Virology & Immunology Journal最新文献

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Effects of COVID-19 Outbreaks on Livestock Sector COVID-19疫情对畜牧业的影响
Virology & Immunology Journal Pub Date : 2020-11-19 DOI: 10.23880/vij-16000258
Singh Nk
{"title":"Effects of COVID-19 Outbreaks on Livestock Sector","authors":"Singh Nk","doi":"10.23880/vij-16000258","DOIUrl":"https://doi.org/10.23880/vij-16000258","url":null,"abstract":"A like others, livestock industries are badly affected during lockdown periods due to COVID-19 pandemic. The COVID-19 disease outbreak was originated in Wuhan city of Hubei province of China during the month of December 2019. On the basis of whole virus genome sequence analysis and other phylogenetic characteristics, International Committee on Taxonomy of Viruses (ICTV) group classified that COVID-19 is a caused by Severe Acute Respiratory Syndrome coronavirus-2 (SARS Cov2). Its genome sequence homology analysis also revealed that the nucleotides sequence of human corona virus (SARS Cov-2 virus) is 87.5% - 96.3% similar to corona viruses of bat’s origin. During lockdowns, it is relatively easy to close down the factories, IT parks, hotels, Shopping malls and multiplexes but it is not so easy with agriculture and animal husbandry; these sectors will continue to produce.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134318691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception, Attitude and Practice of Personal Protective Measures by Nigerians during the COVID-19 Outbreak: An Online Cross-Sectional Study 2019冠状病毒病暴发期间尼日利亚人对个人防护措施的认知、态度和实践:一项在线横断面研究
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000253
Ugwu Mc
{"title":"Perception, Attitude and Practice of Personal Protective Measures by Nigerians during the COVID-19 Outbreak: An Online Cross-Sectional Study","authors":"Ugwu Mc","doi":"10.23880/vij-16000253","DOIUrl":"https://doi.org/10.23880/vij-16000253","url":null,"abstract":"Objective: People’s compliance to control measures is dependent on their perception, attitudes and practices towards COVID-19. This survey evaluated the perception, attitude and practice of personal protective measures by Nigerians during the COVID-19. Methods: This was a cross-sectional study using an internet-based survey/questionnaire. A total of 731 Nigerians (male and female: age >14 years) were selected between April 15 and 26, 2020 to complete an online survey. Results: Majority (> 50 %) of the participants in all the geopolitical zones would always wash their hands with soap and/ use hand sanitizers. Many of the participants (>40%) across all the zones self-reported that they always wash their hands with soap and use hand sanitizer after a hand shake. More than 70 % of the participants had at least Bachelors degree. Majorities are civil servants and mostly obtain their COVID-19 information from WhatsApp (71.4%), Television (65.3%) and National Centre for Disease Control (NCDC) (62.5%).","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117205745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence Along with Diagnostic Modalities and Treatment of Female Infertility Due to Female Genital Disorders 女性生殖器疾病导致的女性不孕症的患病率、诊断方式和治疗
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000249
Naeem F
{"title":"Prevalence Along with Diagnostic Modalities and Treatment of Female Infertility Due to Female Genital Disorders","authors":"Naeem F","doi":"10.23880/vij-16000249","DOIUrl":"https://doi.org/10.23880/vij-16000249","url":null,"abstract":"Infertility is a communal pathological ailment now-a-days worldwide and approximately females are mostly suffering from this condition. In previous studies, out of 2.4 million married couples have females in between the ages from 15-44 year; 1.0 million couples were suffering from primary infertility and 1.4 million couples had secondary infertility. The infertility causes are ovulatory factors, dietary factors, psychological factors, abnormal endocrine functions, fallopian tube disorders etc. PCOS, PIDs, endometriosis. The ultrasonography is the most powerful tool for diagnosis. The treatment involves medical, surgical and assisted reproduction. Medical treatment includes clomiphene, metformin, iron & folic acid supplements along with oralcontraceptives. Surgical treatment is operative laparoscopy and assisted reproduction is achieved by IVF, GIFT & IUI etc. It is concluded from the study that the percentage prevalence of female infertility among ages was higher in age group (25-34) years (76%) and it was mostly secondary infertility (54%). The main pathological factor of female infertility in Sialkot city was PCOS, which was 52% of evaluated patients. Commonly used diagnostic tools were ultrasonography with prevalence of 100% and endocrine tests (72%). In prescription trend, anti-obesity drugs, anti-oestrogen drugs and oral-contraceptives were commonly prescribed and other treatment interventions were also seen in few patients.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126508308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sperm Cell Damage Induced by Urogenital Tract Infections 泌尿生殖道感染引起的精子细胞损伤
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000255
K. V.
{"title":"Sperm Cell Damage Induced by Urogenital Tract Infections","authors":"K. V.","doi":"10.23880/vij-16000255","DOIUrl":"https://doi.org/10.23880/vij-16000255","url":null,"abstract":"Male infertility has traditionally been diagnosed by microscopic assessment of concentration, motility and morphology of sperm in the ejaculate. These tests are essential to provide the fundamental information on sperm quality. However, evidence based medicine shows that sperm DNA fragmentation (SDF) tests can also differentiate fertile from infertile males.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121747773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanotechnology: An Aid to Human Welfare in COVID-19 Pandemic Era 纳米技术:COVID-19大流行时代人类福祉的援助
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000252
Tripathi M
{"title":"Nanotechnology: An Aid to Human Welfare in COVID-19 Pandemic Era","authors":"Tripathi M","doi":"10.23880/vij-16000252","DOIUrl":"https://doi.org/10.23880/vij-16000252","url":null,"abstract":"The novel coronavirus disease 2019 (COVID-19) outbreak has led to a worldwide demand for efficacious identification and medication as well as preventing the spread of infection. Based on an abundance of engineered materials recognizable through their useful physicochemical properties, nanotechnology provides a number of perspectives to tackle with this pandemic disease. Nanotechnology can aid to fight against COVID-19, infectious diseases in general, as well as future pandemics. It works on nano scale level ranging from 0 to 100 nanometers. Nanoparticles are small in size but they have greater surface area in comparison to large sized molecules which increase its efficiency. The technology has potential to manipulate the molecules in our desired nature. Nanoparticles are used in almost every area for human welfare. It can be also be a useful tool for the treatment of COVID-19 outbreak like development of rapid detection kits for the testing of COVID-19 infection. Nano biotechnology may also be helpful to cure many other chronic diseases, in development of improved personal protective equipment including facemasks, effective vaccines and targeted drug delivery systems. Summarily, nanotechnology can be crucial in preventing COVID-19 and future pandemics.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128056599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Possible Use of Ganoderma Mushroom Extracts for the Treatment of Some Chronic Risk Factors Associated with Severe Covid-19 灵芝提取物可能用于治疗与严重Covid-19相关的一些慢性危险因素
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000254
Ohimain Ei
{"title":"Possible Use of Ganoderma Mushroom Extracts for the Treatment of Some Chronic Risk Factors Associated with Severe Covid-19","authors":"Ohimain Ei","doi":"10.23880/vij-16000254","DOIUrl":"https://doi.org/10.23880/vij-16000254","url":null,"abstract":"The novel coronavirus (SARS-CoV-2) emerged in Wuhan, China in December 2019 causing the coronavirus disease 2019 (COVID-19). The disease has caused a pandemic that had disrupted social and economic life globally. Intense research is ongoing to understand the nature of the virus and pathogenesis as well as the development of drugs and vaccines. Ample evidence suggests that the elderly people, those with pre-existing chronic medical conditions, such as lung disease, heart disease, diabetes, obesity, chronic kidney disease, compromised immunity and even men may be at higher risk of serious illness and intensive care. The virus tends to trigger the over-production of pro-inflammatory cytokines, which results in multiorgan damage, resulting in death. Following this review, we proposed the use of Ganoderma mushroom extracts, which have certain properties relevant to the management of COVID-19 complications including anti-inflammatory, antiviral, immune modulatory, and antioxidant, anti-aging and multiorgan protection. Most of this research has been done on rodent models with few clinical trials. Since, the mushroom is generally regarded as safe (GRAS) and have been used for centuries in Asian traditional medicine, we recommend the use of this mushroom in the management of the disease including as active ingredients in COVID-19 drugs, and alternatives to synthetic drugs, health supplements, adjuvant therapy or functional foods.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128799751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prevalence of Hepatitis Delta Virus in Hemodialysis Patients with Hepatitis B Virus in Benghazi, Libya as Starting Point 以利比亚班加西乙型肝炎病毒血液透析患者中丁型肝炎病毒的流行为起点
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000250
Attitalla Ih
{"title":"Prevalence of Hepatitis Delta Virus in Hemodialysis Patients with Hepatitis B Virus in Benghazi, Libya as Starting Point","authors":"Attitalla Ih","doi":"10.23880/vij-16000250","DOIUrl":"https://doi.org/10.23880/vij-16000250","url":null,"abstract":"Hepatitis delta virus (HDV) is a subviral satellite RNA virus. It is consisting of approximately 1700 nucleotides long genomic circular RNA with one open reading frame encoding for two proteins (small delta antigens (HDAg-S) and large delta antigens (HDAg-L) coated with Hepatitis B virus (HBV) surface antigen (HBsAg). HDV was discovered in 1977 in an Italian patient who had chronic HBV infection. HDV infection is of particular concern in hemodialysis (HD) units due to HD patient’s segregation into groups, lack of HDV diagnosis, irreversible complications of the infection, and controversial treatments. Several different studies were conducted in different parts of the world to explore the prevalence HDV in HD patients. The prevalence was ranging from zero to 58%. In France HDV infection in chronic HD and kidney transplant patients was zero. HDV antibody was detected in 1.7% of HD and renal transplantation patients in Brazil. In Khartoum State, Sudan prevalence of HDV among hepatitis B patients on HD was 13.3%. The prevalence of HDV in HD patients in Iran was 44.5%. HDV antibody was positive in 58% of the HD patients in Menoufiya, Egypt there is no study so far conducted on the prevalence of HDV in HD patients in Libya. The aim of this study was to call for medical personal managing HD units to apply new restriction rolls in managing their work environments for the wellbeing of their patients.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115919176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Covid19 the Virus Immunology and Blood Coagulation, a Positive Feedback Cycle with Resultant Pathogenesis: A Perspective covid - 19病毒免疫学和血液凝固:一个正反馈循环及其发病机制的视角
Virology & Immunology Journal Pub Date : 2020-09-08 DOI: 10.23880/vij-16000251
G. K
{"title":"Covid19 the Virus Immunology and Blood Coagulation, a Positive Feedback Cycle with Resultant Pathogenesis: A Perspective","authors":"G. K","doi":"10.23880/vij-16000251","DOIUrl":"https://doi.org/10.23880/vij-16000251","url":null,"abstract":"Covid 19 is a new beta corona virus which is driving the present pandemic across the world. The virus is highly transmissible through respiratory route with a Ro value varying between1.3-2.0. The virus is a direct strand RNA virus and is one of the largest viruses of RNA virus group. It has 11 open reading frame of which ORF 9-11 is involved in translation of structural S (Spike), E (Envelop), M (Matrix) and N (Nucleocapsid) glycoproteins. Of these S protein is very important from the point of view of virus engagement with the host cell and its infectivity.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132811039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV and SARS-Cov-2 the Dilemma 艾滋病毒和SARS-Cov-2的困境
Virology & Immunology Journal Pub Date : 2020-07-02 DOI: 10.23880/vij-16000248
Abreu C
{"title":"HIV and SARS-Cov-2 the Dilemma","authors":"Abreu C","doi":"10.23880/vij-16000248","DOIUrl":"https://doi.org/10.23880/vij-16000248","url":null,"abstract":"At a time when the COVID-19 pandemic is still at its peak with an expanding global activity, patients with HIV infection have always been a worrying population because, with a chronic disease causing immune system depletion, they are at high risk for serious diseases and poor prognosis. However, although there are no large studies directed at this population yet published both in terms of incidences and mortality that compare them with the non-HIV population.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"118 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129242905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Could UPR Manipulation Help to Tune the Inflammatory Response in the Course of COVID-19? UPR操作是否有助于调节COVID-19过程中的炎症反应?
Virology & Immunology Journal Pub Date : 2020-07-02 DOI: 10.23880/vij-16000244
Cirone M
{"title":"Could UPR Manipulation Help to Tune the Inflammatory Response in the Course of COVID-19?","authors":"Cirone M","doi":"10.23880/vij-16000244","DOIUrl":"https://doi.org/10.23880/vij-16000244","url":null,"abstract":"Highly pathogenic coronavirus SARS-CoV2, belonging to coronaviridae family, preferentially infects alveolar epithelial cells and immune cells resident or recruited in the lung, causing the disease known as COVID-19. As for other viruses, SARS-CoV2 is sensed by several PRRs, particularly TLR3 that triggers an intracellular signaling culminating in activation of transcription factors that promote the release of inflammatory and anti-viral cytokines, deeply shaping immune response. In a subgroup of patents, a massive release of inflammatory cytokines may also occur, strongly contributing to destroy alveolar cells, fibrosis and endothelial injury, thus favoring the activation of coagulation cascade. Viral infection also triggers UPR, an integrated response to stress, by activating the antiviral kinase PKR and by perturbing ER homeostasis. ER stress/UPR strongly contributes to the regulation of cytokine release also because its signaling intersects with PRR signaling at multiple levels. In this perspective we will discuss the possibility to tune the inflammatory/immune response to SARS-CoV2 infection by reducing ER stress, manipulating the different arms of UPR or inducing autophagy.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131448900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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