A.V. Tsapir, Maria Yu. Pitkevich, Aleksej V. Smolin, Vladislav Ju. Kosyrev, A. A. Vologdin
{"title":"Neoadjuvant immunotherapy in the treatment of squamous cell carcinoma of the head and neck","authors":"A.V. Tsapir, Maria Yu. Pitkevich, Aleksej V. Smolin, Vladislav Ju. Kosyrev, A. A. Vologdin","doi":"10.53652/2782-1730-2023-4-1-63-71","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-1-63-71","url":null,"abstract":"Head and neck tumors are among the ten most common neoplasms both in the world and in Russia [1]. In 64% of cases, squamous cell carcinoma of the head and neck is first diagnosed at the stage of a locally spread process. The emergence of new equipment for radiation therapy, new irradiation techniques such as VMAT, IMRT, better visualization, positioning of the patient and the emergence of new methods of drug treatment have allowed to increase the duration and quality of life of patients. However, even with such treatment approaches, the 5-year overall survival rate is only 50% [11]. The effectiveness of immunotherapy in patients with advanced squamous cell carcinoma of the head and neck and unsatisfactory results of surgical treatment of operable stages have set the ground for active study of neoadjuvant therapy [11]. In the available literature, we found that neoadjuvant immunotherapy for squamous cell carcinoma of the head and neck has already demonstrated its effectiveness in preliminary clinical studies, which makes it a promising direction for further study and implementation in the daily practice of an oncologist","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121889383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramis A. Aslanov, A. K. Dulaev, D. Kutyanov, Z. Y. Alikov
{"title":"A new method for shortsegment multi-rod posterior instrumental fixation of lumbar vertebral body fractures: development of the technology and a clinical case","authors":"Ramis A. Aslanov, A. K. Dulaev, D. Kutyanov, Z. Y. Alikov","doi":"10.53652/2782-1730-2023-4-2-47-54","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-2-47-54","url":null,"abstract":"A new method of short segmental multi-rod posterior instrumental fixation of lumbar vertebral body fractures (groups A3 and A4 according to the AO classification) characterized by the combined use of two short transpedicular screws with maximum lateralization of their heads fixing the injured and adjacent vertebrae and two short laminar implants in the form of distractors and contractors installed according to a standard technique with their positioning symmetrically to the spinous processes was developed. If transpedicular fixation of the fractured vertebra is impossible, both laminar systems are installed in the form of staples with circular coverage of the corresponding half-arc of the adjacent vertebrae due to supra- and infralaminar arrangement of standard hooks. The method involves the use of standard vertebrological instruments as well as widely available licensed implants and the classic technique of their installation. A clinical case of surgical treatment of a 27-year-old victim with a comminuted compression fracture (group A3 according to the AO classification) of the 3rd lumbar vertebra is reported. An excellent clinical and radiological result was obtained.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129022957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Lamotkin, D. Korabelnikov, Elena G. Perevalova, A. Lamotkin
{"title":"Dermatoscopic characterization of various vascular signs in skin tumors","authors":"I. Lamotkin, D. Korabelnikov, Elena G. Perevalova, A. Lamotkin","doi":"10.53652/2782-1730-2023-4-1-12-21","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-1-12-21","url":null,"abstract":"The authors considered the dermatoscopic vascular signs most frequently encountered in the practice of dermatologists, cosmetologists and oncologists in melanocytic and non-melanocytic skin tumors. The paper presents modern views on dermatoscopic diagnosis of skin tumors. Based on clinical experience and data from the literature, dermatoscopic features that occur in various melanocytic and non-melanocytic skin tumors are identified.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116143420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biportal endoscopic surgery for degenerative diseases of the lumbar spine","authors":"V. Pereverzev, V. V. Shvets, Nadezhda A Chernova","doi":"10.53652/2782-1730-2022-3-1-63-70","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-1-63-70","url":null,"abstract":"Biportal endoscopic surgery is a minimally invasive innovative method of treatment, where two ports are used, one for visualization, the other for surgical instruments. In this article we describe the biportal endoscopic technique for laminectomy and discectomy, as well as discuss the features of these interventions in degenerative diseases of the spine.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130129854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extracorporeal detoxification in intensive care of metabolic acidosis in cancer patients","authors":"E. Gromova","doi":"10.53652/2782-1730-2022-3-2-44-47","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-2-44-47","url":null,"abstract":"Metabolic acidosis is a satellite and a consequence of a number of damaging factors; it belongs to the category of critical pathological conditions, associated with high mortality, and requires appropriate intensive therapy. In cancer patients, the risk of decompensated homeostasis disorders is significantly higher compared to the general population of patients, which reduces the possibility of antitumor treatment and worsens the prognosis. Timely application of extracorporeal detoxification allows to avoid fatal complications and continue antitumor treatment.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130902435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadezhda A Veremeenko, Arina V Saukina, Svetlana A Perepelica
{"title":"Integration of virtual reality into the program of non-drugtreatment of pain and early rehabilitation","authors":"Nadezhda A Veremeenko, Arina V Saukina, Svetlana A Perepelica","doi":"10.53652/2782-1730-2022-3-1-5-14","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-1-5-14","url":null,"abstract":"The article deals with the issues of non-drug treatment of pain from the standpoint of a biopsychosocial approach using virtual reality (VR) as well as the possibility ofintegrating this methodinto an early rehabilitation program for neurological patients. The historical aspects of discovery and integration of VRinto medicine and the results of using the method to reduce the intensity of pain in patients with burn disease the possibility of using VR technology in anesthesiology and resuscitation as an alternative to narcotic analgesics for certain types of intervention are presented The use of VR is promising in the motorand cognitive rehabilitation ofpatients with various pathologies ofthe central nervous system and can be used at any stage of rehabilitation at low financial costs with minimal involvement ofmedical personnel in the hospital and outpatient settings.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130430826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abduhalim R Raimzhanov, Bahtiyar S Atabaev, Sherbet K Zhusupova
{"title":"Results of autologous peripheral hematopoietic stem cell transplantation in multiple myeloma in Kyrgyzstan","authors":"Abduhalim R Raimzhanov, Bahtiyar S Atabaev, Sherbet K Zhusupova","doi":"10.53652/2782-1730-2022-3-1-26-32","DOIUrl":"https://doi.org/10.53652/2782-1730-2022-3-1-26-32","url":null,"abstract":"The article is devoted to performing a series of autologous transplantations of peripheral hematopoietic stem cells in multiple myeloma (MM). For the first time in Central Asia, in the Kyrgyz Scientific Center of Hematology of the Ministry of Health of the Kyrgyz Republic, autologous hematopoietic stem cells were used in the treatment of 26 patients with MM. Comprehensive laboratory and functional analyses were carried out to diagnose MM. Autologous stem cells were collected using the blood cell separator. Conditioning mode and an algorithm of therapeutic approaches of patients before autotransplantation and post-transplantation monitoring were used.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125324602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. P. Chuprina, S. Y. Polushin, K. Zamsky, E. Vinogradov
{"title":"A case of successful treatment of a patient with splenic artery aneurysm, splenic vein malformation and splenomegaly","authors":"A. P. Chuprina, S. Y. Polushin, K. Zamsky, E. Vinogradov","doi":"10.53652/2782-1730-2023-4-1-48-54","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-1-48-54","url":null,"abstract":"The clinical picture, diagnosis and selected option of surgical treatment of splenic artery aneurysm with splenic vein malformation and splenomegaly in a 30-year-old patient are discussed.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123203217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. A. Putintsev, Jurij E. Loginov, Shamil' Ch. Gizatullin, Dmitrij V. Bogomolov, P. Dzhuvalyakov, O. Romanova
{"title":"Forensic medical examination of military personnel with postcommotion syndrome as a result of combat trauma","authors":"V. A. Putintsev, Jurij E. Loginov, Shamil' Ch. Gizatullin, Dmitrij V. Bogomolov, P. Dzhuvalyakov, O. Romanova","doi":"10.53652/2782-1730-2023-4-2-77-82","DOIUrl":"https://doi.org/10.53652/2782-1730-2023-4-2-77-82","url":null,"abstract":"The article represents the basic principles of forensic and forensic-psychiatric examination of servicemen in order to determine the severity of damage to human health in case of craniocerebral trauma as a consequence of combat trauma resulting in mental disorder – post-commotion syndrome.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121396294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L.V. Ermokhina, N. V. Ermokhina, A. Zavarzin, V. Stets
{"title":"A variant of anesthesia for total arthroplasty of the lower extremity joints","authors":"L.V. Ermokhina, N. V. Ermokhina, A. Zavarzin, V. Stets","doi":"10.53652/2782-1730-2021-2-4(6)-05-11","DOIUrl":"https://doi.org/10.53652/2782-1730-2021-2-4(6)-05-11","url":null,"abstract":"In this study we sought to optimize analgesia in total joint arthroplasty of the lower extremity and reduce the risk of arterial hypotension in patients with various degrees of obesity. The optimization contributed to the development of a new technique of spinal anesthesia. The technique leads to the epidural volume extension, as well as the decrease of local anesthetic doses administered into the subarachnoid space and saving the level of sensory block. The aim of the study was to study the effect of the spinal anesthesia with the epidural volume extension technique on the level of sensory block and hemodynamics in patients with various degrees of obesity during total arthroplasty of the lower extremity joints for III stage osteoarthritis. The prospective single-center study included 103 patients (79 men (76.7%), mean age 59±11 years, range from 33 to 74 years) who were treated in the Department of Traumatology and Orthopedics from September 2019 to May 2020. Anthropometric parameters, levels of sensory and motor blocks, level of pain syndrome, sympathetic block, duration of surgery and anesthesia were analyzed. To assess the impact of all factors on the outcome, methods of one-dimensional analysis with the calculation of relative risk (RR) were used. All patients were divided into two groups: the control group (combined spinal-epidural anesthesia was used) and the main group (spinal anesthesia with epidural volume extension was used). The average upper level of the sensor block (Th-segment) at 15 minutes after spinal anesthesia did not significantly differ in the groups (p=0.95). Differences in the frequency of hypotension in the groups were not statistically significant (p˃0.05). RR: 1.17 [95% CI: 0.794; 1.726]. Reducing the dose of a local anesthetic by 25% to provide adequate spinal anesthesia with the epidural volume extension in patients with a high body mass index achieves the same result when assessing sensory, motor and sympathetic blockages when compared with the traditional method of anesthesia.","PeriodicalId":344630,"journal":{"name":"Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126823649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}