Food Chemistry Molecular Sciences最新文献_第2页

Phenolic extract from olive mill wastewater sustains mitochondrial bioenergetics upon oxidative insult 橄榄厂废水酚提取物维持线粒体生物能量氧化损伤。

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-12-11 DOI: 10.1016/j.fochms.2024.100234

Iolanda Rita Infantino , Salvatore Antonio Maria Cubisino , Stefano Conti Nibali , Paola Foti , Marianna Flora Tomasello , Silvia Boninelli , Giuseppe Battiato , Andrea Magrì , Angela Messina , Flora Valeria Romeo , Cinzia Caggia , Vito De Pinto , Simona Reina

{"title":"Phenolic extract from olive mill wastewater sustains mitochondrial bioenergetics upon oxidative insult","authors":"Iolanda Rita Infantino , Salvatore Antonio Maria Cubisino , Stefano Conti Nibali , Paola Foti , Marianna Flora Tomasello , Silvia Boninelli , Giuseppe Battiato , Andrea Magrì , Angela Messina , Flora Valeria Romeo , Cinzia Caggia , Vito De Pinto , Simona Reina","doi":"10.1016/j.fochms.2024.100234","DOIUrl":"10.1016/j.fochms.2024.100234","url":null,"abstract":"<div><div>In the last few years, many efforts have been devoted to the recovery and valorization of olive oil by-products because of their potentially high biological value. The olive mill wastewater (OMWW), a dark-green brown colored liquid that mainly consists of <em>olive</em> fruit vegetation water, is particularly exploited in this regard for its great content in phenolic compounds with strong antioxidant properties. In our previous work, we produced different OMWW fractions enriched in hydroxytyrosol- and hydroxytyrosol/oleuropein (i.e. C and OPE extracts, respectively) that exhibited considerable anti-microbial and radical-scavenging activities in vitro. Based on these findings, the present study aimed to assess the impact of C and OPE samples on mitochondrial function and oxidative stress response in mouse fibroblast-like cells (NCTC). Accordingly, OMWW phenolic extracts proved to enhance mitochondrial biogenesis and to reduce cellular sensitivity to hydrogen peroxide. Moreover, high-resolution respirometry experiments first time revealed the efficiency of OMWW phenols recovered by selective resin extraction in preventing mitochondrial respiration failure upon oxidative insult. Collected data definitely demonstrate the bioactivity of our phenolic-rich fractions, supporting the advantages of reusing the olive mill wastewater to generate, at low-cost, high added value molecules that could be useful for the improvement of health and nutrition products.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"10 ","pages":"Article 100234"},"PeriodicalIF":4.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11713508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrated transcriptomic and proteomic analyses provide insights into the biosynthesis of Lycii fructus polysaccharides from different cultivation regions 综合转录组学和蛋白质组学分析提供了对不同栽培地区枸杞多糖生物合成的见解。

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-12-05 DOI: 10.1016/j.fochms.2024.100232

Limei Tong , Yinxiu Jiang , Xinrun Zhang , Xia Zhang , Yihao Zheng , Qiheng Zhao , Sheng Yu , Wenhua Zhang , Gang Ren , Zhanping Chen , Yuling Zhao , Sheng Guo , Hui Yan , Shulan Su , Yang Pan , Jin-ao Duan , Fang Zhang

{"title":"Integrated transcriptomic and proteomic analyses provide insights into the biosynthesis of Lycii fructus polysaccharides from different cultivation regions","authors":"Limei Tong , Yinxiu Jiang , Xinrun Zhang , Xia Zhang , Yihao Zheng , Qiheng Zhao , Sheng Yu , Wenhua Zhang , Gang Ren , Zhanping Chen , Yuling Zhao , Sheng Guo , Hui Yan , Shulan Su , Yang Pan , Jin-ao Duan , Fang Zhang","doi":"10.1016/j.fochms.2024.100232","DOIUrl":"10.1016/j.fochms.2024.100232","url":null,"abstract":"<div><div>Polysaccharides from L. fructus (LFPs) serve as important active biomacromolecules for the wide spectrum of bioactivities exhibited by Lycii fructus. However, the influence of ecological environments on the biosynthesis and structural characteristics of LFPs remains largely unexplored. The present research conducted a comprehensive strategy combining physicochemical structural elucidation, stoichiometric analysis, transcriptomic profiling, and proteomic analysis in L. fructus samples collected from typical cultivation regions including Ningxia, Xinjiang, and Qinghai. The results revealed distinct structural variations in LFPs from Ningxia compared to those from other regions in terms of Glc, Ara, GalA composition percentages as well as overall content. The omics data identified 5531 and 8084 differentially expressed genes (DEGs), as well as 3728 and 4732 differentially expressed proteins (DEPs) in Xinjiang and Qinghai compared to Ningxia, respectively. The integration of transcriptomic and proteomic analyses revealed enrichment of DEGs and DEPs involved in the biosynthesis pathway of LFPs, including UDPs, AXS, and UGDH. Temperature and precipitation were the significant ecological factors affecting LFPs biosynthesis. These comprehensive analyses provide a novel perspective for explaining the important material basis and environmental response mechanism underlying the quality formation of L. fructus.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"10 ","pages":"Article 100232"},"PeriodicalIF":4.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolite differences and molecular mechanism between dehiscent and indehiscent capsule of mature sesame 成熟芝麻开裂与不开裂蒴果代谢差异及分子机制

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-11-26 DOI: 10.1016/j.fochms.2024.100231

Yinping Zhang , Ruirui Chen , Yujun Liu , Shuwen Xu , Shuguang Gao , Haiyang Zhang , Hongmei Miao , Lingling Qin , Xiangyu Zhou , Kiran Thakur , Cheng Li , Juan Li , Pengcheng Wei , Zhao-Jun Wei

{"title":"Metabolite differences and molecular mechanism between dehiscent and indehiscent capsule of mature sesame","authors":"Yinping Zhang , Ruirui Chen , Yujun Liu , Shuwen Xu , Shuguang Gao , Haiyang Zhang , Hongmei Miao , Lingling Qin , Xiangyu Zhou , Kiran Thakur , Cheng Li , Juan Li , Pengcheng Wei , Zhao-Jun Wei","doi":"10.1016/j.fochms.2024.100231","DOIUrl":"10.1016/j.fochms.2024.100231","url":null,"abstract":"<div><div>The loss of sesame capsule seed prior to harvest poses a significant economical challenge in mechanized production. The metabolites involved in capsule closure are still unclear. Using comparative metabolome and transcriptome analysis, this work investigated the molecular regulation and enrichment pathways in two sesame types of indehiscent capsule WanZhi28 (ND) and dehiscent capsule WanZhi2 (WZ2). The findings demonstrated that genes and metabolites were significantly enriched in lignin synthesis-related pathways. Furthermore, data suggests that lipid and sugar metabolism may have an impact on capsule closure. Apart from its function in cell signaling, the latter may contribute to the glycosylation of lignin monomers, while the former may provide ATP for cellular microtubule movement. This work concurrently focused on a large number of differentially expressed transcription factors linked to the sesame capsule's anti-cleft mechanism, providing new evidence for the discovery and use of functional markers and genes for capsule dehiscence. The identification of key pathways and regulatory mechanisms offers valuable information for developing strategies to mitigate seed loss during harvest, ultimately contributing to more efficient and profitable sesame production.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100231"},"PeriodicalIF":4.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcium chloride connects potato greening and enzymatic browning through salicylic acid 氯化钙通过水杨酸将马铃薯变绿和酶促褐变联系起来

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-11-22 DOI: 10.1016/j.fochms.2024.100229

Jingkui Shi , Wenxin Xie , Yanmei Sun , Qingyu Shi , Xin Xing , Qingguo Wang , Qingqing Li

{"title":"Calcium chloride connects potato greening and enzymatic browning through salicylic acid","authors":"Jingkui Shi , Wenxin Xie , Yanmei Sun , Qingyu Shi , Xin Xing , Qingguo Wang , Qingqing Li","doi":"10.1016/j.fochms.2024.100229","DOIUrl":"10.1016/j.fochms.2024.100229","url":null,"abstract":"<div><div>Greening and enzymatic browning are important factors causing post-harvest losses in potatoes. Although they are two different biological processes, there are some common inhibitors between them. Whether there is a correlation between the two has yet to be studies. In this research, we conducted transcriptome analysis of non-greening and greening potatoes, identifying several browning-related genes (polyphenol oxidase genes and peroxidase genes). Compared to non-greening potatoes, greening potatoes exhibited a greater browning degree. And calcium chloride (CaCl<sub>2</sub>) can inhibit both greening and enzymatic browning. However, the inhibitory effect on potatoes was weakened when treated simultaneously with SA synthesis inhibitor and CaCl<sub>2</sub>, indicating that CaCl<sub>2</sub> can regulate potato greening and browning by affecting internal SA synthesis. Additionally, exogenous SA treatment of potato tubers can also inhibit enzymatic browning. Our study not only demonstrated that CaCl<sub>2</sub> and SA can serve as a bridge connecting the potato greening and enzymatic browning, but also provided important references for the development of novel co-inhibitors.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100229"},"PeriodicalIF":4.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabonomic and transcriptomic profiling reveals amino acid metabolism affects the quality of premium japonica rice varieties in Northeast China 代谢组学和转录组学分析揭示氨基酸代谢对中国东北优质粳稻品种品质的影响

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-11-20 DOI: 10.1016/j.fochms.2024.100230

Jing Wang , Haitao Guan , Xiaolei Zhang , Changjun Dai , Cuiling Wang , Guofeng Chen , Kun Li , Zhenhua Xu , Ruiying Zhang , Baohai Liu , Hongtao Wen

{"title":"Metabonomic and transcriptomic profiling reveals amino acid metabolism affects the quality of premium japonica rice varieties in Northeast China","authors":"Jing Wang , Haitao Guan , Xiaolei Zhang , Changjun Dai , Cuiling Wang , Guofeng Chen , Kun Li , Zhenhua Xu , Ruiying Zhang , Baohai Liu , Hongtao Wen","doi":"10.1016/j.fochms.2024.100230","DOIUrl":"10.1016/j.fochms.2024.100230","url":null,"abstract":"<div><div>Rice consumption and demand for premium rice are increasing worldwide. However, the characterizations and how to identify the premium rice are still unclear. Small molecular metabolites have a great advantage in distinguishing subtle differences among similar agricultural products. So, we hypothesized that the metabolites would be the key to identifying the tiny differences in premium rice among similar varieties. In this study, we performed metabolomic and transcriptomic profiles to comprehensively elucidate key metabolites, genes, and formation mechanisms of premium rice. As a result, eight compounds belong to four categories, and 49 different expressional genes were identified in premium rice varieties after comparing with the second-best varieties. Moreover, the integrated analysis confirmed that the amino acid pathway, including 42 expression genes and 11 metabolites, was critical for the premium rice formation. Six genes and two metabolites had significant regulatory effects on the pathways. Furthermore, amino acid quantification confirmed the content of 12 kinds of hydrolytic amino acids, such as aspartic acid and arginine were different between premium and other varieties. These amino acids may serve as potential biomarkers for differentiating premium rice in Northeast China. Our results strongly support the possibility of differentiating premium rice and would provide essential data for premium rice identification and metabolomics-assisted breeding.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100230"},"PeriodicalIF":4.1,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of the aroma and flavor profiles of guava fruit (Psidium guajava) during developing by HS-SPME-GC/MS and RNA sequencing 通过 HS-SPME-GC/MS 和 RNA 测序表征番石榴果实（Psidium guajava）发育过程中的香气和风味特征

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-11-06 DOI: 10.1016/j.fochms.2024.100228

Jie Zhang , Yi Zhang , Shuaiyu Zou , Endian Yang , Ziyi Lei , Tingting Xu , Chen Feng

{"title":"Characterization of the aroma and flavor profiles of guava fruit (Psidium guajava) during developing by HS-SPME-GC/MS and RNA sequencing","authors":"Jie Zhang , Yi Zhang , Shuaiyu Zou , Endian Yang , Ziyi Lei , Tingting Xu , Chen Feng","doi":"10.1016/j.fochms.2024.100228","DOIUrl":"10.1016/j.fochms.2024.100228","url":null,"abstract":"<div><div>The flavor of guava, an important tropical fruit, is influenced by secondary metabolites. However, the mechanisms and processes underlying flavor formation in guava remain unclear. In this study, dynamic changes in volatile organic compounds (VOCs), sugars, and organic acids in guava peel and flesh across different developmental stages were investigated using headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC–MS) and high-performance liquid chromatography (HPLC). Here, we identified 90 VOCs, three sugars and eight organic acids. The dynamics of VOCs differ between the flesh and peel. The early developmental stages are more critical in influencing the variation of VOCs in the flesh, while VOC changes in peel occur more progressively across the developmental stages. By integrating transcriptomic and metabolomic analyses, we identified several key genes involved in VOC, sugar, and acid metabolism. This is the first study to describe the expression patterns of these genes throughout guava development, providing new insights into guava flavor development.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100228"},"PeriodicalIF":4.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142664059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on dynamic alterations of volatile organic compounds reveals aroma development over enzymatic-catalyzed process of Tieguanyin oolong tea production 酶催化铁观音乌龙茶生产过程中挥发性有机化合物动态变化揭示香气发展的研究

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-10-16 DOI: 10.1016/j.fochms.2024.100227

Liangyu Wu , Xiaolan Chen , Jiaqi Lin , Hongzheng Lin , Ningkai Liao , Chenxue Li , Yunfei Hu , Yun Sun

{"title":"Study on dynamic alterations of volatile organic compounds reveals aroma development over enzymatic-catalyzed process of Tieguanyin oolong tea production","authors":"Liangyu Wu , Xiaolan Chen , Jiaqi Lin , Hongzheng Lin , Ningkai Liao , Chenxue Li , Yunfei Hu , Yun Sun","doi":"10.1016/j.fochms.2024.100227","DOIUrl":"10.1016/j.fochms.2024.100227","url":null,"abstract":"<div><div>To elucidate the formation of characteristic aroma over enzymatic-catalyzed processes (ECP), GC–MS-based volatile-metabolomic combined with desorption-electrospray-ionization coupled mass-spectrometry-imaging (DESI-MSI) were employed to analyze the changes of volatile organic compounds (VOCs) in Tieguanyin tea. A total of 579 VOCs were obtained, from which 24 components involved in five pathways were identified as biomarkers. Among these, four VOCs including 2-furancarboxylic acid, 4-methylbenzaldehyde, N-benzylformamide, cuminaldehyde, were detected in both DESI-MSI and GC–MS analysis, exhibiting dynamic changes along processing steps. RNA-sequencing analysis indicated the genes referring to stress response were activated during tea processing, facilitating the accumulation of flora-fruity aroma in tea leaf. Metabolic pathways analysis revealed that the increase in floral-fruity related components such as volatile terpenoids, phenylpropanoids/benzenoids, indole, alongside a decrease in green leaf volatiles including (<em>E</em>)-2-Hexenal, (<em>Z</em>)-3-Hexenol, played a crucial role in development of characteristic aroma, which could be a feasible index for evaluating processing techniques or quality of oolong tea.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100227"},"PeriodicalIF":4.1,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waste to wealth: Polyhydroxyalkanoates (PHA) production from food waste for a sustainable packaging paradigm 变废为宝：利用食物垃圾生产聚羟基烷酸（PHA），打造可持续包装模式

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-10-10 DOI: 10.1016/j.fochms.2024.100225

Heri Septya Kusuma , Atna Sabita , Najla Anira Putri , Nadhira Azliza , Nafisa Illiyanasafa , Handoko Darmokoesoemo , Andrew Nosakhare Amenaghawon , Tonni Agustiono Kurniawan

{"title":"Waste to wealth: Polyhydroxyalkanoates (PHA) production from food waste for a sustainable packaging paradigm","authors":"Heri Septya Kusuma , Atna Sabita , Najla Anira Putri , Nadhira Azliza , Nafisa Illiyanasafa , Handoko Darmokoesoemo , Andrew Nosakhare Amenaghawon , Tonni Agustiono Kurniawan","doi":"10.1016/j.fochms.2024.100225","DOIUrl":"10.1016/j.fochms.2024.100225","url":null,"abstract":"<div><div>The growing demand for sustainable food packaging and the increasing concerns regarding environmental pollution have driven interest in biodegradable materials. This paper presents an in-depth review of the production of Polyhydroxyalkanoates (PHA), a biodegradable polymer, from food waste. PHA-based bioplastics, particularly when derived from low-cost carbon sources such as volatile fatty acids (VFAs) and waste oils, offer a promising solution for reducing plastic waste and enhancing food packaging sustainability. Through optimization of microbial fermentation processes, PHA production can achieve significant efficiency improvements, with yields reaching up to 87 % PHA content under ideal conditions. This review highlights the technical advancements in using PHA for food packaging, emphasizing its biodegradability, biocompatibility, and potential to serve as a biodegradable alternative to petroleum-based plastics. However, challenges such as high production costs, mechanical limitations, and the need for scalability remain barriers to industrial adoption. The future of PHA in food packaging hinges on overcoming these challenges through further research and innovation in production techniques, material properties, and cost reduction strategies, along with necessary legislative support to promote widespread use.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100225"},"PeriodicalIF":4.1,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma 维生素 E 在眼部健康中的应用：利用生育酚和生育三烯酚管理青光眼的全息方法

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-09-24 DOI: 10.1016/j.fochms.2024.100224

Fazira Latib Ratib, Muhamad Arif Irfan Zafendi, Mohd Aizuddin Mohd Lazaldin

{"title":"The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma","authors":"Fazira Latib Ratib, Muhamad Arif Irfan Zafendi, Mohd Aizuddin Mohd Lazaldin","doi":"10.1016/j.fochms.2024.100224","DOIUrl":"10.1016/j.fochms.2024.100224","url":null,"abstract":"<div><div>Vitamin E, encompassing tocopherols and tocotrienols is celebrated for its powerful antioxidant properties, which help neutralize free radicals and protect cells from oxidative damage. Over the years, research has shown that both tocopherols and tocotrienols offer significant benefits, including protection against radiation damage, cholesterol regulation, cardiovascular health, and neurological disorders. This wide range of benefits highlights the need for further exploration of vitamin E’s role in managing various diseases. One particularly promising area is its potential application in treating ocular diseases like glaucoma. Despite advances in treatment, current options have limitations, making the investigation of alternative approaches crucial. Omics technologies, which allow for a detailed examination of biological systems, could provide valuable insights into how tocopherols and tocotrienols work at a molecular level. Their neuroprotective and antioxidative properties make them promising candidates for glaucoma management. Additionally, the sustainability of vitamin E is noteworthy, as by-products from its production can be repurposed into valuable resources for nutraceuticals and pharmaceuticals. As research continues, integrating omics technologies with the study of vitamin E derivatives could unveil new therapeutic possibilities, further enhancing our understanding of its diverse health benefits and its potential role in preventing and managing diseases.</div></div>","PeriodicalId":34477,"journal":{"name":"Food Chemistry Molecular Sciences","volume":"9 ","pages":"Article 100224"},"PeriodicalIF":4.1,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142359324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combining widely targeted metabolomics and RNA-sequencing to reveal the function analysis of Phyllanthus emblica Linn. Juice-induced poultry macrophages 结合广泛的靶向代谢组学和RNA测序，揭示白花蛇舌草果汁诱导家禽巨噬细胞的功能分析果汁诱导的家禽巨噬细胞

IF 4.1

Food Chemistry Molecular Sciences Pub Date : 2024-09-22 DOI: 10.1016/j.fochms.2024.100223

Chenggang Liu, Jin jin, Binyi Sun

引用次数: 0