D. B. Olawade, O. Z. Wada, Oluwaseun Fapohunda, Bamise I. Egbewole, Olawale Ajisafe, Abimbola O. Ige
{"title":"Nanoparticles for microbial control in water: mechanisms, applications, and ecological implications","authors":"D. B. Olawade, O. Z. Wada, Oluwaseun Fapohunda, Bamise I. Egbewole, Olawale Ajisafe, Abimbola O. Ige","doi":"10.3389/fnano.2024.1427843","DOIUrl":"https://doi.org/10.3389/fnano.2024.1427843","url":null,"abstract":"Waterborne microbial contamination poses significant threats to public health and environmental sustainability. Traditional water treatment methods, while effective to a certain extent, are often limited in their ability to completely eradicate microbial pathogens and mitigate emerging challenges such as disinfection by-products and microbial resistance. In recent years, nanoparticles have emerged as promising candidates for microbial control in water treatment due to their unique physicochemical properties and antimicrobial efficacy. This review provides a comprehensive examination of the use of nanoparticles for microbial control in water treatment, focusing on their antimicrobial mechanisms, applications, and ecological implications. The review discusses the types of nanoparticles commonly used in water treatment, including silver nanoparticles, copper nanoparticles, titanium dioxide nanoparticles, and carbon-based nanoparticles, and examines their antimicrobial mechanisms, such as cell membrane damage, reactive oxygen species generation, and interference with microbial metabolic processes. Furthermore, the review explores the applications of nanoparticles in the disinfection of drinking water, wastewater treatment, water purification in remote areas, and biofilm control. Additionally, the ecological implications of nanoparticle-based water treatment, including nanoparticle release into the environment, environmental persistence, toxicity to non-target organisms, and regulatory challenges, are critically evaluated. Finally, future perspectives and challenges in nanoparticle-based water treatment, such as enhanced nanoparticle synthesis and stability, development of sustainable treatment technologies, integration with conventional methods, and addressing knowledge gaps, are discussed. Overall, this review provides valuable insights into the potential of nanoparticles as innovative tools for addressing microbial contamination in water treatment while highlighting the need for further research and sustainable practices to ensure their safe and effective implementation.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141804973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. J. Santos-Santos, J. A. Zamora-Justo, G. R. Vázquez-Martínez, R. Cabrera-Sierra, J. A. Balderas-López
{"title":"Synthesis of gold nanoparticles coated with glucose oxidase using PVP as passive adsorption linkage","authors":"I. J. Santos-Santos, J. A. Zamora-Justo, G. R. Vázquez-Martínez, R. Cabrera-Sierra, J. A. Balderas-López","doi":"10.3389/fnano.2024.1419239","DOIUrl":"https://doi.org/10.3389/fnano.2024.1419239","url":null,"abstract":"Gold nanoparticles (AuNPs) have great potential as biosensors for glucose detection due to their high sensitivity, as well as their extraordinary physical and chemical properties that improve compatibility with different biorecognition molecules, such as glucose oxidase (GOx). In this work the D-glucose quantification was determined by using the traditional technique based on biochemical reaction of GOx and AuNPs functionalized with polyvinylpirrolidone (PVP) polymer and the enzyme. The AuNPs-PVP-GOx nanocomplexes were characterized by ultraviolet-visible (UV-Visible), Infrared (FTIR), and Raman spectroscopies, as well as scanning electron microscopy (SEM), Z potential, dynamic light scattering (DLS), and thermogravimetry analysis (TGA). In general, these techniques showed significant differences after each functionalization stage with PVP and GOx, for instance it was observed: the presence of different functional groups, an increase of hydrodynamic diameter from 48.60 to 198.77 nm, a shift of the band absorption to larger wavelength, a change in the surface potential and weight loss, and in the morphology of the nanocomplex, which confirm the functionalization. In addition, the enzymatic activity of the AuNPs-PVP-GOx was confirmed through the detection of triiodide ions by UV-Visible spectrophotometry, coming from the oxidation reaction of iodide ions in the presence of H2O2. Furthermore, the nanocomplex synthesized by passive adsorption was evaluated as a possible biosensor for the quantification of D-glucose using a colorimetric assay, obtaining greater sensitivity than the traditional method. These findings indicate that PVP can be used as a linkage medium between AuNPs and GOx, which in turn can be used as a biosensor for the detection of D-glucose at low concentrations in biological fluids.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141828487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspects of 6th generation sensing technology: from sensing to sense","authors":"Hirak Mazumdar, Kamil Reza Khondakar, Suparna Das, Ajeet Kaushik","doi":"10.3389/fnano.2024.1434014","DOIUrl":"https://doi.org/10.3389/fnano.2024.1434014","url":null,"abstract":"The 6th-generation (6G) sensing technology is transforming the ways we perceive and interact with the world in real scenarios. It combines advanced materials, sophisticated algorithms, and connectivity to create intelligent, context-aware systems that can interpret and respond to environmental stimuli with unprecedented accuracy and speed. The key advancements include 1) ultra-sensitive sensors capable of detecting physical, chemical, and biological changes at low concentrations, 2) the integration of artificial intelligence (AI) and machine learning (ML) for enhanced data processing, and 3) the deployment of IoT networks with 5th-generation (5G) for seamless data transmission and real-time analysis. These cutting-edge technologies create immersive environments where devices capture data and anticipate user needs and environmental conditions. The 6G sensing technology has potential applications across sectors like point-of-care (PoC), healthcare, urban planning, and environmental monitoring. The transition from sensing to sense-making represents a paradigm shift, fostering a more intuitive, responsive, and interconnected world. The article provides a comprehensive overview of the current state and prospects of 6G sensing technology, highlighting its transformative potential and the challenges in realizing its full capabilities.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Women in nanotechnology: Vol. I","authors":"Neha Kaushik","doi":"10.3389/fnano.2024.1443473","DOIUrl":"https://doi.org/10.3389/fnano.2024.1443473","url":null,"abstract":"","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filippos Sofos, Konstantinos Ritos, A. Avramopoulos
{"title":"Editorial: Nanofluidics: computational methods and applications","authors":"Filippos Sofos, Konstantinos Ritos, A. Avramopoulos","doi":"10.3389/fnano.2024.1431198","DOIUrl":"https://doi.org/10.3389/fnano.2024.1431198","url":null,"abstract":"","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141344992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunomodulatory effects of laser-synthesized nanodiamonds on peripheral blood mononuclear cells: evaluation of unconjugated, PEGylated, and antibody-conjugated formulations","authors":"Elena Alexander, Kam W. Leong","doi":"10.3389/fnano.2024.1352287","DOIUrl":"https://doi.org/10.3389/fnano.2024.1352287","url":null,"abstract":"The application of laser-synthesized nanodiamonds (LNDs) is of great interest to biomedical researchers and drug developers because this emerging method of synthesis yields nanodiamonds of consistent size (<5 nm diameter) and surface chemistry that can be functionalized to perform a staggering range of highly specialized tasks. The present study assessed the threshold at which LNDs in various conjugations and concentrations triggered immune responses and cytotoxicity in peripheral mononuclear blood cells from healthy donors, as assessed by changes in ATP concentrations and induced secretion of the cytokines IFN-γ, IL-6 and TNF-α. Conjugations assessed were raw (unconjugated) NDs, PEGylated (PEG5k-NDs), and antibody conjugated to goat anti-mouse antibodies (IgG-NDs). Concentrations of each conjugation were prepared and tested at 50.0, 10.0, 2.0, 0.4, and 0.08 μg/mL. Results showed that pegylated and raw NDs were well tolerated, with the indicators of inflammation or minimal cytotoxicity emerging only at the highest concentrations tested (50.0 μg/mL). IgG-NDs showed signs of inflammatory responses at the two highest concentrations tested (10.0 and 50.0 μg/mL). There was some evidence that the dilutant vehicle used for ND suspension may have contributed to the immune response. All three ND configurations increased ATP concentration in a dose-dependent manner, up to a concentration of 10.0 μg/mL. At the highest concentration (50.0 μg/mL), the ND solutions showed minimal signs of cytotoxicity. Conclusion from this testing suggest that LNDs are likely to offer substantial utility in biomedical applications because of their capacity to evade the immune response at concentrations at least as high as 2.0 μg/mL and potentially up to 50.0 μg/mL.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141122405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Cunha de Castro, E. Resende, Igor Taveira, A. Enrich-Prast, F. Abreu
{"title":"Nanotechnology boosts the production of clean energy via nanoparticle addition in anaerobic digestion","authors":"J. Cunha de Castro, E. Resende, Igor Taveira, A. Enrich-Prast, F. Abreu","doi":"10.3389/fnano.2024.1406344","DOIUrl":"https://doi.org/10.3389/fnano.2024.1406344","url":null,"abstract":"Biogas production via anaerobic digestion is an established and robust technology that produces energy and recycles nutrients. Several biotechnological attempts have been applied to this process to increase biogas production, including adding nanoparticles, but several discrepancies have been reported. To elucidate the contradictory results, we performed a literature review followed by a meta-analysis to evaluate the effect of adding natural nanoparticles to biogas sludge. Our results showed that adding nanoparticles can increase biogas production by up to two orders of magnitude. Considering that, we attribute these results to variability in the nanoparticles applied, leading to less reliable, consistent, and even contradictory results. We observed that the magnetite nanoparticles are the most tested ones with the most promising positive effects. In addition, we observed that concentrations of nanoparticles higher than 100 mg/L can have adverse effects, with an overall decrease in biogas production. The findings in this study highlight the need for a proper characterization of the nanomaterials type and concentration applied to the process to understand the interactions and effects on the microbial communities and dynamics that lead to an overall increase or decrease in biogas yield.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Harnessing ferroic ordering in thin film devices for analog memory and neuromorphic computing applications down to deep cryogenic temperatures","authors":"Sayani Majumdar","doi":"10.3389/fnano.2024.1371386","DOIUrl":"https://doi.org/10.3389/fnano.2024.1371386","url":null,"abstract":"The future computing beyond von Neumann era relies heavily on emerging devices that can extensively harness material and device physics to bring novel functionalities and can perform power-efficient and real time computing for artificial intelligence (AI) tasks. Additionally, brain-like computing demands large scale integration of synapses and neurons in practical circuits that requires the nanotechnology to support this hardware development, and all these should come at an affordable process complexity and cost to bring the solutions close to market rather soon. For bringing AI closer to quantum computing and space technologies, additional requirements are operation at cryogenic temperatures and radiation hardening. Considering all these requirements, nanoelectronic devices utilizing ferroic ordering has emerged as one promising alternative. The current review discusses the basic architectures of spintronic and ferroelectric devices for their integration in neuromorphic and analog memory applications, ferromagnetic and ferroelectric domain structures and control of their dynamics for reliable multibit memory operation, synaptic and neuronal leaky-integrate-and-fire (LIF) functions, concluding with their large-scale integration possibilities, challenges and future research directions.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140977128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Schmitt, A. Ascoli, I. Messaris, A. S. Demirkol, S. Menzel, V. Rana, R. Tetzlaff, L. O. Chua
{"title":"Theoretico-experimental analysis of bistability in the oscillatory response of a TaOx ReRAM to pulse train stimuli","authors":"N. Schmitt, A. Ascoli, I. Messaris, A. S. Demirkol, S. Menzel, V. Rana, R. Tetzlaff, L. O. Chua","doi":"10.3389/fnano.2024.1301320","DOIUrl":"https://doi.org/10.3389/fnano.2024.1301320","url":null,"abstract":"Fading memory is the capability of a physical system to approach a unique asymptotic behaviour, irrespective of the initial conditions, when stimulated by an input from a certain class. Standard stimuli from the AC periodic class typically induce fading memory effects in non-volatile memristors, as uncovered for the first time back in 2016. Very recently, a deep investigation of resistance switching phenomena in a TaOx resistive random access memory cell revealed the capability of the nano-device to exhibit one of two possible oscillatory behaviours, depending upon the initial condition, when subject to a particular periodic excitation. This interesting finding was, however, left unexplained. Bistability is the simplest form of local fading memory. In a system, endowed with local fading memory under a given stimulus, the initial condition does not affect the long-term behaviour of the state as long as it is drawn from the basin of attraction of either of the distinct coexisting state-space attractors (two limit cycles for the periodically forced memristor acting as a bistable oscillator). Here, the history of the system, encoded in the initial condition, is, thus, erasable only locally through ad hoc stimulation. Motivated by the discovery of local history erase effects in our resistive random access memory cell, this study applies a powerful system-theoretic tool, enabling the analysis of the response of first-order systems to square pulse train-based periodic stimuli, known as the time-average state dynamic route, to an accurate physics-based mathematical model, earlier fitted to the nano-device, to determine a strategy for specifying the parameters of an excitation signal, consisting of the sequence of two square pulses of opposite polarity per period so as to induce various forms of monostability or multistability in the non-volatile memristor. In particular, as an absolute novelty in the literature, experimental measurements validate the theoretical prediction on the capability of the device to operate as one of two distinct oscillators, depending upon the initial condition, under a specific pulse train excitation signal. The coexistence of multiple oscillatory operating modes in the periodically forced resistive random access memory cell, an example par excellence of their unique non-linear dynamics, may inspire the development and circuit implementation of novel sensing and mem-computing paradigms.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140974051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visible-light-driven BiOI and GO/BiOI photocatalysts for organic pollutants degradation and hydrogen production using low power sources","authors":"Socorro Oros-Ruiz, Hiram Joazet Ojeda-Galván, Mildred Quintana, Roberto Leyva-Ramos, Adriana Isabel Moral-Rodríguez, Esmeralda Mendoza-Mendoza","doi":"10.3389/fnano.2024.1388458","DOIUrl":"https://doi.org/10.3389/fnano.2024.1388458","url":null,"abstract":"BiOI and (3 wt%)GO/BiOI visible-light-driven photocatalysts were obtained by a one-pot solvothermal method and successfully applied to the degradation of single and binary dye solutions of rhodamine B (RhB) and methylene blue (MB) and H2 production using very low-power sources. The GO/BiOI with hierarchical flower morphologies exhibited the highest activity, achieving RhB and MB photodegradation percentages (%Xdye) of 100% and 80%, respectively, in 240 min employing a simple 19 W white LED array. Furthermore, GO/BiOI dosage and RhB initial concentration play an essential role in dye degradation, and scavenger assays confirmed that holes and superoxides are the main species causing RhB oxidation. TOC analysis determined an efficiency of 70%, and after three uses, the GO/BiOI attained a %XRhB of 84%. The H2 evolution was performed under 2 W UV light, yielding 323.25 μmol/h∙g of H2 for BiOI, and the addition of GO nanosheets increased the photoactivity of GO/BiOI up to 63% (509.61 μmol/h∙g). The catalytic activity of GO/BiOI is superior to values reported in the literature considering nominal power consumption (kWh) vs. efficiency of RhB degradation or H2 production.","PeriodicalId":34432,"journal":{"name":"Frontiers in Nanotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140977132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}