Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)最新文献
{"title":"The effects of misalignment of the center of rotation of the ankle on stiffness measurements","authors":"B. Schmidt, J. Given, J. Dewald","doi":"10.1109/IEMBS.1997.757090","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.757090","url":null,"abstract":"Misalignment of the center of rotation of the ankle with the axis of rotation of an actuator results in significant error in measured ankle torque during passive ranging of the ankle. As a result, estimates of ankle stiffness must account for this misalignment torque. We quantified misalignment torques and foot plate forces in the human ankle with measured displacements in two orthogonal directions. The resulting foot plate forces were consistent with the forces predicted by the mechanics of the system. These data will be used to align the center of rotation of the ankle with the actuator axis of rotation. This alignment procedure will improve the validity of experimental comparisons when monitoring longitudinal changes in the mechanical properties of the ankle following spinal cord injury.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"97 5-6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114025404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New insights into ventricular tachyarrhythmia onset using heart rate signals decomposition","authors":"G. Thonet, E. Pruvot, J. Vesin, M. Fromer","doi":"10.1109/IEMBS.1997.756976","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756976","url":null,"abstract":"Presents new insights into ventricular tachyarrhythmia (VTA) onset based on a large population of patients implanted with cardiovertor-defibrillators. The analysis method consists in the decomposition of heart rate signals according to the main physiological frequency bands. The evolution of temporal and spectral indices is assessed separately for each band at two-minute intervals. On the overall population, the results suggest a sustained sympathetic activity prior to VTA onset, a progressive increase in sympathetic tone and a decrease in parasympathetic modulation of the heart at the onset of VTA. Moreover, distinctions are made for three cardiopathies: coronary artery disease, dilatative cardiomyopathy and primary electrical disease. Subsequent results pave the way for promising advances in the understanding of arrhythmic events.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114826732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic effect of Vitamin C on electroporation mediated muscle injury in vivo","authors":"G. Abramov, M. Bier, J. Hannig, R.C. Lee","doi":"10.1109/IEMBS.1997.756827","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756827","url":null,"abstract":"High voltage electrical shock can produce extensive muscle and nerve tissue damage due to thermal denaturation of proteins and poration of cell membranes by electric field gradients. To study the therapeutic effect of Vitamin C on the neurophysiologic performance of motor nerves following electrical injury, the authors used an in vivo model exposing an anesthetized rat's hindlimb to thermally neutral electrical shocks. The applied pulsed electrical fields had a strength of approximately 150 V/cm. A standard EMG test was used to monitor the damage and recovery of the motor nerve function. Intravenously administered Vitamin C at concentrations of 5.8 mg/kg and 340 mg/kg showed a dose-dependent, statistically significant improvement in the recovery of the muscle action potential amplitude.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"05 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124480497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ellmerer, P. Wach, Trajanoski, L. Schaupp, W. Regittnig, G. Brunner, G. Sendlhofer, A. Wutte, F. Skrabal, T. Pieber
{"title":"Open flow microperfusion-interstitial sampling of large molecules","authors":"M. Ellmerer, P. Wach, Trajanoski, L. Schaupp, W. Regittnig, G. Brunner, G. Sendlhofer, A. Wutte, F. Skrabal, T. Pieber","doi":"10.1109/IEMBS.1997.756797","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756797","url":null,"abstract":"In this study the open flow microperfusion technique was used to sample interstitial fluid from the subcutaneous adipose tissue of 6 healthy volunteers during a 6-h fast. The system is based on a perforated double lumen catheter which is perfused by isotonic, ionfree perfusate. The collected samples were analysed for substances of different molecular weight (sodium, potassium, glucose, lactate and albumin). The results indicate that all considered substances could be sampled and measured during the whole study period. The sodium, potassium and lactate concentrations did not change (p<0.05 versus basal level) during the study. However, a significant decrease (p<0.05 vs. basal level) of the glucose and the albumin concentration were observed 3 hours and 1.5 hours after insertion of the catheter, respectively. In this study it could be shown that sampling of molecules even with a high molecular weight like albumin is possible. The gradual but slow decline of the glucose and albumin concentration in the sampled perfusate might be caused by drainage through the relatively high perfused catheter (4 /spl mu/l/spl middot/min/sup -1/).","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"65 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124533658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An estimation of the correlation dimension for the EEG in emotional states","authors":"C. S. Ryu, Seunghwan Kim, S. Park, M. Whang","doi":"10.1109/IEMBS.1997.757006","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.757006","url":null,"abstract":"To study the underlying dynamics of emotional states in the human brain by a nonlinear dynamical analysis, we estimate the correlation dimension for the electroencephalogram (EEG) in positive and negative emotional states. The time delay for the reconstruction of the EEG in the embedding space is not determined from a single function, such as the autocorrelation function, but is determined to yield the largest plateau in the local slope of the correlation integral for each embedding dimension. In our case, the absence of an abrupt change in magnitudes of singular values makes singular value decomposition useless, which implies the absence of a dominant process in emotional states. Our results show that the correlation exponent for the emotional state is higher than that for the rest state even if the variation between subjects is considered. This may be a first step to discriminate between \"Yes\" and \"No\" for communication via EEG, particularly for severely disabled people.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127790660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wavelet analysis of phonocardiograms: differences between normal and abnormal heart sounds","authors":"F. Jandre, M.N. Souza","doi":"10.1109/IEMBS.1997.757032","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.757032","url":null,"abstract":"Phonocardiography-based diagnosis can be improved by modern techniques of signal processing. This work investigates the analysis of phonocardiograms using the time-frequency distribution generated by the cochlear wavelet transform. We show here a comparative study of normal and abnormal heart sounds, whose scalograms exhibit noticeable morphological differences in terms of duration and spectral composition of sounds. These differences suggest that the cochlear-wavelet-based scalogram can become an interesting approach to design automatic diagnosis systems.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126242251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donald, Masini, W. Paulsen, Riehard, Brouillard, Vijay, Iyerl
{"title":"Fetal transmission pulse oximetry","authors":"Donald, Masini, W. Paulsen, Riehard, Brouillard, Vijay, Iyerl","doi":"10.1109/IEMBS.1997.758830","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.758830","url":null,"abstract":"This paper describes the characterization and validation of a fetal transmission pulse oximetry system using in vivo measurement and statistical analysis techniques. Methods and results from immature piglet studies using the fetal pulse oximetry sensor are discussed.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126280399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A large scale memory (LAMSTAR) neural network for medical diagnosis","authors":"D. Graupe, H. Kordylewski","doi":"10.1109/IEMBS.1997.756622","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756622","url":null,"abstract":"Discusses applications of the LAMSTAR network to a medical diagnostic case; specifically, to a urologic medical diagnosis. The LAMSTAR network is a self trained network based on SOM (Self-Organizing-Map) modules. It employs arrays of link-weight vectors to channel information vertically and horizontally through the network to facilitate fast memory retrieval. For diagnosis, the LAMSTAR network displays the diagnosis with suggestions to perform specific further tests. Also, the network interpolate/extrapolate those subwords (states of car systems), that were not present in the input word. As a medical diagnostic tool, the LAMSTAR network evaluates patients' conditions and long term forecasting after removal of kidney stones. The LAMSTAR network attempts to predict the treatment's results (failure/success) by analyzing the correlations among 100 patients (input words), each described by 17 subwords. The paper thus illustrates the scope of applications of the LAMSTAR network.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128112563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Continuous measurement of segmental and whole body bio-impedance","authors":"F. Zhu, D. Schneditz, E. Wang, N. Levin","doi":"10.1109/IEMBS.1997.758761","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.758761","url":null,"abstract":"Measurement of whole body bioimpedance provides a non-invasive and practical approach to estimate extracellular volume (ECV) in man. However, recent data indicate that ECV cannot be treated as a homogeneous compartment without obtaining paradoxical results. Therefore, bioimpedance measurements should include measurements of body segments such as the arm, the trunk, and the leg. A digital switch was developed and used to consecutively select different body segments for the continuous measurement of whole body and segmental bioimpedance at a minimum sampling period of 3 seconds. Bioimpedance data were modeled to determine the resistance of the ECV in the segments and in the whole body for a period of 30 minutes where subjects were in supine body position followed by a 30 minute standing phase. During supine body position modeled extracellular resistance increased in the leg, the arm, and in the whole body but slightly increased in the trunk. Changes in extracellular resistance reversed with subjects assuming a standing position. These measurements reflect the shifts in ECV between segments to be expected with changes in body position. Simultaneous measurement of bioimpedance in different body segments utilizing this approach might be useful to analyze the nature of fluid shifts in clinical applications such as hemodialysis and ultrafiltration.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122273259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of coronary plaque in intravascular ultrasound using histological correlation","authors":"K. J. Dixon, D. Vince, R. Cothren, J. F. Cornhill","doi":"10.1109/IEMBS.1997.757663","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.757663","url":null,"abstract":"Atherosclerosis is a degenerative arterial disease that leads to the gradual blockage of vessels due to plaque formation or acute ischaemic events such as plaque rupture. A thorough understanding of plaque morphology is necessary in the determination of factors underlying coronary artery disease. Intravascular ultrasound (IVUS) represents a diagnostic technique that provides tomographic visualization of coronary arteries. Ultrasound reflects sound at the interfaces between tissue of different acoustic refractive indices theoretically implying that various components within an ultrasound image should be distinguishable. The aim of this study is to classify plaque lesions using advanced digital image processing. Diseased samples were obtained from excised human coronary arteries at autopsy. Intravascular ultrasound images were acquired using an HP Sonos clinical IVUS imaging system and 3.5 F, 30 MHz catheters. Regions of interest were selected within the IVUS images with plaque types determined from the corresponding histological sections. Second order statistical texture features were computed for each region of interest after which tissue classification was performed using discriminant analysis. Preliminary results show that classification and recognition of plaque type is possible for IVUS imaging in vitro. Various plaque types respond differently to clinical interventions and proper classification will therefore be invaluable in tracking the progression, regression, and treatment of coronary artery disease.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132338897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}