Santa Cruz Roberto , Domeniconi Gustavo , Favot Carolina , Pagano Fernando , Choi Marcelo
{"title":"Prognostic Value of Consolidation in Lung Tomography in Patients With Acute Respiratory Distress Syndrome","authors":"Santa Cruz Roberto , Domeniconi Gustavo , Favot Carolina , Pagano Fernando , Choi Marcelo","doi":"10.1016/j.opresp.2024.100366","DOIUrl":"10.1016/j.opresp.2024.100366","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100366"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142440880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Ferrer-Pargada , David Iturbe , Sandra Tello , Sheila Izquierdo , Elena Peña , Cristina Castrillo Bustamante , Javier Gómez-Roman
{"title":"Flecainide-associated Pneumonitis, a Case Report: COVID is Not All That it Seems","authors":"Diego Ferrer-Pargada , David Iturbe , Sandra Tello , Sheila Izquierdo , Elena Peña , Cristina Castrillo Bustamante , Javier Gómez-Roman","doi":"10.1016/j.opresp.2024.100372","DOIUrl":"10.1016/j.opresp.2024.100372","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100372"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Lojo-Lendoiro , Ignacio Díaz-Lorenzo , Jose Andrés Guirola Ortíz , Fernando Gómez Muñoz
{"title":"Pulmonary Embolism: Is AI One of the Team?","authors":"Sara Lojo-Lendoiro , Ignacio Díaz-Lorenzo , Jose Andrés Guirola Ortíz , Fernando Gómez Muñoz","doi":"10.1016/j.opresp.2024.100371","DOIUrl":"10.1016/j.opresp.2024.100371","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100371"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Personalized Medicine in Severe Asthma: Bridging the Gaps","authors":"Juan Luis García-Rivero , Ismael García-Moguel","doi":"10.1016/j.opresp.2024.100368","DOIUrl":"10.1016/j.opresp.2024.100368","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100368"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142440877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COPD Exacerbation by SARS-CoV-2. A Cause of Future Poor Disease Control?","authors":"Juan Marco Figueira-Gonçalves , Rafael Golpe","doi":"10.1016/j.opresp.2024.100369","DOIUrl":"10.1016/j.opresp.2024.100369","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100369"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142440878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Feltrer-Martínez , Sandra Orozco , Ana Alonso , Paloma Millan-Billi , Silvia Barril , Gisela Ruibal , Joel Francesqui , David Lobo-Prat , Ana Gimenez , Laura Lopez , Laura Martinez-Martinez , Ivan Castellvi , Diego Castillo
{"title":"Older Patients With Interstitial Lung Disease Feature a Distinct Clinical Profile","authors":"Laura Feltrer-Martínez , Sandra Orozco , Ana Alonso , Paloma Millan-Billi , Silvia Barril , Gisela Ruibal , Joel Francesqui , David Lobo-Prat , Ana Gimenez , Laura Lopez , Laura Martinez-Martinez , Ivan Castellvi , Diego Castillo","doi":"10.1016/j.opresp.2024.100374","DOIUrl":"10.1016/j.opresp.2024.100374","url":null,"abstract":"<div><h3>Introduction</h3><div>There are few studies investigating the clinical profile of older patients with interstitial lung disease (ILD), so this study investigated the characteristics of the older population diagnosed with ILD.</div></div><div><h3>Material and methods</h3><div>Retrospective study in a population of new referrals at an ILD clinic from January 2013 to September 2017. Patients over 64 years were selected. Data collection included diseases variables, diagnostic procedures and comorbidities. Gender-age-physiology (GAP) stage, composite physiologic index (CPI) and Charlson index was calculated. Statistical analysis was performed to investigate risk factors associated with survival.</div></div><div><h3>Results</h3><div>A total of 232 patients were included in this study. Mean age was 76.3 years (SD 6.5). As per protocol, 69.3% completed the initial assessment but this was lower in the elderly group (61.5%). The most frequent diagnosis was unclassifiable ILD (24.1%), followed by ILD associated with connective tissue disease (21.6%), IPF (12.1%) and hypersensitivity pneumonitis (10.3%). During follow-up (36.7 months (SD 28.6)) a significant proportion of patients died (55 cases, 23.7% of the cohort), especially in the late older group (30.4%). Kaplan–Meier curves showed that those over 75 years have a worse survival even when adjusted by covariables (<em>p</em> <!--><<!--> <!-->0.001). CPI was the only score with statistical significance in a multivariate analysis (HR 1.06. <em>p</em> 0.006).</div></div><div><h3>Conclusions</h3><div>Older adults with ILD featured a distinct clinical profile. Our findings highlight the need to develop non-invasive biomarkers and specific scores adapted to this age-group.</div></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 4","pages":"Article 100374"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Vigil, Toni Zapata, Andrea Grau, Marta Bonet, Montserrat Montaña, María Piñar
{"title":"Innovación en sueño","authors":"Laura Vigil, Toni Zapata, Andrea Grau, Marta Bonet, Montserrat Montaña, María Piñar","doi":"10.1016/j.opresp.2025.100402","DOIUrl":"10.1016/j.opresp.2025.100402","url":null,"abstract":"<div><div>Advances in sleep medicine have driven significant improvements in the diagnosis and treatment of sleep disorders such as obstructive sleep apnea (OSA). This disorder affects one billion people worldwide and traditionally, diagnosis is based on polysomnography (PSG), a laborious method that requires specialized personnel. However, the integration of artificial intelligence (AI) in sleep medicine has made it possible to automate the analysis of sleep phases and respiratory events with high accuracy.</div><div>Machine learning algorithms and neural networks have proven to be effective in automatic sleep coding, with hit rates comparable to those of human experts. These advances make it possible to improve the efficiency of sleep labs and to personalize OSA treatment. In addition, techniques such as cluster analysis are used to identify symptomatic patterns and phenotypes, which improves understanding of OSA pathophysiology and optimizes CPAP treatment.</div><div>However, implementation of AI in hospitals faces technological, ethical, and legal barriers. Challenges include data quality, patient privacy, and the need for specialized personnel. Despite these obstacles, AI and Big Data have the potential to transform medical care for sleep disorders, improving both diagnosis and treatment adherence, provided regulatory and cultural barriers are overcome.</div></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100402"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Fernández-Tena , Carlos Arnedo , Guillaume Houzeaux , Beatriz Eguzkitza
{"title":"Gemelos digitales pulmonares","authors":"Ana Fernández-Tena , Carlos Arnedo , Guillaume Houzeaux , Beatriz Eguzkitza","doi":"10.1016/j.opresp.2024.100394","DOIUrl":"10.1016/j.opresp.2024.100394","url":null,"abstract":"<div><div>The development of lung digital twins (DTs) represents a significant advance in personalized medicine, providing a virtual framework that replicates the structure, function, and pathology of the respiratory system in an individualized manner. DTs integrate clinical data, high-resolution images, and mathematical models to simulate respiratory mechanics, gas diffusion, and fluid dynamics in real time. This technology improves diagnosis, treatment planning, and disease progression monitoring. One of the key applications of lung DTs is the ability to simulate patient-specific response to treatments and predict outcomes, allowing for personalized therapies. Despite advances, the implementation of DTs in clinical practice faces challenges related to data integration, computational efficiency, and ethical considerations regarding data privacy. Nevertheless, lung DTs offer clear promise for improving precision medicine, optimizing patient care, and improving clinical outcomes.</div></div>","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100394"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andres Obeso , Numan Balci , Yusuf Bayrak , Usman Ahmad
{"title":"Innovative Use of 3D Reconstruction Models of the Pulmonary Artery for Preoperative Planning","authors":"Andres Obeso , Numan Balci , Yusuf Bayrak , Usman Ahmad","doi":"10.1016/j.opresp.2024.100380","DOIUrl":"10.1016/j.opresp.2024.100380","url":null,"abstract":"","PeriodicalId":34317,"journal":{"name":"Open Respiratory Archives","volume":"6 ","pages":"Article 100380"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}