作为黄褐斑患者的诊断工具,皮肤镜临床研究及与伍德灯的比较评估

A. Khadka, Sabina Bhattarai, Sagar Gc
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引用次数: 0

摘要

背景:黄褐斑是一种常见的后天性面部黑色素沉着症:黄褐斑是一种常见的后天性面部黑色素沉着症。虽然大多可通过临床诊断,但伍德灯和皮肤镜可根据色素分布帮助区分黄褐斑类型。目的:研究黄褐斑的临床皮肤镜分布,并将其与伍德灯的发现进行比较。方法:对 140 名黄褐斑患者进行皮肤镜检查:在这项横断面分析研究中,共纳入了 140 名在一家三级医院皮肤科门诊就诊的黄褐斑患者,他们的就诊时间长达 12 个月。患者接受了临床检查、伍德灯检查和皮肤镜检查。研究人员记录了注意到的结果,并对其描述值和关联性进行了分析。研究结果140 名患者中,女性 123 人,男性 17 人,平均年龄(33.49±7.65)岁。从临床上看,78 例(55.7%)的病变分布在面中部,55 例(39.3%)分布在颊部,7 例(5%)分布在下颌部。伍德灯检查显示,64 例(47.71%)为表皮型,60 例(42.9%)为混合型,16 例(11.4%)为真皮型。皮肤镜检查显示,79 例(56.42%)为表皮型,6 例(4.2%)为真皮型,55 例(39.28%)为混合型。最常见的皮肤镜检查结果是夸张的假性网状结构,其次分别是网状红斑、弧形结构和无模式色素沉着。临床检查的颜色与皮肤镜检查的黄褐斑类型之间存在显著关联(Cramer's V = 0.535,P 值 = 0.000)。伍德氏灯检查和皮肤镜检查之间的一致程度显著,为中度一致(κ = 0.548,P < 0.0005)。结论:虽然皮肤镜的使用更有效,但伍德灯和皮肤镜都能帮助诊断和确定黄褐斑的色素分布,有望进行有效干预和预后断言。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
‘Clinico-dermoscopic study and comparative evaluation with Wood’s Lamp as a diagnostic tool in patients with melasma’
Background: Melasma is a common acquired facial hypermelanosis. While mostly diagnosable clinically, Wood’s lamp and dermoscopy can aid in differentiating melasma types based on pigment distribution. Aims: To study the clinico-dermoscopic distribution of melasma and compare it with Wood’s lamp finding. Methods: A total of 140 patients with melasma attending the Dermatology OPD of a tertiary care hospital over a duration of 12 months were included in this cross-sectional analytical study. Patients were subjected to clinical examination, Wood’s lamp examination, and dermatoscopic examination. Noted findings were recorded and analyzed for descriptive values and associations. Results: Among 140 patients, 123 were females and 17 were males, with a mean age of 33.49 ± 7.65 years. Clinically, 78 (55.7%) had centrofacial distribution, 55 (39.3%) had malar distribution, and 7 (5%) had a mandibular distribution of lesions. Wood’s lamp examination showed epidermal type in 64 (47.71%), mixed type in 60 (42.9%), and dermal type in 16 (11.4%). Dermoscopic examinations revealed an epidermal pattern in 79 (56.42%), a dermal pattern in 6 (4.2%), and a mixed type in 55 (39.28%). The most common dermoscopic finding was an exaggerated pseudoreticular network, followed by reticuloglobular pattern, arciform structures, and patternless hyperpigmentations, respectively. The association between color on clinical examination and melasma type by dermoscopy was significant (Cramer’s V = 0.535, P-value = 0.000). The degree of agreement between Wood’s lamp examination and dermoscopic examination was significant with a moderate agreement, (κ = 0.548 P < 0.0005). Conclusion: Although dermoscopy can be used more effectively, both Wood’s lamp and dermoscopy can aid in the diagnosis and determination of pigment distribution in melasma, promising effective intervention, and prognosis assertion.
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