Progress in Transplantation (Aliso Viejo, Calif.)最新文献

{"title":"A Cross-Sectional Study of the Association Between Chronic Oral Disease Burden and Serum Biomarkers in Kidney Transplant Recipients.","authors":"Layna Cristine Brito Rocha,&nbsp;Danila Lorena Nunes-Dos-Santos,&nbsp;Elisa Miranda Costa,&nbsp;Samira Vasconcelos Gomes,&nbsp;Vandilson Pinheiro Rodrigues,&nbsp;Antonio Luiz Amaral Pereira","doi":"10.1177/15269248211064889","DOIUrl":"https://doi.org/10.1177/15269248211064889","url":null,"abstract":"<p><strong>Introduction: </strong>Poor oral health can negatively affect general health and quality of life of kidney transplant recipients. The study aimed to investigate the association between chronic oral disease burden, serum biomarkers, and comorbidities in kidney transplant recipients.</p><p><strong>Design: </strong>A cross-sectional comparative study was conducted with 44 patients after kidney transplant. The burden of chronic oral disease was composed of the following observable variables: moderate periodontitis and presence of dental caries. Serum biomarkers and comorbidities data were collected. The chi-square or Fisher's exact tests for categorical variables and Student's <i>t</i>-test or Mann-Whitney test for continuous variables were used. Robust Poisson regression was used to model the association.</p><p><strong>Results: </strong>Higher levels of mean uric acid (<i>P</i> = .01) and creatinine (<i>P</i> = .03) were observed in the group of patients with oral disease burden, while the highest level of high-density lipoprotein was observed in the group without oral disease. Higher values of uric acid were associated with the occurrence of chronic oral disease burden (Adjusted PR = 1.24, 95% CI: 1.03-1.48, <i>P</i> = .019). There was no statistical difference between the groups with and without oral disease burden in comorbidities present.</p><p><strong>Conclusion: </strong>The findings suggest that chronic oral diseases burden can be associated with uric acid and creatinine levels in kidney transplant recipients.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"49-54"},"PeriodicalIF":0.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39682278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Dialysis Center Educational Video Intervention Increases Patient Self-Efficacy and Kidney Transplant Evaluations.","authors":"Thomas A Morinelli,&nbsp;David J Taber,&nbsp;Zemin Su,&nbsp;James R Rodrigue,&nbsp;Zachary Sutton,&nbsp;Misty Chastain,&nbsp;Tiffany Thompkins Tindal,&nbsp;Erin Weeda,&nbsp;Patrick D Mauldin,&nbsp;Michael Casey,&nbsp;John Bian,&nbsp;Prabhakar Baliga,&nbsp;Derek A DuBay","doi":"10.1177/15269248211064882","DOIUrl":"https://doi.org/10.1177/15269248211064882","url":null,"abstract":"<p><p><b>Introduction:</b> The optimal treatment for end-stage kidney disease is renal transplant. However, only 1 in 5 (21.5%) patients nationwide receiving dialysis are on a transplant waitlist. Factors associated with patients not initiating a transplant evaluation are complex and include patient specific factors such as transplant knowledge and self-efficacy. <b>Research Question:</b> Can a dialysis center-based educational video intervention increase dialysis patients' transplant knowledge, self-efficacy, and transplant evaluations initiated? <b>Design:</b> Dialysis patients who had not yet completed a transplant evaluation were provided a transplant educational video while receiving hemodialysis. Patients' transplant knowledge, self-efficacy to initiate an evaluation, and dialysis center rates of transplant referral and evaluation were assessed before and after this intervention. <b>Results:</b> Of 340 patients approached at 14 centers, 252 (74%) completed the intervention. The intervention increased transplant knowledge (Likert scale 1 to 5: 2.53 [0.10] vs 4.62 [0.05], <i>P</i> < .001) and transplant self-efficacy (2.55 [0.10] to 4.33 [0.07], <i>P</i> < .001. The incidence rate per 100 patient years of transplant evaluations increased 85% (IRR 1.85 [95% CI: 1.02, 3.35], <i>P</i> = .0422) following the intervention. The incidence rates of referrals also increased 56% (IRR 1.56 [95% CI: 1.03, 2.37], <i>P</i> = .0352), while there was a nonsignificant 47% increase in incidence rates of waitlist entries (IRR 1.47 [95% CI: 0.45, 4.74], <i>P</i> = .5210). <b>Conclusion:</b> This dialysis center-based video intervention provides promising preliminary evidence to conduct a large-scale randomized controlled trial to test its effectiveness in increasing self-efficacy of dialysis patients to initiate a transplant evaluation.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"27-34"},"PeriodicalIF":0.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39700101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prerenal Transplant Education and Evaluation Positively Impacts Outcomes.","authors":"Michelle T Jesse,&nbsp;Erin Clifton,&nbsp;Dean Y Kim,&nbsp;Dayna Nicholson,&nbsp;Rujuta Patil,&nbsp;Shweta Bhavsar,&nbsp;Soham Desai,&nbsp;Kendyll Gartrelle,&nbsp;Anne Eshelman,&nbsp;Elizabeth Fleagle,&nbsp;Brian Ahmedani,&nbsp;Noelle E Carlozzi,&nbsp;Amy Tang,&nbsp;Anita Patel","doi":"10.1177/15269248211064888","DOIUrl":"https://doi.org/10.1177/15269248211064888","url":null,"abstract":"<p><p><b>Introduction:</b> An outstanding question in kidney transplantation is how to prepare candidates and their social supports for optimal posttransplant outcomes. <b>Project Aims:</b> This program evaluation assessed whether a pretransplant quality improvement clinic improved clinical outcomes in the year posttransplant compared to recipients receiving standard of care. <b>Design:</b> The Countdown to Transplant Clinic was implemented with kidney transplant candidates expected to receive a transplant within the next few months. The clinic included an enhanced education session on posttransplant lifestyle management, confirmation of support (≥2 adults), and evaluations by transplant social work, psychology, and nephrology. <b>Results:</b> Seventy-five patients participated in the clinic and underwent a transplant. A retrospective chart review of posttransplant laboratory values, rehospitalizations (within 3-months posttransplant), biopsy-confirmed graft failure, and mortality (within 1-year posttransplant) were collected from both groups. Univariate and multivariate propensity score-weighted linear or logistic regression models were used to evaluate the association between clinic participation and outcomes. In models adjusting for relevant covariates, participation in The Countdown to Transplant Clinic (vs standard care) was associated with a lower coefficient of variation of serum tacrolimus (all values collected 3-12 months posttransplant), 30-day posttransplant white blood cell counts (but not 90-day), 90-day posttransplant potassium, and 30 and 31 to 90 days rehospitalizations. Clinic participation did not predict serum glucose levels at 30- or 90-days posttransplant. Due to low rates of rejection and mortality, meaningful comparisons were not possible. <b>Conclusion:</b> Participation in a pretransplant, multicomponent clinic may improve certain outcomes of interest posttransplantation. Pilot testing for feasibility for randomized controlled trials is a necessary next step.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"4-10"},"PeriodicalIF":0.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39801695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Hepatitis C Viremia on Posttransplant Diabetes Mellitus in Liver Transplant Recipients.","authors":"Kelsey Klein,&nbsp;Joelle Nelson,&nbsp;Christina Long,&nbsp;Kermit Speeg,&nbsp;Naim Alkhouri,&nbsp;Reed Hall","doi":"10.1177/15269248211064879","DOIUrl":"https://doi.org/10.1177/15269248211064879","url":null,"abstract":"<p><strong>Introduction: </strong>Posttransplant diabetes mellitus (PTDM) can increase morbidity and mortality in liver transplant recipients. Although hepatitis C seropositivity is a known risk factor for PTDM, the impact of viremia versus no viremia at time of transplant is unknown.</p><p><strong>Project aims: </strong>This program evaluation sought to compare PTDM in hepatitis C seropositive patients with and without viremia at the time of liver transplant.</p><p><strong>Design: </strong>This single-center retrospective review included adult hepatitis C seropositive liver transplant recipients transplanted between January 1, 2010 to September 5, 2017 without pretransplant diabetes. Primary outcome was PTDM within 1 year. Secondary outcomes included evaluating 1-year posttransplant death-censored graft loss, mortality, and metabolic outcomes.</p><p><strong>Results: </strong>Fifty-seven liver transplant recipients with hepatitis C were included, of which 53% (n = 30) were viremic at transplant. Baseline characteristics were similar between groups. Significantly more patients with pretransplant viremia developed PTDM by 1-year posttransplant compared to the patients without viremia (43% vs 11%, <i>P</i> = 0.01). There were no differences between groups outside of more patients with viremia requiring antihypertensives by 1-year posttransplant compared to patients without viremia (57% vs 22%, <i>P</i> = 0.01).</p><p><strong>Conclusion: </strong>Liver transplant patients with hepatitis C viremia at transplant were more likely to develop PTDM at 1 year compared to those without pretransplant viremia. This is an added consideration when deciding the timing of direct-acting antiviral (DAA) utilization in the context of liver transplant for hepatitis C seropositive patients.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"73-77"},"PeriodicalIF":0.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39700099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Patients' and Living Donors' Kidney Paired Donation Educational Experiences and Recommendations for Improvement.","authors":"Rachyl Pines,&nbsp;Yaquelin Arevalo Iraheta,&nbsp;Katia A Dahmani,&nbsp;Matthew Cooper,&nbsp;Amy D Waterman","doi":"10.1177/15269248211064878","DOIUrl":"https://doi.org/10.1177/15269248211064878","url":null,"abstract":"<p><strong>Introduction: </strong>Educating potential kidney patients and living donors about the risks and benefits of kidney paired donation to ensure they make informed decisions is complex. This study aimed to increase understanding of patients' and donors' decision-making about donation, the educational content they received, and their recommendations for educational improvements.</p><p><strong>Method: </strong>We conducted a mixed methods study, including semistructured interviews and quantitative surveys, with 43 participants (25 living donors; 18 kidney recipients).</p><p><strong>Findings: </strong>Participants reported that the benefits of paired donation motivated them to participate (ie, helping multiple people, receiving a transplant sooner, flexible timing of donation). Although deciding to participate in paired donation was a systematic, logical, and carefully considered process for some. For most, it was a quickly made, often emotion-based decision. Paired donation educational content on different topics varied, with recipients reporting receiving less information than donors about donor protections and processes to ameliorate the challenges faced, such as broken swaps and chains, and delays in matching. Those who faced challenges requested more information about donor protections and support during and after paired donation. Although many acknowledged their transplant coordinators' helpfulness, participants also recommended being more proactive in learning about kidney paired donation and speaking to former donors and recipients beforehand.</p><p><strong>Discussion: </strong>Standardized, health literate educational content addressing the gaps and variability in education received may help increase paired donation informed decision-making.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"19-26"},"PeriodicalIF":0.8,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39715566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pilot Randomized Controlled Trial Comparing Levothyroxine to Placebo in Neurologically Deceased Donors.","authors":"Anne Julie Frenette,&nbsp;David Williamson,&nbsp;Virginie Williams,&nbsp;Anne-Marie Lagacé,&nbsp;Emmanuel Charbonney,&nbsp;Karim Serri","doi":"10.1177/1526924819855083","DOIUrl":"https://doi.org/10.1177/1526924819855083","url":null,"abstract":"<p><strong>Background: </strong>Although commonly prescribed, the efficacy of levothyroxine to improve heart function in neurologically deceased donors is unclear. We evaluated the feasibility of a randomized controlled trial to compare levothyroxine to placebo on the variation of left ventricular ejection fraction, in hemodynamically unstable donors.</p><p><strong>Methods: </strong>We conducted a pilot, double-blinded, randomized controlled trial. Deceased donors with reduced left ventricular ejection fraction or needing vasopressors were included. We randomized participants to a 20 μg bolus followed by a 20 μg/h infusion of levothyroxine or an identically appearing placebo. We report the proportion of recruited participants, the time to the administration of the study drug, and protocol violations.</p><p><strong>Results: </strong>Twenty-four participants (N = 24/104; 23.1%) were eligible. Five of them (N = 5/24; 20.8%) were excluded by the attending physician. Four others were not included, due to family refusal for research (n = 2/24;8.3%) and unavailability of research staff (n = 2/24; 8.3%). Fifteen participants were randomized (N = 15/104; 14.4%). Mean time between the echocardiography and the initiation of the drug was 1.73 hours, and14 (93.3%) of 15 of the participants received the drug within 2 hours after the echocardiography. We report no study violation. The study was stopped prematurely because of low recruitment.</p><p><strong>Conclusion: </strong>This pilot trial suggests that the success of a definitive randomized control trial to assess the efficacy of levothyroxine in deceased donors could benefit from a multicenter recruitment and education on the evidence surrounding the pharmacological management of organ donors. The need for consent to research interventions in deceased donors should also be clarified.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"261-268"},"PeriodicalIF":0.8,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1526924819855083","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40451843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donation after cardiac death for lung transplant: a case study.","authors":"Cyndy Kirschbaum","doi":"10.1177/152692481102100212","DOIUrl":"https://doi.org/10.1177/152692481102100212","url":null,"abstract":"<p><p>In late 2009, Gift of Life Michigan facilitated a donation after cardiac death lung recovery resulting in the first set of donation after cardiac death lungs to be utilized by a Michigan transplant center. Although placing lungs obtained via donation after cardiac death is more difficult because of a multitude of factors, the transplant coordinators, in conjunction with the transplant center, overcame several obstacles in order to transplant the lungs with good outcomes so far. Lung donation after cardiac death is becoming a more acceptable method of decreasing the length of the transplant waiting list as more data are becoming available.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"156-60"},"PeriodicalIF":0.8,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/152692481102100212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29989598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying and addressing barriers to African American and non-African American families' discussions about preemptive living related kidney transplantation.","authors":"L Ebony Boulware,&nbsp;Felicia Hill-Briggs,&nbsp;Edward S Kraus,&nbsp;J Keith Melancon,&nbsp;Mikiko Senga,&nbsp;Kira E Evans,&nbsp;Misty U Troll,&nbsp;Patti Ephraim,&nbsp;Bernard G Jaar,&nbsp;Donna I Myers,&nbsp;Raquel McGuire,&nbsp;Brenda Falcone,&nbsp;Bobbie Bonhage,&nbsp;Neil R Powe","doi":"10.1177/152692481102100203","DOIUrl":"https://doi.org/10.1177/152692481102100203","url":null,"abstract":"<p><strong>Context: </strong>Ethnic/racial minority and nonminority families' perceived barriers to discussing preemptive living related kidney transplantation (LRKT) and their views on the potential value of health care professionals trained to address barriers are unknown. OBJECTIVE, SETTING, AND PARTICIPANTS: To collect pilot data for evaluating perceived barriers to preemptive LRKT and to inform the development of a culturally sensitive intervention to improve families' consideration of LRKT. In 4 structured group interviews of African American and non-African American patients (2 groups) with progressing chronic kidney disease and their family members (2 groups), participants' perceived barriers to initiating LRKT discussions and their views regarding the value of social workers to support discussions were explored.</p><p><strong>Results: </strong>Patients' barriers included concerns about their (1) ability to initiate discussions, (2) discussions being misinterpreted as donation requests, (3) potential burdening of family members, (4) uncertainty about when to initiate discussions, and (5) inducing guilt or coercing family members. Family members' barriers included (1) feeling overwhelmed by patients' illness, (2) patients' denial about their illness, (3) caregiver stress, and (4) uncertainty about their own health or the health of other family members who might donate or need a kidney in the future. Participants reported that social workers could facilitate difficult or awkward discussions and help families understand the LRKT process, address financial concerns, and cope emotionally. Themes were similar between African Americans and non-African Americans.</p><p><strong>Conclusions: </strong>Families identified several barriers to discussing preemptive LRKT that could be addressed by social workers. Further research must be done to determine whether social workers need to tailor interventions to address families' cultural differences.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"97-104; quiz 105"},"PeriodicalIF":0.8,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/152692481102100203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29989817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transplant cost-report tracking at Henry Ford Transplant Institute and other centers nationwide.","authors":"Marianne Beach-Langlois,&nbsp;Pamela Yankasky","doi":"10.1177/152692481102100214","DOIUrl":"https://doi.org/10.1177/152692481102100214","url":null,"abstract":"<p><strong>Context: </strong>The lack of uniformity in the reporting of direct and indirect costs by organ acquisition cost centers, diagnosis-related groups, and in physician reimbursement often results in Medicare overpayment and findings of unjustified charges in audits conducted by the Office of the Inspector General. Although it is true that organ transplantation costs vary widely, uniform cost-report accounting is needed.</p><p><strong>Objective: </strong>Henry Ford Transplant Institute has developed systematic auditing protocols that result in acceptable compliance with Medicare. The differences between those protocols and the methods used elsewhere are illustrated by the results of a national survey of transplant centers.</p><p><strong>Design: </strong>The survey addresses 10 crucial questions, drawn from the cost-reporting model used at Henry Ford Transplant Institute. Setting-Surveys were distributed via the United Network for Organ Sharing listserv, with replies from 43 centers.</p><p><strong>Patients or other participants: </strong>The participants were transplant administrators.</p><p><strong>Results: </strong>Several important practices that are audited by the Office of the Inspector General were not followed by a number of reporting institutions. About 30% did not account for pretransplant charges, 15% did not track pretransplant services, 40% do not use an external consultant, and the frequency of physician time studies varied. On the other hand, the vast majority of institutions perform frequent time studies and manually review pretransplant charges. These results suggest that most centers use accounting methods similar to those used at Henry Ford Transplant Institute, which will significantly improve recognition of pretransplantation costs.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"169-73"},"PeriodicalIF":0.8,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/152692481102100214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29989600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Religious and ethnic influences on willingness to donate organs and donor behavior: an Australian perspective.","authors":"Claire E Wakefield,&nbsp;John Reid,&nbsp;Judi Homewood","doi":"10.1177/152692481102100213","DOIUrl":"https://doi.org/10.1177/152692481102100213","url":null,"abstract":"<p><strong>Context: </strong>Globally, the demand for donated organs outstrips supply, meaning that there are both practical and theoretical reasons for examining factors that are predictive of individuals' willingness to donate their organs upon their death.</p><p><strong>Objectives: </strong>To determine whether individuals of different religious denominations living in Australia have different views on organ donation, whether donation attitudes differ significantly across ethnic groups, and whether factors identified in international research are predictors of willingness to donate and actual donor behavior in this population.</p><p><strong>Participants: </strong>Data for this study were collected from students at an Australian university from a range of religious and ethnic backgrounds, and their friends and relatives (N = 509). Intervention-Participants were administered the Organ Donation Attitude Scale, as well as additional attitudes and knowledge measures.</p><p><strong>Main outcome measures: </strong>Self-reported \"willingness to donate\" and \"donor behavior\".</p><p><strong>Results: </strong>Our findings complemented those reported in comparable countries, with females, younger Australians, and those with high knowledge levels being more willing to donate than males, older persons, and those with low knowledge. Persons who described themselves as having stronger religious beliefs (particularly Buddhist and Islamic) held less favorable attitudes toward donation, had lower knowledge levels, and were more likely to oppose donation.</p><p><strong>Conclusions: </strong>Although this study established that attitudes toward, knowledge about, and predictors of organ donation in Australia are similar to those reported elsewhere, donation rates remain low. Further in-depth research examining the impact of religion and culture on attitudes, beliefs, and behavior is essential when exploring strategies to improve organ donation rates in highly multicultural societies such as Australia.</p>","PeriodicalId":346415,"journal":{"name":"Progress in Transplantation (Aliso Viejo, Calif.)","volume":" ","pages":"161-8"},"PeriodicalIF":0.8,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/152692481102100213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29989599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}