SVU International Journal of Medical Sciences最新文献

{"title":"Response of axonal regeneration in chronic Bell's palsy to low intensity shockwave therapy: Randomized control trial","authors":"Abdelrazak A. Ahmed, M. Elshazly, M. Asal, E. Moubarak, Mohamed Rafat Borham Hussein, Islam El Malky","doi":"10.21608/svuijm.2022.174661.1446","DOIUrl":"https://doi.org/10.21608/svuijm.2022.174661.1446","url":null,"abstract":"Background : Bell’s paralysis is an acute paralysis onset due to idiopathic facial nerve inflammation It is the commonest cause of lower motor neuron facial paralysis with an annual rate of 15-30 per 100,000. Objectives: Our aim of the study to detect the difference of axonal regeneration response in chronic Bell’s palsy to low intensity radial shock wave therapy and kabbat exercises Patients and methods : 60 chronic bell’s palsy patients (six months post injury) with age 35-60 years old randomly allocated to one of two groups; group A [Shock Wave (SW)](n=30) treated with low intensity shock wave plus kabbat exercises and facial muscle exercise for six weeks. KE (kabbat exercise) group (n=30) treated with kabbat exercises plus sham treatment by a shock wave and facial muscle exercise for six weeks. patients were assessed by electrophysiological study (Amplitude and degeneration index of facial nerve). The assessment was done before and after treatment. Results : Degeneration index decrease significantly in the group A (p < 0.001), but not in the group B (p = 0.295). Amplitude of facial nerve was low at baseline, indicating sever axonal degeneration. After treatment, amplitude increased significantly in the two groups; however, the significance was higher in group A (SW) than group B (KE)(p < 0.001). Conclusion : low intensity shock wave therapy is safe and effective treatment of chronic bell’s palsy after 6 months from the onset.","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79644724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine Infusion for Post-Mastectomy Pain improves Patients' Quality of Life and Surgeons' Satisfaction","authors":"Mohamed A. Khashaba, Emad El-Dein M. Abdel Hafez, Shereen M. Abdul Wahab, M.H. Abdel Rahman","doi":"10.21608/svuijm.2022.175486.1448","DOIUrl":"https://doi.org/10.21608/svuijm.2022.175486.1448","url":null,"abstract":"Background: Cancer breast is the commonest cancer affecting females and mastectomy is still the standard therapy. However, uncontrolled intraoperative (IO) and postoperative (PO) pain will progress for long-term and affects patients' quality of life (QOL). Objectives: The effect of perioperative dexmedetomidine (DEX) and Ketamine/Midazolam (KET/MID) infusions on the incidence and severity of postmastectomy pain (PMP) and patients' QOL. Patients and methods: 120 women were randomly divided into Placebo, K/M and DEX groups. Bolus dose (0.5 ml/kg) was given over 10-min before induction, followed by IO and PO infusions at rate of 0.25 and 0.1 ml/ kg/h, respectively. PMP was evaluated at time of discharge and two monthly for 6-m PO for pain sensation with assessment of the neuropathic character of pain using Douleur Neuropathique-4 questionnaire. Patients' QOL at the 6 th month PO was evaluated using the Short-form questionnaire and surgeon's satisfaction was evaluated using 5-point scale. Results: incidence of PMP was 55%, 35% and 22.5% in placebo, K/M and DEX groups, respectively. Median PMP score was significantly lower with DEX than other infusions and with K/M than Placebo infusion. Neuropathic pain scoring was significantly higher with placebo than other infusion. Patients' QOL and surgeon's satisfaction scorings were significantly higher with DEX and K/M infusions than Placebo infusion and with K/M infusion than Placebo infusion. Conclusion: Perioperative DEX or KET infusion significantly reduced the incidence and severity of PMP with improvement of patients' QOL and surgeon's satisfaction. DEX perioperative infusion provided superior outcome than K/M infusion.","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77924283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the use of Resazurin for Rapid Antifungal Susceptibility Testing","authors":"Omnia Taher","doi":"10.21608/svuijm.2022.137123.1311","DOIUrl":"https://doi.org/10.21608/svuijm.2022.137123.1311","url":null,"abstract":"","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81010498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Microbiology of Surgical Site Infection Following Hysterectomy at a South African Quaternary Hospital","authors":"Karthick Naidoo, Y. Moodley","doi":"10.21608/svuijm.2022.135351.1303","DOIUrl":"https://doi.org/10.21608/svuijm.2022.135351.1303","url":null,"abstract":"","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72937447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role Of Contrast-Enhanced Magnetic Resonance Imaging and Diffusion- Weighted Magnetic Resonance Imaging In evaluation of the pancreatic Lesions","authors":"A. Okasha, G. Abd-Elrazek, M. Negm, S. Abd-Elghani","doi":"10.21608/svuijm.2022.116250.1265","DOIUrl":"https://doi.org/10.21608/svuijm.2022.116250.1265","url":null,"abstract":"As a result, one of the leading causes of poor prognosis is that many lesions go untreated until they have progressed or are no longer surgically resectable. Despite data from various trials showing that screening individuals with a family history of pancreatic cancer is associated with more curative resections (P = 0.011) and enhanced median survival (p 0.001), pancreatic cancer screening programs for the general population are not currently recommended (Zhang et al., 2017). A cystic pancreatic lesion can be detected by abdominal ultrasound (US). However, this approach lacks acceptable spatial and soft-tissue resolutions, and picture quality suffers significantly in obese individuals. When compared to abdominal ultrasound, endoscopic ultrasound (EUS) can provide better images; nonetheless, EUS is an intrusive procedure.(Kalb et al., 2009).","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80224482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study between Protective Effects of L-Carnitine and Curcumin on Nephrotoxicity Induced by Cisplatin in Adult Male Albino Rats","authors":"Noha Aboelnaga Ashour, D. Mohamed, Maha Ahmed","doi":"10.21608/svuijm.2022.115758.1264","DOIUrl":"https://doi.org/10.21608/svuijm.2022.115758.1264","url":null,"abstract":"Background: Cisplatin is regarded as a main anticancer drug. However, nephrotoxicity is its major side effect and chief dose-limiting factor. L-carnitine (LC) is a natural nutrient, while Curcumin (CMN) is derived from turmeric (Curcuma longa) plants. Both could prevent nephrotoxicity. Objectives: To evaluate nephrotoxicity induced by cisplatin ,detect protective effect of L-carnitine and curcumin in reducing cisplastin nephrotoxicity and determine which is more potent . Materials and Methods: Forty adult male albino rats were randomly divided into 4 groups ten rats each; Group1; Control group, received isotonic saline, 2. Group 2; cisplatin treated (7mg/kg body weight as a single dose), Group 3; treated with LC (500 mg/kg/day) plus cisplatin, Group 4; treated with cisplatin plus CMN (100mg/kg /day).The duration of experiment was 10 days. Specimens were prepared for light and electron microscopic examination. Morphometric and statistical studies were done to measure the diameter of proximal convoluted tubules (PCT) and Bowman's space. Results: The cisplatin-treated rats had destructive damage of the renal glomeruli including all types of pathological changes in the cortex and marked degeneration of the proximal convoluted tubules (PCTs). The treatment with LC and curcumin prevented severe damage caused by cisplatin. However LC treated rats showed more improvement than CMN treated group. Conclusions: Administration of L-carnitine with cisplatin decreases its nephrotoxicity which is the major cisplatin side effect.","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85759048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of MRI Spectroscopy in diagnosis of brain Glioma: A Cross-Sectional Study","authors":"A. Okasha, A. R. Hamdan","doi":"10.21608/svuijm.2022.114633.1262","DOIUrl":"https://doi.org/10.21608/svuijm.2022.114633.1262","url":null,"abstract":"Background: Glioma a common type of the brain tumor, which originates in the glial cells that surround and support neurons in the brain, including astrocytes, oligodendrocytes and ependymalcells. Objectives: This study is aiming to investigate the role of MRS in patients in diagnosis of brain glioma. Patients and methods: The study was designed as a cross-sectional study recruit 30 patients, who were referred to the Radio-diagnosis Department of South Valley University Hospitals for suspected glioma from neurosurgery department during the period from February 2018 to Aug 2021 the study protocol was approved by the local ethics committee of South valley University hospitals (Ref No Code Ms-4–2018, Date of approval 10–02-2018). and it was approved by the local Research Ethics Committee of our hospital. Results: The study included 30 patients with age ranged from six to 72 years old. The lesions within the repetitive tumor group had essentially higher Cho/Cr ratios than those within the radiation damage group (p < 0.0001; SE, 0.18), and these, also, had vitally higher Cho/Cr proportions than the typical white matter of 6 patients (p = 0.0003; SE, 0.09). In differentiating tumor versus non-tumor lesions, the sensitivity and specificity of Cho/NAA ratio greater than 2.0 was 96% and 70%, respectively. For ratios higher than 2.5, the sensitivity and specificity to detect tumors was 97% and 86%, respectively. Conclusion: MRS examination was greatly beneficial in differentiating neoplastic from non-neoplastic lesions and decrease for stereotactic brain biopsy. However, further studies are required to confirm the","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80548176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Hormonal Contraceptives Use Among Early Married Women in Qena City","authors":"Asmaa A. Sayed, A. Hany, M. Iwes","doi":"10.21608/svuijm.2022.114291.1261","DOIUrl":"https://doi.org/10.21608/svuijm.2022.114291.1261","url":null,"abstract":"Background: Marriage in young age is a very common problem in Egypt. According to Central agency for public mobilization and statistics in Egypt, Qena is the first government in early marriage by 12.8 per 1000 person. This indicates the great reproductive problem that faces women like unintended pregnancy and maternal mortality. Objectives: Assessment effect of marriage age on contraceptives behaviors. Also, to identify other factors that can affect using of hormonal contraception methods like education, husband opinion about family planning idea and socioeconomic level. Patients and methods: At family planning clinics of five primary health care units in Qena city this cross-sectional study was conducted on 400 married females in reproductive aged 15:49 years to detect relation between marriage before legal age (18 years) and practicing family planning. There are two groups, female married before 18 years and that married at or after 18 years. A structured questionnaire was used. Results: There is a significant relation between marriage age and hormonal contraceptives use, about 73.2% of female included in our study use contraception methods and married after age of eighteen (pvalue = 0.001). According to logistic regression analysis husband opinion is the most contributing factor associated with use of Contraception (pvalue <0.0001) while the least contributing factor is husband education (P-value=0.064). Conclusion: Using of hormonal contraception was low among females married before age of eighteen so their family size is higher. Education plays a vital role in practicing family planning.","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86193565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of different types of laparoscopic bariatric procedures on type 2 diabetic obese patients","authors":"M. Ahmed, Ahmed Mohamed Safy, Wael Nabil Abdel-slam, H. Hussein","doi":"10.21608/svuijm.2022.114993.1263","DOIUrl":"https://doi.org/10.21608/svuijm.2022.114993.1263","url":null,"abstract":"Background: The rising global incidence and prevalence of type II diabetes (T2DM) has paralleled the rise in obesity. Bariatric surgery is currently the most effective treatment for obesity compared to maximal medical and lifestyle management. Objectives: This work aimed to compare the efficacy and safety of LSG (group 1), (LRYGB) (group 2) and (MGB) (group 3) for T2DM obese patients. Patients and Methods: A randomized prospective clinical study for 225 patients with morbid obesity (BMI 35 kg/m 2 or more with T2DM) treated by laparoscopic sleeve gastrectomy (LSG),laparoscopic Roux-en-Y gastric bypass(LRYGB) and mini gastric bypass (MGB),(75 patients in each group) conducted in Qena and Alexandria university hospitals from March 2019 to September 2020.The primary outcome was complete remission of type 2 diabetes with hyperglycemia control, (HbA1c <6 %). The secondary outcome was weight loss is by calculating the percentage of excess weight loss (% EWL) Results: There was statistically significant difference between the three studied groups regarding time of surgery (96.5 ± 17.6, 107.3 ± 19.4, and 106.6 ± 15.8 among group 1, 2, and 3respectively; P-value < 0.05). There was no statistically significant difference between the three studied groups regarding hospital staying duration and postoperative complication. There was no statistically significant difference between the three studied groups regarding HbA1C postoperative. Conclusion: Metabolic surgery has emerged as the single most effective treatment option for T2DM and obesity. There is a potential superiority of the LRYGB and MGB over the LSG in obtaining diabetes remission.","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86122388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agonist hold Antagonist Protocol versus Antagonist Protocol in Intracytoplasmic Sperm Injection for Infertile Patients with Polycystic Ovary Syndrome","authors":"H. Ahmed, Mahmoud I Alrashidy, O. A. M. Ali, A. Abdellah","doi":"10.21608/svuijm.2022.113449.1259","DOIUrl":"https://doi.org/10.21608/svuijm.2022.113449.1259","url":null,"abstract":"Introduction Polycystic Ovary Syndrome (PCOS) is the most common endocrinopathy in reproductive-aged women in the United States, affecting around 7% of women. Although the specific cause of PCOS is unknown, it is assumed to be caused by a complex interplay of hereditary and environmental factors. Changes in luteinizing hormone (LH) action, insulin resistance, and a probable propensity to hyperandrogenism have all been related to the pathophysiology of PCOS (Dafopoulos et al., 2009). The importance of ovarian stimulation in the success of in vitro fertilization and embryo transfer (IVF-ET) treatment has long been recognised. As a result, since the 1980s, a gonadotropin releasing hormone (GnRH) agonist protocol has been created and used in the context of IVF-ET treatment. By desensitising pituitary receptors, the GnRH agonist regimen is aimed to restrict the release of pituitary follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (Huirne et al., 2007). The introduction of a GnRH antagonist regimen, which blocks pituitary receptors, has recently provided another option for ovarian stimulation. The use of a GnRH antagonist strategy has been shown to minimize the length of the ovulatory stimulu sand the occurrence of ovarian hyperstimulation syndrome. The shorter time of analogue medication, the shorter duration of FSH stimulation, and the lesser chance of developing ovarian hyperstimulation syndrome (OHSS) are all advantages of antagonists (Al-Inany et al. ,2016). Because the GnRH antagonist protocol is straightforward, convenient, and flexible, and because it does not cause functional ovarian cysts or \"menopausal\" symptoms like the agonist protocol, many doctors and patients like it. However, results from randomised clinical trials show that the antagonist protocol retrieves fewer oocytes and has lower pregnancy rates than the agonist long treatment (Kim CH et al., 2011). Abstract Background: Polycystic Ovary Syndrome (PCOS) is currently thought to emerge from a complex interaction of genetic and environmental traits.Polycystic Ovary Syndrome is the most common endocrinopathy among reproductive-aged women Objectives: The aim of this study was to compare between agonist hold antagonist protocol and antagonist protocol in ICSI for Infertile patients with PCOs as regard the number of oocytes retrieved, fertilization rate, implantation rate and clinical pregnancy rate. Patients and methods: This was a prospective comparative study, which was conducted at Assisted Reproduction Unit at Qena University Hospital.This work had been conducted on infertile women with PCOS undergoing ICSI in ART unit in obstetrics and gynecology department, Qena University hospital from January 2019 to June 2020. Results: The number of implanted embryos was significantly higher in agonist hold antagonist protocol group compared to antagonist protocol group (p<0.001).Also, clinical pregnancy was found to be significantly higher in agonist hold antagonist protocol gro","PeriodicalId":34789,"journal":{"name":"SVU International Journal of Medical Sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74736621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}