Infection Prevention in Practice最新文献

{"title":"Device associated healthcare associated infection (DA-HAI): a detailed analysis of risk factors and outcomes in a university hospital in Rome, Italy","authors":"Luca Guarente ,&nbsp;Claudia Mosconi ,&nbsp;Mariagrazia Cicala ,&nbsp;Carolina De Santo ,&nbsp;Fausto Ciccacci ,&nbsp;Mariachiara Carestia ,&nbsp;Leonardo Emberti Gialloreti ,&nbsp;Leonardo Palombi ,&nbsp;Giuseppe Quintavalle ,&nbsp;Daniele Di Giovanni ,&nbsp;Ersilia Buonomo ,&nbsp;Stefania Moramarco ,&nbsp;Fabio Riccardi ,&nbsp;Stefano Orlando","doi":"10.1016/j.infpip.2024.100391","DOIUrl":"10.1016/j.infpip.2024.100391","url":null,"abstract":"<div><h3>Introduction</h3><p>This study investigates the impact of invasive procedures on healthcare-associated infections (HAI) at Policlinico Universitario Tor Vergata in Rome, Italy, aiming to understand their role in device-associated HAI and to inform prevention strategies.</p></div><div><h3>Methods</h3><p>A retrospective cohort analysis was conducted, examining mandatory discharge records and microbiology data from 2018 across all departments. The study focused on adult patients, analysing the correlation between invasive procedures and HAI through univariate and multivariate logistic regression.</p></div><div><h3>Results</h3><p>Of the 12,066 patients reviewed, 1,214 (10.1%) experienced HAI. Univariate analysis indicated an association between invasive procedures and HAI (OR = 1.81, <em>P</em> &lt; 0.001), which was not observed in multivariable analysis. Specific procedures significantly raised HAI risks: temporary tracheostomy (AOR = 22.69, <em>P</em> &lt;0.001), central venous pressure monitoring (AOR = 6.74, <em>P</em> &lt;0.001) prolonged invasive mechanical ventilation (AOR = 4.44, <em>P</em> &lt;0.001), and venous catheterisation (AOR = 1.58, <em>P</em> &lt;0.05). Aggregated high-risk procedures had an increased likelihood of HAI in multivariable analysis (OR = 2.51, <em>P</em> &lt; 0.001). High-risk departments were also notably associated with HAI (OR = 6.13, <em>P</em> &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>This study suggests that specific invasive procedures, such as temporary tracheostomy, significantly increase HAI risks. The results highlighting the need for targeted infection prevention and control procedures and supports the need for innovative methods such as record-linkage in policymaking to address HAI. These findings inform clinical practice and healthcare policy to improve patient safety and care quality.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 4","pages":"Article 100391"},"PeriodicalIF":1.8,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000556/pdfft?md5=43d7c06fec6ad516bbc45fda70374095&pid=1-s2.0-S2590088924000556-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142238686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the antimicrobial effect of a far-uv radiation lamp in a real-life environment","authors":"Szava Bansaghi ,&nbsp;Jörn Klein","doi":"10.1016/j.infpip.2024.100390","DOIUrl":"10.1016/j.infpip.2024.100390","url":null,"abstract":"<div><h3>Background</h3><p>Using far-Ultraviolet-C (UVC) radiation with an emission maximum of 222 nm, has the potential to kill bacteria while not being harmful to humans and can be used continuously in public areas. Elevators pose a high risk of infection transmission, as they are small, crowded spaces with poor ventilation. In such a setting continuous decontamination would be very useful. This study aimed to measure the effectiveness of a far-UVC lamp installed in a frequently used elevator by comparing the bacterial load found in that elevator with the bacterial load in a control elevator.</p></div><div><h3>Methods</h3><p>Microbial load was measured by different methods; ATP bioluminescence, surface samples were collected by contact slides, contact plates, and swabbing. Air samples were also collected.</p></div><div><h3>Results</h3><p>No significant differences were found in the microbial content between the control elevator and the UV-lamp elevator, regardless of whether the UV-lamp was always on, or was used with a motion sensor to turn off when someone entered the elevator.</p></div><div><h3>Conclusions</h3><p>The results suggest that the far-UVC requires a longer time to kill the bacteria, while the people traffic were continuously re-contaminating the elevators.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 4","pages":"Article 100390"},"PeriodicalIF":1.8,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000544/pdfft?md5=29655e69d51ea531cc3d3b154d3c0331&pid=1-s2.0-S2590088924000544-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142096080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airborne SARS-CoV-2 RNA detected during deliveries with unmasked patients","authors":"Sara Thuresson ,&nbsp;Malin Alsved ,&nbsp;Åsa Leijonhufvud ,&nbsp;Andreas Herbst ,&nbsp;Patrik Medstrand ,&nbsp;Jakob Löndahl ,&nbsp;Carl-Johan Fraenkel","doi":"10.1016/j.infpip.2024.100389","DOIUrl":"10.1016/j.infpip.2024.100389","url":null,"abstract":"<div><h3>Background</h3><p>Healthcare workers in obstetric clinics may be exposed to airborne SARS-CoV-2 when treating patients with COVID-19.</p></div><div><h3>Method</h3><p>In this study, performed during the midst of the pandemic, air samples were collected in delivery rooms during childbirth and analysed for SARS-CoV-2 RNA content.</p></div><div><h3>Result</h3><p>Six of 28 samples collected inside delivery rooms were positive for SARS-CoV-2, but none in anterooms or corridors. Five of the six positive samples were from the same occasion.</p></div><div><h3>Discussion</h3><p>This indicates that some patients could be major sources of exhaled virus, although the individual variation is large, and it is thus difficult to predict the risk of infection.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 4","pages":"Article 100389"},"PeriodicalIF":1.8,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000532/pdfft?md5=ed47fc1c05c49b6fa552d8211d8b0c9d&pid=1-s2.0-S2590088924000532-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142135976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital-acquired respiratory viral infections while applying droplet precautions on-site (DroPS) - prospective observation during the 2019/20 influenza season, Bern, Switzerland","authors":"Michèle Birrer ,&nbsp;Katrien Draps ,&nbsp;Fabienne Hobi ,&nbsp;Marianne Laguardia ,&nbsp;Eveline Hofmann ,&nbsp;Martin Luginbühl ,&nbsp;Martin Perrig ,&nbsp;Drahomir Aujesky ,&nbsp;Jonas Marschall ,&nbsp;Rami Sommerstein","doi":"10.1016/j.infpip.2024.100386","DOIUrl":"10.1016/j.infpip.2024.100386","url":null,"abstract":"<div><p>Single room isolation for respiratory viral infections (RVI), like influenza, puts hospitals under pressure. During the influenza season 2019/20, we implemented <em>Droplet precautions on-site</em> (DroPS) for RVI in two acute care hospitals and prospectively assessed the rate of hospital-acquired RVI (HARVI). 318 patients were admitted with RVI, 85 had Influenza or RSV, 75 stayed in multi-bed rooms with DroPS. From 764 patients <em>at risk</em>, hospitalised ≥ three days in a multi-bed room<em>,</em> 11 (1.4%) developed a clinical HARVI, and three tested positive (3/764, 0.4%; 2x RSV, 1x influenza). DroPS may represent an alternative strategy to deal with respiratory viral infections.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100386"},"PeriodicalIF":1.8,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000507/pdfft?md5=080f9af36a9f99f276333294824106dd&pid=1-s2.0-S2590088924000507-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection prevention and control factors associated with post-cataract surgery endophthalmitis - a review of the literature from 2010 – 2023","authors":"O.A. Saba,&nbsp;Y. Benylles,&nbsp;M.H. Howe,&nbsp;T. Inkster,&nbsp;E.L. Hooker","doi":"10.1016/j.infpip.2024.100387","DOIUrl":"10.1016/j.infpip.2024.100387","url":null,"abstract":"<div><p>Patients undergoing cataract surgery are at risk of post-cataract surgery endophthalmitis (PCSE), a sight-threatening complication. Cataract surgery is a relatively straightforward and quick procedure often performed under local anaesthetic. It is therefore simple to scale up to reduce the currently long waiting times, but it is important to maintain patient safety when considering high throughput surgery. This literature review aimed to identify appropriate infection prevention and control (IPC) measures to support increased throughput of cataract surgery in Scotland. Database searches were conducted using Medline and Embase from 2010 to 2023. Further hand-searching was also performed. The organisms associated with PCSE and IPC factors relevant to PCSE were analyzed. A range of microorganisms was associated with PCSE, where outbreak reports were most associated with Gram-negative bacteria and fungi, whereas retrospective chart reviews were most associated with Gram-positive bacteria. IPC risk factors identified were related to the built environment and issues with sterilization. Specifically, the sources of outbreaks included failures in the ventilation system, as well as contaminated ophthalmic solutions, surgical instruments, and medications. The factors identified in this review should be considered when implementing high throughput cataract surgery to ensure that patient safety is maintained.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100387"},"PeriodicalIF":1.8,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000519/pdfft?md5=1777309c5f718f20deed0f7b67065b99&pid=1-s2.0-S2590088924000519-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic stewardship: establishing the role of the hospital nurse to inform local engagement strategies","authors":"Sue Bowler ,&nbsp;Jo Brown","doi":"10.1016/j.infpip.2024.100381","DOIUrl":"10.1016/j.infpip.2024.100381","url":null,"abstract":"<div><h3>Background</h3><p>Diagnostic stewardship is ‘coordinated guidance and interventions to improve appropriate use of microbiological diagnostics to guide therapeutic decisions’ and a fundamental part of antimicrobial stewardship and the nursing role. The role of the nurse in diagnostic stewardship is relatively unknown and an underused resource. Lack of involvement and training in diagnostic stewardship can lead to inaction or incorrect actions, either of which may be detrimental to patient management, outcomes and care.</p></div><div><h3>Aim</h3><p>To determine the role of the hospital adult nurse in diagnostic stewardship to inform local engagement strategies.</p></div><div><h3>Methods</h3><p>The methodology was informed by Whiffin's (2020) systematic search approach. Electronic databases were searched from 2016 to 2022. The studies included were primary research papers involving adult nurses working in a hospital setting, with findings relevant to a diagnostic stewardship role. Thematic analysis was chosen to understand and compare the results, findings and recommendations of the studies.</p></div><div><h3>Findings</h3><p>Seven studies were included in the review. The identified themes were: (i) nursing role – to recognize infection, aid diagnosis and review results; (ii) nurse challenges – lack of knowledge and confidence to implement diagnostic stewardship; and (iii) Nurse education, empowerment and use of clinical tools.</p></div><div><h3>Conclusion</h3><p>Research studies do not consistently recognize the full scope of the diagnostic stewardship nursing role, signifying that nurses remain an underused resource in promoting diagnostic stewardship. Research-based clarification of the role of the nurse in diagnostic stewardship, outlined in this review, is therefore vital. Further UK-based, nurse-led research is needed to capture the impact of nurse-driven diagnostic stewardship interventions.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100381"},"PeriodicalIF":1.8,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000453/pdfft?md5=09a3e76733890c6cc6531202bde91314&pid=1-s2.0-S2590088924000453-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How did the COVID-19 pandemic affect antibiotic consumption within humanitarian emergencies? Results from five humanitarian contexts","authors":"Tuba Yavuz ,&nbsp;Kate Clezy ,&nbsp;Kristina Skender ,&nbsp;Jacob Goldberg ,&nbsp;Frédérique Vallières","doi":"10.1016/j.infpip.2024.100385","DOIUrl":"10.1016/j.infpip.2024.100385","url":null,"abstract":"<div><h3>Introduction</h3><p>Both high- and low-income countries reported increased antibiotic consumption among COVID-19 patients during the first months of the pandemic. To date, however, no studies have examined changes in antibiotic consumption during the COVID-19 pandemic within humanitarian emergency contexts.</p></div><div><h3>Method</h3><p>Data was collected by Médecins Sans Frontières (MSF) for the years 2018–2021 across the following humanitarian settings: Afghanistan (Lashkar Gah), Bangladesh (Kutupalong), the Democratic Republic of Congo (Mweso and Baraka), and South Sudan (Bentiu). Inpatient and outpatient antibiotic consumption was calculated as Daily Defined Dose (DDD) per 1000 inhabitants per day, as per the World Health Organisation's (WHO) Collaborating Centre for Drug Statistics Methodology. Interrupted time series (ITS) analysis, using an autoregressive integrated moving average (ARIMA) model was used to analyse retrospective monthly antibiotic consumption. The impact of COVID-19 pandemic was evaluated as total antibiotic consumption and according to WHO Access, Watch, Reserve (AWaRe) group classifications within each humanitarian setting.</p></div><div><h3>Results</h3><p>The COVID-19 pandemic had no statistically significant impact on total antibiotic consumption in South Sudan (Bentiu) and Bangladesh (Kutupalong). Similarly, the pandemic had no impact on total antibiotic consumption in DR Congo (Baraka), despite an initial 0.27% (estimate=.274, p-value=0.006) increase in March 2020 driven by Access group antibiotics. Meanwhile, total antibiotic consumption in DR Congo (Mweso) and Afghanistan (Lashkar Gah) declined by 0.74% (estimate = −.744, p = 0.003) and 0.26% (estimate = −.26, p &lt; 0.001), respectively with the COVID-19 pandemic.</p></div><div><h3>Conclusion</h3><p>Further studies are required to investigate what may have contributed to these results.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100385"},"PeriodicalIF":1.8,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000490/pdfft?md5=5ad2a6afb432bb553d59c9b69d07fad7&pid=1-s2.0-S2590088924000490-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Tree of Life: assessing the efficacy of microbiology teaching for foundation year doctors","authors":"Ajay Bowry ,&nbsp;Aiden J. Plant","doi":"10.1016/j.infpip.2024.100384","DOIUrl":"10.1016/j.infpip.2024.100384","url":null,"abstract":"","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100384"},"PeriodicalIF":1.8,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000489/pdfft?md5=9626150ecd5b8a44c164d69fd3965071&pid=1-s2.0-S2590088924000489-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing","authors":"Hanno Schmidt ,&nbsp;Niels Lemmermann ,&nbsp;Matthias Linke ,&nbsp;Sven-Ernö Bikár ,&nbsp;Stefan Runkel ,&nbsp;Susann Schweiger-Seemann ,&nbsp;Susanne Gerber ,&nbsp;André Michel ,&nbsp;Thomas Hankeln ,&nbsp;Marina Veith ,&nbsp;Wolfgang Kohnen ,&nbsp;Bodo Plachter","doi":"10.1016/j.infpip.2024.100383","DOIUrl":"10.1016/j.infpip.2024.100383","url":null,"abstract":"<div><h3>Background</h3><p>During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and therapeutics. SARS-CoV-2 variant monitoring by whole genome sequencing was established at the University Medical Center Mainz, Germany to support patient management during the pandemic.</p></div><div><h3>Methods</h3><p>SARS-CoV-2 RNA samples from the University Medical Center were analysed weekly with whole genome sequencing. The genome sequences obtained were aligned with sequences from public databases to perform variant assignment. For classification purposes, phylogenetic trees were constructed to map the variant distribution in the clinical settings and the current outbreak events at that time. We describe the surveillance procedures using an example from a geriatric ward.</p></div><div><h3>Results</h3><p>For monitoring, a time series was created covering two years of the pandemic. The changes from the Alpha to the Delta and the Omicron variants of SARS-CoV-2 could thus be precisely observed. The increasingly rapid switch of Omicron subvariants in the recent past could be tracked. The elucidation of phylogenetic relationships between circulating strains allowed conclusions about transmission pathways. Using an example from a geriatric ward, we demonstrated how variant monitoring by whole genome sequencing supported the infection prevention and control procedures on a ward and contribute to the control of outbreaks.</p></div><div><h3>Conclusions</h3><p>This example of SARS-CoV-2 demonstrates the effectiveness of targeted, local monitoring by molecular variant analysis. The program proved to be instrumental in controlling an outbreak on a geriatric ward.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100383"},"PeriodicalIF":1.8,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000477/pdfft?md5=7f2e12844b2c8865f36edf4ce8fb22de&pid=1-s2.0-S2590088924000477-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital epidemiology: harnessing big data for early detection and monitoring of viral outbreaks","authors":"Deema Ibrahim Fallatah ,&nbsp;Hafeez Aderinsayo Adekola","doi":"10.1016/j.infpip.2024.100382","DOIUrl":"https://doi.org/10.1016/j.infpip.2024.100382","url":null,"abstract":"<div><p>Digital epidemiology is the process of investigating the dynamics of disease-related patterns, both social and clinical, as well as the causes of these trends in epidemiology. Digital epidemiology, utilising big data from a variety of digital sources, has emerged as a viable method for early detection and monitoring of viral outbreaks. The present review gives an overview of digital epidemiology, emphasising its importance in the timely detection of infectious disease outbreaks. Researchers may discover and track outbreaks in real time using digital data sources such as search engine queries, social media trends, and digital health records. However, data quality, concerns about privacy, and data interoperability must be addressed to maximise the effectiveness of digital epidemiology. As the global landscape of infectious diseases evolves, integrating digital epidemiology becomes critical to improving pandemic preparedness and response efforts. Integrating digital epidemiology into routine monitoring systems has the potential to improve global health outcomes and save lives in the event of viral outbreaks.</p></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"6 3","pages":"Article 100382"},"PeriodicalIF":1.8,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590088924000465/pdfft?md5=e05f6a6d77c5330cfbb64071abca868d&pid=1-s2.0-S2590088924000465-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141594820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}