Virology & Immunology Journal最新文献

Immunological Challenges in Infants Living with HIV: A Review 感染艾滋病毒婴儿的免疫挑战：综述

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000340

Obeagu EI*

引用次数: 0

Origin and Evolution of SARS-CoV-2: An Enigma SARS-CoV-2 的起源和进化：一个谜团

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000338

Iqbal J

引用次数: 0

A Case of Dengue Meningitis Manifested as a Part of Expanded Dengue Syndrome 一例表现为登革热扩展综合征一部分的登革热脑膜炎病例

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000339

Gomes Rr

{"title":"A Case of Dengue Meningitis Manifested as a Part of Expanded Dengue Syndrome","authors":"Gomes Rr","doi":"10.23880/vij-16000339","DOIUrl":"https://doi.org/10.23880/vij-16000339","url":null,"abstract":"Dengue is a prevalent arthropod-borne viral disease in tropical and subtropical areas of the globe. Dengue clinical manifestations include asymptomatic infections; undifferentiated fever; dengue fever, which is characterized by fever, headache, retro orbital pain, myalgia, and arthralgia; and a severe form of the disease denominated dengue hemorrhagic fever/dengue shock syndrome, characterized by hemoconcentration, thrombocytopenia, and bleeding tendency. However, atypical manifestations, such as liver, central nervous system, and cardiac involvement, have been increasingly reported called expanded dengue syndrome. We report a 35 years old lady with atypical and rare presentation of dengue disease marked by meningitis. Condition improved after conservative treatment. Neurological complications in dengue are now increasingly observed with the most common case is aseptic meningitis. Dengue meningitis is self-limiting in almost all cases. Hepatic failure rarely dominates the clinical picture in adults. The main mechanism of dengue meningitis is still unknown though both direct viral infection and immune mediated damage have been suggested to be the cause. To avoid otherwise preventable morbidity and mortality, physicians should have a high index of suspicion for neurological complications in patients with dengue illness and should manage this accordingly","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"42 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139870612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Origin and Evolution of SARS-CoV-2: An Enigma SARS-CoV-2 的起源和进化：一个谜团

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000338

Iqbal J

引用次数: 0

Schedule Immunotherapy of Cancer; Current Status and Prospectus 癌症免疫疗法时间表；现状与展望

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000341

Khan Mn

{"title":"Schedule Immunotherapy of Cancer; Current Status and Prospectus","authors":"Khan Mn","doi":"10.23880/vij-16000341","DOIUrl":"https://doi.org/10.23880/vij-16000341","url":null,"abstract":"In the past decades, our knowledge about the relationship between cancer and the immune system has increased considerably. Immunotherapy has been a promising and rapidly evolving field in cancer treatment. However, keep in mind that the information might have advanced since then. Drugs like pembrolizumab and nivolumab, which target PD-1/PD-L1 pathways, have shown success in treating various cancers. These drugs release the brakes on the immune system, allowing it to better recognize and attack cancer cells. This involves harvesting and modifying a patient’s immune cells outside the body before infusing them back to target cancer cells. Researchers are exploring combinations of different immunotherapies and traditional treatments to enhance effectiveness and overcome resistance. Efforts to identify predictive biomarkers aim to personalize immunotherapy, ensuring it benefits patients who are most likely to respond. In summary, immunotherapy has made significant strides in cancer treatment, with ongoing research focusing on refining existing therapies, discovering new targets, and expanding the range of treatable cancers. The prospectus is promising, but addressing challenges remains critical for realizing the full potential of immunotherapy in the fight against cancer.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140462624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Dengue Meningitis Manifested as a Part of Expanded Dengue Syndrome 一例表现为登革热扩展综合征一部分的登革热脑膜炎病例

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000339

Gomes Rr

{"title":"A Case of Dengue Meningitis Manifested as a Part of Expanded Dengue Syndrome","authors":"Gomes Rr","doi":"10.23880/vij-16000339","DOIUrl":"https://doi.org/10.23880/vij-16000339","url":null,"abstract":"Dengue is a prevalent arthropod-borne viral disease in tropical and subtropical areas of the globe. Dengue clinical manifestations include asymptomatic infections; undifferentiated fever; dengue fever, which is characterized by fever, headache, retro orbital pain, myalgia, and arthralgia; and a severe form of the disease denominated dengue hemorrhagic fever/dengue shock syndrome, characterized by hemoconcentration, thrombocytopenia, and bleeding tendency. However, atypical manifestations, such as liver, central nervous system, and cardiac involvement, have been increasingly reported called expanded dengue syndrome. We report a 35 years old lady with atypical and rare presentation of dengue disease marked by meningitis. Condition improved after conservative treatment. Neurological complications in dengue are now increasingly observed with the most common case is aseptic meningitis. Dengue meningitis is self-limiting in almost all cases. Hepatic failure rarely dominates the clinical picture in adults. The main mechanism of dengue meningitis is still unknown though both direct viral infection and immune mediated damage have been suggested to be the cause. To avoid otherwise preventable morbidity and mortality, physicians should have a high index of suspicion for neurological complications in patients with dengue illness and should manage this accordingly","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"55 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139810896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severity and Situation of Asbestosis in the Era of COVID-19 Pandemic: A Systematic Review and Meta-Analysis COVID-19 大流行时期石棉沉滞症的严重程度和状况：系统回顾与元分析

Virology & Immunology Journal Pub Date : 2024-02-02 DOI: 10.23880/vij-16000342

Cheepsattayakorn A

{"title":"Severity and Situation of Asbestosis in the Era of COVID-19 Pandemic: A Systematic Review and Meta-Analysis","authors":"Cheepsattayakorn A","doi":"10.23880/vij-16000342","DOIUrl":"https://doi.org/10.23880/vij-16000342","url":null,"abstract":"A comprehensive search was carried out in mainstream bibliographic databases or Medical Subject Headings, including ScienDirect, PubMed, Scopus, and ISI Web of Science. The search was applied to the articles that were published between 2003 and early 2024. With strict literature search and screening processes, it yielded 3 articles from 64 articles of initial literature database. Asbestos, a heterogenous group of hydrated magnesium silicate minerals with a tendency of fiber separation. Asbestos-associated pleural fibrosis (pleural plaque or diffuse plural fibrosis), pleural thickening, or asbestosis are the majority of nonmalignant-asbestos-associated-disease conditions. Nevertheless, there is close association between of the nonmalignant-disease presence and the malignancy risk, particularly, lung cancer (complicated with pleural or peritoneal mesothelioma and cigarette smoking). One of search study clearly demonstrated rising trend of mortality in people aged 80 years and older among the three search studies, whereas COVID-19 pneumonia patients requiring respiratory support were higher among patients with history of asbestos exposure or asbestosis, compared to unexposed-asbestos patients (p = 0.015). In conclusion, The detection of an independent relation in small sample of subjects may be precluded by confounding covariables, such as smokers, having more comorbidity, more frequently male, and older age. In occupational asbestos exposure, respiratory support was required higher, compared to unexposed-asbestos patients. Proactive and cooperative participation can protect people with asbestos exposure from COVID-19 comorbidity.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"41 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140462255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Era of COVID-19 Pandemic Influencing on Global Tuberculosis Epidemic 影响全球结核病流行的 COVID-19 大流行时代

Virology & Immunology Journal Pub Date : 2023-11-08 DOI: 10.23880/vij-16000332

Cheepsattayakorn A

引用次数: 0

The Candida Genus Complex: Biology, Evolution, Pathogenicity Virulence and One Health Aspects, Beyond the Candida albicans Paradigm. A Comprehensive Review 念珠菌属复合体：生物学、进化、致病性、病毒性和健康方面》，《超越白色念珠菌范式》。全面综述

Virology & Immunology Journal Pub Date : 2023-11-08 DOI: 10.23880/vij-16000331

Leite-Jr Dp

{"title":"The Candida Genus Complex: Biology, Evolution, Pathogenicity Virulence and One Health Aspects, Beyond the Candida albicans Paradigm. A Comprehensive Review","authors":"Leite-Jr Dp","doi":"10.23880/vij-16000331","DOIUrl":"https://doi.org/10.23880/vij-16000331","url":null,"abstract":"Introduction: Yeast species of the genus Candida are important human pathogens and cause 90% of existing fungal infections. These pathogens within the One Health vision are closely linked to human, animal and environmental health. Objective: To emphasize the importance of the status of Candida yeasts, as infectious, opportunistic and emerging agents. Methodology: Databases and books relevant to the subject were used. Results: Candidemia is the most hostile fungal infection in the studied populations. Several cases of superficial and invasive diseases involve isolation of these yeasts in various population groups. Parenteral nutrition, administration of broad-spectrum antibiotics, prolonged hospitalization, chemotherapy and vascular catheters were considered risk factors. C. albicans is the most prevalent species, followed by C. parapsilosis, C. tropicalis and C. glabrata and more recently by the appearance of a new pathogen C. auris. Yeasts of the genus Candida are associated with a high lethality rate in relation to hematological malignancies, mainly C. albicans. Discussion: The pathogenic prevalence of Candida spp. is recognized all over the world. Candida albicans is the most commonly isolated species from clinical materials. The literature discusses methods used to differentiate strains in the study of the epidemiological relationship of members of the genus listed in this review. New Candida species isolated from clinical specimens continue to grow each year. Conclusion: Candidemia is a prevalent pathology with high incidence, morbidity and mortality in the world. The taxonomy, mechanisms of action and status of this yeast genus are related to its virulence, adhesion and epidemiological characteristics, more suitable for treatments to control cases of fungal infections caused by yeasts of the genus Candida.","PeriodicalId":334586,"journal":{"name":"Virology & Immunology Journal","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139283155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Science and the Potential Dangers behind RNA-based Vaccine Technology 基于 RNA 的疫苗技术背后的科学与潜在危险

Virology & Immunology Journal Pub Date : 2023-11-08 DOI: 10.23880/vij-16000333

Palacios-Castrillo R

引用次数: 0

Virology &amp; Immunology Journal最新文献

Virology & Immunology Journal最新文献