Turkiye parazitolojii dergisi最新文献

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The Bibliometric Analysis of the Postgraduate Theses Written on Medical Parasitology in Türkiye. 对土耳其医学寄生虫学研究生论文的文献计量分析。
Turkiye parazitolojii dergisi Pub Date : 2024-06-30 DOI: 10.4274/tpd.galenos.2024.60948
Selahattin Aydemir, Fethi Barlık, Ekici Abdurrahman, Hasan Yılmaz, Kenan Kaçak
{"title":"The Bibliometric Analysis of the Postgraduate Theses Written on Medical Parasitology in Türkiye.","authors":"Selahattin Aydemir, Fethi Barlık, Ekici Abdurrahman, Hasan Yılmaz, Kenan Kaçak","doi":"10.4274/tpd.galenos.2024.60948","DOIUrl":"https://doi.org/10.4274/tpd.galenos.2024.60948","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to analyze the theses prepared in the field of medical parasitology in Türkiye and to reveal the importance given to the science of parasitology in the groves of academe and to raise awareness in this field.</p><p><strong>Methods: </strong>Council of Higher Education's National Thesis Center database has been analyzed postgraduate these documents conducted in the field of medical parasitology from January 1985 to September 2022.</p><p><strong>Results: </strong>As a result of the examining, 393 theses made in the field of medical parasitology were detected. It was determined that 52.9% of the theses prepared were master, 28% of PhD and 19.1% were the thesis of medical specialty thesis and 61.3% of the theses prepared were related to protozoa, 16.5% of helminths, 8.6% arthropods and 12.2% of intestinal parasites (helminth and protozoa). The top five types of parasites in the theses were <i>Toxoplasma gondii, Leishmania</i> spp., <i>Echinococcus</i> spp., <i>Giardia intestinalis</i> and <i>Cryptosporidium</i> spp. respectively.</p><p><strong>Conclusion: </strong>In conclusion, it was of the opinion that more importance should be given to the field of medical parasitology in Türkiye.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 2","pages":"105-110"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acanthocephala Species of Mammals in Türkiye and A New Species Record from Foxes. 图尔基耶的哺乳动物 Acanthocephala 种类和来自狐狸的新物种记录。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2023.92063
Mehmet Öztürk, Şinasi Umur
{"title":"Acanthocephala Species of Mammals in Türkiye and A New Species Record from Foxes.","authors":"Mehmet Öztürk, Şinasi Umur","doi":"10.4274/tpd.galenos.2023.92063","DOIUrl":"10.4274/tpd.galenos.2023.92063","url":null,"abstract":"<p><p>Acanthocephaliasis is a zoonotic parasitic infection of vertebrates. The phylum Acanthocephala contains nearly 1500 acanthocephalan species. The Archiacanthocephala class is observed in terrestrial habitats and usually has a large, spineless trunk. Acanthocephalans are parasitic worms that use insects as intermediate hosts in their two-host life cycles. Insects, millipedes, and crustaceans in terrestrial areas serve as intermediate hosts and birds and mammals as definitive hosts. Acanthocephalans collected from the red fox (<i>Vulpes vulpes</i>) found dead on the road to Sarıkamış-Kars in 1995 and stored in formaldehyde were kept in Ondokuz Mays University Faculty of Veterinary Medicine, Veterinary Parasitology Laboratory Museum until 2023 after our parasitological study found an infected red fox with <i>Pachysentis</i> sp. This study provides the anatomy of the acanthocephalans and the laboratory practice necessary for a good and reliable diagnosis. This study reports a new species, <i>Pachysentis</i> sp., of acanthocephalan (thorny-headed worm) found in red foxes for Türkiye. On the basis of relevant articles, we have created a key to Acanthocephala species occurring in mammals.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"66-71"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of Intestinal Parasites in Patients Admitted to University Hospital: Four Year Retrospective Review. 大学医院住院病人肠道寄生虫的分布:四年回顾
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2024.03521
Fatma Günbey, Zülal Aşçı Toraman
{"title":"Distribution of Intestinal Parasites in Patients Admitted to University Hospital: Four Year Retrospective Review.","authors":"Fatma Günbey, Zülal Aşçı Toraman","doi":"10.4274/tpd.galenos.2024.03521","DOIUrl":"10.4274/tpd.galenos.2024.03521","url":null,"abstract":"<p><strong>Objective: </strong>In this study, it was aimed to examine the distribution of intestinal parasites detected in people who applied to the parasitology laboratory of Fırat University Faculty of Medicine between January 2018 and December 2021.</p><p><strong>Methods: </strong>Parasitological examination reports of a total of 24,432 patients who applied to the Parasitology Laboratory of Fırat University Faculty of Medicine between January 2018 and December 2021 were examined retrospectively for the presence of intestinal parasites.</p><p><strong>Results: </strong>A total of 24,432 (male: 12,887, 52.75%; female: 11,545, 47.25%) patients whose stool and cellophane tape samples were analyzed during the four-year period between January 2018 and December 2021 were included in the study. Intestinal parasites were found in 335 (1.4%) of the 24,432 patients examined. The most frequently detected parasite was <i>Giardia intestinalis</i> (n=149, 46.6%), followed by <i>Entamoeba coli</i> (n=123, 38.5%) and <i>Enterobius vermicularis</i> (n=28, 8.6%). When the distribution of parasite detection rates by years was examined, it was seen that the highest rate was in 2021 and the lowest rate was in 2019.</p><p><strong>Conclusion: </strong>Intestinal parasitic infections (IPE) are one of the most important public health problems in the world and in our country. Various factors such as the education level of the society, socio-economic status, infrastructure and climate affect the distribution of IPE. When we look at the distribution of parasites by years, it is 1.3% in 2018; 1.13% in 2019; 1.18% in 2020; In 2021, we found it to be 2.03%. We think that this increase in intestinal parasites is caused by the infrastructure and sheltering problems caused by the earthquake in our region.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Cerebral Hydatic Cyst Developed After Operation of Cardiac Hydatic Cyst: A Case Report. 心脏积水囊肿手术后出现多发性脑积水囊肿:病例报告
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2024.18480
İmren Mutlu, Ömer Ruşen Koyuncu, Yasemin Çakır
{"title":"Multiple Cerebral Hydatic Cyst Developed After Operation of Cardiac Hydatic Cyst: A Case Report.","authors":"İmren Mutlu, Ömer Ruşen Koyuncu, Yasemin Çakır","doi":"10.4274/tpd.galenos.2024.18480","DOIUrl":"10.4274/tpd.galenos.2024.18480","url":null,"abstract":"<p><p>Hydatid cyst is a zoonotic disease and is an important health problem, especially in developing countries. Hydatic cysts are typically observed in the liver and lungs. Cardiac and brain involvement are rare manifestations. Cardiac hydatic cysts are usually located in the left ventricle. Brain involvement is frequently seen as a primary cerebral cyst and is almost always solitary. However, secondary intracerebral cysts are also seen as a result of cardiac cysts rupturing into the left ventricle spontaneously or iatrogenically, and these are usually multiple. Herein, we report a case that has two rare clinical manifestations of hydatid cysts.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"62-65"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of Scabies Infestations in Stray Dogs in Bursa Province. 布尔萨省流浪狗疥疮感染的分布情况。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2023.79664
Betül Saygın, Ahmet Onur Girişgin, Suna Aslı Zengin, Levent Aydın
{"title":"Distribution of Scabies Infestations in Stray Dogs in Bursa Province.","authors":"Betül Saygın, Ahmet Onur Girişgin, Suna Aslı Zengin, Levent Aydın","doi":"10.4274/tpd.galenos.2023.79664","DOIUrl":"10.4274/tpd.galenos.2023.79664","url":null,"abstract":"<p><strong>Objective: </strong>Scabies infestation is a major parasitic disease affecting both human and animal health worldwide. This study aimed to determine the distribution of scabies infestation in stray dogs in Bursa province.</p><p><strong>Methods: </strong>The study material was obtained from stray dogs suspected of mange kept in a municipal shelter in Bursa between June 2020 and February 2022. Samples from stray dogs were examined in a laboratory, and dogs with scabies were determined.</p><p><strong>Results: </strong>During the study, samples were collected from 205 (115 males, 90 females) scabies-suspected stray dogs, 58 (28.29%) of which had scabies. <i>Demodex</i> spp. were detected in 35 of the positive dogs (60.34%) (<i>D. canis, D. injae</i>), 19 (32.76%) <i>Sarcoptes scabiei canis</i>, 2 (3.44%) mixed infestation (<i>Sarcoptes</i> and <i>Demodex</i>), and 2 (3.44%) <i>Otodectes cynotis</i> agents. It was determined that 32 (55.17%) of 58 scabies-positive dogs were male and 26 (44.83%) were female. The association of infestations with age, season, and sex has not been found to be statistically meaningful.</p><p><strong>Conclusion: </strong>This study identified scabies agents and their prevalence rate in stray dogs of Bursa province, Türkiye.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Dangerous Relationship: A Case of Imported Plasmodium falciparum and Salmonella Typhi Coinfection. 危险的关系:一例输入性恶性疟原虫和伤寒沙门氏菌合并感染病例。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2024.71463
Derya Tuna Ecer, Yener Özel, Oktay Yapıcı, Mehmet Ünlü
{"title":"A Dangerous Relationship: A Case of Imported <i>Plasmodium falciparum</i> and <i>Salmonella</i> Typhi Coinfection.","authors":"Derya Tuna Ecer, Yener Özel, Oktay Yapıcı, Mehmet Ünlü","doi":"10.4274/tpd.galenos.2024.71463","DOIUrl":"10.4274/tpd.galenos.2024.71463","url":null,"abstract":"<p><p>Malaria is a parasitic disease transmitted by the bite of female Anopheles mosquitoes. Although domestic malaria case notification in our country is not seen in World Health Organization records, cases originating from abroad are detected. Travelers to countries where malaria is endemic can become infected with the parasite. In our country, an average of 200-250 cases of malaria originating from abroad are reported every year. Approximately 75% of malaria cases of foreign origin detected in our country are <i>P. falciparum</i> malaria. Malaria and salmonellosis are infections especially seen in developing countries. Although malaria-<i>Salmonella</i> coinfection is rare, early diagnosis and treatment are important in terms of its high mortality rate. Preliminary information and initiation of chemoprophylaxis in travels to regions where the disease is endemic remain important in transmission. In this presentation, a case was examined following a business trip to Africa without any chemoprophylaxis, who applied to a local hospital upon symptoms and was diagnosed with <i>P. falciparum</i> and <i>Salmonella</i> Typhi coinfection but given incomplete treatment. After returning to our country, the patient applying to us with complaints of high fever, chills, nausea, diarrhea and abdominal pain and was discharged with ful recovery.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"58-61"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Anisakis simplex Global Research: A Bibliometric Analysis Study. 全球单纯疟原虫研究趋势:文献计量分析研究。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2024.94830
Mehmet Emin Aydemir, Selahattin Aydemir, Serap Kılıç Altun, Sevil Alkan
{"title":"Trends in <i>Anisakis simplex</i> Global Research: A Bibliometric Analysis Study.","authors":"Mehmet Emin Aydemir, Selahattin Aydemir, Serap Kılıç Altun, Sevil Alkan","doi":"10.4274/tpd.galenos.2024.94830","DOIUrl":"10.4274/tpd.galenos.2024.94830","url":null,"abstract":"<p><strong>Objective: </strong><i>Anisakis simplex</i> is a fish-borne zoonotic parasite. Although this parasite has been known since the 19<sup>th</sup> century, publications on anisakiasis have increased in recent years. Despite this, this subject has yet to be well studied by bibliometric analysis. This study was conducted to show the research points and trends of <i>A. simplex</i>.</p><p><strong>Methods: </strong>The Web of Science Core Collection (WoSCC) was mined for articles on <i>A. simplex</i>. The VOSviewer software visually evaluated countries, institutions, authors, references, and keywords in this field.</p><p><strong>Results: </strong>A total of 1362 publications were included in this bibliometric analysis. The included publications were published between 1970 and 2022 from 79 countries, mainly from Spain (n=456, 33.48%). The most prolific year was 2020 (n=74). The research area that attracted the most publications was parasitology (n=452), while the most productive author in this area was Cuellar C (n=53). <i>\"Anisakis simplex\"</i>, <i>\"Anisakis\"</i> and <i>\"anisakiasis\"</i> were the most used three keywords.</p><p><strong>Conclusion: </strong>The number of publications on anisakiasis has been increasing over time, suggesting that <i>A. simplex</i> is becoming an increasingly important disease worldwide. Research cooperation should be established between researchers from developed and developing countries to determine effective control strategies for anisakiasis.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Head Lice and Intestinal Parasites in Primary and Secondary School in Sivas. 锡瓦斯中小学头虱和肠道寄生虫调查。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2023.04796
Sevinç Çamdalı, Murat Teke, Mehmet Tugay Eren, Eren Yenidünya, Elif Akyol, Serpil Değerli
{"title":"Investigation of Head Lice and Intestinal Parasites in Primary and Secondary School in Sivas.","authors":"Sevinç Çamdalı, Murat Teke, Mehmet Tugay Eren, Eren Yenidünya, Elif Akyol, Serpil Değerli","doi":"10.4274/tpd.galenos.2023.04796","DOIUrl":"10.4274/tpd.galenos.2023.04796","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to investigate the prevalence of intestinal parasites and head lice in primary school-aged children and to determine a possible relationship between the co-occurrence of ecto-endoparasites.</p><p><strong>Methods: </strong>The study were conducted in three schools in the center of Sivas: Sivas Karşıyaka Primary School, Kılavuz İMKB Primary School, and Karşıyaka 27 June Middle School. The presence of head lice and intestinal parasites was investigated in a total of 563 children aged 6 to 17, with 294 girls and 269 boys. Classroom teachers and students were provided with information about intestinal parasites, head lice, and methods of transmission and prevention, and a questionnaire was administered. During the head lice examination, students were inspected with a comb, and samples with nits were examined under a microscope in the laboratory. Cellophane tape and stool samples obtained from the participants were examined on the same day using the native-lugol, flotation, and trichrome staining methods under a light microscope (x10, x40, x100).</p><p><strong>Results: </strong>Five hundred sixty-three children were evaluated for head lice and 15 (2.6%) were found to be positive. During the examination, only nits were found in 11 students (1.9%), and both adult lice and nymphs were seen in 4 students (0.7%). Head lice were found positive in 2 out of 269 boys (0.7%), while 13 out of 294 girls (4.2%) positive (p<0.05). As a result of stool examination in children, <i>Entamoeba coli</i> was found in 11 (1.95%), <i>Giardia intestinalis</i> in 4 (0.71%), <i>Blastocystis</i> sp. in 14 (2.48%), <i>Enterobius vermicularis</i> in 8 (1.42%) and <i>Taenia</i> spp. in 2 (0.35%). Head lice infestation and <i>Taenia</i> spp. were found to coexist in 2 (0.35%) children.</p><p><strong>Conclusion: </strong>In conclusion, although there has been a noticeable decrease in head lice and intestinal parasites among primary school-aged children in Sivas province, these conditions are still present, as evidenced by previous studies conducted in our region.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"32-38"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Sensitivity of Rapid Diagnosis Tests in Patients with Suspected Malaria 疑似疟疾患者的快速诊断测试灵敏度调查
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2024.38358
Gülnaz Çulha, Yusuf Önlen, Mehmet Çabalak, Tuğba Kaya, Burcu Küçükeser
{"title":"Investigation of Sensitivity of Rapid Diagnosis Tests in Patients with Suspected Malaria","authors":"Gülnaz Çulha, Yusuf Önlen, Mehmet Çabalak, Tuğba Kaya, Burcu Küçükeser","doi":"10.4274/tpd.galenos.2024.38358","DOIUrl":"10.4274/tpd.galenos.2024.38358","url":null,"abstract":"<p><strong>Objective: </strong>Malaria has been eradicated in Türkiye as of 2010, but there are imported cases. In this study, we aimed to compare the diagnostic value of two rapid tests; SD Bioline Malaria Ag Pf/Pan (SD-Pf/Pan) and SD Bioline Malaria Ag Pf/Pv (SD-Pf/Pv) with microscopy and real time-polymerase chain reaction (RT-PCR).</p><p><strong>Methods: </strong>Blood samples were taken from all participants. Thick drop smears were prepared. Thick drop smears were examined for malaria positive/negative distinction under the light microscopy. Then, two rapid diagnostic tests (SD-Pf/Pan and SD-Pf/Pv) were performed. After DNA extraction from blood samples, RT-PCR was typed. The data were evaluated with SPSS 21 program of statistics.</p><p><strong>Results: </strong>A total of 30 cases out of 66 suspected malaria cases were detected as positive with microscopy and RT-PCR. Twenty-seven patients were found positive with both SD-Pf/Pan and SD-Pf/Pv tests. Based on the microscopic results as a reference method, SD-Pf/Pan and SD-Pf/Pv rapid diagnostic tests had a 90% sensitivity, 100% specificity, 100% positive predictive value (PPV), and 92.86% negative predictive value (NPV). Based on the RT-PCR results as a reference method, for detection of <i>P. falciparum</i>, both tests had a 95.65% sensitivity, 100% specificity, 100% PPV, and 88.89% NPV. Moreover, while SD-Pf/Pv had a sensitivity, specificity, PPV, and NPV of 100% in detection of <i>P. vivax</i>; SD-Pf/Pan has a 77.78% sensitivity of, 61.90% specificity of, 46.67% PPV, and 86.67% NPV SD-Pf/Pan for detection of PAN.</p><p><strong>Conclusion: </strong>As a result, high sensitivity and specificity were detected in both kits in the diagnosis of malaria infections caused by <i>P. falciparum</i> and <i>P. vivax</i>. Rapid diagnostic tests can be used safely in diagnosis however the diagnosis should be supported by microscopy and RT-PCR methods when they are applicable.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Trichomonas vaginalis Activity of Marine Ascidians (Tunicates; Ascidiacea) from the Bushehr Province, Iran 伊朗布什尔省海洋无脊椎动物(鳞目;无脊椎动物科)的抗阴道毛滴虫活性。
Turkiye parazitolojii dergisi Pub Date : 2024-03-05 DOI: 10.4274/tpd.galenos.2023.96658
Hamideh Malekhayati, Afshar Bargahi, Soleiman Khorami, Mohsen Khataminejad, Moradali Fouladvand
{"title":"Anti-<i>Trichomonas vaginalis</i> Activity of Marine Ascidians (Tunicates; Ascidiacea) from the Bushehr Province, Iran","authors":"Hamideh Malekhayati, Afshar Bargahi, Soleiman Khorami, Mohsen Khataminejad, Moradali Fouladvand","doi":"10.4274/tpd.galenos.2023.96658","DOIUrl":"10.4274/tpd.galenos.2023.96658","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the current research is to evaluate the antiparasite effects of compounds isolated from marine ascidian tunicates on <i>Trichomonas vaginalis</i>.</p><p><strong>Methods: </strong>Ascidian tunicates after collection were cut into small pieces, freeze-dried, and powdered. The resulting material was subjected to extraction in double-distilled water, ethanol, n-hexane, and dichloromethane. To fractionate the extracts and identify the most bioactive compound, silica gel column chromatography and GC-M/S analysis were used.</p><p><strong>Results: </strong>Fraction 18 of silica gel column chromatography of ethanol extract was the most effective against <i>T. vaginalis</i>. The respective IC<sub>50</sub>, CC<sub>50</sub>, and SI values for fraction 18 were 28.62 μg/mL, ˃800 μg/mL, and ˃27.95. GC-M/S analysis of this fraction identified a major phenolic compound (2, 4-bis (1, 1-dimethyl ethyl), whose toxicity against vero cells was only 10.15%.</p><p><strong>Conclusion: </strong>The ethanolic fraction containing phenol-2,4-bis (1,1-dimethylethyl), which has a potent lethality effect on <i>T. vaginalis</i>, may be considered as an antiparasite drug candidate.</p>","PeriodicalId":34974,"journal":{"name":"Turkiye parazitolojii dergisi","volume":"48 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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