{"title":"结节病:科学与实践进化的剪影","authors":"E. Khodosh","doi":"10.31215/2306-4927-2022-30-4-69-73","DOIUrl":null,"url":null,"abstract":"Since the times of Jonathan Hatchinson, the author of first clinical description of sarcoidosis case, this disease was considered as dermatological one, slowly evolving into multisystem condition, associated with bone cyctosis, respiratory and other systems involvement. Later, due to epidemiology advances, it has become appreciated that sarcoidosis was spread globally, affecting people of all sexes and races. In the recent years, an achievements in different fields, especially biochemistry, genetics, immunology and molecular biology, significantly improved our understanding of this ilness. Each new methodological approach makes a solution of the enigma closer, particularly a still slipping away cause of the disease. The article reflects the major milestones of sarcoidosis history, highlighted by author. Key words: sarcoidosis, history, evolution of views.","PeriodicalId":328937,"journal":{"name":"Ukrainian Pulmonology Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SARCOIDOSIS: THE SILHOUETTES OF SCIENTIFIC AND PRACTICAL EVOLUTION\",\"authors\":\"E. Khodosh\",\"doi\":\"10.31215/2306-4927-2022-30-4-69-73\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Since the times of Jonathan Hatchinson, the author of first clinical description of sarcoidosis case, this disease was considered as dermatological one, slowly evolving into multisystem condition, associated with bone cyctosis, respiratory and other systems involvement. Later, due to epidemiology advances, it has become appreciated that sarcoidosis was spread globally, affecting people of all sexes and races. In the recent years, an achievements in different fields, especially biochemistry, genetics, immunology and molecular biology, significantly improved our understanding of this ilness. Each new methodological approach makes a solution of the enigma closer, particularly a still slipping away cause of the disease. The article reflects the major milestones of sarcoidosis history, highlighted by author. Key words: sarcoidosis, history, evolution of views.\",\"PeriodicalId\":328937,\"journal\":{\"name\":\"Ukrainian Pulmonology Journal\",\"volume\":\"7 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ukrainian Pulmonology Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31215/2306-4927-2022-30-4-69-73\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ukrainian Pulmonology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31215/2306-4927-2022-30-4-69-73","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SARCOIDOSIS: THE SILHOUETTES OF SCIENTIFIC AND PRACTICAL EVOLUTION
Since the times of Jonathan Hatchinson, the author of first clinical description of sarcoidosis case, this disease was considered as dermatological one, slowly evolving into multisystem condition, associated with bone cyctosis, respiratory and other systems involvement. Later, due to epidemiology advances, it has become appreciated that sarcoidosis was spread globally, affecting people of all sexes and races. In the recent years, an achievements in different fields, especially biochemistry, genetics, immunology and molecular biology, significantly improved our understanding of this ilness. Each new methodological approach makes a solution of the enigma closer, particularly a still slipping away cause of the disease. The article reflects the major milestones of sarcoidosis history, highlighted by author. Key words: sarcoidosis, history, evolution of views.