Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko最新文献_第7页

Treatment of blind shrapnel wound with injury of the liver, left lung, diaphragm, and heart, complicated by intracardiac thrombosis and material embolism of the left common femoral artery 肝、左肺、横膈膜、心脏损伤并发心内血栓形成及左股总动脉物质栓塞的盲弹片伤的治疗

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-4-65-68

A. Fedorov, K. S. Zamskiy, Dmitrij V. Vinogradov, Dmitrij L. Kranin

引用次数: 0

Tendon-muscle transposition in severe irreversible damage to the radial nerve: surgical technique and clinical practice 桡神经严重不可逆损伤的肌腱-肌肉转位:手术技术与临床实践

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2021-2-4(6)-23-28

I.N. Isengaliev, V.D. Besedin, Yu V. Khrapov

引用次数: 0

Features of providing specialized surgical care for gunshot wounds of the neck with damage to hollow organs (larynx, trachea, pharynx, esophagus) 对颈部枪伤并空心器官(喉、气管、咽、食道)损伤提供专科外科护理的特点

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-4-69-78

S. I. Kubyshkin, Dmitrij V. Pyshnyi, E. Artemkin, Aleksej A. Sokolov, M. V. Onufrienko, Lyudmila S. Kharitonova, Yaroslav A. Khabazov

{"title":"Features of providing specialized surgical care for gunshot wounds of the neck with damage to hollow organs (larynx, trachea, pharynx, esophagus)","authors":"S. I. Kubyshkin, Dmitrij V. Pyshnyi, E. Artemkin, Aleksej A. Sokolov, M. V. Onufrienko, Lyudmila S. Kharitonova, Yaroslav A. Khabazov","doi":"10.53652/2782-1730-2022-3-4-69-78","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-4-69-78","url":null,"abstract":"The objective of this work is to share our experience in providing specialized surgical care to patients coming from stages of medical evacuation with wounds of hollow neck organs. A special military operation (SMO) takes place in an environment different from previous local wars. The nature of military operations and the saturation of the enemy's armed forces with new types of weapons gave a significantly higher number of wounded than previous local conflicts. The predominance of mine-explosive shrapnel wounds, different time intervals from injury to getting to the stage of specialized medical care for wounded with already existing purulent complications of gunshot wounds are the features of the SMO. Wounded with injuries of the hollow organs of the neck, entering the MMCH named after N.N. Burdenko from 3 to 6 days after injury, with already developed purulent complications, require comprehensive intensive therapy and participation in the treatment of specialists of various surgical specialties. An integrated approach with the compliance with the regulations of military-field surgery using new methods of diagnostics and treatment of wounds can improve the effectiveness of therapy and reduce the number of lethal outcomes. This article discusses diagnostic and treatment algorithms for different variants of neck wounds. The experience of the described cases of successful treatment of wounded with injuries of the hollow organs of the neck shows the possibilities of MMCH named after N.N. Burdenko in treatment using various methods, and can be useful to doctors of both the Ministry of Defense and the Ministry of Health of the Russian Federation.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114690518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aspects of stem cell autotransplantation treatment in patients with multiple myeloma 多发性骨髓瘤患者干细胞自体移植治疗的几个方面

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2021-2-4(6)-38-44

I. Kostroma, Z. Sidorova, N. Semenova, E. Stepchenkova, S. Gritsaev

{"title":"Aspects of stem cell autotransplantation treatment in patients with multiple myeloma","authors":"I. Kostroma, Z. Sidorova, N. Semenova, E. Stepchenkova, S. Gritsaev","doi":"10.53652/2782-1730-2021-2-4(6)-38-44","DOIUrl":"https://doi.org/10.53652/2782-1730-2021-2-4(6)-38-44","url":null,"abstract":"The effectiveness of multiple myeloma (MM) patients’ treatment is dependent in particular on the depth of response after autologous stem cell transplantation (аutoHSCT). The importance of predictors associated with the quality of response after аutoHSCT is due to the possibility of changing the intensity of some stage of transplantation. The aim of the study was to determine the incidence of cases without the improvement of response depth after autoHSCT and to evaluate the distribution of genotype of a number of genes and status of hemopoietic niche cells as a possible predictor of аutoHSCT effectiveness in MM patients. Retrospective analysis of 84 MM patient’s data was carried out. Total number of transplants performed was 112 including 84 first and 28 second transplants. The response was determined according to IWG criteria. Status of hemopoietic niche cells was evaluated by histological, immunohistochemistry and morphometric methods. Improvment of the response depth after the first аutoHSCT was recorded in 29 (54.7%) patients. Similar events were higher in the patients with previous VGPR: 57.9% vs 18.2% in patients with PR; p=0.005. There was no difference in other clinical and hematologic parameters between the groups. After the second аutoHSCT the variant of response did not change in 4 out of 6 patients. The deepening of response occurred significantly more often in cases with more cells localized on endost; p=0.038. The results of bone marrow trepanobiopsy can be considered as predictors of a possible improvement in the quality of response or lack thereof in patients with MM after performing аutoHSCT.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132147334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modern principles of endoscopic transnasal reconstruction of skull base defects Literature review 内镜下经鼻颅底缺损重建术的现代原理文献综述

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-3-54-58

I. Chernov, Valerij E. Chernov

引用次数: 0

Аnalysis of the duration and intensity of the humoral immune response in medical workers after COVID-19 COVID-19后医务人员体液免疫反应的持续时间和强度Аnalysis

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2021-2-4(6)-29-37

S. Kazakov, N. Davydova, S. Putkov, D. Reshetnyak, I.V. Aristarchova

{"title":"Аnalysis of the duration and intensity of the humoral immune response in medical workers after COVID-19","authors":"S. Kazakov, N. Davydova, S. Putkov, D. Reshetnyak, I.V. Aristarchova","doi":"10.53652/2782-1730-2021-2-4(6)-29-37","DOIUrl":"https://doi.org/10.53652/2782-1730-2021-2-4(6)-29-37","url":null,"abstract":"The article presents data on the duration and intensity of the humoral immune response in medical workers who had COVID-19 in the first wave of the pandemic. The response was analyzed based on the production of immunoglobulin M (IgM) and G (IgG) antibodies to SARS-CoV-2. Using ELISA immunoassay systems manufactured by «Vector-Best» (Novosibirsk, RF) and foreign test systems based on immunofluorescence analysis by Abbott (USA), a comparative assessment of the production of antibodies to SARS-CoV-2 was carried out. The presented semi-quantitative and quantitative data on IgM and IgG antibodies to SARS-CoV-2 in dynamics for the period from May 2020 to May 2021 in medical workers who had had COVID-19. The difference in the antibodies’ detection and the dynamics of their decrease depending on the type of antibodies detected are shown. Data on the frequency of occurrence of IgM antibodies to SARS-CoV-2 in medical workers who had had COVID-19 during the observed period are presented, with the assumption of reinfection or persistence of the virus. Data are presented on the number of IgG antibodies expressed in international units (BAU/ml) and the relative number of patients who managed to maintain different (150/300/590 BAU/ml) protective levels of antibodies to SARS-CoV-2 over the observed period, including those with a minimum level of protection by the minimum titer of neutralizing antibodies.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114413476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Traumatic cerebral aneurysm after penetrating gunshot wound of the brain 脑部穿透枪伤后的创伤性脑动脉瘤

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-35-42

K. Babichev, Aleksandr V. Savello, D. V. Svistov

引用次数: 1

Application of cellular technologies in the treatment of chronic pain ofthe lumbar spine 细胞技术在腰椎慢性疼痛治疗中的应用

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-1-43-49

S. Kudryakov, D. A. Najda, G. N. Kozlov

{"title":"Application of cellular technologies in the treatment of chronic pain ofthe lumbar spine","authors":"S. Kudryakov, D. A. Najda, G. N. Kozlov","doi":"10.53652/2782-1730-2022-3-1-43-49","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-1-43-49","url":null,"abstract":"The paper presents the results of clinical testing of autologous cells of the stromal vascular fraction (SVF) mesenchymal stromal cells in patients with deforming spondyloarthrosis of the lumbar spine. The study selected 20 patients aged 45 to 85 years with symptoms of degenerative spondyloarthrosis of the lumbar spine confirmed by radiological methods (CT, MRI, X-ray), 5 men, 15 women, average age 64.7 years with a disease duration of 5 years. Autologous SVF cells were injected into the affected facet joints under the control of an electron optical converter. The introduction of SVF cells did not cause the development of inflammatory allergic and toxic reactions. Patient survey conducted 1 month after the introduction of SVF cells revealed a decrease in the severity of pain syndrome, assessed on a visual analog scale (VAS) and a specialized SF-36 scale (p<0.05 on both scales). Patients noted an improvement in functional activity and quality of life associated with the affected facet joints. Positive clinical dynamic was maintained during follow-up up to 6 months. The control magnetic resonance imaging after 6 months revealed no significant differences from the initial examination. Our study showed the safety and good tolerability of the introduction of autologous SVF cells into the areathe zygapophysial (facet) of facet joints. Our study showed the safety and good tolerability of the introduction of autologous SVF cells into the area of the Lumbar Facet Joint Injectionsin patients with severe manifestations of deforming spondyloarthrosis. The obtained results also indicate a significant anti-inflammatory effect of autologous SVF cells of adipose tissue at the early stages of cell therapy.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131670086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prospects for the use of respiratory exercisers in patients with traumatic injuries 呼吸锻炼器在创伤性损伤患者中的应用前景

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2023-4-2-55-60

D. V. Frolov, Andrej A. Zajcev, M. A. Shchedrina

{"title":"Prospects for the use of respiratory exercisers in patients with traumatic injuries","authors":"D. V. Frolov, Andrej A. Zajcev, M. A. Shchedrina","doi":"10.53652/2782-1730-2023-4-2-55-60","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-2-55-60","url":null,"abstract":"Chest injuries sustained during armed conflict have a high mortality rate and are accompanied by pulmonary dysfunction. Pulmonary contusion is manifested by rupture of pulmonary parenchyma, atelectasis, and hemorrhages in pulmonary parenchyma. The treatment strategy for such patients includes anesthesia, management of acute respiratory failure, treatment of infectious complications, sanation of airways, and rehabilitation measures. One of the goals of such interventions is the elimination of respiratory biomechanics disorders. It is recommended to use respiratory exercisers with a threshold level of resistance for the process of inhalation and exhalation to train respiratory muscles. At the Main Military Clinical Hospital named after N.N. Burdenko the possibility of application of the respiratory simulator \"Universal-2011\" as a therapeutic physical training tool in the hospital phase of treatment of patients with thoracic trauma was studied. The efficacy of the carried activities was evaluated by functional tests of tolerance to hyper- and hypocapnia of Stange and Gench and the assessment of thoracic cage excursion. The experience of using a respiratory exerciser was observed to be positive. All 25 patients fulfilled the planned program with the achievement of improvement of external respiratory function and exercise tolerance.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132306425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymer biodegradable fixators in the treatment of near- and intra articular fractures 聚合物可生物降解固定物在治疗关节内骨折中的应用

Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko Pub Date : 1900-01-01 DOI: 10.53652/2782-1730-2022-3-1-15-25

Aleksej M Fajn, A. Vaza, E. Mamatov, E. A. Zhirkova, Sergej F Gneteckij, R. Titov, K. I. Skuratovskaya

{"title":"Polymer biodegradable fixators in the treatment of near- and intra articular fractures","authors":"Aleksej M Fajn, A. Vaza, E. Mamatov, E. A. Zhirkova, Sergej F Gneteckij, R. Titov, K. I. Skuratovskaya","doi":"10.53652/2782-1730-2022-3-1-15-25","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-1-15-25","url":null,"abstract":"We have observed an increase in the number of patients with intra-articular fractures, as well as in the severity of such fractures. Traditionally, metal implants such as wires, capless screws, Herbert screws are used for osteosynthesis of intra-articular fractures with small bone and cartilage fragments. However, the metal implants have their drawbacks. Biodegradable fixatives (BDF) made from a copolymer of polylactic and polyglycolic acids (PLGA) could be an alternative to the implants. Two groups of 132 people with intra-articular fractures of different localization were formed, biodegradable implants were used in the main group, metal implants were used in the control group. The groups were correlated by sex, age and nature of fractures. We compared the time spent in the operating room for similar operations, the number of operations to remove the fixators in both groups, and the number of complications. Compared functional outcomes. We assessed the possibility of interpreting MSCT and MRI data in the isolated use of BDF. In the group with the use of biodegradable implants, fewer removal operations were required (44%) than in the group without the use of biodegradable implants (58%), which is statistically significant. Complications developed in the main group amounted to 3% (4 cases), while in the group with metal implants they amounted to 10% (13 cases). We have found that the use of biodegradable implants has satisfactory clinical results, a low percentage of implant removal operations, and lower complications rate.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128802301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0