Schedule Immunotherapy of Cancer; Current Status and Prospectus

Khan Mn
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Abstract

In the past decades, our knowledge about the relationship between cancer and the immune system has increased considerably. Immunotherapy has been a promising and rapidly evolving field in cancer treatment. However, keep in mind that the information might have advanced since then. Drugs like pembrolizumab and nivolumab, which target PD-1/PD-L1 pathways, have shown success in treating various cancers. These drugs release the brakes on the immune system, allowing it to better recognize and attack cancer cells. This involves harvesting and modifying a patient’s immune cells outside the body before infusing them back to target cancer cells. Researchers are exploring combinations of different immunotherapies and traditional treatments to enhance effectiveness and overcome resistance. Efforts to identify predictive biomarkers aim to personalize immunotherapy, ensuring it benefits patients who are most likely to respond. In summary, immunotherapy has made significant strides in cancer treatment, with ongoing research focusing on refining existing therapies, discovering new targets, and expanding the range of treatable cancers. The prospectus is promising, but addressing challenges remains critical for realizing the full potential of immunotherapy in the fight against cancer.
癌症免疫疗法时间表;现状与展望
过去几十年来,我们对癌症与免疫系统之间关系的认识有了很大提高。免疫疗法一直是癌症治疗中前景广阔且发展迅速的领域。不过,请记住,自那时以来,信息可能已经有所进步。针对 PD-1/PD-L1 通路的药物,如 pembrolizumab 和 nivolumab,已在治疗各种癌症方面取得了成功。这些药物能解除免疫系统的 "刹车",使其更好地识别和攻击癌细胞。这涉及在体外采集和改造患者的免疫细胞,然后再将其回输到靶向癌细胞。研究人员正在探索将不同的免疫疗法与传统疗法相结合,以提高疗效并克服抗药性。确定预测性生物标志物的工作旨在实现免疫疗法的个性化,确保最有可能产生疗效的患者受益。总之,免疫疗法在癌症治疗方面取得了长足进步,目前的研究重点是完善现有疗法、发现新靶点和扩大可治疗癌症的范围。前景是光明的,但要充分发挥免疫疗法在抗击癌症方面的潜力,应对挑战仍然至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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