ANTIMICROBIAL ACTIVITY OF CHELIDONIUM SPECIES MAJUS L.

Abstract

The present paper has as main objective the determination of the antimicrobial and antifungal activity of some pharmaceutical forms obtained in the laboratory of pharmaceutical technology of the Faculty of Pharmacy of the University "Lower Danube of Galati". We used semi-solid pharmaceutical forms with different concentrations of soft extract of Chelidonium majus L, 50%, 25% and 10% in two ointment bases, simple ointment and base III I performed the antimicrobial activity for all four ointments, compared to extract 1: 3.75 in hydroalcoholic solution (ethyl alcohol / water 35/65 by mass) from aerial parts of Chelidonium majus and alcohol 70 °. hydroalcoholic solution was obtained by cold preparation from the aerial parts of the plant Chelidonium majus. We determined the antimicrobial activity by the diffusimetric method (Kirby-Bauer) and the dilution method. The 50% concentration ointment (UNG A) shows activity on some Gram-negative and Gram-positive bacteria and not on the fungus Candida albicans.