Pigment InternationalPub Date : 2023-05-01DOI: 10.4103/pigmentinternational.pigmentinternational_15_22
A. Rao, N. M, Sanchi Gupta, Santoshi G
{"title":"Segmental pagetoid Spitz nevus involving head and neck region: An uncommon presentation","authors":"A. Rao, N. M, Sanchi Gupta, Santoshi G","doi":"10.4103/pigmentinternational.pigmentinternational_15_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_15_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"48 1","pages":"132 - 134"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78646450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-05-01DOI: 10.4103/pigmentinternational.pigmentinternational_51_21
Suresh Rangegowda, Gouhare Afshan, R. Channakeshavaiah, Soumya Hegde, Vinay K. Nirvanappa, P. Nagesha
{"title":"Knowledge and attitude of general public toward vitiligo: a study from a tertiary care hospital from South India”","authors":"Suresh Rangegowda, Gouhare Afshan, R. Channakeshavaiah, Soumya Hegde, Vinay K. Nirvanappa, P. Nagesha","doi":"10.4103/pigmentinternational.pigmentinternational_51_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_51_21","url":null,"abstract":"Background: Vitiligo is a common, autoimmune acquired disorder of the skin, which causes milky white depigmented macules on various parts of the body. These macules are commonly aesthetically disfiguring, which may significantly decrease their quality of life. Common peoples’ misconceptions and undue apprehension associated with vitiligo are the result of inadequate knowledge about this otherwise benign and harmless condition. Aims and objectives: To document the prevalent knowledge, attitude, and practices of general population on vitiligo. Materials and methods: It is a cross-sectional study of 3 months duration. A total of 500 people from the general public visiting hospital who satisfied the inclusion criteria were recruited and were provided with a questionnaire devised in local language (Kannada) which included questions related to knowledge and attitude toward vitiligo patients. The collected data were tabulated and assessed using descriptive statistics. Results: Statistically significant difference was noted in mean knowledge and attitude score between urban and rural subjects (P = 0.008, P < 0.001), respectively. Regression analysis showed gender, education, and age are the predictors of knowledge (P = 0.001, P < 0.001, P < 0.001), respectively. Education and domicile were the predictor of attitude (P < 0.001, P < 0.001), respectively. Conclusion: The study highlights that the availability of the different treatment options in the urban areas has increased the knowledge and attitude of public toward the condition. Thereby we conclude that the need of the hour is awareness program regarding knowledge and treatment options of vitiligo.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"42 1","pages":"113 - 119"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90553264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Periorbital hypermelanosis secondary to lichenoid dermatitis due to use of tobramycin eye drops","authors":"Pooja Arora, Niharika Dixit, Kabir Sardana, Minakshi Bharadwaj","doi":"10.4103/pigmentinternational.pigmentinternational_12_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_12_21","url":null,"abstract":"Drug induced lichenoid dermatitis is a rare cause of periorbital hyperpigmentation. Herein, we report a case of lichenoid pigmentation that occurred in an elderly female due to use of tobtramycin eye drops.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"33 1","pages":"120 - 122"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88439728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_65_21
Mary Augustine, V. John
{"title":"Childhood onset vitiligo − clinical profile and impact on quality of life of family members","authors":"Mary Augustine, V. John","doi":"10.4103/pigmentinternational.pigmentinternational_65_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_65_21","url":null,"abstract":"Background: Vitiligo, a chronic disease, is distressing for patients and family. There are only a few studies on childhood onset vitiligo that describe its prognosis. Aim: To study the clinical and epidemiologic features of childhood onset vitiligo and to assess its impact on quality of life (QoL) of family members. Methods: A cross-sectional study was carried out on patients with vitiligo, with onset before 12 years of age. Clinicoepidemiologic profile was recorded. QoL of family members was assessed using family dermatology life quality index (FDLQI). Results: Fifty-four patients with age ranging from 1.2 to 41 years were included. Mean age of onset was 6.68 ± 3.43 years. Generalized vitiligo was most common (33.33%), followed by segmental (31.48%), acrofacial (24.07%), mucosal (7.40%), universal (1.85%), and focal (1.85%) types. About 42% had mucosal involvement, oral mucosa in 27.78%, and genital mucosa in 14.81%. Leukotrichia was significantly more common in segmental vitiligo (SV) than nonsegmental vitiligo (NSV) (P = 0.000046). Of the 9 adult NSV patients, progressive disease was reported in 6 with 10 years duration and 2 with 20 years duration. Mean FDLQI was 7.02 ± 3.64; emotional distress having maximum score (1.09). There was no significant association between total FDLQI and age (P = 0.69), gender (P = 0.528), clinical type (P = 0.874), vitiligo disease activity (VIDA) score (P = 0.105), or site of involvement (P = 0.07). Conclusion: NSV can be progressive for many years; a fact to be kept in mind while planning management of childhood onset vitiligo. QoL of family is affected regardless of the clinicoepidemiologic profile.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"14 1","pages":"30 - 36"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87642562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_58_21
O. Ayanlowo, A. Akinkugbe, A. Onakoya, E. Otrofanowei, Ogogho Odiase, Y. Olumide
{"title":"Cross-sectional study on clinical profile and quality of life of individuals with occulocutaneous albinism in Lagos, Nigeria","authors":"O. Ayanlowo, A. Akinkugbe, A. Onakoya, E. Otrofanowei, Ogogho Odiase, Y. Olumide","doi":"10.4103/pigmentinternational.pigmentinternational_58_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_58_21","url":null,"abstract":"Introduction: Albinism is a genetic disorder of pigmentation with variable phenotypic presentations. Albinism occurs all over the world, with highest prevalence in sub-Saharan Africa. The most common type is oculocutaneous albinism (OCA), an autosomal recessive disorder. Albinism is associated with morbidity and mortality in Africans. This study aims to describe the epidemiology of OCA, clinical expressions, and effect on the quality of life (QoL). Methods: Individuals with albinism were invited through the albino foundations and dermatology clinic of Lagos University Teaching Hospital. Structured questionnaires were used to document demographic and clinical data: occupational history, sun exposure, sun protective behavior, knowledge of adverse effects of sun exposure, and QoL and features of photodamage. Results: A total of 142 Nigerians with albinism were recruited. The male to female ratio was 1:1.25. The median age was 22.5 and interquartile range 10.25 to 34. Knowledge of need for sun protection was found in 129 (90.8%): 81 (57%) had daily sun exposure and 61 (43%) had work exposure to sun. Use of sun protection was noted in 103 (72.5%). Overall, photodamage was found in 136 subjects (95.8%). Mean effect of albinism and photodamage on QoL was 6.34 ± 4.47 (standard deviation) corresponding to moderate effect on QoL and domain of “symptoms and feelings” was most affected. Conclusion: The prevalence of photodamage among people with albinism is high despite knowledge of sun protection. There is need for efforts on photoprotection by individuals with albinism and public health interventions.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"76 1","pages":"37 - 45"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86638683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_54_21
E. A. Abdul Latheef, S. Rahima, K. Muhammed, N. Riyaz
{"title":"A 4-year follow-up study of 20 cases of stable localized childhood vitiligo treated by autologous, noncultured melanocyte–keratinocyte cell transplantation","authors":"E. A. Abdul Latheef, S. Rahima, K. Muhammed, N. Riyaz","doi":"10.4103/pigmentinternational.pigmentinternational_54_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_54_21","url":null,"abstract":"Background: Vitiligo is a common skin disease affecting 1% to 2% of general population. Even though different modalities of treatment available, it remains as a difficult disease to treat. Many cases remain stable after a period of medical therapy without any further response. For treating pediatric vitiligo, currently available and result providing therapies are limited. Surgical techniques are the only hope in such patients. Only limited studies are available regarding surgical interventions in childhood vitiligo. Aim: To evaluate the response of autologous, noncultured melanocyte–keratinocyte cell transplantation in childhood stable vitiligo. Methods: A retrospective analysis was conducted in 20 cases of stable localized childhood vitiligo (10 segmental and 10 focal) treated by autologous, noncultured melanocyte–keratinocyte cell transplantation. Serial photographs were taken from the first visit onwards. The patients were followed for a period of 4 years. The results were analyzed on a visual analog scale. Results: Out of total 20 cases, 11 had excellent (90–100%) response, 4 had good (60–89%), 2 had fair (25–59%), and 3 had poor response (0–24%). Age and sex of the patients and size and duration of lesions did not show significant influence on results of transplantation. Conclusion: This is a simple, safe, and effective surgical therapy for replenishing the missing melanocytes even in resistant cases of vitiligo. Only limited studies are there in childhood vitiligo. In spite of its invasive nature, it can be used to treat localized stable vitiligo in children.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"6 1","pages":"46 - 51"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76817208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_82_20
Ankita D Patil, Ajay Mahaputra Kumar, Kalyan Dalave, M. Deora, Devayani Pol
{"title":"Clinico-histopathological and dermoscopic features of Becker nevus: an analytical observational study from southwestern India","authors":"Ankita D Patil, Ajay Mahaputra Kumar, Kalyan Dalave, M. Deora, Devayani Pol","doi":"10.4103/pigmentinternational.pigmentinternational_82_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_82_20","url":null,"abstract":"Background: Becker nevus (BN), a common nevoid hamartoma, presents as a hypermelanotic often hypertrichotic plaque localized to the chest, shoulder, or back in the first two decades of life. Aims: The aim of the study was to evaluate clinicohistopathological and dermoscopic findings of BN in the Indian population. Methods: Thirty-five clinically diagnosed cases of BN were enrolled. Sample characteristics, clinicohistopathological findings, dermoscopic findings, and developmental abnormalities were noted and an observational analytical study was carried out. Results: The mean age of the patients was 18.9 years and 28 (80%) were Males. BN was present since birth in 12 (34.3%), developed in the first decade in 5 (14.3%), and in the second decade in 18 (51.4%). Common sites included the chest in 10 (28.6%), the face in 8 (22.9%), and the upper limb in 7 (20%). Hypertrichosis was observed in 24 (68.6%) and acneiform lesions in 2 (5.7%). Twenty-two (62.9%) patients had right-sided lesions. No developmental abnormalities were detected. Skin biopsy findings included hyperkeratosis in 25 (71.4%), acanthosis in 32 (91.4%), elongation of rete ridges in 32 (91.4%), basal layer pigmentation in 35 (100%), and smooth muscle hyperplasia in 4 (11.1%) patients. Dermoscopic findings included reticular brown lines (pigmentation network) in 32 (91.4%), perifollicular white color (perifollicular hypopigmentation) in 27 (77.1%), skin furrow hypopigmentation in 17 (48.6%), and focal hypopigmentation in 15 (48.6%) cases. Conclusions: Onset at birth and facial lesions are common in those of Indian ethnicity, while developmental abnormalities associated with BN are infrequent.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"133 1","pages":"24 - 29"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85612473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_15_23
Ajit B Janagond, A. Inamadar
{"title":"Pigmentation in chikungunya: An enigma to unravel","authors":"Ajit B Janagond, A. Inamadar","doi":"10.4103/pigmentinternational.pigmentinternational_15_23","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_15_23","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"1 1","pages":"1 - 3"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81378823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pigment InternationalPub Date : 2023-01-01DOI: 10.4103/pigmentinternational.pigmentinternational_12_23
Subburaj Kiruthika, J. Sejal, V. Keshavmurthy
{"title":"Cosmeceuticals in hyperpigmentary disorders","authors":"Subburaj Kiruthika, J. Sejal, V. Keshavmurthy","doi":"10.4103/pigmentinternational.pigmentinternational_12_23","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_12_23","url":null,"abstract":"Cosmeceuticals are hybrids between cosmetics and pharmaceuticals containing ingredients that modify the skin’s functions and enhance its appearance. They are a bridge between drugs and cosmetics for minor skin ailments. The lack of proper regulatory standards for cosmeceuticals makes it very important for the dermatologists to educate the patient regarding their safety, or consequences of lack of knowledge thereof. In hyperpigmentation disorders, cosmeceuticals specifically target melanocytes and block the important regulatory steps in melanin synthesis, especially tyrosinase. The various agents include arbutin, bakuchiol, ferulic acid, kojic acid, licorice root extract, nicotinamide, plant extracts, resorcinol, retinol, sunscreens, thiamidol, and vitamin C. Plant extracts have minimal side-effects and are gaining popularity. They include aloe vera extract, cinnamic acid, coffeeberry, flavonoids, grape seed extract, green tea extracts, marine algae extract, mulberry extract, N-acetyl glucosamine, orchid extract, pycnogel, soy and umbelliferone. There is a requirement for large randomised controlled trials to establish their efficacy and adverse effects. Patient follow-up and compliance are the cornerstones of any skin therapy as any cosmeceutical use can produce gradual results when compared to conventional therapies. The PubMed database was searched using ‘hyperpigmentation disorders’ OR ‘melasma’ AND ‘cosmeceuticals’ as keywords. Abstracts were screened to include studies in the English language and those pertaining to the use of cosmeceuticals in hyperpigmentary disorders. In this review, we summarise the existing literature on the utility of cosmeceuticals in the treatment of hyperpigmentary diseases.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"1 1","pages":"14 - 23"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86483016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}