Aging Medicine最新文献

{"title":"Improving Post-Fall Assessment Documentation in Older Inpatients Using a Structured Falls Proforma: A Retrospective Cohort Study.","authors":"Ella V Brockwell-Mole, Dujinthan Jayabalan, Su Kitchen, Minoti Bhagat","doi":"10.1002/agm2.70113","DOIUrl":"https://doi.org/10.1002/agm2.70113","url":null,"abstract":"<p><strong>Objective: </strong>Falls among hospital inpatients are a major cause of morbidity, mortality, and healthcare burden. The aim of this study was to evaluate the association between the use of a structured Falls Proforma and the completeness of post-fall assessment documentation in an Australian hospital.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on patients who experienced inpatient falls between January 2022 and December 2024. Fall events were stratified by 6-month audit intervals, and cases were randomly selected within each stratum using computer-generated sampling. All falls within this time frame were eligible for inclusion; only a patient's first fall among those aged > 65 years was counted, and data with missing details were excluded from analysis. Falls were categorized into \"proforma\" or \"non-proforma\" groups. Documentation across 12 assessment domains was compared, and demographic and clinical characteristics associated with proforma use were evaluated.</p><p><strong>Results: </strong>A stratified random sample of 202 inpatient falls was reviewed, with 167 eligible for analysis. Of these, 125 (75%) were assessed using the proforma. Documentation was significantly higher in the proforma group across examination domains: cervical spine (96.8% vs. 47.6%), hip (98.4% vs. 40.5%), cranial nerve (92.8% vs. 40.5%), upper limb neurology (93.6% vs. 45.2%), lower limb neurology (95.2% vs. 42.9%), external head (97.6% vs. 35.7%), cognition (95.2% vs. 19.0%), coagulopathy (98.4% vs. 16.7%), musculoskeletal (95.2% vs. 35.7%), mobility (92.0% vs. 7.1%), and contributing factors (87.2% vs. 59.5%) (all <i>p</i> < 0.001). Scenario documentation was high in both groups (85.6% vs. 95.2%, <i>p</i> = 0.100). In multivariable analysis, preexisting cognitive impairment was associated with lower odds of proforma use, however this association did not reach statistical significance after adjustment (OR = 0.450, 95% CI 0.190-1.030<i>, p</i> = 0.062).</p><p><strong>Conclusions: </strong>Use of a structured Falls Proforma was associated with significantly greater completeness of post-fall documentation. However, lower uptake among patients with cognitive impairment may represent a disparity in documentation within a high-risk population. Embedding structured tools into routine practice may standardize documentation and support adherence to recommended post fall assessment frameworks.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13662889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronotype and Peripheral Clock Genes: Association With Frailty and Insomnia in Mexican Older Adults.","authors":"Citlally E Ortiz-Vázquez, Paola Garcia-delaTorre, Sergio Sánchez-García, Lorena Aguilar-Arnal, Lucía Mendoza-Viveros","doi":"10.1002/agm2.70117","DOIUrl":"https://doi.org/10.1002/agm2.70117","url":null,"abstract":"<p><strong>Objectives: </strong>Frailty is a geriatric syndrome associated with increased vulnerability to adverse health outcomes in older adults. Circadian rhythms regulate multiple physiological processes relevant to aging, including sleep, metabolism, and immune function; however, the relationship between circadian biology and frailty remains incompletely understood. This study aimed to examine associations between chronotype, insomnia, metabolic parameters, and peripheral clock gene expression in Mexican older adults.</p><p><strong>Methods: </strong>A total of 751 community-dwelling older adults were included. Chronotype was assessed using the Morningness-Eveningness Questionnaire (MEQ), and associations with insomnia and metabolic parameters were evaluated using multivariate regression models. Peripheral circadian clock gene expression was analyzed in peripheral blood mononuclear cells (PBMCs) from a subsample of 82 participants using principal component analysis (PCA) and gene-specific linear regression models.</p><p><strong>Results: </strong>Most participants exhibited a morning chronotype. Individuals with an extreme morning chronotype had lower odds of insomnia than those with an intermediate chronotype (adjusted <i>OR</i> = 0.393, 95% <i>CI</i> 0.169-0.827, <i>p</i> = 0.020). No significant associations between chronotype and metabolic parameters remained after adjustment for covariates and correction for multiple comparisons. PCA identified a coordinated pattern of clock gene expression, with pre-frail and frail participants exhibiting lower PC1 scores than robust individuals. Gene-specific analyses showed lower expression of several clock genes in pre-frail and frail participants, while lower CLOCK expression remained significantly associated with pre-frailty after adjustment for chronotype, insomnia, age, sex, and body mass index.</p><p><strong>Conclusions: </strong>In this cohort of older adults, morning chronotype was associated with lower odds of insomnia, whereas frailty was associated with differences in peripheral clock gene expression measured at a morning time point. These findings support a relationship between circadian-related characteristics and frailty in older adults and warrant further investigation using longitudinal and multi-time-point circadian assessments.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13662892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Radiologic Service Utilization and Imaging Expenditure in Supercentenarians in Colombia.","authors":"Gabriela Puentes, Oscar Espinosa, Valeria Bejarano, Angela Guarnizo","doi":"10.1002/agm2.70114","DOIUrl":"https://doi.org/10.1002/agm2.70114","url":null,"abstract":"<p><p>We analyzed radiologic service utilization among Colombian supercentenarians (2014-2023) using administrative health data. Imaging use averaged 3.03 examinations per person annually. General radiology, ultrasound, and computed tomography were the most frequently used modalities. Mean per capita imaging expenditure was 185.22 PPP USD. Compared with centenarians, supercentenarians exhibited a more restricted pattern of imaging utilization, characterized by lower use of advanced imaging modalities and the absence of interventional radiology procedures. These findings indicate a distinct pattern of radiologic service use at extreme ages.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13658884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Hemodynamic Changes in Older Adults With Cognitive Complaints According to the Presence of Peripheral Artery Disease.","authors":"SangMi Noh, Hae-Eun Shin, YongSoo Shim","doi":"10.1002/agm2.70121","DOIUrl":"https://doi.org/10.1002/agm2.70121","url":null,"abstract":"<p><strong>Objective: </strong>As a systemic expression of atherosclerosis, peripheral artery disease (PAD) has the potential to alter cerebral hemodynamics in elderly individuals presenting with cognitive concerns. However, how PAD status shapes the longitudinal trajectory of cerebral hemodynamics has not been well characterized.</p><p><strong>Methods: </strong>We conducted a single-center longitudinal observational study enrolling 132 participants (21 controls, 39 mild cognitive impairment, 72 mild Alzheimer's disease). All participants underwent transcranial Doppler (TCD) ultrasonography, ankle-brachial index (ABI) measurement, brain MRI, and cognitive assessments at baseline and follow-up (~13.45 months). PAD was defined as ABI < 0.90. Bilateral mean flow velocity (MFV), pulsatility index (PI), and resistance index (RI) of the middle cerebral artery (MCA) were tracked longitudinally across both time points.</p><p><strong>Results: </strong>PAD was identified in 13 participants (9.8%). Baseline TCD parameters, vascular risk factors, white matter lesions on brain MRI, and cognitive measures were comparable between groups. At follow-up, the PAD group showed significantly higher MCA MFV after age adjustment (left <i>p</i> < 0.001; right <i>p</i> = 0.005). MFV increased in the PAD group (left +16.45 cm/s) but decreased in the non-PAD group (left -3.37 cm/s), with a significant between-group difference. PI and RI did not change in either group. Cognitive and functional outcomes were similar across groups throughout the study.</p><p><strong>Conclusion: </strong>These findings identify PAD as a condition associated with progressive MCA MFV elevation in the context of preserved cognition, implying that subclinical cerebrovascular changes are detectable by TCD before overt clinical worsening. Future research involving larger cohorts and extended follow-up is required to determine whether such hemodynamic changes forecast eventual cognitive deterioration.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging Barangay Health Workers to Strengthen Geriatric Care in an Aging Philippines.","authors":"Darin Jan C Tindowen","doi":"10.1002/agm2.70115","DOIUrl":"https://doi.org/10.1002/agm2.70115","url":null,"abstract":"<p><p>Population aging in the Philippines requires innovative, community-based approaches to strengthen geriatric care delivery. This article highlights the potential of Barangay Health Workers as frontline partners in promoting healthy aging through early detection, chronic disease monitoring, and coordinated referral services. Expanding BHW roles through standardized training and policy support can address gaps in geriatric healthcare access. A strengthened community health workforce can contribute to an age-responsive and sustainable Philippine healthcare system.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13653639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Geriatric Hospice Care in China: An Interpretation and Critical Analysis of the New National Standard WS/T 844–2024","authors":"Yinan Wu,&nbsp;Chang Li,&nbsp;Shangxin Liu,&nbsp;Huiping Chen,&nbsp;Yongyi Chen,&nbsp;Xinyu Chen,&nbsp;Yumei Wang,&nbsp;Yuan Qin,&nbsp;Zhong Yi,&nbsp;Pengjun Zhang,&nbsp;Biyan Jiang,&nbsp;Jianye Wang,&nbsp;Bei Lai","doi":"10.1002/agm2.70097","DOIUrl":"10.1002/agm2.70097","url":null,"abstract":"<p>China's demographic landscape is undergoing a dramatic transformation. With over 297 million people aged 60 and above—comprising 21.1% of the total population—the nation faces unprecedented challenges in providing adequate end-of-life care for its elderly citizens. It is against this backdrop that the National Health Commission of the People's Republic of China released the “Standard for Geriatric Hospice Care Wards (WS/T844–2024)” on July 24, 2024, which aims to fill the institutional gap and promote the critical transition of hospice care services from “empirical exploration” to “standardized development”. This Standard specifies the configuration requirements for geriatric hospice care wards in terms of ward configuration, staffing models, age-appropriate equipment, and quality assurance mechanisms. While the WS/T 844–2024 standard establishes a much-needed framework for service standardization, its ultimate outcome will depend on how well it can be adapted to China's diverse healthcare landscape and resource constraints. This critique aims to identify both the strengths and potential limitations of the WS/T 844–2024 standard, offering insights for policymakers and healthcare providers tasked with its implementation. By doing so, the article addresses the following questions: What blueprint does the WS/T 844–2024 standard outline for geriatric hospice care in China? What key tensions may arise when this blueprint confronts the practical challenges of China's uneven distribution of medical resources, shortage of professional workforce, and cultural traditions? And how can a pragmatic implementation pathway be constructed to bridge the gap between the ideal and the reality?</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"9 4","pages":"438-442"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13488477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Consensus on Influenza Vaccine and Pneumococcal Vaccination in Elderly People With Chronic Respiratory Diseases (2024)","authors":"Lijing Wang,&nbsp;Qiao Yu,&nbsp;Qiong Chen,&nbsp;Pulin Yu,&nbsp;Expert Committee of Consensus Opinion on Influenza Vaccine and Pneumococcal Vaccine Vaccination for Elderly People with Chronic Respiratory Diseases, Respiratory Group of Chinese Geriatrics Society","doi":"10.1002/agm2.70090","DOIUrl":"10.1002/agm2.70090","url":null,"abstract":"<p>Chronic respiratory diseases pose a serious threat to the health of the population due to their high incidence, high disability rate, and poor prognosis. It is necessary to improve the prevention and treatment status of chronic respiratory diseases. Vaccination against influenza and pneumococcal infections can reduce the risk of respiratory infections, lower hospitalization and mortality rates, and alleviate disease burden in individuals with chronic respiratory diseases. However, insufficient public awareness of influenza and pneumococcal vaccines and the lack of recommendation by medical personnel have led to the low actual vaccination rate of influenza and pneumococcal vaccines in elderly people with chronic respiratory diseases in China. Based on existing research evidence both domestically and internationally, this consensus describes the burden of influenza and pneumococcal diseases in elderly people with chronic respiratory diseases, the protective effect and safety of influenza and pneumococcal vaccines, and vaccination recommendations, aiming to promote the vaccination rate of elderly people with chronic respiratory diseases, better play the role of vaccines in preventing influenza and pneumococcal diseases, and reduce the occurrence of respiratory infections and related serious complications in the population with chronic respiratory diseases.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"9 4","pages":"343-354"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Consensus on the Management of Obesity in Older Adults (2026 Edition)","authors":"Qi Pan,&nbsp;Lixin Guo","doi":"10.1002/agm2.70105","DOIUrl":"10.1002/agm2.70105","url":null,"abstract":"<p>Obesity in older adults has become a prominent public health issue. Owing to age-related physiological changes and multimorbidity, obesity in this population is associated with complex clinical manifestations and markedly increased difficulty in management. Based on this, a multidisciplinary panel of obesity experts from Beijing Hospital, National Center for Gerontology, formulated this consensus after rigorous evaluation and iterative revision. The consensus emphasizes that management of obesity in older adults requires comprehensive assessment according to age and overall health status and should adopt a patient-centered, individualized, and stratified strategy. By adhering to the principles of safety first, functional improvement, and steady progress, the goals are to reduce visceral fat accumulation, maintain or increase muscle mass, protect bone health, and improve physical function and overall health. Special attention should be paid to sarcopenia in older adults. Adequate intake of high-quality protein, combined with an individualized resistance exercise program, is an effective strategy for maintaining muscle mass. Selection of weight-loss medication should be guided by evidence supporting its benefit for obesity-related complications or comorbidities, with close monitoring of adverse reactions.</p>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"9 4","pages":"355-369"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535939/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148881691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation and Ranking for Scientific, Transparent and Applicable of Chinese Geriatrics Guidelines and Consensus Published in 2023","authors":"Daiping Li,&nbsp;Chao Gao,&nbsp;Xiaoli Huang,&nbsp;Ling Kang,&nbsp;Birong Dong,&nbsp;Jirong Yue,&nbsp;the Specialized Committee for Geriatric Medicine of the STAR","doi":"10.1002/agm2.70100","DOIUrl":"10.1002/agm2.70100","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aims to evaluate the Scientific, Transparent, and Applicable Rankings (STAR) of guidelines and consensus published in Chinese geriatric medicine journals in 2023.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The working group conducted a systematic search in eight major Chinese and English databases for guidelines and consensuses published by Chinese scholars in the field of geriatric medicine in 2023. The selected guidelines and consensuses were rated using the STAR rating tool, and the rating results were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 10 guidelines and 20 expert consensus documents were included. The STAR scores ranged from 9.4 to 55.7 with a mean of 29.3 ± 11.2. The STAR scores of 10 guidelines ranged from 16.1 and 55.7 with an average of 35.5 ± 13.1. The STAR scores of 20 consensus ranged from 9.4 and 48.5 with an average of 26.2 ± 8.9.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Guidelines and consensus in geriatric medicine have shown significant improvements in 2023 compared to 2022 across registration, consensus methodology, working groups, and accessibility. However, areas such as protocol development, funding, and clinical issues require further refinement by the authors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"9 4","pages":"406-415"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13463843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148727054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons","authors":"Ali Vahedi,&nbsp;Maria Eriksdotter,&nbsp;Hege Ihle-Hansen,&nbsp;Torgeir Bruun Wyller,&nbsp;Anne Rita Øksengård,&nbsp;Brynjar Fure","doi":"10.1002/agm2.70104","DOIUrl":"10.1002/agm2.70104","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Older persons are often referred to emergency departments due to acute functional decline, that is, reduced activities of daily living occurring in the days before hospitalization, frequently driven by acute medical conditions. We aimed to describe frailty in the oldest hospitalized patients presenting with acute functional decline and evaluate predictors of death, severe frailty and nursing home admission after 3–6 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We included 119 persons with acute functional decline, aged ≥ 80 years, ≥ 5 systemic diagnoses, ≥ 5 drugs daily, from an acute geriatric ward and reassessed after 3–6 months. All were evaluated with comprehensive geriatric assessment. Severe frailty was defined as Clinical Frailty Scale 7–8.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-one (34.4%) were free from severe frailty at baseline and 32 (48.5%) at follow-up. Male sex (adjusted OR 11.820, 95% confidence interval [CI] 3.670–38.120), Clinical Dementia Rating (CDR) ≥ 0.5 (adjusted OR 3.920, 95% CI 1.020–15.100), severe frailty at baseline (adjusted OR 6.930, 95% CI 1.830–26.210), type 2 diabetes (adjusted OR 7.460, 95% CI 2.040–27.250), and cancer (adjusted OR 5.640, 95% CI 1.040–30.690) were associated with death at follow-up. Hearing impairment (adjusted OR 7.060, 95% CI 1.430–34.760), CDR ≥ 0.5 (adjusted OR 5.390, 95% CI 1.260–23.070), and nursing home living before admission (adjusted OR 4.260, 95% CI 1.010–17.920) were associated with severe frailty at follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Many persons with acute functional decline have severe frailty. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living seem to increase the risk of severe frailty or death and should be considered when person-centered care is planned for hospitalized older people.</p>\u0000 </section>\u0000 </div>","PeriodicalId":32862,"journal":{"name":"Aging Medicine","volume":"9 4","pages":"374-383"},"PeriodicalIF":3.1,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13491115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}