Pigment International最新文献

{"title":"A split-face study to evaluate the efficacy of Nd:YAG laser versus radiofrequency cauterization for the treatment of ephelides on face","authors":"Ambuj Singh, T. Goyal, Pooja Singh","doi":"10.4103/pigmentinternational.pigmentinternational_54_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_54_20","url":null,"abstract":"Background: Until recently, the removal of ephelides on face was predominantly carried out by using dermabrasion, chemical peeling, and radiofrequency cauterization. As these treatment modalities caused undesirable side effects such as scarring, this study is being performed to compare the effect of ND:YAG laser and radiofrequency to remove ephelides with laser showing better result and fewer side effects. Materials and methods: The present study was conducted in the department of dermatology, venerology, and leprology during the period 2017 to 2019 after obtaining clearance from Board of Studies and Ethical committee. Patient was thoroughly examined on the basis of history and examination for a confirm diagnosis. After confirming the diagnosis, the patient’s face was divided into left and right sides. On to the right-sided freckles of the face, radiofrequency cauterization was carried out and on left part, Nd:YAG was performed. The objective parameters were estimated at the end of 1 month using global improvement scale and also by evaluating patient’s satisfaction score. Photographs of both sides of the face were taken at 0, 1 week, and at 1 month under consistent background, position, and lighting and compared with the pretreatment images. Results: The study population consisted of 9 (18%) males and 41 (82%) females. Distribution of global improvement scores 3 and 4 was significantly more among Nd:YAG laser (65.0% and 10.0%, respectively) compared to radiofrequency ablation (2.5% and 0.0%, respectively). Mean freckle area severity index (FASI) score post-treatment and reduction in score were significantly more among Nd:YAG laser compared to radiofrequency ablation. Erythema, hyperpigmentation, and hypopigmentation were significantly more among radiofrequency ablation. Conclusion: Nd:YAG laser showed satisfactory result in removing freckles in comparison to radiofrequency ablation.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"136 1","pages":"39 - 45"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90627934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Premature graying of hair observed as the commonest cutaneous association in vitiligo in a comparative cross-sectional study: a component to be pondered","authors":"N. Divya, P. Prathap, N. Asokan","doi":"10.4103/pigmentinternational.pigmentinternational_17_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_17_21","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"41 6 1","pages":"59 - 62"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88748542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study of efficacy of intradermal tranexamic acid microinjections versus intradermal glutathione microinjections for treatment of facial melasma","authors":"Kanchan Kumawat, K. Bhatia, Jushya Bhatia, R. Kataria, C. Namdeo, Ankur Sarin","doi":"10.4103/pigmentinternational.pigmentinternational_13_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_13_20","url":null,"abstract":"Background Melasma is a hypermelanotic disorder, which poses therapeutic challenge. Tranexamic acid (TA) and glutathione are novel therapies for the treatment of melasma. Aim To compare the therapeutic efficacy of localized intradermal microinjections (mesotherapy) of TA versus microinjections of glutathione for the treatment of melasma. Methods This prospective, comparative study was carried out to assess the therapeutic efficacy of TA and glutathione in 64 patients with dermal melasma after obtaining written informed consent, over a period of 12 weeks. Face of the patient was divided into two halves (split face); right cheek was injected with TA and the left with glutathione, at baseline (zero), 4th, 8th, and 12th weeks. The treatment response was assessed by using visual analog scale (VAS); photographs were taken to ascertain the improvement and its percentage was calculated. A parametric test, Student t test, and Z test were applied wherever applicable. P-value of <0.05 was considered statistically significant. Results Out of 64 enrolled, 50 patients completed the study and it was found that the reduction in VAS score from baseline to 8th week and baseline to 12th week was significant in both the groups (P < 0.05). However, the mean difference in improvement percentage between baseline and 8th week and baseline and 12th week with TA was found to be more significant than glutathione. Conclusion This study revealed that both TA and glutathione intradermal microinjections are effective in the treatment of melasma but TA is more effective.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"9 1 1","pages":"46 - 50"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76054948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turban Dermatitis","authors":"Vignesh Narayan R, A. Bishnoi, M. Kumaran","doi":"10.4103/pigmentinternational.pigmentinternational_27_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_27_21","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"20 1","pages":"63 - 64"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73459774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of childhood vitiligo − a brief review","authors":"S. Raju, S. Kaur, E. Loganathan","doi":"10.4103/pigmentinternational.pigmentinternational_66_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_66_21","url":null,"abstract":"Vitiligo comprises of one of the commonest reasons for a dermatology consultation in the pediatric age group, worldwide. The incidence of childhood vitiligo varies from 1% to 8%, making it a significant pediatric condition. Various theories have been put forward to explain the occurrence of depigmentation in vitiligo, of which genetic factors play a predominant role in childhood vitiligo. The various modalities of treatment of childhood vitiligo are reviewed in this article. The management of vitiligo is extremely challenging, more so in the pediatric age group, as it can lead to significant psychologic trauma and dysregulation of social development in a child. The goals of management of childhood vitiligo should be aimed at addressing all these issues and achieving an optimum result out of the available modalities.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"36 1","pages":"14 - 24"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75297762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Café au lait macules and vitiligo: A conflicting coexistence","authors":"Vijayasankar Palaniappan, Jeyalakshmi Sankarapandian, K. Karthikeyan","doi":"10.4103/pigmentinternational.pigmentinternational_28_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_28_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75781050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eccrine poroma","authors":"G. Bhasin, S. Khatu, Nitin C Chaudhari","doi":"10.4103/pigmentinternational.pigmentinternational_24_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_24_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"28 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72407129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laugier–Hunziker syndrome: A case report","authors":"Zigu S Krishn, Yogesh Devaraj, M. Swaroop, R. Mallya, Neethu Nag, K. Reddy","doi":"10.4103/pigmentinternational.pigmentinternational_12_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_12_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82358930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy in Vitiligo: An emerging armamentarium in diagnosis and activity assessment","authors":"Guneet Awal, J. Kaur, K. Kaur","doi":"10.4103/pigmentinternational.pigmentinternational_4_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_4_21","url":null,"abstract":"Context: Vitiligo is an autoimmune depigmentary disorder characterized by loss of epidermal melanocytes. It can be diagnosed clinically, however, dermoscopy aids in its differentiation from other hypopigmentary and depigmentary conditions and also helps in evaluating disease activity. Aims: To study the dermoscopic patterns of vitiligo and evaluate their correlation with disease activity. Settings and Design: This is a cross-sectional and observational study conducted in the outpatient department of dermatology of a tertiary care hospital at Sri Amritsar. Methods and Materials: Fifty patients complaining of depigmented lesions were diagnosed clinically for vitiligo. Histopathological confirmation was done in difficult to diagnose cases. Patients with clinically stable vitiligo, unstable vitiligo, and vitiligo under treatment were included. A dermoscopic examination was done with a Dermlite DL4 dermoscope. The photographs were taken using a standard phone and the dermoscopic findings were documented.Statistical Analysis Used: The results were tabulated and expressed as percentages. The Pearson correlation coefficient was calculated between dermoscopic patterns of vitiligo and disease activity. Results: On examination with the dermoscope, pigmentary patterns observed were marginal hyperpigmentation, perifollicular pigmentation, reticulate hyperpigmentation, and altered pigment network. Morphological patterns seen on dermoscopy included leukotrichia, micro-Koebner phenomena, polka dots, and starburst appearance. Conclusions: Marginal hyperpigmentation, perifollicular pigmentation, and reticulate pigmentation were the markers of disease stability. Leukotrichia was seen in patients of stable vitiligo majority being treatment refractory. Altered pigment network, micro-Koebner phenomena, starburst appearance, and polka dots indicated unstable vitiligo. Presence of erythema and telangiectasias indicated response to treatment. Hence, dermoscopy can be used as an effective tool for the diagnosis of vitiligo and evaluation of disease activity.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"22 1","pages":"25 - 32"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86949025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitiligo: an uncommon cutaneous manifestation of graft versus host disease","authors":"Preema Sinha, A. Sinha, S. Radhakrishnan, J. Bhatia","doi":"10.4103/pigmentinternational.pigmentinternational_30_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_30_20","url":null,"abstract":"Graft versus host disease (GVHD) is the most serious complication of hematopoietic stem cell transplantation. Skin is the most commonly affected organ, in both acute and chronic GVHD with a variable clinical spectrum of presentation with the typical skin lesions being either lichenoid or sclerodermatous. Antibodies developing in chronic GVHD act as triggering factors in the development of autoimmune diseases and can manifest as vitiligo that is an autoimmune disease resulting in melanocyte destruction. Vitiligo as sequelae and manifestation of GVHD is infrequently reported in the literature. Herein, we report the case of a lady who developed vitiligo post hematopoietic stem cell transplant.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"86 1","pages":"51 - 54"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85980658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}