Review of Diabetic Studies最新文献_第3页

Vitamin D Deficiency as a Possible Cause of Type 1 Diabetes in Children and Adolescents up to 15 Years Old: A Systematic Review. 维生素D缺乏是15岁以下儿童和青少年1型糖尿病的可能原因:一项系统综述。

Review of Diabetic Studies Pub Date : 2022-06-30 DOI: 10.1900/RDS.2022.18.58

Maria Daskalopoulou, Magdalini Pylli, Konstantinos Giannakou

{"title":"Vitamin D Deficiency as a Possible Cause of Type 1 Diabetes in Children and Adolescents up to 15 Years Old: A Systematic Review.","authors":"Maria Daskalopoulou, Magdalini Pylli, Konstantinos Giannakou","doi":"10.1900/RDS.2022.18.58","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.58","url":null,"abstract":"OBJECTIVE: To evaluate vitamin D ((25OH)D levels) deficiency as a possible cause in the development of DT1 in children and adolescents aged 0-15. METHODS: We searched PubMed/ Medline, EBSCO, and Cochrane Library to identify potentially eligible articles that examine whether low serum 25(OH)D levels are associated with subsequent development of DT1. All type of research designs, including randomized and non-randomized controlled trials, prospective and retrospective cohort studies, case- control and cross-sectional studies with subjects aged ≤15 years old were consider for inclusion. RESULTS: Seven original studies met the entry criteria. Most of these studies found up to 50% lower levels of vitamin D in children with DT1 compared to control group and a significant positive association between vitamin D levels and of the risk of developing DT1. Results of quality assessment demonstrated moderate to high quality of all the studies included. CONCLUSIONS: Vitamin D deficiency may be a possible cause in the development of DT1 in the early years of life and particularly in children with genetic predisposition, whilst the deficiency of vitamin D is a very common occurrence in patients with DT1. Further long-term studies on children are required to determine the role of vitamin D on DT1.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9254295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asian Best Practices for Care of Diabetes in Elderly (ABCDE). 亚洲老年糖尿病护理最佳实践(ABCDE)。

Review of Diabetic Studies Pub Date : 2022-06-30 DOI: 10.1900/RDS.2022.18.100

Sanjay Kalra, Minakshi Dhar, Faria Afsana, Pankaj Aggarwal, Than Than Aye, Ganapathy Bantwal, Manash Barua, Saptarshi Bhattacharya, Ashok Kumar Das, Sambit Das, Arundhati Dasgupta, Guruprasad Dhakal, Atul Dhingra, Fatemeh Esfahanian, Sharvil Gadve, Jubbin Jacob, Nitin Kapoor, Ali Latheef, Yovan Mahadeb, Robin Maskey, Wali Naseri, Jeya Ratnasingam, Abbas Raza, Banshi Saboo, Rakesh Sahay, Mona Shah, Shehla Shaikh, S K Sharma, Dina Shrestha, Noel Somasundaram, Mangesh Tiwaskar, Apurva Jawdekar

{"title":"Asian Best Practices for Care of Diabetes in Elderly (ABCDE).","authors":"Sanjay Kalra, Minakshi Dhar, Faria Afsana, Pankaj Aggarwal, Than Than Aye, Ganapathy Bantwal, Manash Barua, Saptarshi Bhattacharya, Ashok Kumar Das, Sambit Das, Arundhati Dasgupta, Guruprasad Dhakal, Atul Dhingra, Fatemeh Esfahanian, Sharvil Gadve, Jubbin Jacob, Nitin Kapoor, Ali Latheef, Yovan Mahadeb, Robin Maskey, Wali Naseri, Jeya Ratnasingam, Abbas Raza, Banshi Saboo, Rakesh Sahay, Mona Shah, Shehla Shaikh, S K Sharma, Dina Shrestha, Noel Somasundaram, Mangesh Tiwaskar, Apurva Jawdekar","doi":"10.1900/RDS.2022.18.100","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.100","url":null,"abstract":"The elderly population with diabetes is diverse with the majority experiencing a decline in physical and mental capabilities, impacting the entire diabetes management process. Therefore, a need for geriatric-specific guidelines, especially for the Asian population, was identified and subsequently developed by an expert panel across government and private institutions from several Asian countries. The panel considered clinical evidence (landmark trials, position papers, expert opinions), recommendations from several important societies along with their decades of clinical experience and expertise, while meticulously devising thorough geriatric-specific tailored management strategies. The creation of the ABCDE best practices document underscores and explores the gaps and challenges and determines optimal methods for diabetes management of the elderly population in the Asian region.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Diagnostic Capabilities for Complications of Bacterial Infection in Diabetic Patients. 糖尿病患者细菌感染并发症诊断能力的发展。

Review of Diabetic Studies Pub Date : 2022-06-30 DOI: 10.1900/RDS.2022.18.135

Samiah Hamad S Al-Mijalli, Ashwag Y Shami, Rasha A Al-Salem, Nawaf M Alnafisi

{"title":"Development of Diagnostic Capabilities for Complications of Bacterial Infection in Diabetic Patients.","authors":"Samiah Hamad S Al-Mijalli, Ashwag Y Shami, Rasha A Al-Salem, Nawaf M Alnafisi","doi":"10.1900/RDS.2022.18.135","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.135","url":null,"abstract":"OBJECTIVE: Our objective was to assess the pattern of urine infections, the most common pathogen, and their susceptibility pattern to antibiotics among Saudi diabetic patients. METHODS: We performed a year-long cross-sectional study from January 2018 to January 2019 at KAAU Hospital in Riyadh, KSA. We cultured the urine specimens obtained from diabetic patients based on optimal aerobic and anaerobic microbiological methods. By adopting standard microbiological methods, we identified the bacterial isolates. We also followed the guidelines of the Clinical and Laboratory Standards Institute (CLSI) to do antibiotic susceptibility testing. RESULTS: A total of 100 isolates were evaluated, and a total of 22 organisms were isolated. The majority were multidrug-resistant organisms. Streptococcus haemolyticus was the most frequent organism and rated (15%). It was followed by Staphylococcus hominis (11%), Pseudomonas aeruginosa (9%), Enterococcus faecalis (9%), Enterococcus fiseum (7%), Escherichia coli (7%), Staphylococcus aureus (7%), Staphylococcus lantus (5%) and Klebsiella pneumoniae (5%). We also found multi-microbial infections. Most of the organisms were susceptible to tigecycline, gentamycin, and nitrofurantoin, rating (88%), (84%) and (78%), respectively. CONCLUSIONS: Our study revealed that a wide range of pathogens affects the diabetes patients. Staphylococcus haemolyticus is the most prevalent pathogen. We observed considerable antimicrobial resistance. Tigecycline had a wide sensitivity spectrum and was effective against most of the bacteria. Thus, it can be used as an empirical antibiotic.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9254296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of Aronia melanocarpa on Cardiometabolic Diseases: A Systematic Review of Quasi-Design Studies and Randomized Controlled Trials. 黑桫椤对心脏代谢疾病的影响:准设计研究和随机对照试验的系统综述。

Review of Diabetic Studies Pub Date : 2022-06-30 DOI: 10.1900/RDS.2022.18.76

Christine B Christiansen, Fredrik B Mellbye, Kjeld Hermansen, Per B Jeppesen, Søren Gregersen

{"title":"Effects of Aronia melanocarpa on Cardiometabolic Diseases: A Systematic Review of Quasi-Design Studies and Randomized Controlled Trials.","authors":"Christine B Christiansen, Fredrik B Mellbye, Kjeld Hermansen, Per B Jeppesen, Søren Gregersen","doi":"10.1900/RDS.2022.18.76","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.76","url":null,"abstract":"OBJECTIVES: Aronia melanocarpa (Aronia) is a shrub with small berries, chokeberries. Chokeberries are claimed to possess health benefits due to a high content of polyphenols. Aronia is known to be extremely antioxidant; however, evidence for its health benefits is not established. This review gives an overview of the impact of Aronia on cardiometabolic risk factors and diseases. METHODS: Seventeen studies on cardiometabolic risk factors and diseases were identified through a systematic search on PubMed, Embase, and Cochrane. Inclusion criteria were studies with Aronia as intervention, performed in individuals with cardiometabolic disease or risk factors, e. g., type 2 diabetes (T2D), cardiovascular disease, hypertension, dyslipidaemia, impaired glucose tolerance, overweight, central obesity and smoking. Four of these studies were applicable for a quantitative analysis. RESULTS: Aronia did not influence body weight, circulating triglycerides, total cholesterol, high-density lipoprotein (HDL) cholesterol, or blood pressure. The quantitative analysis revealed a mean reduction in blood glucose of 0.44 mmol/l (P=0.0001) in the treatment group compared with the control group suggesting that Aronia treatment may have a beneficial impact on blood glucose. In addition, treatment durations of 6 weeks to 3 months tended to decrease low-density lipoprotein (LDL) cholesterol, while shorter treatment durations had no effect on LDL cholesterol. The quantitative analysis did not provide data on long-term effects of Aronia on lipids. CONCLUSIONS: More long-term high-quality randomized controlled studies are needed to clarify if dietary supplementation with Aronia has beneficial effects on cardiometabolic diseases.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9201511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

1,5-Anhydroglucitol as a Marker of Acute Hyperglycemia in Cardiovascular Events. 1,5-无水葡萄糖醇作为心血管事件中急性高血糖的标志物。

Review of Diabetic Studies Pub Date : 2022-06-30 DOI: 10.1900/RDS.2022.18.68

Marta Migała, Justyna Chałubińska-Fendler, Marzenna Zielińska

{"title":"1,5-Anhydroglucitol as a Marker of Acute Hyperglycemia in Cardiovascular Events.","authors":"Marta Migała, Justyna Chałubińska-Fendler, Marzenna Zielińska","doi":"10.1900/RDS.2022.18.68","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.68","url":null,"abstract":"1,5-anhydroglucitol (1,5-AG) is a biomarker of acute hyperglycemia in diabetology and also in cardiodiabetology. It is used to monitor fluctuating glucose levels. 1,5-AG is a monosaccharide that is biochemically similar to D-glucose and originates from the nutrition. The presence of 1,5-AG in blood and tissue is nearly constant due to reabsorption in the renal proximal tubule. In acute hyperglycemia, renal reabsorption is inhibited by glucose and 1,5- AG is excreted in the urine, while its serum level decreases rapidly. 1,5-AG reflects glucose excursions over 1-3 days to 2 weeks. In this regard, low levels of serum 1,5-AG can be a clinical marker of short- term glycemic derangements such as postprandial hyperglycemia, which is an important risk factor for the pathogenesis of coronary artery disease (CAD) as low levels of 1,5-AG reflect severe plaque calcification in CAD and correlate with high-density lipoprotein cholesterol (HDL-C) levels. For these reasons, 1,5-AG may also be a marker for atherosclerosis; in fact an even better marker than HbA1c or fructosamine which are normally used. 1,5-AG may also be a predictor of cardiovascular disease, left ventricular dysfunction after acute coronary syndrome (ACS), and mortality after ACS. This articles reviews the current knowledge on 1,5-AG related to its use as predictor for cardiovascular events.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9254293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Abnormal High-sensitivity C-reactive Protein is Associated with an Increased Risk of Cardiovascular Disease and Renal Dysfunction among Patients Diagnosed with Type 2 Diabetes Mellitus in Palestine 在巴勒斯坦诊断为2型糖尿病的患者中，异常的高敏c反应蛋白与心血管疾病和肾功能障碍的风险增加有关

Review of Diabetic Studies Pub Date : 2022-03-09 DOI: 10.1900/RDS.2022.18.27

M. Khattab, Moyad Shahwan, Nageeb Hassan, A. Jairoun

{"title":"Abnormal High-sensitivity C-reactive Protein is Associated with an Increased Risk of Cardiovascular Disease and Renal Dysfunction among Patients Diagnosed with Type 2 Diabetes Mellitus in Palestine","authors":"M. Khattab, Moyad Shahwan, Nageeb Hassan, A. Jairoun","doi":"10.1900/RDS.2022.18.27","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.27","url":null,"abstract":"OBJECTIVE In this study, we aimed to evaluate the prevalence of high sensitivity C-reactive protein (hsCRP) as an inflammatory mediator and its association with renal function and other biochemical markers in patients with type 2 diabetes mellitus. METHODS We carried out a cross-sectional study at private healthcare center. We included 453 patients (48.6% males and 51.4% females) with type 2 diabetes mellitus. We obtained sociodemographic, clinical, and laboratory data from patient medical records. We carried out statistical analysis to ascertain associations between parameters. RESULTS The overall risk of cardiovascular disease (hsCRP > 1 mg/L) among the study participants was 27.2%. Age, gender, body mass index, fasting blood glucose and serum creatinine were significantly associated with risk of cardiovascular disease (hsCRP > 1 mg/L) whereas estimated glomerular filtration rate, vitamin B12, calcium, sodium and metformin users were negatively associated with the hsCRP. CONCLUSIONS We found a significant positive association of elevated level of C-reactive protein with type 2 diabetes mellitus. Moreover, additional to increased cardiovascular disease risk, hsCRP also seems to be a major inflammatory risk marker indicating renal function loss.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78744757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effect of Early Time-Restricted Feeding on Glycemic Profile in Adults: A Systematic Review of Interventional Studies 早期限时喂养对成人血糖分布的影响:介入研究的系统回顾

Review of Diabetic Studies Pub Date : 2022-03-09 DOI: 10.1900/RDS.2022.18.10

Demetrios Bitsanis, K. Giannakou, Elena Hadjimbei, S. Chrysostomou

{"title":"The Effect of Early Time-Restricted Feeding on Glycemic Profile in Adults: A Systematic Review of Interventional Studies","authors":"Demetrios Bitsanis, K. Giannakou, Elena Hadjimbei, S. Chrysostomou","doi":"10.1900/RDS.2022.18.10","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.10","url":null,"abstract":"BACKGROUND Early time-restricted feeding (eTRF) is a new dietary strategy, involving extended fasting (>14h) from midafternoon onwards with or without calorie restriction. Most of the published studies indicate controversial effects on several glycemic markers. AIM To evaluate the effect of non-calorie restricted eTRF on the glycemic profile of adults. METHOD this systematic review was designed according to PRISMA guidelines. Pubmed/ Medline, the Cochrane library and EBSCO electronic databases were systematically searched for eligible clinical trials. Studies with eTRF or with daily fasting regimens that presented all the characteristics of eTRF were selected and compared with regular diet schedules or delayed time-restricted feeding. Blood glucose and insulin markers were extracted from each study as the main outcome measures. RESULTS Five articles including 67 adult subjects in total were selected. The period of intervention varied between 3 days to 5 weeks. Three of the included studies were diet- controlled for weight maintenance, whereas the other two studies allowed for free living. Quality assessment identified two studies of low and three studies of high risk of bias. two studies showed clear positive effects of eTRF on both glucose and insulin markers, including fasting glucose levels, muscle glucose intake, glucose iAUC responses insulin levels, and insulin resistance (p<0.05). Two other studies showed beneficial effects on glucose markers only (fasting glucose, 24h mean glucose levels, and iAUC responses, p<0.05) and the fifth study showed positive effects on insulin markers only (insulin resistance, p<0.05). CONCLUSIONS eTRF seems to have positive effects on the glycemic profile mainly in healthy individuals with normal BMI. However, other factors should also be taken into account to address overweight, obese, and prediabetic individuals. Further research is required to clarify better the effectiveness of eTRF among individuals with different characteristics.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75406556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Factors Affecting Mortality of Critical Limb Ischemia 1 Year after Endovascular Revascularization in Patients with Type 2 Diabetes Mellitus 2型糖尿病患者血管内血管重建术后1年重症肢体缺血死亡率的影响因素

Review of Diabetic Studies Pub Date : 2022-03-09 DOI: 10.1900/RDS.2022.18.20

E. Yunir, Beta Agustia Wisman, Dono Antono, A. Mansjoer, Angela Sarumpaet, Eni Iswati, Martha Rosana, D. Tahapary, T. Tarigan, P. Soewondo

{"title":"Factors Affecting Mortality of Critical Limb Ischemia 1 Year after Endovascular Revascularization in Patients with Type 2 Diabetes Mellitus","authors":"E. Yunir, Beta Agustia Wisman, Dono Antono, A. Mansjoer, Angela Sarumpaet, Eni Iswati, Martha Rosana, D. Tahapary, T. Tarigan, P. Soewondo","doi":"10.1900/RDS.2022.18.20","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.20","url":null,"abstract":"BACKGROUND Chronic limb ischemia (CLI) is strongly associated with increased mortality in diabetes patients. OBJECTIVE The aim of this study was to evaluate factors affecting mortality within 1 year after endovascular revascularization in CLI patients. METHODS This retrospective cohort study was based on medical records from the Integrated Cardiovascular Centre of Dr. Cipto Mangunkusumo National General Hospital, a tertiary care hospital in Jakarta, Indonesia. The study included 199 CLI patients with type 2 diabetes mellitus (T2DM) who underwent endovascular revascularization from January 2008 to June 2018. The patients were followed up for 1 year after endovascular revascularization. Kaplan-Meier and Cox proportional hazard analysis was used to analyze the data. RESULTS 1-year survival probability was 58.8%. Cox proportional hazard analysis showed that duration of diabetes (HR 3.52; 95% CI 1.34-9.22), anemia (HR 2.59; 95% CI 1.47-4.56), and smoking (HR 2.49; 95% CI 1.46-4.27) were significantly associated with mortality within 1 year after endovascular revascularization. CONCLUSIONS In T2DM patients with CLI, duration of diabetes, anemia and smoking were associated with a higher risk of mortality within 1 year post endovascular revascularization","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81666618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Review of Diabetic Studies Pub Date : 2022-03-09 DOI: 10.1900/RDS.2022.18.34

J. Natarajan, S. Mokoboto-Zwane

{"title":"Health-related Quality of Life and Domain-specific Associated Factors among Patients with Type2 Diabetes Mellitus in South India","authors":"J. Natarajan, S. Mokoboto-Zwane","doi":"10.1900/RDS.2022.18.34","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.34","url":null,"abstract":"OBJECTIVE Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that has a major impact on health-related quality of life (HRQOL). The economic burden of the disease, along with its complications, negatively impact the individual, family, and society of Indian diabetic patients. This study explored the perception of the diabetic HRQOL of South Indian type2diabetic patients. METHODS This study was a cross-sectional descriptive quantitative study conducted in a tertiary care hospital in Chennai, Tamil Nadu, South India. Using the simple random sampling technique, we collected data from 352 T2DM patients aged ≥ 30 years of age who were diagnosed for a minimum of one year. Data collection occurred from June to August 2017. Data were analysed using IBM SPSS, Version 22. RESULTS Overall, 90% of patients with T2DM perceived poor HRQOL. The total and the domain- specific mean scores of HRQOL were high indicating poor HRQOL in energy mobility, diabetes control, anxiety and worry, social burden, and sexual functioning domains. Being female, increasing age, lower education levels, lower family income, and uncontrolled fasting blood glucose levels predicted poor HRQOL of patients with T2DM. CONCLUSIONS T2DM impacted the HRQOL in all measured domains of participants. A patient-centred approach to diabetes management can be incorporated to improve or enhance the health-related quality of patients’ lives. Improved HRQOL also may lead to fewer hospitalizations, and hence, reduce healthcare costs.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89666195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effects of Anthocyanin-rich Berries on the Risk of Metabolic Syndrome: A Systematic Review and Meta-analysis 富含花青素的浆果对代谢综合征风险的影响:系统综述和荟萃分析

Review of Diabetic Studies Pub Date : 2022-03-09 DOI: 10.1900/RDS.2022.18.42

Mikkel Roulund Wilken, M. Lambert, C. Christensen, P. Jeppesen

{"title":"Effects of Anthocyanin-rich Berries on the Risk of Metabolic Syndrome: A Systematic Review and Meta-analysis","authors":"Mikkel Roulund Wilken, M. Lambert, C. Christensen, P. Jeppesen","doi":"10.1900/RDS.2022.18.42","DOIUrl":"https://doi.org/10.1900/RDS.2022.18.42","url":null,"abstract":"OBJECTIVE Metabolic syndrome (MetS) can lead to fatal complications, including cardiovascular disease. Emerging evidence suggests has emerged that increased fruit and vegetable intake and decreased intake of saturated fats, simple sugars, and processed foods can improve cardiovascular health. Anthocyanins (color pigments) have anti-inflammatory and antioxidant capacities but are of low bioavailability. In this systematic review and metaanalysis, we investigate the possible beneficial effects of the intake of berries high in anthocyanins on MetS risk factors. We also investigate the influences of high-density lipoprotein (HDL), low- density lipoprotein (LDL), triglycerides (TG), and total cholesterol (TC). METHODS We identified 2,274 articles from PUBMED and EMBASE following a search input designed to include studies of interest of these, 21 met inclusion criteria. RESULTS The studies showed an overall reduction in low-density lipoprotein (p=0.04). Increases in HDL were found with cranberry and freeze-dried berry intake during a 4-6-week intervention. No statistically significant findings were detected for fasting glucose, Hb1Ac, insulin levels, blood pressure, oxidized LDL (OX-LDL), BMI, and overall HDL. CONCLUSIONS We conclude from this systematic review and meta-analysis that increased berry intake improves MetS key risk factors and reduces the risk of cardiovascular disease. Pronounced effects were apparent for concentrated berry products, such as freeze-dried strawberries.","PeriodicalId":34965,"journal":{"name":"Review of Diabetic Studies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80087887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4