Pigment International最新文献

{"title":"Greenish discoloration over the nape of neck","authors":"Shreya K Gowda, Biswanath Behera, Vishal Thakur","doi":"10.4103/pigmentinternational_21_24","DOIUrl":"https://doi.org/10.4103/pigmentinternational_21_24","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"8 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141919549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Greenish discoloration over the nape of neck","authors":"Shreya K Gowda, Biswanath Behera, Vishal Thakur","doi":"10.4103/pigmentinternational_21_24","DOIUrl":"https://doi.org/10.4103/pigmentinternational_21_24","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141919025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series","authors":"Taru Garg, Riaz Ahmed, Anuja Rao, V. Mendiratta","doi":"10.4103/pigmentinternational_46_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational_46_21","url":null,"abstract":"Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas. It is a cosmetically distressing pigmentary disorder often posing a therapeutic challenge. There are few reports showing efficacy of oral isotretinoin and topical tacrolimus in LPP. However combination of both these therapeutic modalities has not been described earlier. Herein we report a series of 10 patients who showed good response to combination of oral isotretinoin (20 mg/day) and topical 0.1% tacrolimus ointment.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"123 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of congenital vitiligo in a neonate with a review of literature","authors":"Debasmita Behera, Farheen Begum, C. Raj, Garima Manocha","doi":"10.4103/pigmentinternational_24_24","DOIUrl":"https://doi.org/10.4103/pigmentinternational_24_24","url":null,"abstract":"Congenital vitiligo is a very rare entity, but cases in infancy have been reported. We are presenting the case of a 2-month-old male infant who came to us with complaints of multiple progressive white patches over the body since birth. The lesions showed white accentuation with fluorescence under a Wood’s lamp. There was a positive history of vitiligo in the maternal grandmother. The infant was successfully treated with topical pimecrolimus 1% cream. Our case in point contributes to the limited pool of studies on congenital vitiligo (nine cases reported till date) and lends credibility to the theory that, in genetically vulnerable individuals, the autoimmune process may begin in utero.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":" 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatopathia pigmentosa reticularis: a rare case report","authors":"Suhail Khan, Saurabh Raut, E. Loganathan","doi":"10.4103/pigmentinternational_4_24","DOIUrl":"https://doi.org/10.4103/pigmentinternational_4_24","url":null,"abstract":"Dermatopathia pigmentosa reticularis (DPR) is a very rare ectodermal disorder with autosomal dominant mode of inheritance. It is associated with a mutation in the keratin 14 gene on chromosome 17. It is characterized by a diagnostic triad of generalized reticulate hyperpigmentation, non-cicatricial alopecia, and onychodystrophy. We hereby report a case of a 26-year-old female who presented with reticulate hyperpigmentation all over the body, diffuse non-cicatricial alopecia, and onychodystrophy. Apart from this triad, she also had poorly developed dermatoglyphics.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":" 667","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A curious case of reticulate pigmentation","authors":"Sruthy Mathew, Aravind Sivakumar, L. Chandrashekar","doi":"10.4103/pigmentinternational_41_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational_41_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"116 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of therapeutic efficacy of tranexamic acid compared to modified Kligman formula in the management of melasma","authors":"Meda Susmitha, Kethireddy S. Divya, Dasika Subbarao, Bendapudi Venkata Ramachandra","doi":"10.4103/pigmentinternational_55_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational_55_22","url":null,"abstract":"\u0000 Background: Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Melasma is an acquired non-inflammatory hypermelanosis of multifactorial etiology with significant cosmetic deformity. Different treatment modalities have been tried in different studies with varying outcomes. Recent clinical trials with tranexamic acid (TXA) are promising. Objective: To compare the therapeutic efficacy of TXA topical application after micro-needling and intralesional TXA with the modified Kligman formula in the management of melasma. Materials and Methods: This is a prospective, randomized, open-label study with a sample size of 45 patients with melasma fulfilling inclusion and exclusion criteria. They were randomly divided into three groups of 15 each. Group A individuals were advised to apply a modified Kligman formula daily at night for 3 months, Group B individuals weekly micro-needling followed by TXA application for 3 months, and Group C individuals intralesional TXA (4 mg/mL) weekly for 3 months. Clinical and dermoscopic images were taken at each visit, including modified Melasma Area Severity Index (MASI) scoring, patient global assessment, and physician global assessment to assess the clinical response. Results: Group A showed a 42% improvement in MASI score by the end of 12 weeks, Group B showed a 30% improvement, and Group C showed a 36% improvement. When statistically compared with the Analysis of Variance test, there was no significant difference (P = 0.62) between the three groups. However, in individual groups, there was a significant difference (P < 0.05) in MASI at 0 and 12 weeks. Dermoscopic images showed perilesional hypopigmentation and telangiectasias with a modified Kligman formula, which was not seen with TXA. Patient assessment score revealed satisfaction with the modified Kligman formula because of home application and lack of pain. Conclusion: The modified Kligman formula is found to be superior in the treatment of melasma, because of the synergistic activity of its components. However, it has its demerits of long-term usage like hypopigmentation and telangiectasias. Hence, TXA that showed comparable results with the Kligman formula can be used either as a primary modality or as an adjuvant supportive therapy for maintenance.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"118 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral hypomelanosis of Ito: Report of two cases","authors":"S. Joshi, Ramesh K. Kushwaha, Harshita Shrivastava, S. Jain","doi":"10.4103/pigmentinternational_55_23","DOIUrl":"https://doi.org/10.4103/pigmentinternational_55_23","url":null,"abstract":"Hypomelanosis of Ito, also known as incontinentia pigmenti achromians of Ito, is a rare neuroectodermal disorder often associated with mental retardation and epilepsy. Here we report two patients with bilateral hypopigmented streaks and patches.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Clinico-dermoscopic study and comparative evaluation with Wood’s Lamp as a diagnostic tool in patients with melasma’","authors":"A. Khadka, Sabina Bhattarai, Sagar Gc","doi":"10.4103/pigmentinternational_17_23","DOIUrl":"https://doi.org/10.4103/pigmentinternational_17_23","url":null,"abstract":"\u0000 Background: Melasma is a common acquired facial hypermelanosis. While mostly diagnosable clinically, Wood’s lamp and dermoscopy can aid in differentiating melasma types based on pigment distribution. Aims: To study the clinico-dermoscopic distribution of melasma and compare it with Wood’s lamp finding. Methods: A total of 140 patients with melasma attending the Dermatology OPD of a tertiary care hospital over a duration of 12 months were included in this cross-sectional analytical study. Patients were subjected to clinical examination, Wood’s lamp examination, and dermatoscopic examination. Noted findings were recorded and analyzed for descriptive values and associations. Results: Among 140 patients, 123 were females and 17 were males, with a mean age of 33.49 ± 7.65 years. Clinically, 78 (55.7%) had centrofacial distribution, 55 (39.3%) had malar distribution, and 7 (5%) had a mandibular distribution of lesions. Wood’s lamp examination showed epidermal type in 64 (47.71%), mixed type in 60 (42.9%), and dermal type in 16 (11.4%). Dermoscopic examinations revealed an epidermal pattern in 79 (56.42%), a dermal pattern in 6 (4.2%), and a mixed type in 55 (39.28%). The most common dermoscopic finding was an exaggerated pseudoreticular network, followed by reticuloglobular pattern, arciform structures, and patternless hyperpigmentations, respectively. The association between color on clinical examination and melasma type by dermoscopy was significant (Cramer’s V = 0.535, P-value = 0.000). The degree of agreement between Wood’s lamp examination and dermoscopic examination was significant with a moderate agreement, (κ = 0.548 P < 0.0005). Conclusion: Although dermoscopy can be used more effectively, both Wood’s lamp and dermoscopy can aid in the diagnosis and determination of pigment distribution in melasma, promising effective intervention, and prognosis assertion.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":" 1142","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reticulate acropigmentation of Kitamura and Dowling-Degos disease overlap: a rare case report","authors":"Anukriti Yadav, Rashmi Sarkar, Surabhi Sinha, V. Mendiratta, Kiran Agarwal","doi":"10.4103/pigmentinternational_10_24","DOIUrl":"https://doi.org/10.4103/pigmentinternational_10_24","url":null,"abstract":"Reticulate acropigmentation of Kitamura (RAK) and Dowling-Degos disease (DDD) belong to the rare heterogeneous group of reticulate pigmentary disorders. They are inherited as an autosomal dominant trait with variable penetrance and are characterized by the presence of hyperpigmented macules coalescing in a reticular fashion. We hereby describe a 29-year-old male patient having hyperpigmented macules on the neck, axillae, dorsum of the hands and feet, along with palmar pitting. A clinicopathological overlap of both these entities (RAK and DDD) was seen in this patient, which is a rare occurrence, indicating that they are two different phenotypic presentations of a single disease.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"82 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140677078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}