Apollo Medicine最新文献

{"title":"Primary Central Nervous System Lymphoma Masquerading as Brain Metastasis","authors":"Chee Yik Chang","doi":"10.4103/am.am_157_23","DOIUrl":"https://doi.org/10.4103/am.am_157_23","url":null,"abstract":"IN A 41-year-old woman with no prior medical illness presented with a 1-month history of slurred speech and left hemiparesis. In addition, she had been experiencing progressive dysphagia for the past 2 weeks. Upon arrival at the hospital, her Glasgow Coma Scale score was E4 (blank stare), V1, and M5. Blood investigations were within normal limits, and HIV test was nonreactive. A contrast-enhanced computed tomography (CT) brain scan showed multiple enhanced lesions in the right frontal lobe and basal ganglia, suggesting metastasis [Figure 1]. A CT scan of the thorax, abdomen, and pelvis was performed, but no primary lesion was identified. A positron emission tomography scan was not performed because it was not available at our facility. To establish a definitive diagnosis, a burr hole and biopsy were performed. The histopathological examination of the biopsy sample indicated non-Hodgkin lymphoma with a B-cell phenotype (positive for CD10, CD20, and BCL-6 on immunohistochemical staining). Based on these findings, the patient was diagnosed with primary central nervous system lymphoma (PCNSL). Following the diagnosis, the patient’s condition further deteriorated while in the ward despite being on steroids. The health-care team offered the patient chemotherapy and radiotherapy as treatment options. Unfortunately, the family expressed reluctance to pursue aggressive treatment, and as a result, the patient was offered palliative care focusing on symptom relief.Figure 1: A contrast-enhanced computed tomography brain scan showing multiple enhanced lesions in the right frontal lobe and basal gangliaPCNSL is a rare type of extra-nodal B-cell non-Hodgkin lymphoma with a focus located in the brain, leptomeninges, spinal cord, or eyes. It is an extremely aggressive disease that carries a poor prognosis, with a 5-year survival rate of 30.1%.[1] HIV infection is associated with an increased risk of B-cell lymphoma, and life-threatening complications have previously been reported.[2-4] A large proportion, up to 80%, of patients with PCNSL experience focal neurological deficits, with the symptoms often corresponding to the location of the lesion within the central nervous system. The most common clinical manifestation is cognitive impairment, which is frequently accompanied by difficulties in thinking, memory loss, confusion, and changes in behavior. Gait disturbances, such as problems with balance and coordination, are also commonly observed.[5] On brain imaging, the most common locations of PCNSL are periventricular white matter, basal ganglia, and corpus callosum; single lesions account for 70% of cases and multiple lesions account for 30% of cases.[6] Treatment options for PCNSL typically involve chemotherapy, radiation therapy, or a combination of both.[7] However, in this particular case, the patient’s family opted for palliative care, focusing on managing symptoms, and providing comfort during the end-of-life phase. Conflicts of interest There are no confli","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Angiomyomatous Nasal Polyp of Angiomyomatous Nasal Polyp - A Case Report","authors":"Vinod Kumar Gonuru, Sridhar Reddy Dandala, Siri Nadella","doi":"10.4103/am.am_206_22","DOIUrl":"https://doi.org/10.4103/am.am_206_22","url":null,"abstract":"Abstract Introduction and Objective: Angiomatous nasal polyps are distinct variants, constituting only 2%–5% of all sinonasal polyps. The heretofore-reported case of angiomyomatous nasal polyp is a unique entity and is infrequently reported in the literature. Case Report: A 56-year-old male presented with chief complaints of intermittent epistaxis, progressive obstruction of the left nasal cavity, and discharge for 8 months. An endoscopic examination of the nasal cavity was performed, which showed a soft, fleshy polypoid mass in the left lateral wall posterior to the posterior end of the middle meatus with no active bleeding. The clinical findings led to a provisional diagnosis of an antrochoanal polyp, whereas computed tomography gave an impression of an angiomatous polyp, and then the patient was taken up for endoscopically-assisted excision of the nasal mass. The surgery was performed under general anesthesia. Histopathological examination reported it to be an angiomyomatous nasal polyp. The patient’s recovery was uneventful, and follow-up revealed no remission. Conclusion: Angiomyomatous nasal polyps are a unique entity that can be difficult to diagnose with differentials. Endoscopic resection is the treatment of choice, and local recurrence is unlikely.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of WHO Pain Ladder Management versus Severity-based Pain Management in Patients Presented with Acute Abdominal Pain Visiting Emergency Department","authors":"Mahasweta Choudhury, Nithyanand Mathiazhagan, J. Shiva Ranjan Reddy","doi":"10.4103/am.am_116_23","DOIUrl":"https://doi.org/10.4103/am.am_116_23","url":null,"abstract":"Abstract Aimand Objectives: The present study was undertaken to evaluate whether patients that are administered analgesics depending on their initial pain severity are more satisfied with their treatment than those who are given analgesics in accordance with the WHO pain ladder management protocol. Materials and Methods: First consecutive 100 patients (Group I) with abdominal pain were treated with WHO pain ladder management and for the next 100 patients (Group II), the pain management was done based on their intensity of pain. All patients were assessed for relief of pain every 15 min based on visual analog scale (VAS). Results: The visual analog pain score started decreasing after the administration of analgesics in both groups. The VAS was monitored once every 15 min for 60 min and in each measurement, the score was slightly lower in Group II in comparison to Group I ( P > 0.05). At the end of 60 min, the mean score was <4 in both groups. Eighty-six percentage of the patients in Group II and 79% of the patients in Group I were satisfied with their pain relief. Although the satisfaction level of patients was higher in Group II, it was not found to be statistically significant ( P = 0.282). Conclusion: The usage of analgesics for pain management can be decided based on the severity of the pain instead of following the pain ladder management proposed by WHO. This can prevent the unnecessary usage of analgesics such as paracetamol and certain side effects due to that.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-care-seeking Behavior of Postmenopausal Women in an Urban Slum of Srikakulam Town","authors":"Paromita Roy, Saptarishi Bose, Tarun Kumar Suvvari, Nagarjuna Sivaraj","doi":"10.4103/am.am_165_23","DOIUrl":"https://doi.org/10.4103/am.am_165_23","url":null,"abstract":"Abstract Introduction: The majority of Indian women tend to ignore and neglect their menopausal symptoms, which can diminish in intensity over time, leading to a reduced health-related quality of life. We aimed to assess the health-care-seeking behavior of postmenopausal women in light of the increasing burden of menopausal symptoms. Methodology: A cross-sectional study was carried out within urban neighborhoods, involving 384 postmenopausal women aged 45–60, to investigate the health-related issues they faced. The Menopause Rating Scale (MRS) was used to assess the symptoms experienced during the postmenopausal stage. In addition, a predesigned and pretested questionnaire was used to gather information on their health-care-seeking behavior. The participants underwent a comprehensive physical examination, including anthropometric measurements. To analyze the data, descriptive statistics were used. Results: The results showed that 34% of the 384 women were between the ages of 45 and 49 years. Based on the MRS assessment, it was found that around 70% of women experienced mild symptoms, whereas 24% had moderate symptoms, and a mere 2% reported severe symptoms. Regarding treatment, approximately 85% of women had sought medical intervention. However, satisfaction with the treatment was reported by only 71% of the participants. Among the women with modest symptoms, 70% received medical care, compared to 28% of the women with moderate symptoms. Women who were employed, widowed, three-generation family women, and Class IISES women made the most use of health-care facilities, with 90%, 89%, 88%, and 97%, respectively. Conclusion: The prevalence of faint symptoms was significantly higher than that of moderate and severe symptoms. Although most women sought treatment, many were unsatisfied with it. Therefore, behavior modification communication is necessary among postmenopausal women who seek medical care. In addition, the National Health Mission should incorporate components addressing the specific health requirements of postmenopausal women.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Hepatitis B Virus DNA Forecast Chronic Hepatitis in Hepatitis B Surface Antigen-positive Patients?","authors":"Kaviya Chella Pandi, Poongodi Santhana Kumarasamy","doi":"10.4103/am.am_182_23","DOIUrl":"https://doi.org/10.4103/am.am_182_23","url":null,"abstract":"Abstract Introduction: Chronic hepatitis B (CHB) infection is accountable for nearly 240 million cases worldwide. Hepatitis B virus (HBV) has a propensity to show a divergent phase, and isolated measure of high HBV DNA level may not reflect the stage of the disease. In this background, this study was done to detect hepatitis B e antigen (HBeAg) and HBV DNA levels among hepatitis B surface antigen (HBsAg)-positive CHB cases and to determine the stage of disease with viral markers and biochemical parameters such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Materials and Methods: Blood samples were collected from 50 participants with CHB (HBsAg positive for more than 6 months) tested for HBe Ag by enzyme-linked immunosorbent assay, HBV DNA, ALT, and AST levels. Results: Among the 50 cases, 31 (62%) were HBeAg negative. Among these 31 HBeAg-negative groups, 16 (52%) had HBV DNA levels &gt;2000 IU/mL. In these 16 patients, six had ALT &gt;40IU/mL. Conclusion: HBsAg, HBeAg, ALT levels, and HBV DNA are important markers to determine the clinical stage of the disease. Since it is a chronic disease, patients need long-term follow-up. Further, emergence of viral mutants among vaccinated and those on lamivudine aggravates the existing problem.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135148404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Magnetic Resonance Imaging in Dementia","authors":"Divyashree Koppal, Shagufta Wahab, Deoshree Akhouri, Ibne Ahmad","doi":"10.4103/am.am_147_23","DOIUrl":"https://doi.org/10.4103/am.am_147_23","url":null,"abstract":"Abstract Background: Dementia is a condition of elderly individuals, marked with emotional and cognitive disabilities which are severe enough to impair their routine daily life and its quality. It is mainly a disease affecting elderly population with an approximate prevalence rate of 1% at the age of 60 years and quadruples every 10 years, up to 30%–50% by the age of 85 years. There are about 5.5 crore people suffering with dementia with more than 60% in developing countries.To overcome this, a multipronged strategy with timely diagnosis is the need of the hour. Materials and Methods: The present study was conducted at the Department of Radiodiagnosis and Department of Psychiatry of J. N. Medical College and Hospital, Aligarh, over a period of 2 years. Forty-five patients in the age group of more than 55 years who presented with the complaints of cognitive impairment and were referred for magnetic resonance imaging (MRI) head after clinical examination and Mini–Mental State Examination (MMSE) score assessment were included in the study. On MRI images are assessed using the Global Cortical Atrophy (GCA) scale, medial temporal lobe (MTL) atrophy scale, and Fazekas Scale, then findings are correlated with clinical MMSE scores. Results: There were 45 patients with the age group of more than 50 years, among 66.67% of patients were males and 33.33% of patients were females. In 60.00% of patients, socioeconomic status was lower middle class, 46.67% of patients were illiterate followed by studied till primary school (22.22%). In 66.67% of patients, mini–mental score examination score was mild. Among the imaging scales, 82.22% of patients showed moderate GCA scale; in 55.56% of patients, interpretation of MTL atrophy scale was widening of choroid fissure and temporal horn of lateral ventricle. 33.33% of patients showed Fazekas 3 Scale with large confluent lesions. All these imaging scales showed a significant negative correlation with MMSE scores. Conclusion: MRI plays an important role in the assessment of structural changes in patients presenting with cognitive impairment as well as it points toward the diagnosis of certain type of dementia depending on the involvement of specific areas or lesions and their distribution in the cerebral hemispheres. Visual assessment using various scales has helped in assessing the severity as well as possible type. There has been establishment of significant correlation between the MRI scales of atrophy and clinical MMSE scoring system.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstacles in Dengue Diagnosis and Severity Prediction","authors":"Latha Bharathi Chidambaram, Poongodi Santhana Kumarasamy","doi":"10.4103/am.am_183_23","DOIUrl":"https://doi.org/10.4103/am.am_183_23","url":null,"abstract":"Abstract Background: Dengue emerges as a perennial public health menace. Identification of patients at risk of developing dengue hemorrhagic fever (DHF)/dengue shock syndrome is still a huge challenge. Objective: In this background, this study was done to predict the severity of dengue by measuring the interleukin (IL) 6 and IL8 by enzyme-linked immunosorbent assay (ELISA). Materials and Methods: A total of 88 samples were collected from patients with clinical signs suggestive of dengue were tested for NS1 and immunoglobulin (Ig) M (NIV Pune), and proinflammatory markers IL-6 and IL-8 (Diaclone SAS Pvt Ltd., France) by ELISA. Results: All the 88 patients were positive for dengue IgM. Dengue NS1 was positive in 36 patients. IL-6 and IL-8 were raised in 56 cases and 46 cases, respectively. Out of 32 severe dengue cases, 24 had raised IL-6 and IL-8. Conclusion: The dynamic nature of dengue requires close monitoring and frequent clinical and laboratory evaluations. Early prediction requires prompt testing of all the markers (IgM, IgG, and NS1) irrespective of the day of illness. Although cytokine estimation aids in assessing the severity, other cost-effective alternatives (hematocrit and platelet count) are copacetic.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile of Patients with Hypertensive Crisis Presenting to an Emergency Department of a Tertiary Care Hospital in Western India","authors":"Brijesh Goswami, Vivek Nanda","doi":"10.4103/am.am_121_23","DOIUrl":"https://doi.org/10.4103/am.am_121_23","url":null,"abstract":"A hospital-based retrospective study was undertaken among the adult patients presenting to document the incidence of hypertensive urgency (HTN-U) and emergency while the secondary objectives included clinical presentations, disposition from emergency room, and inhospital mortality.\u0000 \u0000 \u0000 \u0000 All patients were evaluated by vital signs, clinical examination as well as relevant laboratory tests and radiological tests. Patients with target organ damage were grouped under the hypertensive emergency (HTN-E) group (n = 104) and patients without target organ damage were included under the HTN-U group (n = 52). The data were analyzed using GraphPad Prism (vs. 9.4.1) and MedCalc (vs. 20.118).\u0000 \u0000 \u0000 \u0000 The incidence of HTN-E and HTN-U was 68.4% and 31.6%, respectively. The most common symptom observed in patients with HTN-E was breathlessness (53.8%), followed by chest pain (34.6%) and headache (27.9%). While, in HTN-U patients, most patients reported chest pain (43.8%), headache (39.6%), and epistaxis (22.9%). Majority of the patients in both the groups presented with signs of tachycardia, tachypnea, and hypoxia. The mortality in HTN-E and HTN-U patients was 15.4% and 2.1%, respectively. Among 104 patients with HTN-E, 53.8% each of the patients had acute heart failure and acute pulmonary edema. While, in HTN-U patients, acute pulmonary edema and acute coronary syndrome were observed in 2.1% each of the study subjects.\u0000 \u0000 \u0000 \u0000 Patients at high risk or end-organ damage should be immediately referred to the emergency department from the outpatient settings, as a rapid reduction in blood pressure is essential over minutes to hours, to prevent further organ damage.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Cases of Giant Congenital Melanocytic Nevus – A Rare Case Report with Review of Literature","authors":"Padmapriya Balakrishnan, Thirunavukkarasu Arun Babu","doi":"10.4103/am.am_151_23","DOIUrl":"https://doi.org/10.4103/am.am_151_23","url":null,"abstract":"Abstract Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condition is rare, affecting approximately 1 in every 200,000 to 500,000 births. There is a lifetime risk of 5%–40% for the development of malignant melanoma from the nevus. Early detection of the lesion and regular monitoring are crucial in order to identify any malignant changes. In this report, we present two cases of giant congenital melanocytic nevus, highlighting its rarity, and provide a literature review on the subject.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Carotid Intima-Media Thickness with One-hour Postload Plasma Glucose (1h-PPG) in Overweight and Obese North Indian Adults","authors":"Gautam Jesrani, Monica Gupta, Narinder Kaur, Samiksha Gupta","doi":"10.4103/am.am_178_23","DOIUrl":"https://doi.org/10.4103/am.am_178_23","url":null,"abstract":"Abstract Background: Cardiovascular morbidities like arterial stiffness and atherosclerosis have a negative association with insulin resistance, which can be identified by carotid intima media thickness (CIMT) measurement. One-hour postload plasma glucose (1 h-PPG) is a novel marker for early identification of insulin resistance, but very few studies are available on its relationship with CIMT. Objective: To identify the correlation of CIMT with 1 h-PPG in overweight and obese adults without diabetes. Methods: Individuals not having known diabetes or other chronic illnesses were identified and subjected to the initial anthropometric analysis for body mass index (BMI) calculation. A standard oral glucose tolerance test was performed on individuals with a BMI of ≥25 kg/m 2 for 1 h-PPG values, and a B-mode ultrasound scan of the neck was used for CIMT measurement. A Pearson’s correlation statistical test was applied for correlation identification. Results: A total of 94 nondiabetic individuals participated, of whom 55 (58.5%) were women. Mean age, BMI, and CIMT values of the study population were 38.8 (±8.09) years, 29.6 (±3.22) kg/m 2 , and 0.72 (±0.10) mm, respectively. Average 1 h-PPG levels were 150.7 (±21.11) mg/dl, and the Pearson’s coefficient ( r ) value with CIMT was 0.5792 ( P < 0.05). Further, correlation analysis demonstrated an r -value of −0.0029 for BMI, −0.1293 for waist-hip ratio, −0.0047 for waist-height ratio, 0.3862 for glycated hemoglobin (HbA1c), and −0.2930 for 2 h-PPG. Conclusion: In euglycemic adults, the early insulin resistance defining parameter, i.e., 1 h-PPG levels had a consistent positive correlation with CIMT, which is a marker of the initial stages of atherosclerosis.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135147699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}