, as such, the biological age does not usually correspond to the chronological, calendar age. Each individual has his/her own rate of aging, which follows more or less the physiological development of the senescence process. One of the most important categories of patients who go to the dentist today is the elderly. They usually present with a complex pathology due to the loss of a large number of dental units (very often subtotal edentulism), due to complications that have occurred over time and, last but not least, due to the pathophysiological specificity of this category of patients. The pathological conditions caused by the significant changes underwent by the dento-maxillary system functions may trigger severe homeostasis impairment in the remaining alveolar bone, in the oral mucosa, of the temporo-mandibular joint, of the masticatory and perioral muscles, as well as of the nervous system of the edentulous patient. Edentulism is an abnormal clinical condition in which the morphological and functional alteration processes were triggered long before, i.e. at the time of onset of the diseases that determined it.","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123966490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRACTICAL ASPECTS OF THE USE OF ACRYLIC BIOMATERIALS IN DENTAL MEDICAL PRACTICE","authors":"A. Mostovei","doi":"10.36868/medmater.2022.02.01.025","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.025","url":null,"abstract":"The aim of this study is to identify the technological peculiarities of the use of bio-acrylic materials in accordance with the clinical parameters of the case, arguing the usefulness of these biomaterials in everyday dental medical practice.A number of 25 partially mobilizable acrylic prostheses were made from different types of biomaterials following the clinical-technological algorithm specific to their type of prosthesis.The variety of clinical cases in which we used acrylic biomaterials as a result of careful analysis of all clinical factors, paraclinical, provides a clear picture of the corroboration of the general condition with local and loco-regional features of the clinical case with the chosen mobilizable therapeutic solution.Partially removable acrylic prostheses remain a viable transient therapeutic solution, in social cases taking on a long-term character managing to ensure a good quality of life through the evolved structure of new acrylic biomaterials in the context of rehabilitation of all stomatognathic system functions.","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126821930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SEPSIS WITH ORAL ENTRY GATE IN IMMUNE DEPRESSED PATIENTS - A CHALLENGE TO CURRENT MEDICAL PRACTICE","authors":"Oleg Solomon","doi":"10.36868/medmater.2022.02.01.003","DOIUrl":"https://doi.org/10.36868/medmater.2022.02.01.003","url":null,"abstract":"\"Sepsis occurs especially in people with a compromised immune system. Hosts become immunocompromised by chronic conditions, HIV, neoplasms, diabetes, as well as immunosuppressive and cytotoxic treatments. This first research direction aims at conducting an etiopathogenic study on a representative group of patients diagnosed with severe sepsis with oral gateway, following the prevalence and incidence of each clinical entity in the corroborative context of a range of factors influencing the final results, outlining with the real image of a complex pathology on the territory of Moldova is very accurate, aspects with a profound impact in the therapeutic approach both for severe sepsis and for the prophylactic methods of oral pathology. For the clinical study, a representative group of patients was studied: 94 patients hospitalized in the Galați Infectious Diseases Clinic between 2018 and 2019. Patients included in the study group, anchored in the territory of immunosuppression, have a general condition affected by: diabetes mellitus, chronic hepatitis, liver cirrhosis, alcoholism, neoplasms, chronic renal failure, anemia. Age is an important factor in the evolution of sepsis. This study also highlighted a phenomenon described in the literature, namely that there is an increased incidence of sepsis in patients of extreme age.\"","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115128998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE CLINICAL-BIOLOGICAL EFFECTS OF PERIODONTAL CURETTAGE IN DENTAL PRACTICE","authors":"R. Feier, Gheorghe Raftu, M. Mariș, A. Caraiane, Constanta Romania Pharmacy","doi":"10.36868/medmater.2021.01.01.053","DOIUrl":"https://doi.org/10.36868/medmater.2021.01.01.053","url":null,"abstract":"Periodontal curettage is one of the basic procedures in marginal periodontium surgery. It is performed during the initial treatment phase of periodontal diseases, which occurs after emergency treatment (when appropriate) of acute complications of chronic marginal periodontal diseases. Periodontal curettage may be divided according to the area where it is performed in: gingival periodontal curettage, subgingival periodontal curettage. Gingival periodontal curettage is performed in the gingival groove and in the false gingival pockets, without usually exceeding the junctional epithelium insertion area. The main objective of subgingival periodontal curettage is to restore gingival health by removing from the root surface the factors that can cause gingival inflammation. The personal study was performed on two groups which included 82 patients. When analyzing the results, we relied on the justified assumption of the study that each case in the large framework of periodontal diseases represents a particular clinical-radiological and etiological reality as concerns its frequency and evolution (especially in terms of complications). The social origin and the cultural background play a very important role in the development of this relationship, which is at its best when both the doctor and the patient are closer from these points of view.","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130803566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BIOTERRORISM AND BIOSECURITY – RISK ANALYSIS AND SPECIFIC PREVENTION","authors":"M. Diac, R. P. Iași, N. Girlescu, S. Damian, A. Knieling, D. Iliescu","doi":"10.36868/medmater.2021.01.01.031","DOIUrl":"https://doi.org/10.36868/medmater.2021.01.01.031","url":null,"abstract":"Microorganisms with lethal potential for human body and the toxins they produce have their own place in history, because of the numerous epidemics they have caused and because of the large number of human lives they have taken. They are a hidden enemy, extremely insidious and with high mortality rates and they can destroy all the defence, control, and medical systems of a state; they can kill many people before anyone can realise the true phenomenon; they can hide the criminals before even suspecting the crime, and they can create chaos, terror, and even economic collapse. Furthermore, we have to analyse the conceptual mutations of the terrorist phenomenon in the last decade. It tends to be a mass destruction act rather than a manipulation and ideologic movement. We can truly say that bioterrorism is the scariest scenario of all existing threats and the main question remains: are all international systems ready to face this enemy and is there a prevention protocol that could be adapted realistically to these threats?","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121149539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIGESTIVE DISORDERS IN THE ORAL CAVITY","authors":"K. Earar, Galati Romania Pharmacy, Dragos Nicola Fratila","doi":"10.36868/medmater.2021.01.01.023","DOIUrl":"https://doi.org/10.36868/medmater.2021.01.01.023","url":null,"abstract":"The progress made in fundamental medical research over the past decades, the scientific acquisitions in the field of genetics, molecular biology and biochemistry in relation to the explosive development of investigative technologies have revolutionized the clinical approach to many pathological entities, practically opening a new era in the evolution of clinical medicine. Dental medicine, as a science, feels the massive impact of the needs for knowledge and relaunches the interest of research in all its subspecialties. From this perspective, these are legitimized not only through the crisis in managing the immense volume of information, but also through the openings offered to the framework of conceptualizing and defining the identity of this branch of medicine, related to the need to particularize the specific problems in this discipline. Digestion is a fundamental process in the survival of an organism. It begins in the oral cavity, where the bolus is formed, and continues in the stomach, forming the chyme, which then reaches the small intestine and transforms into the chyle. Through mastication, the surface of food increases, thus the enzymes are able to act more easily on the substrate. The first enzymes to act on food are the salivary ones - salivary amylase, lingual lipase. Mastication is regulated through the contact of food with receptors in the oral cavity. These will send impulses by way of the trigeminal nerve towards the centre of mastication - located in the bolus. From the bolus, they will start the signals on the efferent pathway (trigeminal, hypoglossal and facial nerves) that will reach the masticatory muscles. Mechanical digestion (mastication) can thus begin. Mechanical digestion in the oral cavity results from mastication. During mastication, the food is manipulated by the tongue, crushed by the teeth and mixed with saliva. Concomitant with mechanical digestion, the chemical digestion takes place through the action of saliva. There are two types of salivary glands in the oral cavity: large glands - parotid, sublingual, submandibular and small glands - disseminated throughout the oral cavity. Within 24 hours, up to 1.5 liters of saliva are secreted, 99% of which is represented by water. The remaining 1% consists of enzymes, mucus, nitrogen content. After finalizing mastication, deglutition begins. This mechanical process consists of thrusting the bolus from the mouth towards the stomach, using the esophagus.","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121893004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AESTHETICS-DENTAL STRUCTURE PRESERVATION AND RESTORATION METHOD","authors":"A. Caraiane, Constanta Romania Pharmacy, M. Antohe, C. Olteanu, M. Pacurar, A. Dimofte, R. P. Iași","doi":"10.36868/medmater.2021.01.01.043","DOIUrl":"https://doi.org/10.36868/medmater.2021.01.01.043","url":null,"abstract":"","PeriodicalId":353170,"journal":{"name":"Medicine and Materials","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114221093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}