Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko最新文献_第4页

Biocompatible calcium-phosphate-collagen composite 生物相容性磷酸钙胶原复合材料

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-3-50-53

E. Budoragin, Vladimir N. Gorshenеv, Mariya S. Petcherskaya, M. V. Bambura, Maksim A. Dragun, V. Akopyan

引用次数: 0

A set of techniques to reduce the toxicity of radiation therapy for locally advanced rectal cancer 一套降低局部晚期直肠癌放射治疗毒性的技术

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-25-34

E. Petukhov, M. Chernykh, D. G. Ishchanov

{"title":"A set of techniques to reduce the toxicity of radiation therapy for locally advanced rectal cancer","authors":"E. Petukhov, M. Chernykh, D. G. Ishchanov","doi":"10.53652/2782-1730-2023-4-2-25-34","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-2-25-34","url":null,"abstract":"In order to reduce the incidence of acute radiation toxicity during chemoradiation therapy in patients with rectal cancer, we proposed a prone position for patient on the treatment table using a BellyBoard fixation device. The data on 156 patients with rectal cancer who underwent radiation therapy were analyzed, 108 patients were treated in prone position, 48 patients were treated in supine position. We obtained data on the reduction of small intestine volumes treated with the calculated dose of 35, 40 and 45 Gy (V35, V40 and V45) when positioning in the prone position compared to positioning in the supine position when contouring the volume of the small intestine in a single block (bowelbag). Treatment in the prone position using a BellyBoard fixation device significantly reduced acute urogenital toxicity (by 30%) and significantly reduced the incidence of grade 2 cystitis by 4 times (from 12% to 3%) compared with treatment of the patient in supine position. Treatment in the prone position using a BellyBoard significantly reduced the incidence of grade 3 enterocolitis by 5 times (from 10% to 2%) compared with treatment of the patient in supine position. Despite a number of objective advantages of using a BellyBoard fixation device, treatment in prone position is associated with a decrease in the reproducibility of patient positioning compared to supine position. The main source of error when using a BellyBoard is the unstable position of its aperture relative to the patient's anatomy. Treatment in prone position, planning using intensity-modulated radiation therapy (IMRT) and volume-modulated arc radiation therapy (VMAT), determining the indents during the conversion from the clinical target volume (CTV) to the planned target volume (PTV) based on the analysis of interfractional displacements, determining the optimal multiplicity of visual control may help to reduce the acute toxicity of chemoradiotherapy in patients with local advanced rectal cancer.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"95 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114050495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of treatment of gastric cancer in a patient with severe comorbidities 胃癌合并严重合并症的治疗1例

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-43-46

L. Levonyan, Devletkhan S. Temirkhanov

引用次数: 0

Some dystrophic diseases of the posterior pole of the eye associated with chronic inflammation and viral transmission (review) 眼球后极的一些营养不良疾病与慢性炎症和病毒传播有关(综述)

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-61-68

Sergej A. Ignatiev, V. A. Pavlov, Sergej P. Kazakov

{"title":"Some dystrophic diseases of the posterior pole of the eye associated with chronic inflammation and viral transmission (review)","authors":"Sergej A. Ignatiev, V. A. Pavlov, Sergej P. Kazakov","doi":"10.53652/2782-1730-2023-4-2-61-68","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-2-61-68","url":null,"abstract":"The medical and social urgency of the problem of age-related macular degeneration (AMD) and other degenerative diseases of the posterior pole of the eye is explained, first of all, by the fact that until now the disease is incurable and is characterized by a progressive course. AMD is one of the most common causes of vision loss. The incidence of AMD in Russia is 15 cases per 1,000 people. In the structure of primary AMD disability, patients of working age account for 21%, and due to the fact that there is a clear trend toward an increasing share of the elderly population, there is an annual increase in the incidence of AMD. In the last decade, pathological processes of the retina have become a global problem among people of different age categories, and this group of diseases includes a large number of different retinal dystrophies. In the last few years, there has been a clear trend towards the rejuvenation of such diseases. These changes are the most common causes of vision loss, especially the exudative form of age-related macular degeneration (AMD). Recent studies have shown that this form of AMD is associated not only with aging, vascular wall weakness and free-radical oxidation, but also with nonspecific immunostimulation and the potential role of cytomegalovirus infection, other viruses and microorganisms as a trigger agent. Not surprisingly, chronic infection of endothelial cells leads to the attraction of macrophages to the area of inflammation, their adhesion and synthesis of anti-inflammatory cytokines, which eventually stimulates the formation or activation of chorioidal neovascularization (CNV).","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116309765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibromuscular dysplasia: a review of the literature and case reports 纤维肌肉发育不良:文献和病例报告综述

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-2-5-11

A. Fursov, Nikolaj P. Potekhin, N. B. Lyapkova, Konstanin Yu. Gorodnichev

引用次数: 0

Сomparison of efficiency of methylene blue preparations for visualization of lymph drainage pathways in the experiment Сomparison实验中亚甲基蓝制剂对淋巴引流途径可视化的效率

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-2-12-17

V. Kovalenko, O. V. Barinov, E. E. Fufaev, I. V. Dmitrochenko, I. V. Kurakevich

{"title":"Сomparison of efficiency of methylene blue preparations for visualization of lymph drainage pathways in the experiment","authors":"V. Kovalenko, O. V. Barinov, E. E. Fufaev, I. V. Dmitrochenko, I. V. Kurakevich","doi":"10.53652/2782-1730-2022-3-2-12-17","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-2-12-17","url":null,"abstract":"Objective. To compare and evaluate the effectiveness of using methylene blue solutions to visualize lymph drainage pathways in laboratory animals (outbred rat). Materials and methods. In the experiment, 16 female outbred rats aged about 40 days, with an initial body weight of 180-220 g, kept in standard vivarium conditions, were used. Zolazepam (Zoletil®100) was used for anesthesia. Animals were randomized into 2 groups ― 8 in each. The first group was injected subcutaneously in the left thigh with a 1% aqueous solution of methylene blue, the second group ― solution of methylene blue with human serum albumin. Depending on the time of exposure, animals were divided randomly into 4 subgroups ― 15, 30, 45 and 60 minutes. There was evaluated the effectiveness of marking the lymph drainage pathways from the injection site. Results. The study demonstrated that the use of a 1% aqueous solution of methylene blue solution allows visualizing of the lymph drainage pathways when the preparation is exposed for 30 minutes. Staining of the lymph nodes of the next order occurs with an increase in exposure time. A solution of methylene blue in combination with human serum albumin stains the first node in the lymph drainage path 30 minutes after administration. The preparation is characterized by slow migration from the first-order lymph nodes (>60 minutes). Conclusion. The use of methylene blue solution in combination with serum albumin is characterized by slow migration from the first-order lymph nodes, which makes its use preferable for surgical interventions.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126895105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancement of external fixation as a foundation for innovative staged treatment of the wounded in the extremities 外固定支架的进展为四肢伤员的创新分阶段治疗奠定了基础

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-7-18

Dmitrij V. Trishkin, E. Kryukov, D. Davydov, V. Khominets, L. Brizhan', A. A. Kerimov

引用次数: 0

Peripheral cerebral aneurysms: clinical picture and diagnostics 脑外周动脉瘤:临床表现与诊断

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-1-39-47

Andrey M. Shitov, Il'ja A. Sazonov, O. Belousova, S. Eliava

引用次数: 0

Characteristics of medical implants 3D-printing 医用植入物3d打印的特点

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2021-2-4(6)-19-22

E. Budoragin, V. Gorshenev, V. Akopyan, M. V. Bambura, I. E. Budoragin

引用次数: 0

Features of clinical manifestations of coronary heart disease in patients with amiodarone-associated hypothyroidism 胺碘酮相关性甲状腺功能减退患者冠心病的临床表现特点

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-3-5-10

Sergej V. Chernavsky, A.V. Dorokhina, O. Artyushkevich, A. A. Stremoukhov, L.A. Kudentsova

{"title":"Features of clinical manifestations of coronary heart disease in patients with amiodarone-associated hypothyroidism","authors":"Sergej V. Chernavsky, A.V. Dorokhina, O. Artyushkevich, A. A. Stremoukhov, L.A. Kudentsova","doi":"10.53652/2782-1730-2022-3-3-5-10","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-3-5-10","url":null,"abstract":"Coronary heart disease (CHD) is an acute problem of modern medicine. Primarily, it is determined by the high prevalence of the disease among the working-age population, as well as by the considerable mortality and disability associated with it. Amiodarone (Am) is the drug of choice in the treatment of cardiac arrhythmias (CA), one of the frequent and threatening manifestations of CHD. Long-term use of the drug can lead to the development of primary hypothyroidism (HT), which significantly aggravates the course of cardiovascular diseases. Objective. To assess the cardiovascular system (CVS) of CHD patients with the development of amiodarone-associated hypothyroidism (AmHT). Material and methods. Analysis of case histories of 810 patients with CHD and various CA who were taking Am for sinus rhythm control was performed. The case histories were examined and a retrospective analysis was performed on the clinical course of CHD in 28 patients with AmHT before and after the development of thyreopathy. To evaluate the state of cardiovascular system the patients' complaints, objective examination data, electrocardiography (ECG) and echocardiography (EchoCG) were assessed. Results. Long-term intake of Am by patients with CHD results in primary HT in 3.4% of cases. The formation of thyreopathy significantly affects the course of the disease. Patients show a 19.6% increase in myocardial volume indices and a 22.7% decrease in myocardial contractility, with a 30.2% increase in left ventricular myocardial mass (LVMM). Conclusion. Amiodarone-associated hypothyroidism is one of the significant complications developing in patients taking the drug for a long period of time. The formation of thyreopathy in patients with CHD significantly aggravates the course of the underlying disease, which should be taken into account when prescribing treatment and dynamic monitoring","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132611576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0