{"title":"CURRENT DIAGNOSING OF ASTHMA IN CHILDREN","authors":"O. Rechkina","doi":"10.31215/2306-4927-2021-29-4-40-43","DOIUrl":"https://doi.org/10.31215/2306-4927-2021-29-4-40-43","url":null,"abstract":"O. O. Rechkina Abstract Underdiagnosis and late diagnosis of asthma in children remain the topical problem of current world and local pediatrics, especially in primary medical care. Considering recent literature data, the author has presented the latest recommendations on timely diagnosis of asthma in children. The causes of underdiagnosis of the disease, terminology difficulties, risk of asthma progression development have been reviewed. Based on 2021 European Respiratory Society recommendations the key criteria of asthma diagnosis in children of different age have been listed. Key words: asthma in children, risk criteria, diagnosis","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"370 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123277347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. A. Poludenko, P. Antonenko, Y. Rozhkovskyi, K. Antonenko, K. Lobashova
{"title":"THE EFFECTIVENESS OF TREATMENT OF PULMONARY TUBERCULOSIS DEPENDING ON CYP3A4 GENOTYPE","authors":"H. A. Poludenko, P. Antonenko, Y. Rozhkovskyi, K. Antonenko, K. Lobashova","doi":"10.31215/2306-4927-2022-30-1-62-66","DOIUrl":"https://doi.org/10.31215/2306-4927-2022-30-1-62-66","url":null,"abstract":"Among the factors that can influence the course and effectiveness of the treatment of pulmonary tuberculosis (TB) the genetic characteristics of patients play an important role. It is established that cytochrome (CYP) 3A4/5 is involved in metabolism of more than 30 % of xenobiotics. Consequently, the activity of this enzyme is greatly influenced by responsible genes, such as CYP3А4. The aim of the study was the investigation of prognostic value of CYP3A4 polymorphism on the course and effectiveness of anti-tuberculosis therapy in patients with pulmonary TB. Materials and methods. Using PCR method, a detection of polymorphism of CYP3A4*1B, CYP3A4*1G genes, which determine the activity of CYP3A4 enzyme, was performed in 105 patients with newly diagnosed pulmonary TB. We have revied medical records at the beginning and at the end of inpatient treatment and considered the form, extent, regression rate of TB-lesions, and the rate of smear-positive cases. A statistical analysis of study data, expressed in absolute or relative values, was done using Pearson’s chi-squared test. Results: It was established that out of 105 enrolled TB-patients 84 individuals (80,0%) carried the genotype of “rapid metabolizers” (RA), the rest – 15 (14,3%) and 6 (5,7%) individuals were “intermediate metabolizers” (IM) and “slow metabolizers” (SM) correspondently. According to CYP3A4 genotype in patients with SM and IM the bi-lateral lesions as well as the processes of pulmonary destruction and dissemination, as well as smearpositiveness occurred more frequently than in RM. For example, in IM group the dissemination was observed almost two times more frequently than in RM (Р<0,05; χ2=4,44). At the end of the in-patient treatment in SM remaining TB-infiltrates observed more often, while the resolution of consolidation registered more rarely (66,7%) than in IM and RM (81,0% and 80,0%, correspondently). Also, in SM the TB infiltrates remained more often than in RM (33,3% versus 8,3%, Р<0,05; χ2=4,44). At the same time in IM the smear-positive status remained more often than in other groups. Conclusion. Genotypes of “intermediate metabolizers” and “slow metabolizers” according to CYP3A4 genes were associated with unfavorable pulmonary disease both at initiation and at the end of in-patient phase of the TB treatment. Identification of CYP3A4 genotype in pulmonary TB patients allows allocation of the groups of high risk of unfavorable TB course. Key words: pulmonary tuberculo","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127964916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Gavrysyuk, O. Bychenko, O. V. Strafun, N. Musienko, I. Liskina
{"title":"LUNG CARCINOMATOSIS: CLINICAL FEATURES AND RADIOLOGICAL SEMIOTICS","authors":"V. Gavrysyuk, O. Bychenko, O. V. Strafun, N. Musienko, I. Liskina","doi":"10.31215/2306-4927-2023-31-1-34-41","DOIUrl":"https://doi.org/10.31215/2306-4927-2023-31-1-34-41","url":null,"abstract":"The term “carcinomatosis” characterizes multiple metastases to serous membranes or organ parenchyma, caused by malignant tumor in patient’s body. Even though the name of this secondary neoplasia is derived from the name of malignant tumor originated from epithelial tissue — “carcinoma”, the term “carcinomatosis” is used to define a wide range of advanced metastases of malignant neoplasm of any origin. The main route of metastatic spread is hematogenous, less often — lymphatic, rare — aerogenous of through the diaphragm. According to autopsy data lung metastases are frequently found in chorionepithelioma, osteogenic sarcoma, kidney, testis, breast, and prostate cancer. In early hematogenous dissemination phase clinical signs are usually mild due to preliminary subpleural localization of metastases in lung. Only when visceral pleura, chest wall or bronchi are penetrated such symptoms as cough, chest pain, hemoptysis, dyspnea, and fever appear. Lymphangitic carcinomatosis is a secondary malignancy due to dissemination of tumor cells via the lymph vessels. In most cases the lymphangitic carcinomatosis is a result of primary hematogenous spread of metastases, appearing on radiograms or computed tomography scans as densities — nodules, mases or consolidation. In about 6–8 % of cases lymphangitic carcinomatosis are characterized by dissemination of tumor exclusively into lung interstitium without a distortion of lung parenchyma. This may cause a lot of difficulties for differential diagnosis. Despite the high diagnostic efficacy of bronchoscopy, video thoracoscopy and lung histology, the leading tool at initial stage of diagnostics is a high resolution computed tomography (CT). The article presents several clinical cases of lymphangitic carcinomatosis, observed at Interstitial lung diseases department of National Institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine. Key words: lung carcinomatosis, clinical features, differential diagnosis, computed tomography.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130318147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND CARDIOVASCULAR PATHOLOGY WITH FOCUS ON ARRHYTHMIAS","authors":"K. Dmytriiev, N. Slepchenko","doi":"10.31215/2306-4927-2022-30-2-31-36","DOIUrl":"https://doi.org/10.31215/2306-4927-2022-30-2-31-36","url":null,"abstract":"Chronic obstructive pulmonary disease is a third leading cause of death worldwide according to the WHO data. But often the direct mortality cause in these patients is cardiovascular complications, including arrhythmias. The aim of the study was to evaluate the concomitant cardiovascular pathology with focus on arrhythmia in patients with COPD. Materials and methods. 100 COPD patients were enrolled, mean age (64,09 ± 1,94) years, 66 male (66 %) and 34 female (34 %). There were 68 smokers (68 %), mean smoking duration — (24,44 ± 4,84) pack-years. Mean COPD duration — (9,35 ± 2,42) years. Source medical document data analysis regarding ongoing cardiovascular conditions was conducted. Results. Arterial hypertension was the most prevalent concomitant cardiovascular condition in COPD patients (77 %). Ischemic heart disease was the second by prevalence (67 %). Heart failure, as possible complication of pulmonary hypertension, cor pulmonale and/or cardiovascular conditions was found in 70 % of cases. Atrial fibrillation was observed in 18 % patients with COPD. Most patients suffered from atrial fibrillation with ventricular tachysystolia (14 %), which was quite typical for COPD due to hypoxia-related sympathetic nervous system activation. Conclusions. COPD and cardiovascular conditions have common pathogenetic mechanisms, leading to the occurrence of the mutual risks. COPD increases the risk of cardiovascular diseases progression and, conversely, presence of cardiovascular disease increases risk of COPD worsening. This connection creates a vicious circle of these diseases progression. Key words. COPD, cardiovascular diseases, arrhythmias.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122061277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PECULIARITIES OF CLINICAL MANAGEMENT OF ASTHMA DURING CORONAVIRUS DISEASE (COVID-19) PANDEMIC","authors":"L. Konopkina","doi":"10.31215/2306-4927-2021-29-4-44-47","DOIUrl":"https://doi.org/10.31215/2306-4927-2021-29-4-44-47","url":null,"abstract":"PECULIARITIES OF CLINICAL MANAGEMENT OF ASTHMA DURING CORONAVIRUS DISEASE (COVID-19) PANDEMIC L. I. Konopkina Abstract The review is dedicated to the problem of interrelations between asthma (A), COVID-19 and inhaled corticosteroid (ICS) therapy. According to Global Initiative for Asthma (GINA) long-term treatment with systemic corticosteroids may lead to significant immunosuppression. Potentially, this is associated with higher risk of incidence and severity of viral infections. That was the reason why WHO in the beginning of 2020 had not granted recommendation for using systemic corticosteroids in COVID-19 patients if not indicated for other causes (including A and COPD exacerbations, usually requiring short course of oral corticosteroids). In Spring 2021 GINA renewed its recommendations on COVID-19 in A patients considering the grade of A symptoms control. It was demonstrated that patients with well-controlled A (mild to moderate) were neither at higher risk of COVID-19 occurrence nor of its more severe course. The risk of death from COVID-19 was also not increased in patients with well-controlled A. Moreover, in A patients 50 years of age and older, regularly taking ICS and admitted to hospital due to COVID-19, the mortality rate was lower than in other hospitalized patients. Today, it is important to debate whether ICS may interfere with the possibility of getting infected by coronavirus. It is well known that budesonide is one of most often prescribed ICS molecule. Budesonide in vitro has demonstrated a potential antiviral effect against different types of SARS-CoV-2. There are several ongoing studies in vivo: NCT04416399 (Great Britain; completed), NCT04355637 (Spain), NCT04193878, NCT04377711 (USA), NCT04331470 (Iran), NCT04330 (South Korea). The results of STOIC study, organized and conducted by Oxford university scientists, are of special interest. It was demonstrated that outpatient use of budesonide in COVID-19 patients reduced the risk of hospitalization and emergency care utilization by 90 %. There was a statistically significant reduction in symptoms intensity and time to clinical cure. Interim results of PRINCIPLE study suggested that early treatment with inhaled budesonide shortetens recovery time by a median of three days (comparing with usual care). In Budesonide Turbohaler group 32 % patients reached sustain recovery within 14 days of randomization (comparing with 22 % of patients in usual care group). Conclusion. Despite interim character of presented clinical trials data in this review, use of inhaled budesonide in COVID-19 patients, from our point of view, may be considered in particular clinical cases after a obligatory discussion with the patient.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122209336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NEW PHENO-GENOTYPIC TECHNOLOGIES IN DIAGNOSIS OF TUBERCULOSIS","authors":"O. A. Zhurilo, A. Barbova, L. Sládková","doi":"10.31215/2306-4927-2022-30-1-35-46","DOIUrl":"https://doi.org/10.31215/2306-4927-2022-30-1-35-46","url":null,"abstract":"NEW PHENO-GENOTYPIC TECHNOLOGIES IN DIAGNOSIS OF TUBERCULOSIS O. A. Zhurilo, A. I. Barbova, L. M. Sladkova Abstract Widespread drug-resistant tuberculosis is a global problem and can have a negative impact on the global tuberculosis situation. Rapid diagnosis of the disease and early initiation of effective treatment based on the selection of personalized chemotherapy regimens are the basis for preventing the spread of tuberculosis. Microbiological methods which can justify the etiology of the process and determine the drug susceptibiliity of the pathogen are of particular importance for the diagnosis of tuberculosis. The review is focused on current methods of microbiological diagnosis of tuberculosis, including classical microbiological (diagnostic microscopy; solid and liquid media cultures) and modern molecular genetic tests (DNA strips; GeneXpert; multiplex PCR and other). The article presents data on modern methods of bacteriological and molecular genetic diagnosis of tuberculosis, their effectiveness and role in verifying the diagnosis of tuberculosis. The effectiveness of their integrated use to improve the quality of research and rapid detection of patients with M. tuberculosis has been proven. The place of the described methods in the diagnostic algorithm of tuberculosis laboratories is estimated. Further prospects for the diagnosis of tuberculosis associated with the use of new technologies are considered. The information on the current state of microbiological diagnostics of tuberculosis is generalized, the importance of development and introduction of the latest technologies in the diagnostic process is emphasized. Key words: tuberculosis, mycobacteria tuberculosis, drug resistance, methods of bacteriological diagnostics, molecular genetic technologies, PCR, sequencing.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"2012 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127373976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
І. А. Iliuk, I. V. Baranova, K. Postovitenko, S. Shevchuk, I. V. Kurilenko, N. Popenko
{"title":"APPLICATION OF THE OZONE THERAPY IN COMPLEX PROGRAM OF REHABILITATION OF PATIENTS WITH COMMUNITY-ACQUIRED POLYSEGMENTAL PNEUMONIA ASSOCIATED WITH SARS-COV-2 VIRUS (CLINICAL CASE)","authors":"І. А. Iliuk, I. V. Baranova, K. Postovitenko, S. Shevchuk, I. V. Kurilenko, N. Popenko","doi":"10.31215/2306-4927-2023-31-2-69-73","DOIUrl":"https://doi.org/10.31215/2306-4927-2023-31-2-69-73","url":null,"abstract":"For patients who survived a new coronavirus infection, rehabilitation measures are necessary to relieve the sequela of the disease. The article summarized literature data with a rationale and expected outcomes of ozone therapy in patients with post-COVID-19 syndrome. The presented clinical case demonstrates the effectiveness of intravenous ozone therapy as a part of rehabilitation program in patient with community-acquired polysegmental pneumonia associated with the SARS-CoV-2 virus. The use of this technique (combination of the infusion of ozonated saline and ozonated saline saturated with the patient’s blood) allows to reduce the activity of the inflammatory process, which contributes to the complete restoration of physical exercise tolerance and the improvement of the patient’s quality of life. Key words: COVID-19, pneumonia, rehabilitation, ozone therapy","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131602045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Opanasenko, L. Levanda, M. Shamrai, O. Tereshkovich, B. Konik, M. V. Bryansky, S. Bilokon
{"title":"CLINICAL CASE OF CHYLOTHORAX IN COMBINATION WITH HIV INFECTION","authors":"M. Opanasenko, L. Levanda, M. Shamrai, O. Tereshkovich, B. Konik, M. V. Bryansky, S. Bilokon","doi":"10.31215/2306-4927-2022-3-2-75-80","DOIUrl":"https://doi.org/10.31215/2306-4927-2022-3-2-75-80","url":null,"abstract":"Chylothorax is a pathological condition caused by obstruction or damage to the thoracic duct, which provides an outflow of lymph from the lower part of the body and gastrointestinal tract. The condition is manifested by the progressive accumulation of the chyle in the pleural cavity, which contains lymph of intestinal origin — milky, opalescent fluid, rich in lymphocytes, protein, triglycerides and chylomicrons. The most common symptom of chylothorax is shortness of breath, which usually occurs due to compression of the lungs by a significant accumulation of chyle. The diagnosis is established after removal of milkywhite fluid from the pleural cavity during thoracentesis. The peculiarity of chylothorax in AIDS patients suffering from malnutrition is that the fluid may not have the typical milky appearance due to poor absorption of oral fat and depletion of chylomicrons. The set of therapeutic measures for chylothorax in each case is individual. Treatment in all patients is aimed at stopping lymphorrhea in the pleural cavity and elimination of chylothorax. We presented a case where a combination of different treatment options was used, namely conservative therapy, videothoracoscopic parietal pleurectomy, thoracic duct ligation. Key words: chylothorax, HIV infection, pleural cavity","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124769294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SARCOIDOSIS: THE SILHOUETTES OF SCIENTIFIC AND PRACTICAL EVOLUTION","authors":"E. Khodosh","doi":"10.31215/2306-4927-2022-30-4-69-73","DOIUrl":"https://doi.org/10.31215/2306-4927-2022-30-4-69-73","url":null,"abstract":"Since the times of Jonathan Hatchinson, the author of first clinical description of sarcoidosis case, this disease was considered as dermatological one, slowly evolving into multisystem condition, associated with bone cyctosis, respiratory and other systems involvement. Later, due to epidemiology advances, it has become appreciated that sarcoidosis was spread globally, affecting people of all sexes and races. In the recent years, an achievements in different fields, especially biochemistry, genetics, immunology and molecular biology, significantly improved our understanding of this ilness. Each new methodological approach makes a solution of the enigma closer, particularly a still slipping away cause of the disease. The article reflects the major milestones of sarcoidosis history, highlighted by author. Key words: sarcoidosis, history, evolution of views.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116624477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"TRAUMATIC PNEUMONITIS DUE TO COMBAT CHEST INJURY AS A RISK FACTOR FOR PNEUMONIA","authors":"O. К. Yakovenkо","doi":"10.31215/2306-4927-2023-31-2-60-68","DOIUrl":"https://doi.org/10.31215/2306-4927-2023-31-2-60-68","url":null,"abstract":"The relevance of the problem of gunshot wounds and injuries as a result of the war with Russia continues to grow. Gunshot wounds and chest injury can cause several life-threatening conditions: bleeding, airway obstruction, tension pneumothorax with pericardial tamponade, open pneumothorax, massive hemothorax, chest dissection, tracheobronchial injury, diaphragm damage, myocardial injury, rupture thoracic aorta, esophageal damage and lung contusion. Lung contusion or traumatic pneumonitis is characterized by hemorrhage and swelling in the alveoli. This causes respiratory distress which develops 24 hours after lung injury, causing perfusion/ventilation mismatch by increasing pulmonary vascular resistance and decreasing lung compliance. From February 24, 2022 to February 18, 2023, in the Pulmonology Department of Volyn Regional Clinical Hospital, the rate of hospitalized military patients with chest injury due to mine-explosive wounds, shrapnel wounds, gunshot bullet wounds, and stub-cut wounds of the chest amounted to 19.3% of all pulmonary cases among military, admitted this year (n=88). Penetrating chest injury occurred in 41.1% of cases, nonpenetrating blunt chest injury (including behind armor blunt trauma) in 23.5 % of cases, chest trauma with soft tissue injury in 35.2 % of cases. Chest injury with fractured chest bones was detected in 47% of cases. In 52.9 % of cases, chest injuries and one stab-cut wound were on the side surface and chest, which was not protected by a bulletproof vest. Lung contusion or traumatic pneumonitis was observed in 70.5% of cases, including destruction in 29.4 %. Post-traumatic pneumonia was observed in 58.8 % of cases, that was caused by a non-hospital and hospital infection, pleurisy was observed in 17.6 % of cases. After chest injury, infiltrative-destructive pulmonary tuberculosis was detected in 5.8 % of cases and invasive pulmonary aspergillosis in 5.8 % of cases. Thus, the occurrence of a specific infection that can lead to destruction and aggravate destructive changes in the lung parenchyma should also be taken into account. Also, in 64.7 % of cases, metal, fragmentary, foreign bodies of the chest organs were found, and required further surgical removal. The article presents clinical cases of patients with chest injuries received as a result of military operations in Ukraine. Key words: traumatic pneumonitis, lung contusion, gunshot wound, chest injury, behind armor blunt trauma, pneumonia.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115465357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}