巨大先天性黑素细胞痣2例并文献复习

Padmapriya Balakrishnan, Thirunavukkarasu Arun Babu
{"title":"巨大先天性黑素细胞痣2例并文献复习","authors":"Padmapriya Balakrishnan, Thirunavukkarasu Arun Babu","doi":"10.4103/am.am_151_23","DOIUrl":null,"url":null,"abstract":"Abstract Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condition is rare, affecting approximately 1 in every 200,000 to 500,000 births. There is a lifetime risk of 5%–40% for the development of malignant melanoma from the nevus. Early detection of the lesion and regular monitoring are crucial in order to identify any malignant changes. In this report, we present two cases of giant congenital melanocytic nevus, highlighting its rarity, and provide a literature review on the subject.","PeriodicalId":34670,"journal":{"name":"Apollo Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Two Cases of Giant Congenital Melanocytic Nevus – A Rare Case Report with Review of Literature\",\"authors\":\"Padmapriya Balakrishnan, Thirunavukkarasu Arun Babu\",\"doi\":\"10.4103/am.am_151_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condition is rare, affecting approximately 1 in every 200,000 to 500,000 births. There is a lifetime risk of 5%–40% for the development of malignant melanoma from the nevus. Early detection of the lesion and regular monitoring are crucial in order to identify any malignant changes. In this report, we present two cases of giant congenital melanocytic nevus, highlighting its rarity, and provide a literature review on the subject.\",\"PeriodicalId\":34670,\"journal\":{\"name\":\"Apollo Medicine\",\"volume\":\"42 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Apollo Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/am.am_151_23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Apollo Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/am.am_151_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

摘要先天性黑素细胞痣是指出生时出现的一种色素沉着的皮肤病变。它的特点是黑色素细胞在表皮、真皮和皮下组织中良性生长。当病变覆盖身体的面积较大,超过20cm时,称为巨大先天性黑色素细胞痣(GCMN)。这种情况的发生是罕见的,大约每20万至50万新生儿中就有1例。从痣发展为恶性黑色素瘤的终生风险为5%-40%。早期发现病变和定期监测是至关重要的,以确定任何恶性变化。在此报告中,我们提出两例巨大的先天性黑素细胞痣,强调其罕见性,并提供有关该主题的文献综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Two Cases of Giant Congenital Melanocytic Nevus – A Rare Case Report with Review of Literature
Abstract Congenital melanocytic nevus refers to a pigmented skin lesion present at birth. It is characterized by the benign growth of melanocytes in the epidermis, dermis, and subcutaneous tissue. When the lesion covers a larger area of the body, exceeding 20 cm, it is referred to as a giant congenital melanocytic nevus (GCMN). The occurrence of this condition is rare, affecting approximately 1 in every 200,000 to 500,000 births. There is a lifetime risk of 5%–40% for the development of malignant melanoma from the nevus. Early detection of the lesion and regular monitoring are crucial in order to identify any malignant changes. In this report, we present two cases of giant congenital melanocytic nevus, highlighting its rarity, and provide a literature review on the subject.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
34
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信