Heart Views最新文献

{"title":"Early Intervention in Asymptomatic Patients with Severe Aortic Stenosis.","authors":"Rasha Kaddoura, Mohammed Al-Hijji","doi":"10.4103/heartviews.heartviews_7_25","DOIUrl":"10.4103/heartviews.heartviews_7_25","url":null,"abstract":"","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"69-70"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruptured Membranous Interventricular Septal Aneurysm Causing Left Ventricular Outflow Obstruction in Congenitally Corrected Transposition of Great Arteries.","authors":"Neeraj Kumar, Niraj Nirmal Pandey, Sivasubramanian Ramakrishnan, Priya Jagia","doi":"10.4103/heartviews.heartviews_3_25","DOIUrl":"10.4103/heartviews.heartviews_3_25","url":null,"abstract":"","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"67-68"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Milestone in Cardiac Care in Iraq: One-year Follow-up after the Nation's First Continuous-flow Left Ventricular Assist Device Implantation, Paving the Way for Heart Transplantation.","authors":"Ali Saad Merzah, Jasmin Hanke, Günes Dogan, Salwan Qahtan, Saleh Mehdi Al-Hasnawi, Lukman Faily, Arjang Ruhparwar, Jan D Schmitto","doi":"10.4103/heartviews.heartviews_20_25","DOIUrl":"10.4103/heartviews.heartviews_20_25","url":null,"abstract":"<p><p>The first successful implantation of the HeartMate 3 LVAD in Iraq represents a transformative achievement in the nation's medical history. Conducted collaboratively by German and Iraqi teams in December 2023, the procedure addressed end-stage heart failure in a 60-year-old male. Despite significant healthcare challenges, the patient's functional status improved markedly, moving from New York Heart Association Class IV to Class I within a year. This groundbreaking case highlights the potential for Iraq to integrate advanced cardiac interventions into its healthcare system, paving the way for heart transplantation programs. Ongoing collaboration and investment in healthcare infrastructure will be pivotal for sustaining these innovations.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"58-61"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arrhythmogenic Cardiomyopathy with Biventricular Involvement and Right Ventricular Thrombosis: A Multi-modality Imaging Approach.","authors":"Fawaz Bardooli, Dhuha Rashed Aljawder, Dileep Kumar, Sadananda Padavagodu Shivappa, Anna Baritussio","doi":"10.4103/heartviews.heartviews_145_24","DOIUrl":"10.4103/heartviews.heartviews_145_24","url":null,"abstract":"<p><p>Arrhythmogenic cardiomyopathy (AC) is an inherited heart disease characterized by fibro-fatty changes of either ventricles in isolation or in combination. AC may present with ventricular tachycardia (VT), usually with a left bundle branch block (LBBB) morphology (although VT with right bundle branch block morphology may also be encountered). Diagnosis is multi-parametric and cardiovascular magnetic resonance (CMR) holds a key role in showing the typical tissue abnormalities of the ventricles. We report the case of a patient presenting with LBBB VT with multi-modality imaging findings consistent with AC with biventricular involvement and right ventricular (RV) thrombosis. The patient was treated with antiarrhythmics, heart failure therapy, and implantable cardioverter-defibrillator implantation. RV thrombus was treated with new oral anticoagulants.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"48-53"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Kissing Balloon Inflation Technique for Coronary Protection during Transcatheter Aortic Valve Replacement.","authors":"Omar Aldalati, Mohammad Alkhalil, Mardi Hamra, Azfar Zaman, Richard Anderson","doi":"10.4103/heartviews.heartviews_141_23","DOIUrl":"10.4103/heartviews.heartviews_141_23","url":null,"abstract":"<p><p>Transcatheter aortic valve replacement (TAVR) using the valve-in-valve (ViV) approach presents a substantial risk of coronary artery obstruction, which adversely impacts patient outcomes. In this report, we describe the utilization of the simultaneous kissing balloon inflation technique during ViV TAVR, which resulted in significant improvement in the patient's condition.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"54-57"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-hospital Utilization and Dose Optimization of Guideline-Directed Medical Therapies among Acute Heart Failure Yemeni Patients.","authors":"Adnan Al-Radhi, Abdulkafi Shujaa, Nora Alsagheer, Taha Al-Maimoony, Ahmed Al-Motarreb","doi":"10.4103/heartviews.heartviews_152_24","DOIUrl":"10.4103/heartviews.heartviews_152_24","url":null,"abstract":"<p><strong>Background: </strong>Despite robust evidence and strong recommendations supporting the incremental and dose-related benefit of combined neurohormonal blockers (guideline-directed medical therapy [GDMT]) in heart failure with reduced ejection fraction (HFrEF), real-world data shows significant gaps in uses and/or dosing of these therapies.</p><p><strong>Rationale: </strong>As heart failure (HF) hospitalization is viewed as an opportunity for the initiation and optimization of HF life-saving medications and the paucity of data exploring this important issue in Yemen, the current study aims to fill this gap.</p><p><strong>Objective: </strong>The objective of this study was to evaluate the use, number, and dose optimization of the GDMT in a cohort of hospitalized patients with HFrEF in Yemen.</p><p><strong>Materials and methods: </strong>We included 1408 Yemeni patients with available ejection fraction (EF) enrolled in the Gulf CARE registry from February to November 2012. In this analysis, we included only four classes of GDMT, renin-angiotensin system inhibitors (RASi), evidence-based beta-blockers, and mineralocorticoid receptor antagonist (MRA). Each drug dose was converted to the equivalent daily dose of a selected representative drug. We explored the prescription of these drugs either separately or in combination and the target dose (TD) achievement for each drug at admission and discharge.</p><p><strong>Results: </strong>Among the1408 patients recruited, 916 patients (65%) were males and mean age was 53.5 ± 15.4 years, 53% (n = 748) presented with HFrEF (EF < 40%), 21% (n = 299) with HFpEF (EF ≥ 50%), and 26% (n = 361) with HFmrEF (Heart failure with mildly reduced ejection fraction) (EF 40-49%). Beta-blockers, renin-angiotensin system inhibitors, and MRA were prescribed to 28% (<i>n</i> = 400), 51% (<i>n</i> = 716), and 10% (<i>n</i> = 143) at baseline and 69.5% (<i>n</i> = 978), 82% (<i>n</i> = 1157), and 59% (<i>n</i> = 831) on discharge, respectively. The rate of TD achievement was (0.0% vs. 3.6% (<i>n</i> = 35]) for beta-blockers and (0.279% [<i>n</i> = 2] vs. 1.5% [<i>n</i> = 17]) for renin-angiotensin system inhibitors on baseline and discharge, respectively. Among 748 patients with HFrEF, 36% (<i>n</i> = 270) were not receiving any GDMT at baseline, while triple therapy was prescribed to 10% (<i>n</i> = 74) at baseline and 61.5% (<i>n</i> = 460) on discharge.</p><p><strong>Conclusions: </strong>A substantial gap in GDMT implementations with both underutilization and low TD achievement in patients with HFrEF in Yemen.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"7-18"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Utilization of Lipoprotein (a) and its Relationship with Cardiovascular Outcomes: A Retrospective Cohort Study from a Public Hospital in New York City.","authors":"Maisha Maliha, Natalia Nazarenko, Sanjana Nagraj, Vikyath Satish, Amrin Kharawala, Pawel Borkowski, Vibhor Garg, Tinatin Saralidze, Dimitrios Karamanis, Leonidas Palaiodimos","doi":"10.4103/heartviews.heartviews_138_24","DOIUrl":"10.4103/heartviews.heartviews_138_24","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Lipoprotein (a) [Lp(a)] is an independent genetic risk factor for atherosclerotic cardiovascular disease (ASCVD) and is associated with an increased risk of heart failure (HF), multiple vascular and valvular abnormalities and is closely linked to various lipid components, particularly low-density lipoprotein (LDL) cholesterol. Despite its clinical significance, Lp(a) testing has not gained widespread use in healthcare practice. Our study aimed to assess the utilization of Lp(a) testing and its association with ASCVD risk factors, HF phenotypes, vascular and valvular pathologies, lipid profiles, and the use of lipid-lowering drugs at a safety-net hospital within the largest municipal healthcare system in the United States.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We conducted a retrospective study at Jacobi Medical Center, a public hospital in the Bronx, New York. Using a cutoff value of 75 nmol/L, we compared a study group with elevated Lp(a) levels to a control group. The primary outcomes assessed were the association between Lp(a) levels and ASCVD risk factors, HF phenotypes (classified by left ventricular ejection fraction), and vascular and valvular pathologies. Secondary outcomes included the relationship between elevated Lp(a) levels and lipid profiles, as well as the use of lipid-lowering medications such as statins, proprotein convertase subtilisin/kexin type 9 inhibitors, and ezetimibe.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study included 78 patients (41.0% female, median age 52.0 years, interquartile range 44.0-66.0 years). Patients with elevated Lp(a) had a significantly higher incidence of HF with preserved ejection fraction (HFpEF) (18.8% vs. 0%, &lt;i&gt;P&lt;/i&gt; = 0.004), but there was no significant association with HF with reduced ejection fraction (15.6% vs. 36.3%, &lt;i&gt;P&lt;/i&gt; = 0.613) or HF with midrange ejection fraction (12.5% vs. 13.6%, &lt;i&gt;P&lt;/i&gt; = 0.061). No significant associations were found between elevated Lp(a) and ASCVD risk factors, or valvular and vascular pathologies. However, patients with high Lp(a) levels had significantly higher LDL levels (96.5 mg/dL vs. 73.0 mg/dL, &lt;i&gt;P&lt;/i&gt; = 0.04). There was no significant association between the use of lipid-lowering drugs and elevated Lp(a) levels. Notably, some patients exhibited unexpectedly high Lp(a) levels despite having a comparable demographic and comorbidity risk profile to those with normal Lp(a) levels.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Patients with elevated Lp(a) levels were more likely to present with HFpEF and elevated LDL levels, although no significant associations were found with ASCVD risk factors, vascular, or valvular pathologies. The unexpectedly high Lp(a) levels in some individuals with similar risk profiles suggest the need for further research to refine guidelines for Lp(a) testing. Our study also highlighted the underutilization of Lp(a) testing in clinical practice, underscoring the importance of increasing awareness and improving ASCV","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"19-27"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of Microalbuminuria with Ischemic Heart Disease in Nondiabetic Subjects.","authors":"Ankit Jain, Vikas Kumar, Kunal Shrimal","doi":"10.4103/heartviews.heartviews_114_23","DOIUrl":"10.4103/heartviews.heartviews_114_23","url":null,"abstract":"<p><strong>Background: </strong>Microalbuminuria has been established as a marker for increased cardiovascular risk in diabetic patients. Nonetheless, its correlation with ischemic heart disease (IHD) among individuals without diabetes has received limited attention. The current study was performed to explore the potential link between microalbuminuria and IHD in nondiabetic subjects.</p><p><strong>Methodology: </strong>During 2 years, a case-control study was executed, encompassing 100 individuals without diabetes who had IHD as cases, and an equal number of 100 non-IHD controls. Microalbuminuria levels were evaluated alongside diverse cardiovascular risk factors in both sets. IBM-SPSS version 25.0 was used for statistical analysis.</p><p><strong>Results: </strong>The mean age, gender distribution, and body mass index were similar between the cases and controls. There was a higher prevalence of smokers and alcohol users among the cases compared to controls. In addition, a positive family history of IHD was more prevalent in the case group. In the case group, the mean values of systolic blood pressure, diastolic blood pressure, mean arterial pressure, fasting blood glucose, cholesterol, low-density lipoprotein (LDL), serum creatinine, and urine albumin levels were notably elevated compared to the control group. A significant increase in microalbuminuria levels in the case group was observed.</p><p><strong>Conclusion: </strong>The results reveal a substantial link between microalbuminuria and IHD in individuals without diabetes. Microalbuminuria was independently correlated with major cardiovascular risk factors, including alcohol and cigarette use, and higher levels of cholesterol, LDL, and serum creatinine. These findings suggest that urine albumin measurements could serve as an early marker for identifying cardiovascular disease risk factors and potentially aid in preventive interventions in the general population.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"28-33"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Implantation for Severe Aortic Insufficiency Due to Infective Endocarditis in a Patient with Cirrhosis and Hepatocellular Cancer: A Novel Indication.","authors":"Salem Abujalala, Huseyin Ede, Waleed Khalid Abdullatef, Mohammed Ahmad Al-Hijji","doi":"10.4103/heartviews.heartviews_139_23","DOIUrl":"10.4103/heartviews.heartviews_139_23","url":null,"abstract":"<p><p>Infective endocarditis (IE) of the native aortic valve (AV) secondary to <i>Streptococcus infantarius</i> is subacute, a highly destructive pathology leading to aortic regurgitation (AR) and severe cardiac complications such as progressively deteriorating heart failure. In these cases, valvular correction with surgery may not be the optimal option because of multiple chronic illnesses and the use of medications. Although transcatheter AV implantation (TAVI) is a well-known, established alternative method to surgical replacement in patients with severe aortic stenosis, it can be a good alternative in patients with severe AR in whom valvular surgery is not an option due to comorbidities. Here, we presented a case of TAVI in a patient with cirrhosis, hepatocellular cancer, and symptomatic severe AR due to <i>S. infantarius</i> IE.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"43-47"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retroperitoneal Paraganglioma Presenting as Acute Coronary Syndrome: A Rare Case Report and Literature Review.","authors":"Abhishek Mishra, Shalendra Singh, Ankit Mathur, Anil Kumar Abbot","doi":"10.4103/heartviews.heartviews_117_23","DOIUrl":"10.4103/heartviews.heartviews_117_23","url":null,"abstract":"<p><p>Paragangliomas are catecholamine-secreting tumors arising from the sympathetic and parasympathetic ganglia. Here, we describe a case in which a young man who had visited the emergency room complaining of headache and shortness of breath was later found to have acute coronary syndrome with accompanying cardio-pulmonary complications necessitating immediate cardiac intervention. Later on, during further management, he was diagnosed with a retroperitoneal paraganglioma. Thus, we try to emphasize the need for a high clinical index of suspicion and urgent radio-imaging for diagnosing this relatively rare clinical entity to prevent fatal outcomes or any long-term morbidity.</p>","PeriodicalId":32654,"journal":{"name":"Heart Views","volume":"26 1","pages":"62-66"},"PeriodicalIF":0.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}