Addiction and Health最新文献

{"title":"The Purpose of Research: Clarifying Aims, Goals, Objectives, and Targets.","authors":"Parsa Ghasemi, Khosrow Kashfi, Asghar Ghasemi","doi":"10.34172/ahj.1748","DOIUrl":"10.34172/ahj.1748","url":null,"abstract":"<p><strong>Introduction: </strong>Research is a purpose-directed activity. Although aims, goals, objectives, and targets are interrelated statements of purpose, they differ in hierarchy, scope, measurability, timeframe, and significance. This brief review clarifies these terms and describes the characteristics of a good research objective.</p><p><strong>Methods: </strong>Relevant papers were analyzed to delineate the definitions, interrelations, and distinctions among aims, goals, objectives, and targets in research projects.</p><p><strong>Results: </strong>The apparent purpose of a study (objectives and goals) addresses specific research questions, whereas its deeper purpose (aim) represents the underlying reason for conducting the study. Aims express ideals and long-term direction; goals outline the primary intent and problem to be addressed; objectives link intention to action by specifying how the research question will be answered; and targets indicate desired values of outcome indicators. A strong objective should be SMART (specific, measurable, achievable, relevant, and time-bound).</p><p><strong>Conclusion: </strong>Clear articulation of research purpose facilitates translation of findings into practice and enhances the overall quality of research.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1748"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Olfactory Hypersensitivity to Opium and Cannabis Following Naltrexone Administration: A Rare Case Report.","authors":"Seyed Hamzeh Hosseini, Raheleh Rafaiee","doi":"10.34172/ahj.1746","DOIUrl":"10.34172/ahj.1746","url":null,"abstract":"<p><p>Naltrexone, a long-acting opioid receptor antagonist, is commonly utilized to avert relapse in individuals with opioid or alcohol dependence. While its efficacy in modifying cue-reactivity and lowering desire is well documented, less is known regarding its ability to elicit negative sensory-emotional reactions, particularly in response to olfactory stimulation. We present a rare case of a 16-year-old male with a history of cannabis usage who experienced acute episodes of respiratory distress after starting oral naltrexone (50 mg/day). These episodes were consistently triggered by the smell of opium or cannabis smoke, despite the patient's abstinence. The reactions were severe enough to necessitate multiple emergency medical procedures. The patient had a prior adverse reaction to morphine and a history of multiple drug allergies, suggesting a possible underlying sensitivity to opioid system modulation. The symptoms resolved after discontinuation of naltrexone. This case raises significant clinical and neurobiological concerns about the role of opioid antagonism in modifying olfactory and emotional processing. We propose that naltrexone-induced disinhibition in olfactory-limbic circuits may have contributed to heightened sensory gain and conditioned unpleasant reactions in a sensitized individual. More research is needed to understand the mechanisms driving this unusual yet important reaction.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1746"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges Faced by NGOs in Substance Use Prevention: A Qualitative Study in Ardabil, Iran.","authors":"Saeid Sadeghieh Ahari, Narges Khoshseda, Aziz Kamran","doi":"10.34172/ahj.1699","DOIUrl":"10.34172/ahj.1699","url":null,"abstract":"<p><strong>Introduction: </strong>Non-governmental organizations (NGOs) play a vital role in community-based interventions to prevent and manage substance use disorders. Despite their expanding role, NGOs encounter significant barriers that hinder their effectiveness in Iran. This study aimed to explore the key barriers faced by the NGOs involved in substance use prevention and control in Ardabil Province.</p><p><strong>Methods: </strong>A qualitative conventional content analysis was conducted in 2023, involving in-depth semi-structured interviews with key informants from nine NGOs and community-based organizations actively working in addiction prevention and treatment in Ardabil, northwestern Iran. Data were analyzed using the Graneheim and Lundman method, involving coding, categorization, and theme development. Data collection and analysis were performed concurrently.</p><p><strong>Results: </strong>Analysis revealed three major categories of challenges: (1) Structural and managerial issues, including poor governmental support and limited financial and human resources; (2) Sociocultural challenges, such as stigma towards addiction and low community participation; and (3) Systemic factors that facilitate addiction, including poor inter-sectoral coordination and inconsistent policies. Participants highlighted public distrust and weak collaboration as the major obstacles to effective intervention.</p><p><strong>Conclusion: </strong>Despite the recognized potential of NGOs to enhance community engagement and primary health care efforts in addiction control, they face significant organizational, social, and policy-level barriers in Iran. Strengthening institutional support and fostering greater collaboration between governmental and non-governmental sectors are essential for improving addiction prevention strategies. These findings underscore the need for policy reforms and capacity-building programs to empower NGOs in their mission.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1699"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opium Consumption and Myocardial Infarction in Osteoarthritis Patients: A Propensity Score Matched Cohort Study.","authors":"Mostafa Zarei, Ghobad Moradi, Mojtaba Farjam, Azizallah Dehghan, Bijan Nouri, Daem Roshani","doi":"10.34172/ahj.1676","DOIUrl":"10.34172/ahj.1676","url":null,"abstract":"<p><strong>Introduction: </strong>In recent years, the use of drugs with opioid compounds in patients with osteoarthritis has attracted increasing attention. However, long-term use of these drugs may cause severe side effects, including cardiovascular diseases. The present study aimed to investigate the relationship between the use of opium substances and myocardial infarction in osteoarthritis patients using a propensity score matching (PSM) approach.</p><p><strong>Methods: </strong>We designed this study as a retrospective cohort study. The data were collected from 2016 to 2020. We identified confounding variables using the modified disjunctive cause criterion method. We matched individuals exposed to opium (opium users) and those unexposed to opium (non-users) by propensity score. We examined the distributions of opium users and non-users, both with and without propensity score matching. To determine the relationship between exposure to opium and heart attack in osteoarthritis patients, the Cox regression method was used.</p><p><strong>Findings: </strong>The participants' mean age was 49.85±9.61 years, with 32.3% being men and 67.7% being women. We excluded individuals with cardiovascular disease from the baseline examination. Before PSM, the incidence rate in the total study sample was 2.96 per 1000 person-years. The relationship between opium consumption and heart attack was inverse before matching (hazard ratio, HR 0.73, 95% confidence interval (95% CI 0.58-0.98). After matching, the HR showed an increase of 24% (HR 1.24, 95% CI 0.87-1.76).</p><p><strong>Conclusion: </strong>The findings of the present study suggest that opioid consumption is associated with an increased risk of heart attacks in osteoarthritis patients. Confirmation of this finding in future studies would indicate the need for monitoring these patients with a view towards primary prevention of modifiable cardiovascular risk factors.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1676"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family-centered education vs telephone follow-up on nutrition pattern and Body Mass Index of opioid-dependent patients: A quasi-experimental study.","authors":"Mohsen Hezbollahi, Habib Shareinia, Ali Akbary, Tahereh Baloochi Beydokhti","doi":"10.34172/ahj.1690","DOIUrl":"10.34172/ahj.1690","url":null,"abstract":"<p><strong>Background: </strong>Proper nutrition is important for treatment adherence and preventing adverse metabolic indices in Methadone Maintenance Treatment (MMT) in opioid-dependent patients. The present study aimed to assess the effectiveness of a nutrition education program designed based on the family-centered method and telephone follow-up on nutrition patterns and Body Mass Index (BMI) of opioid-dependent patients undergoing MMT.</p><p><strong>Methods: </strong>In this quasi-experimental study, 60 patients, who had been undergoing MMT for at least one year, at Ibn-e-Sina Psychiatric Hospital of Mashhad, Iran, were selected using the convenience sampling method and assigned to two equal groups (family-centered group and telephone follow-up group) randomly. The participants fulfilled the demographic questionnaire and Food Frequency Questionnaire (FFQ) in pre- and post-test (2 months later), and also the Checklist for recording BMI. Data were analyzed using SPSS version 16, with a significance level of less than 0.05.</p><p><strong>Findings: </strong>The results showed that the two groups had no statistically significant differences in terms of demographic variables. Protein consumption in the family-centered group significantly increased compared to the telephone follow-up group (<i>P</i><0.001). Fat and carbohydrate consumption decreased in both groups, but it was not significant (<i>P</i>>0.05). Also, BMI increased in both groups, but it was not statistically significant (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Based on the results, it seems that family-centered nutrition education is more effective than telephone follow-up, especially to improve protein intake.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1690"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Risk Communication in Predicting Intention to Quit Hookah Smoking.","authors":"Sajjad Narimani, Mehdi Khezeli, Hamed Zandian, Habibeh Matin, Hamid Jafaralilou, Maryam Mazaheri","doi":"10.34172/ahj.1712","DOIUrl":"10.34172/ahj.1712","url":null,"abstract":"<p><strong>Background: </strong>Despite the known harms of hookah smoking, its prevalence is increasing worldwide. Therefore, effective strategies to strengthen cessation efforts are urgently needed. This study aimed to determine the role of risk communication in predicting the intention to quit hookah smoking among Iranian adults.</p><p><strong>Methods: </strong>This cross-sectional study was conducted with 485 hookah smokers aged 18 to 59 years from Kermanshah (western Iran) and Ardabil (northwestern Iran). A cluster sampling method was used to select hookah-smoking venues, and simple random sampling was applied to recruit participants. Data were collected using a demographic form, a questionnaire based on the Extended Parallel Process Model (EPPM), and a health warning questionnaire. Multiple linear regression was used to determine the predictors of intention to quit hookah smoking.</p><p><strong>Findings: </strong>The mean age of participants was 30.24±8.29 years. The health warning was the strongest predictor of the intention to quit hookah smoking (β=0.359, <i>P</i><0.001). Among EPPM constructs and demographic variables, defensive motivation (β=-0.142, <i>P</i>=0.016), self-efficacy (β=0.139, <i>P</i>=0.016), perceived severity (β=0.128, <i>P</i>=0.032), and age (β=0.140, <i>P</i>=0.009) were significant predictors. The final regression model explained approximately 36% of the variance in intention to quit hookah (Adj-R²=0.356).</p><p><strong>Conclusion: </strong>The health warning was the strongest predictor of intention to quit hookah smoking, highlighting the importance of targeted risk communication. Defensive motivation, perceived severity, self-efficacy, and age were other significant predictors. Public education programs should focus on increasing perceived severity, enhancing self-efficacy, and reducing defensive motivation, especially targeting younger populations to curb hookah use.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1712"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Cross-Sectional Study on Methadone Poisoning: A Decade of Insights from Kerman, Iran.","authors":"Motahareh Soltani, Mohammad Mahdi Ghanbari, Somayyeh Karami-Mohajeri, Zohreh Oghabian, Mohammed Mahdi-Abdulameer, Maryam Dalili, Soudeh Khanamani Falahati-Pour","doi":"10.34172/ahj.1678","DOIUrl":"10.34172/ahj.1678","url":null,"abstract":"<p><strong>Introduction: </strong>Methadone poisoning, involving both syrup and tablet formulations, represents a significant public health concern, particularly in regions where methadone is widely utilized for opioid substitution therapy. Methadone accounted for approximately 16% of pediatric acute poisonings and was the leading cause of drug-related deaths in 2023. This study provides a decade-long retrospective analysis of methadone poisoning cases in Kerman, Iran, with a focus on demographic patterns, clinical outcomes, and risk factors to guide prevention and treatment strategies.</p><p><strong>Methods: </strong>This retrospective cross-sectional study reviewed medical records of 5,826 methadone poisoning cases, primarily acute but including some chronic cases, admitted to Afzalipour Hospital between 2013 and 2023. Data on demographics, clinical presentations, comorbidities, and outcomes were analyzed using SPSS version 22, with statistical significance set at <i>P</i><0.05.</p><p><strong>Results: </strong>The majority of patients were male (63.5%), with the highest prevalence among individuals aged 19-40 years (45.3%). Notably, 17.7% of cases involved children under six years old, primarily due to accidental ingestion linked to unsafe storage practices. Intentional poisoning accounted for 80.2% of cases, underscoring the role of mental health and socio-economic factors. Co-intoxication with benzodiazepines (9.8%) and alcohol (4.9%) exacerbated toxicity, while 8.8% of cases coincided with COVID-19 infection, compounding respiratory complications. The mortality rate was low at 1.9% (95% CI: 1.6-2.2%), with 63.8% of cases achieving full recovery; and notably, 17.7% of cases involved were children aged under six years old.</p><p><strong>Conclusion: </strong>The findings, including high co-intoxication risks with benzodiazepines (9.8%) and alcohol (4.9%), highlight the urgent need for targeted interventions, including stricter regulation of methadone distribution, childproof packaging, and public education campaigns to reduce accidental pediatric poisonings. Integrated mental health services are critical to addressing intentional poisoning cases (80.2%), while healthcare providers should remain vigilant about polysubstance use. These strategies can significantly reduce methadone-related morbidity and mortality, especially among vulnerable populations such as children and young adults.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1678"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Ritalin Abuse and its Relationship with Demographic Characteristics Among Medical Students: A Cross-Sectional Study.","authors":"Arian Karimi Rouzbahani, Samaneh Tahmasebi Ghorabi, Faezeh Abbasi, Ahad Fazeli","doi":"10.34172/ahj.1555","DOIUrl":"10.34172/ahj.1555","url":null,"abstract":"<p><strong>Introduction: </strong>Substance abuse is a significant global issue, particularly among professional doctoral students who have increased access to medications like Ritalin. The misuse of Ritalin among this population poses substantial risks. Hence, understanding its prevalence and reasons is crucial. The purpose of this study was to assess the prevalence of Ritalin abuse among professional doctoral students at Lorestan University of Medical Sciences and investigate its relationship with demographic characteristics.</p><p><strong>Methods: </strong>This study is a descriptive-analytical cross-sectional investigation involving 320 professional doctoral students at Lorestan University of Medical Sciences during the 2022-2023 academic year. A checklist was employed to assess the prevalence of Ritalin usage and its correlation with demographic factors. The acquired data were analyzed using SPSS version 22.</p><p><strong>Findings: </strong>The study found that 10.6% of the students surveyed were misusing Ritalin. Most participants were female (56.9%) and were studying medicine (70%). A significant proportion had a good income level (38.8%), and clinical professional doctoral students had the highest rate of Ritalin misuse (52.9%). Gender, educational level, place of residence, and marital status showed significant associations with Ritalin misuse (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Misuse of Ritalin among professional doctoral students (pharmacy, medicine, dentistry) at Lorestan University of Medical Sciences is widespread. Consequently, due to the negative impacts and issues stemming from unjustified and self-administered Ritalin misuse, strict control and supervision in drug distribution and sales are imperative, along with measures to deter non-prescription sales.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"18 ","pages":"1555"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13678038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacokinetics of Dual Amino Acids for Dry Powder Inhalation Therapy in Pulmonary Drug Delivery: An In-Vivo Study.","authors":"Mani Abinaya, Sellappan Mohan, Arumugam Nagarajan","doi":"10.34172/ahj.1538","DOIUrl":"10.34172/ahj.1538","url":null,"abstract":"<p><strong>Background: </strong>Smoking cigarettes leads to serious health problems, and addiction is a major concern. De-addiction therapy includes e-cigarettes and counseling, and the success rate is poor in these approaches, warranting alternate therapeutic interventions. The present study evaluates dry powder inhalation using amino acids as a new method.</p><p><strong>Methods: </strong>A novel formulation was prepared using nanospray drying and ball milling techniques. SEM analysis was conducted to ascertain particle size, and pharmacokinetic assessment was done to evaluate how rapidly the drug is released from the formulation. The optimized ratio of ingredients revealed the best formula, L-tyrosine, L-tryptophan, and lactose in the ratio of 5 mg:1 mg: 4 mg, which led to the dry powder preparation. SEM analysis revealed that the dry powder comprising L-tryptophan and L-tyrosine had undergone micronization to 2-4 µm.</p><p><strong>Findings: </strong>An innovative treatment, such as an inhalation powder therapy comprising amino acids, can help reduce mood changes. Depletion of tryptophan to kynurenine controls mood changes, and maintaining a steady tryptophan concentration is expected to help overcome mood changes that trigger smoking recurrence. The microparticles produced by spray-drying were confirmed to include loose agglomerates, which are amenable to inhalation and free dispersion. In-vivo studies revealed that drug action is quick with drug delivery and retention at the site of action.</p><p><strong>Conclusion: </strong>The synergistic effect of the novel formulation's sustained concentration of tryptophan and tyrosine and inhibition of AChE could diminish the recurrence of smoking. Dry powder inhalation of the formulated drug offers a new and strong method of drug delivery to the alveolus, making it a convenient route of administration that could be superior to other modes of administration in smoking cessation.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1538"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Resilience-Based Intervention on Post-traumatic Growth, Resilience, Coping Skills, and Perceived Stress in Women with Addicted Spouses.","authors":"Akram Ahmadzadeh, Mohammad Saeed Khanjani, Manoochehr Azkhosh, Seyyed Jalal Younesi, Gholamreza Ghaedamini Harouni","doi":"10.34172/ahj.1510","DOIUrl":"10.34172/ahj.1510","url":null,"abstract":"<p><strong>Background: </strong>Substance abuse, as a major global issue, not only affects individuals but also impacts family members, particularly women. Meanwhile, post-traumatic growth and resilience are important factors in the recovery process for these women. Therefore, the aim of this study was to investigate the effectiveness of a resilience-based intervention in facilitating post-traumatic growth among women with addicted spouses.</p><p><strong>Methods: </strong>A randomized clinical trial was conducted involving women with addicted partners (<i>n</i>=30) in Qom during the years 2021 and 2022. Participants were randomly allocated to the two groups of intervention and control. A demographic information form, post-traumatic growth questionnaire, resilience scale, perceived stress scale, and the Connor-Davidson coping skills questionnaire, were used to collect data at pre-test, post-test, and follow-up (three months later). Data analysis was conducted using SPSS software (version 22.0), with a significance level of <i>P</i><0.05.</p><p><strong>Findings: </strong>The findings demonstrated a significant increase in scores of resilience (<i>η</i> ²=0.015), post-traumatic growth (<i>η</i> ²=0.185), emotion-focused coping skills (<i>η</i> ²=0.253), and problem-focused coping skills (<i>η</i> ²=0.131) in the intervention group between pre-test, post-test, and follow-up stages (<i>P</i><0.001). However, the intervention did not influence perceived stress (<i>η</i> ²=0.017) (<i>P</i>=0.473). No significant changes were observed in these variables in the control group.</p><p><strong>Conclusion: </strong>The findings showed that the resilience intervention resulted in enhanced post-traumatic growth, coping abilities, and resilience in women with addicted spouses. Implementing this intervention in mental health centers and addiction recovery programs not only enhances the mental well-being of these women but also contributes to the psychological well-being of their families.</p>","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1510"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}