Brain Hemorrhages最新文献

{"title":"Mixed-reality head-mounted display in cranial neurosurgery: A proof-of-concept study","authors":"Lukas Andereggen, G. Boillat, J. Haegler, Philipp Gruber, Basil Erwin Grüter, S. Wanderer, Angelo Tortora, Gerrit A. Schubert, Hans-Jakob Steiger, Serge Marbacher","doi":"10.1016/j.hest.2024.07.003","DOIUrl":"https://doi.org/10.1016/j.hest.2024.07.003","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic yield of different imaging modalities in the detection rate of intracranial aneurysm remnants after microsurgical clipping – A systematic review and meta-analysis","authors":"Raphael Sidler, Lukas Andereggen, G.A. Schubert, B. Grüter, Serge Marbacher","doi":"10.1016/j.hest.2024.07.002","DOIUrl":"https://doi.org/10.1016/j.hest.2024.07.002","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation in intracerebral hemorrhage: A bibliometric perspective","authors":"Rui Zhang ,&nbsp;Ruoqi Ding ,&nbsp;Qiao Wang ,&nbsp;Linke Zhang ,&nbsp;Xiaochong Fan ,&nbsp;Fuyou Guo ,&nbsp;Xuemei Chen ,&nbsp;Chao Jiang ,&nbsp;Jing Cao ,&nbsp;Junmin Wang ,&nbsp;Weidong Zang ,&nbsp;Jian Wang","doi":"10.1016/j.hest.2024.01.003","DOIUrl":"10.1016/j.hest.2024.01.003","url":null,"abstract":"<div><h3>Objective</h3><p>Intracerebral hemorrhage (ICH) is a severe stroke that can adversely affect patient outcomes due to the accompanying inflammatory response. As a result, there is a growing interest in studying inflammation in ICH. We systematically reviewed relevant articles using the Web of Science to understand the literature on this subject. This study aims to provide a comprehensive overview of the field through bibliometric analysis, highlight its current status, identify frontiers, and speculate on future directions.</p></div><div><h3>Methods</h3><p>We conducted a bibliometric analysis of the global English literature on inflammation related to ICH research based on the Web of Science from 1993 to the present to address publication trends and research hotspots.</p></div><div><h3>Results</h3><p>A total of 885 publications were included from 1993 to 2023. These articles were authored by 7375 researchers from 1639 organizations in 68 countries and published in 571 journals. Collectively, they cited 48,980 references from 5621 journals. The author who published the most articles was Dr. Zhang, John H. Interestingly, 6 of the top ten most published authors were from China. Regarding the countries that published the most articles, China was at the top of the list, followed by the United States. The most frequently used keywords were “Inflammation”, “Neuroinflammation”, and “Microglia”. Regarding journal publication and reference citations, <em>Stroke</em> was the most published and cited journal.</p></div><div><h3>Conclusions</h3><p>Over the past 30 years, there has been considerable progress in scientific research concerning inflammation in the context of ICH. The pivotal themes of these studies have been immune cells and inflammatory mediators. It is worth noting, however, that most of the published literature on inflammation in ICH pertains to preclinical studies, with comparatively fewer clinical investigations. Several challenges must be addressed to translate these promising research achievements into clinical practice.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X24000032/pdfft?md5=e606002c1b01e2943d2bc866dd64d591&pid=1-s2.0-S2589238X24000032-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139537216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of crosstalk between cerebral immune cells and peripheral immune cells in the damage and protection of blood–brain barrier after intracerebral hemorrhage","authors":"Yihui Wang ,&nbsp;Wencao Liu ,&nbsp;Jianing Zhang ,&nbsp;Panpan Geng ,&nbsp;Xinchun Jin","doi":"10.1016/j.hest.2024.02.002","DOIUrl":"10.1016/j.hest.2024.02.002","url":null,"abstract":"<div><p>Blood-brain barrier (BBB) damage is a major pathological change after intracerebral hemorrhage (ICH) and is both the cause and result of brain edema and the inflammatory response post-ICH. Cerebral immune cells (CICs), including microglia, pericytes, and astrocytes play a crucial role in the damage and protection of the BBB after ICH. Recent evidence suggests that peripheral immune cells (PICs) also play an important role in BBB damage and protection, brain edema, and neurological function impairment. Therefore, regulating interactions between glial cells and immune cells is expected to alleviate ICH-induced BBB damage. In this review, we first introduce the role of CICs, endothelial cells (ECs), oligodendrocytes (OLs), and PICs in BBB damage and protection after ICH, focusing on their polarization and inflammatory response. Next, we specifically discuss the crosstalk between CICs and PICs, such as the brain-spleen axis and brain-gut axis after ICH. Finally, we suggest that glial cells, PICs and, meningeal lymphatic system may be potential targets for alleviating BBB damage after ICH, and discuss some molecular targets and potential strategies for alleviating BBB damage after ICH by modulating CICs, ECs, and PICs.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X24000159/pdfft?md5=f4f82d9fad453b6947d2ad9a479d5cd2&pid=1-s2.0-S2589238X24000159-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and factors in delayed neurological deficits after subarachnoid hemorrhage in mice","authors":"William Wroe ,&nbsp;Ari Dienel ,&nbsp;Sungha Hong ,&nbsp;Kanako Matsumura ,&nbsp;Jose Guzman ,&nbsp;Kiara Torres ,&nbsp;Angelica Bernal ,&nbsp;Hussein A. Zeineddine ,&nbsp;Peeyush Thankamani Pandit ,&nbsp;Spiros L. Blackburn ,&nbsp;Devin W. McBride","doi":"10.1016/j.hest.2023.12.006","DOIUrl":"10.1016/j.hest.2023.12.006","url":null,"abstract":"<div><h3>Objective</h3><p>Delayed cerebral ischemia (DCI) is one of the most feared complications in aneurysmal subarachnoid hemorrhage (SAH). Animal models are crucial to studying the disease mechanisms and potential treatments. DCI in rodents was thought to not exist; herein we examine literature and our experience with DCI in rodents.</p></div><div><h3>Methods</h3><p>Daily behavioral performance was assessed every day from day 1 to up to 7 days post-SAH on mice from 5 different studies that used the endovascular perforation model. Performance was graded using an 8-test sensorimotor neuroscore previously described. The daily neuroscore was then used to identify the incidence and timing of delayed neurological deficits (DND), a clinical surrogate for DCI. A total number of 298 mice (134 males, 164 females) were subjected to SAH. Fifty-one mice had histological staining done to identify infarct volume.</p></div><div><h3>Results</h3><p>The overall incidence of DND was 33.9%; 27.6% in males and 39.0% in females, but this difference was not statistically significant. The overall incidence of delayed death was 21.1%, and there was no significant difference for delayed mortality in females versus male mice. There is a non-statistically significant trend towards increased infarct volume in mice suffering DND.</p></div><div><h3>Conclusions</h3><p>Mice with endovascular puncture induced SAH develop DND at rates comparable to human patients. Future work needs to correlate the DND seen with decreased regional cerebral blood flow, another hallmark of DCI, but in spite of this need, researchers may use the murine models to test therapies for DCI after SAH.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000669/pdfft?md5=3a6d47bede9831f45699e6d118dfe55e&pid=1-s2.0-S2589238X23000669-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139192017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inspiration for the treatment of intracerebral hemorrhage from the duality of glial scar: The right time point for reactive astrocytes reprogramming","authors":"Liyang Huang ,&nbsp;Jingyi Wang ,&nbsp;Shiling Chen ,&nbsp;Xiaoxiao Xv ,&nbsp;Yuanwei Li ,&nbsp;Gaigai Li ,&nbsp;Zhouping Tang","doi":"10.1016/j.hest.2024.04.004","DOIUrl":"10.1016/j.hest.2024.04.004","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X24000317/pdfft?md5=8d62b5c51ac6f95358d513a60abbd75e&pid=1-s2.0-S2589238X24000317-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140762829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral venous impairment and cerebral venous sinus thrombosis","authors":"Jiaqi Wang ,&nbsp;Anatol Manaenko ,&nbsp;Qin Hu ,&nbsp;Xiaohua Zhang","doi":"10.1016/j.hest.2024.03.002","DOIUrl":"10.1016/j.hest.2024.03.002","url":null,"abstract":"<div><p>Cerebral veins are responsible for the outflow drainage of brain interstitial fluid (ISF). The importance of cerebral venous drainage has been emphasized in various neurological diseases. Impaired venous outflow may lead to brain edema, blood–brain barrier (BBB) disruption, inflammatory responses and hemorrhagic complications. With the development of imaging technologies, several imaging-based signs for venous assessment are proposed. Therapies targeting cerebral venous drainage have shown beneficial outcomes in cerebral venous sinus thrombosis (CVST) in clinic, however more insight into the cellular and molecular level should be elucidated. Here we review the pathological changes following cerebral venous drainage impairment, summary the advances in image-based evaluation, address the potential molecular mechanisms, and discuss venous drainage-focused therapies. A better understanding of cerebral venous drainage and its underlying mechanism will promote the pharmacological development and clinical management of CVST.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X24000263/pdfft?md5=490cc945d39f55ce93058e8a775a117f&pid=1-s2.0-S2589238X24000263-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140272548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral pupil sparing oculomotor nerve paresis with an anterior communicating artery aneurysm: A case report with literature review","authors":"Shuja Ikram,&nbsp;Ahtesham Khizar,&nbsp;Muhammad Waqas Umer","doi":"10.1016/j.hest.2023.08.002","DOIUrl":"10.1016/j.hest.2023.08.002","url":null,"abstract":"<div><h3>Objective</h3><p>An anterior communicating artery (ACoA) aneurysm causing unilateral pupil sparing oculomotor nerve paresis is highly unusual. This is, to the best of our knowledge, the second case report of its sort. Compression, ischemia, or haemorrhage affecting the anterior visual pathway are common neuro-ophthalmic manifestations of ACoA aneurysm but when there is partial paresis it only affects the superior division of the third cranial nerve's fibres which is an extremely rare occurrence.</p></div><div><h3>Case presentation</h3><p>A 45-year-old man came in as an outpatient with complaints of severe headache and right eyelid drooping for the previous 6 days. He had GCS 15 (E4,V5,M6), and right eyelid partial ptosis with normal reactive pupils. The other cranial nerves and neurological examination came out normal. A non-contrast enhanced computed tomography (CT) scan of the brain revealed a hyperdense area around the ACoA region and SAH. During CT angiography, an ACoA aneurysm was found. The patient was clipped on the 24th post-bleeding day. On the three-week follow-up appointment, the ptosis had improved somewhat.</p></div><div><h3>Conclusions</h3><p>Although unilateral pupil sparing oculomotor nerve paresis has little localising utility, it does help to comprehend acute microvascular spasm, which may have therapeutic implications.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000268/pdfft?md5=eb614f8b2e18e4d9f3ca5f6a6fc67d87&pid=1-s2.0-S2589238X23000268-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74256630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare central neurocytoma in fourth ventricle: A case report with intratumoral hemorrhage and cerebellar mutism syndrome","authors":"H. Setenay Unal ,&nbsp;R. Nur Balcın ,&nbsp;Pinar Eser ,&nbsp;Mine Ozsen ,&nbsp;Ahmet Bekar","doi":"10.1016/j.hest.2023.11.008","DOIUrl":"10.1016/j.hest.2023.11.008","url":null,"abstract":"<div><h3>Objective</h3><p>Central neurocytoma (CN) is a rare benign tumor usually found in the lateral and third ventricles. This report highlights an exceptional case of CN in the fourth ventricle, leading to acute hydrocephalus due to bleeding. The patient later developed cerebellar mutism syndrome (CMS), a rare condition following posterior fossa surgery. We retrospectively analyzed data from a patient who experienced sudden loss of consciousness due to hemorrhagic fourth ventricular CN.</p></div><div><h3>Case presentation</h3><p>A 43-year-old male presented with sudden loss of consciousness. Initial computed tomography (CT) scan revealed a large left cerebellar hemorrhagic lesion causing hydrocephalus. An external ventricular drainage catheter was inserted to alleviate hydrocephalus, followed by emergent surgery to address the mass. A second surgery was needed due to rebleeding, achieving complete tumor removal. A ventriculoperitoneal shunt was inserted for permanent hydrocephalus management. Post-surgery, the patient presented with significant neurological symptoms, including muteness, ataxia, and hypotonia, which improved with medical treatment involving fluoxetine and bromocriptine. A one-year follow-up magnetic resonance imaging (MRI) confirmed successful tumor removal with no signs of recurrence.</p></div><div><h3>Conclusion</h3><p>This case emphasizes the unusual occurrence of CN in the fourth ventricle with bleeding and the possibility of CMS in adult patients after posterior fossa surgery.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000591/pdfft?md5=dbdc7f6a2316cb88970b81224b12f900&pid=1-s2.0-S2589238X23000591-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139299323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of mechanical thrombectomy for acute ischemic stroke in primary immune thrombocytopenia patient: Case report and literature review","authors":"Hideki Nakajima ,&nbsp;Takuro Tsuchiya ,&nbsp;Shigetoshi Shimizu ,&nbsp;Hidenori Suzuki","doi":"10.1016/j.hest.2023.10.002","DOIUrl":"10.1016/j.hest.2023.10.002","url":null,"abstract":"<div><h3>Objective</h3><p>Primary immune thrombocytopenia (ITP) paradoxically carries a high risk of developing thrombosis. However, the efficacy of mechanical thrombectomy (MT) for acute ischemic stroke (AIS) in ITP patients remains unclear due to its rarity.</p></div><div><h3>Case presentation</h3><p>A 47-year-old female treated for chronic ITP for 2 years was admitted to the hematology department with severe thrombocytopenia. The patient was started on glucocorticoid therapy, and her platelet count rose soon. On sixth day of hospitalization, she suddenly presented with loss of consciousness, conjugate eye deviation to the left, and left hemiplegia. Magnetic resonance imaging and angiography showed an acute ischemic lesion with the left M1 occlusion. Emergent MT was performed and resulted in successful recanalization. Postoperatively, she recovered consciousness and was able to follow instructions. However, on the third day after MT, the patient suffered hemorrhagic infarction and brain herniation, and decompression craniectomy was performed. Her consciousness slowly recovered, and cranioplasty was performed after brain swelling improved. The patient was transferred to a rehabilitation hospital with modified Rankin Scale (mRS) 4 on 84th day of hospitalization, and eventually improved to mRS 3 with motor aphasia and right hemiparesis.</p></div><div><h3>Conclusion</h3><p>MT may be effective for AIS in ITP patients with appropriate case selection.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000402/pdfft?md5=a58e45aec021030c47540a55da4683ae&pid=1-s2.0-S2589238X23000402-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135762535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}