{"title":"METFORMIN IS LINKED TO REDUCED MORTALITY IN TYPE 2 DIABETES WITH COMORBID CKD AND CHF: A SYSTEMATIC REVIEW","authors":"Chrysman Andreria Hatulely","doi":"10.53555/nnmhs.v9i8.1808","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1808","url":null,"abstract":"Introduction: Due to DM diagnosis criteria, determining its incidence is difficult. Diabetes affects 10.2 million Americans. Due to conflicting data on mortality and antihyperglycemic therapy benefits, managing hyperglycemia in type 2 diabetes mellitus (T2DM) patients at risk of cardiovascular problems is difficult. \u0000The aim: This article showed about metformin is Linked to reduced mortality in type 2 diabetes with comorbid chronic kidney disease (CKD) and congestive heart failure (CHF). \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 85 articles, whereas the results of our search on SagePub brought up 57 articles. The results of the search conducted for the last year of 2013 yielded a total 34 articles for PubMed and 21 articles for SagePub. In the end, we compiled a total of 19 papers, 13 of which came from PubMed and seven of which came from SagePub. We included five research that met the criteria. \u0000Conclusion: Metformin use was found to be related with a reduced risk of death from any cause as well as progression toward ESRD in patients with CKD and CHF in the current investigation.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132838334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DIABETES MEDICATIONS AS MONOTHERAPY OR METFORMIN - BASED COMBINATION THERAPY FOR TYPE 2 DIABETES : A SYSTEMATIC REVIEW","authors":"Chrysman Andreria Hatulely","doi":"10.53555/nnmhs.v9i8.1810","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1810","url":null,"abstract":"Introduction: Early combination therapy may reduce glucotoxicity. This method may improve insulin sensitivity and preserve bulk and function.10 Early combination therapy with several antihypertensive agents may increase costs and patient compliance due to the number of pills, but a fixed-dose medication combination can help.\u0000The aim: This article compared monotherapy or metformin - based combination therapy for type 2 diabetes medications\u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.\u0000 \u0000Result: In the PubMed database, the results of our search brought up 88 articles, whereas the results of our search on SagePub brought up 56 articles. The results of the search conducted for the last year of 2013 yielded a total 42 articles for PubMed and 31 articles for SagePub. In the end, we compiled a total of 11 papers, 7 of which came from PubMed and four of which came from SagePub. We included three research that met the criteria.\u0000 \u0000Conclusion: Initiation of the AHA combination of metformin and other drugs may provide better results in diabetes control. In addition, the combination of two and three drugs did not show significantly different results.\u0000 ","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124541538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BEHAVIORAL PROGRAMS FOR TYPE 2 DIABETES MELITUS: A SYSTEMATIC REVIEW","authors":"Chrysman Andreria Hatulely","doi":"10.53555/nnmhs.v9i8.1805","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1805","url":null,"abstract":"Introduction: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is possible that behavioral programs can improve outcomes for people living with type 2 diabetes mellitus; however, there is a huge variety of behavioral interventions to choose from, and it is unclear how to maximize the efficacy of these programs. \u0000The aim: This article discusses osteosynthesis in patients with femoral neck fractures. \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 655 articles, whereas the results of our search on SagePub brought up 254 articles. The results of the search conducted for the last year of 2013 yielded a total 192 articles for PubMed and 89 articles for SagePub. In the end, we compiled a total of 33 papers, 21 of which came from PubMed and 12 of which came from SagePub. We included seven research that met the criteria. \u0000Conclusion: Non-pharmacological interventions that can be carried out are complementary therapies such as controlling eating patterns, doing relaxation and regular physical activity. Exercise is a strong stimulus to increase glucose input (glucose uptake) into muscle cells.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134253939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFICIACY OF MINIMALLY INVASIVE SURGERY ON HALLUX VALGUS : A SYSTEMATIC REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1798","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1798","url":null,"abstract":"Introduction: The terms \"Hallux valgus\" or \"hallux abducto-valgus\" are the medical terms most commonly used in relation to a bunion anomaly. These deformities can result from foot or joint abnormalities, but the most common cause is wearing too-small or too-large shoes. High heels cause the body to bend forward, which puts pressure on the toes. The type of surgery depends on the bones involved, their angular connection, the joint injury, and other deformities. \u0000The aim: This article describe about efficiacy of minimally invasive surgery on hallux valgus. \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 89 articles, whereas the results of our search on SagePub brought up 62 articles. The results of the search conducted for the last year of 2013 yielded a total 33 articles for PubMed and 17 articles for SagePub. In the end, we compiled a total of 19 papers, 12 of which came from PubMed and seven of which came from SagePub. We included seven research that met the criteria. \u0000Conclusion: MIS measures for HV surgery can be considered effective with a reoperation rate of less than 20%. Both the radiological and clinical outcome of the minimally invasive osteotomy and the open method are on par with one another.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128806463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OSTEOSYNTHESIS OF FRACTURES NECK FEMUR: A SYSTEMATIC REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1803","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1803","url":null,"abstract":"Introduction: US hip fractures exceed 250,000 each year. Femoral neck and intertrochanteric fractures are equally diagnosed. This number will double by 2050. Cannulated screws, hip screw systems, proximal femur plates, and cephalomedullary nails can treat femoral neck fractures. These procedures are evaluated for biomechanical stability. \u0000 \u0000The aim: This article discusses osteosynthesis in patients with femoral neck fractures.\u0000 \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.\u0000 \u0000Result: In the PubMed database, the results of our search brought up 123 articles, whereas the results of our search on SagePub brought up 72 articles. The results of the search conducted for the last year of 2013 yielded a total 75 articles for PubMed and 16 articles for SagePub. In the end, we compiled a total of 24 papers, 17 of which came from PubMed and seven of which came from SagePub. We included five research that met the criteria.\u0000 \u0000 ","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125560520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ARTICULAR CARTILAGE REGENERATION : A SYSTEMATIC REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1797","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1797","url":null,"abstract":"Articular cartilage is a highly specialised type of connective tissue found in bones-joints. Its primary function is to provide a smooth, lubricated surface for movement and to reduce the coefficient of friction to facilitate movement. Regenerative medicine has been developed in recent years as an alternative to conventional surgery. The objective is to create a new tissue that is as similar as feasible to the existing cartilage. Due to the close relationship between tissue structure and composition and function, it is believed that the capacity to reconstruct structure is essential for regeneration. Regenerative medicine has become one of the most fascinating areas of biotechnology through the use of cell and gene therapy and tissue engineering. This has given researchers, physicians, and patients a great deal of optimism. The primary objective of advances in this field is to heal damaged tissue, not to supplant it with an external device. In the future, grafts and artificial prostheses may not be necessary.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134205717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OVERVIEW OF PAEDIATRIC BONE AND JOINT : A SYSTEMATIC REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1799","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1799","url":null,"abstract":"Mercer Rang well observed, \"Children are not young adults.\" Children and adults have different skeleton physiology and morphology. Depending on bone growth and remodelling, skeletal conditions should be treated differently. Because bone growth and modelling differ. Children's bones are more flexible than those of adults, so they can move more before they break. People often use the word \"plastic deformation\" to describe a condition in which the bone changes shape but does not break. Sometimes, the bone might just bend, causing a type of break called a torus fracture. Adults don't have these patterns because their bones are much less flexible and resistant to bending at angles than those of a growing skeleton. When two bones touch, they make a joint. Groups of joints can be made based on how they look or how they work. Functional classification is based on how much movement is allowed, while histological classification is based on the type of connective tissue that makes up most of the body. The mesoderm gives rise to joints, which are made up of bones and connective tissue. Bones can form either directly or indirectly through endochondral ossification or intramembranous ossification. The blood supply and nerve supply to each joint follow different rhythms.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134534873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HIP FRACTURES AND VITAMIN D: A SYSTEMATIC REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1800","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1800","url":null,"abstract":"Introduction: Hip fractures are among the most common types of fractures that patients report with to emergency departments and orthopaedic trauma teams. Study showed association vitamin D and bone intensity. \u0000The aim: This article discusses association about hip fractures and vitamin D. \u0000Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2013 and 2023 were taken into account. Several different online reference sources, like Pubmed and SagePub, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done. \u0000Result: In the PubMed database, the results of our search brought up 218 articles, whereas the results of our search on SagePub brought up 109 articles. The results of the search conducted for the last year of 2013 yielded a total 88 articles for PubMed and 27 articles for SagePub. In the end, we compiled a total of 32 papers, 23 of which came from PubMed and nine of which came from SagePub. We included seven research that met the criteria. \u0000Conclusion: Research consistently shows a link between vitamin D and bone strength. This is related to the incidence of hip fractures.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133579641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DIAGNOSIS AND TREATMENT SPONDYLODISCITIS : THE LITERATURE REVIEW","authors":"Dhanang Susilo","doi":"10.53555/nnmhs.v9i8.1796","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1796","url":null,"abstract":"In many regions of the globe, pyogenic spondylitis remains a significant concern. It is a disorder that affects a very small proportion of the population, but it can be quite severe and even fatal. Frequently, it is difficult to make a diagnosis due to the absence of evident signs or symptoms. It encompasses a vast array of clinical entities, including pyogenic spondylodiscitis, discitis, vertebral osteomyelitis, and spinal osteomyelitis, among others. The success rates of conservative treatment are comparable to those of surgical treatment, but complications and mortality rates are lower. In the absence of a clear indication for surgical intervention, conservative treatment should be considered first. Patients with cervical tract or tuberculous spondylodiscitis should endure closer diagnostic and clinical monitoring due to the increased risk of developing bone collapse and neurological deficits.","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132502935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ONE- STEP COMPARED WITH TWO-STEP GESTATIONAL DIABETES SCREENING AND PREGNANCY OUTCOMES : A SYSTEMATIC REVIEW","authors":"Yunike Putri Nurfauzia","doi":"10.53555/nnmhs.v9i8.1788","DOIUrl":"https://doi.org/10.53555/nnmhs.v9i8.1788","url":null,"abstract":"Background: Carbohydrate disorders, including gestational diabetes mellitus (GDM) and pregestational diabetes, have significant impacts on maternal, fetal, and neonatal health. \u0000Aim: This study aims to conduct a systematic review and analyze pooled data to evaluate how the choice of GDM testing strategy influences pregnancy outcomes. \u0000Methods: This systematic review adhered to the PRISMA guidelines. The study question and eligibility criteria were defined using the PICOT method, focusing on pregnant patients and comparing IADPSG one-step to Carpenter-Coustan two-step testing in the late mid-trimester \u0000Results: Three randomized controlled trials (RCTs) were included, involving a total of 2,333 participants. The one-step approach demonstrated a non-significant difference in GDM incidence compared to the two-step approach. However, the one-step approach was associated with significantly improved maternal and perinatal outcomes \u0000Conclusion: This systematic review provides insights into the comparison of One Step versus Two Step approaches for gestational diabetes screening and their impact on maternal and perinatal outcomes. While the incidence of GDM did not significantly differ between the two approaches","PeriodicalId":347955,"journal":{"name":"Journal of Advance Research in Medical & Health Science (ISSN: 2208-2425)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122253377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}