{"title":"Ethosomes and their monotonous effects on Skin cancer disruption","authors":"Prafull Shinde, A. Page, Sankha Bhattacharya","doi":"10.3389/fnano.2023.1087413","DOIUrl":"https://doi.org/10.3389/fnano.2023.1087413","url":null,"abstract":"Skin cancer is one of the most prominent diseases, affecting all continents worldwide, and has shown a significant rise in mortality and prevalence. Conventional therapy, including chemotherapy and surgery, has a few drawbacks. The ethosomal systems would be thoroughly reviewed in this compilation, and they would be classified based on constituents: classical ethosomes, binary ethosomes, and transethosomes. Ethosomes systems are model lipid vesicular carriers with a substantial portion of ethanol. The impacts of ethosomal system components, preparation techniques, and their major roles in selecting the final characteristics of these nanocarriers are comprehensively reviewed in this chapter. The special techniques for ethosomes, including the cold approach, hot approach, injection method, mechanical dispersion method, and conventional method, are explained in this chapter. Various evaluation parameters of ethosomes were also explained. Furthermore, ethosomal gels, patches, and creams can be emphasised as innovative pharmaceutical drug formulations. Some hybrid ethosomal vesicles possessing combinatorial cancer therapy using nanomedicine could overcome the current drug resistance of specific cancer cells. Through the use of repurpose therapy, phytoconstituents may be delivered more effectively. A wide range of in vivo models are employed to assess their effectiveness. Ethosomes have provided numerous potential skin cancer therapeutic approaches in the future.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41599358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Viscosity dissipation and mixed convection flow in a vertical double-passage channel with permeable fluid","authors":"I. Athal, I. Sarris, Palani Velusamy, V. Govindan","doi":"10.3389/fnano.2022.1058973","DOIUrl":"https://doi.org/10.3389/fnano.2022.1058973","url":null,"abstract":"The method of regular perturbation is used to analyse the fully developed flow and heat transfer in a vertical two-way channel containing a permeable liquid. The Brinkman model is used for flow through porous media. The energy equation contains a viscosity term and a Darcy dissipation term. The fully conductive thin partition is divided into two stages; the wall is uniformly heated; and the effects of the porous parameter σ and the mixed convection parameter λ on the velocity and temperature distribution near the hot and cold walls are investigated. The results show that these effects mainly depend on the position of the baffle. Analytical solutions are first used to resolve the simpler problems of either a negligible Brinkman number or a negligible Grashof number. Then, using a perturbation series method, the combined effects of buoyant forces and viscous dissipation are examined. The velocity field and the temperature field in the cases under study were assessed.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42369736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current and future prospects of “all-organic” nanoinsecticides for agricultural insect pest management","authors":"Sourav Manna, Sampurna Roy, Avishek Dolai, Arunreddy Ravula, Venkatesan Perumal, Amlan Das","doi":"10.3389/fnano.2022.1082128","DOIUrl":"https://doi.org/10.3389/fnano.2022.1082128","url":null,"abstract":"With the popularity of nanotechnology, the use of nanoparticles in pest management has become widespread. Nanoformulated pesticides have several advantages over conventional pesticide formulations, including improved environmental stability, controlled release of active ingredients, increased permeability, targeted delivery, etc. Despite these advantages, recent research shows that several nanoparticles used in conventional nanopesticide formulations can be toxic to crops and beneficial organisms due to bioaccumulation and trophic transfer. Therefore, traditional nanopesticides are thought to be non-advantageous for “green agriculture”. In assessing the current situation, developing “all-organic” nanopesticides could be the next-generation weapon for reducing the adverse impact of traditional nanopesticides. However, their formulation and application knowledge is remarkably limited. The green synthesis of “all-organic” nanoparticles makes them more environmentally friendly than conventional nanopesticides due to their minimal residual and hazardous effects. This review focuses on the current development scenario of “all-organic” nanopesticides, their advantages, and potential effects on target organisms compared to traditional nanopesticides. Graphical Abstract","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47165511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The emerging significance of nanomedicine-based approaches to fighting COVID-19 variants of concern: A perspective on the nanotechnology’s role in COVID-19 diagnosis and treatment","authors":"C. K. Singh, K. K. Sodhi","doi":"10.3389/fnano.2022.1084033","DOIUrl":"https://doi.org/10.3389/fnano.2022.1084033","url":null,"abstract":"COVID-19, one of the worst-hit pandemics, has quickly spread like fire across nations with very high mortality rates. Researchers all around the globe are making consistent efforts to address the main challenges faced due to COVID-19 infection including prompt diagnosis and therapeutics to reduce mortality. Conventional medical technology does not effectively contain the havoc caused by deadly COVID-19. This signals a crucial mandate for innovative and novel interventions in diagnostics and therapeutics to combat this ongoing pandemic and counter its successor or disease if it were ever to arise. The expeditious solutions can spring from promising areas such as nanomedicine and nanotechnology. Nanomedicine is a dominant tool that has a huge potential to alleviate the disease burden by providing nanoparticle-based vaccines and carriers. Nanotechnology encompasses multidisciplinary aspects including artificial intelligence, chemistry, biology, material science, physical science, and medicine. Nanoparticles offer many advantages compared to larger particles, including better magnetic properties and a multiplied surface-to-volume ratio. Given this, the present review focuses on promising nanomedicine-based solutions to combat COVID-19 and their utility to control a broad range of pathogens and viruses, along with understanding their role in the therapy, diagnosis, and prevention of COVID-19. Various studies, reports, and recent research and development from the nanotechnology perspective are discussed in this article.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46328606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical study of magneto-optical binding between two dipolar particles under illumination by two counter-propagating waves","authors":"R. M. Abraham-Ekeroth","doi":"10.3389/fnano.2023.1134850","DOIUrl":"https://doi.org/10.3389/fnano.2023.1134850","url":null,"abstract":"Introduction: The formation of a stable magneto plasmonic dimer with THz resonances is theoretically studied for the principal directions of the system. Unlike a recent report, our work provides a complete description of the full photonic coupling for arbitrary magnetic fields as, for instance, unbalanced particle spins. Methods: As an illustration, we consider two small, n-doped InSb nanoparticles under illumination by two counter-propagating plane waves. Results: Remarkably, when an external magnetic field exists, the symmetry in the system is broken, and a resonant radiation pressure for the dimer appears. Similarly, tunable inter-particle forces and spins are exerted on the non-reciprocal dimer. The system is also characterized when the magnetic field is absent. Moreover, we show how the mechanical observables truly characterize the dimer since their resonance dependency contains detailed information about the system. Discussion: Unlike far-field observables like absorption, mechanical magnitudes depend on the system's near-field. In addition, the nature of the particle spins is originally explained by the energy flow's behavior around the dimer. This work constitutes a generalization of any previous approach to optical binding between small nanoparticles. It paves the way for fully controlling optical matter and nano factory designs based on surface plasmon polaritons.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44626158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Rengifo, M.H. Aguirre, M. Sirena, U. Lüders, D. Rubi
{"title":"Epitaxial ferroelectric memristors integrated with silicon","authors":"Miguel Rengifo, M.H. Aguirre, M. Sirena, U. Lüders, D. Rubi","doi":"10.3389/fnano.2022.1092177","DOIUrl":"https://doi.org/10.3389/fnano.2022.1092177","url":null,"abstract":"Neuromorphic computing requires the development of solid-state units able to electrically mimic the behavior of biological neurons and synapses. This can be achieved by developing memristive systems based on ferroelectric oxides. In this work we fabricate and characterize high quality epitaxial BaTiO3-based memristors integrated with silicon. After proving the ferroelectric character of BaTiO3 we tested the memristive response of LaNiO3/BaTiO3/Pt microstructures and found a complex behavior which includes the co-existence of volatile and non-volatile effects, arising from the modulation of the BaTiO3/Pt Schottky interface by the direction of the polarization coupled to oxygen vacancy electromigration to/from the interface. This produces remanent resistance loops with tunable ON/OFF ratio and asymmetric resistance relaxations. These properties might be harnessed for the development of neuromorphic hardware compatible with existing silicon-based technology.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43704706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Hussain, Naveed Qasim Abro, N. Ahmed, S. Memon, Najma Memon
{"title":"Nano-antivirals: A comprehensive review","authors":"F. Hussain, Naveed Qasim Abro, N. Ahmed, S. Memon, Najma Memon","doi":"10.3389/fnano.2022.1064615","DOIUrl":"https://doi.org/10.3389/fnano.2022.1064615","url":null,"abstract":"Nanoparticles can be used as inhibitory agents against various microorganisms, including bacteria, algae, archaea, fungi, and a huge class of viruses. The mechanism of action includes inhibiting the function of the cell membrane/stopping the synthesis of the cell membrane, disturbing the transduction of energy, producing toxic reactive oxygen species (ROS), and inhibiting or reducing RNA and DNA production. Various nanomaterials, including different metallic, silicon, and carbon-based nanomaterials and nanoarchitectures, have been successfully used against different viruses. Recent research strongly agrees that these nanoarchitecture-based virucidal materials (nano-antivirals) have shown activity in the solid state. Therefore, they are very useful in the development of several products, such as fabric and high-touch surfaces. This review thoroughly and critically identifies recently developed nano-antivirals and their products, nano-antiviral deposition methods on various substrates, and possible mechanisms of action. By considering the commercial viability of nano-antivirals, recommendations are made to develop scalable and sustainable nano-antiviral products with contact-killing properties. Graphical Abstract","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44268584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Layered GeI2: A wide-bandgap semiconductor for thermoelectric applications–A perspective","authors":"Archit Dhingra","doi":"10.3389/fnano.2022.1095291","DOIUrl":"https://doi.org/10.3389/fnano.2022.1095291","url":null,"abstract":"Layered GeI2 is a two-dimensional wide-bandgap van der Waals semiconductor, which is theorized to be a promising material for thermoelectric applications. While the value of the experimentally extrapolated indirect optical bandgap of GeI2 is found to be consistent with the existing theoretical calculations, its potential as a thermoelectric material still lacks experimental validation. In this Perspective, recent experimental efforts aimed towards investigating its dynamical properties and tuning its bandgap further, via intercalation, are discussed. A thorough understanding of its dynamical properties elucidates the extent of electron-phonon scattering in this system, knowledge of which is crucial in order to open pathways for future studies aiming to realize GeI2-based thermoelectric devices.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48054616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji‐Yong Shin, Mahnmin Choi, Meeree Kim, Sohee Jeong
{"title":"Semiconductor clusters: Synthetic precursors for colloidal quantum dots","authors":"Ji‐Yong Shin, Mahnmin Choi, Meeree Kim, Sohee Jeong","doi":"10.3389/fnano.2022.1069178","DOIUrl":"https://doi.org/10.3389/fnano.2022.1069178","url":null,"abstract":"Semiconductor clusters have been implicated as reaction intermediates between molecular precursors and colloidal quantum dots (CQDs). The success of isolation of semiconductor clusters have enabled detailed investigation of the atomic information of semiconductor clusters. The identification of atomic information has emerged as an important topic because knowledge of the structure-function relationship of intermediate clusters has been helpful to reveal the synthetic mechanism of CQDs. Recently, they have been utilized as the synthetic precursors for CQDs, which was not readily achieved using conventional molecular precursors. This mini review briefly introduces the current understanding of their atomic information such as the composition, structure, and surface. We then discuss advantages, limitations, and the perspective of semiconductor clusters as a precursor for synthesis of CQDs.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43240023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reema Iqbal, Sadia Khan, H. M. Ali, Maham Khan, Shahid Wahab, Tariq Khan
{"title":"Application of nanomaterials against SARS-CoV-2: An emphasis on their usefulness against emerging variants of concern","authors":"Reema Iqbal, Sadia Khan, H. M. Ali, Maham Khan, Shahid Wahab, Tariq Khan","doi":"10.3389/fnano.2022.1060756","DOIUrl":"https://doi.org/10.3389/fnano.2022.1060756","url":null,"abstract":"Researchers are now looking to nanomaterials to fight serious infectious diseases that cause outbreaks and even pandemics. SARS-CoV-2 brought chaos to almost every walk of life in the past 2 years and has challenged every available treatment method. Although vaccines were developed in no time against it, the most pressing issue was the emergence of variants of concern arising because of the rapidly evolving viral strains. The higher pathogenicity and, in turn, the higher mortality rate of infections caused by these variants renders the existing vaccines less effective and the effort to produce further vaccines a costly endeavor. While several techniques, such as immunotherapy and repurposed pharmaceutical research, are being studied to minimize viral infection, the fundamentals of nanotechnology must also be considered to enhance the anti-SARS-CoV-2 efforts. For instance, silver nanoparticles (AgNPs) have been applied against SARS-CoV-2 effectively. Similarly, nanomaterials have been tested in masks, gloves, and disinfectants to aid in controlling SARS-CoV-2. Nanotechnology has also contributed to diagnoses such as rapid and accurate detection and treatment such as the delivery of mRNA vaccines and other antiviral agents into the body. The development of polymeric nanoparticles has been dubbed a strategy of choice over traditional drugs because of their tunable release kinetics, specificity, and multimodal drug composition. Our article explores the potential of nanomaterials in managing the variants of concern. This will be achieved by highlighting the inherent ability of nanomaterials to act against the virus on fronts such as inhibition of SARS-CoV-2 entry, inhibition of RNA replication in SARS-CoV-2, and finally, inhibition of their release. In this review, a detailed discussion on the potential of nanomaterials in these areas will be tallied with their potential against the current and emerging future variants of concern.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47559792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}