Pigment International最新文献

{"title":"Frictional melanosis and macular amyloidosis – exploring the link","authors":"A. Kombettu, Chethana Gurumurthy, Vinutha Rangappa, V. Shastry","doi":"10.4103/pigmentinternational.pigmentinternational_5_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_5_22","url":null,"abstract":"Frictional melanosis is a condition that is often encountered in dermatology practice. The acquired pigmentary disorder has clinical similarity to the condition termed macular amyloidosis. These two entities have etiological-epidemiological and clinical overlap. Dermoscopy and histopathology can demonstrate subtle differences. The review is an attempt to understand the different etiological aspects proposed for these conditions. We discuss the clinical features of the two conditions, dermoscopic features and histopathological changes. It is imperative for dermatologists to be aware of the similarities and the differences between the two entities for their better management.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"10 1","pages":"166 - 175"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79830474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of dermoscopy in patients of melasma in a tertiary care centre in North India","authors":"N. Puri, S. Gill, Sumir Kumar, B. Brar, Anahita Chahal","doi":"10.4103/pigmentinternational.pigmentinternational_84_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_84_20","url":null,"abstract":"Aims and Objectives: The aim of the study is to determine dermoscopic findings of melasma after evaluating them based upon clinical examination and to correlate each clinical picture with dermoscopic findings. Materials and methods: Various patients of melasma from December 2019 to December 2020 were enrolled from outpatient department. Detailed history was taken. The dermoscopic examination and photographic documentation of clinical as well as dermoscopic picture was done and findings were noted. Results: We enrolled 50 patients in study including 80% females and 20% males. Mean age of melasma in our study was 31.28 years. Mostly the patients were farmers and housewives with the most common precipitating factor being sun exposure.Twenty patients on clinical examination along with Wood’s lamp showed epidermal pattern, 18 patients showed mixed pattern, and 12 patients had dermal pattern. On dermoscopy, melasma showed perifollicular sparing in all patients (100%), but in 36 patients, along with perifollicular sparing, it also showed perifollicular pigmentation in some areas, granular pattern in 38 patients, globular pattern in 42 patients, blotches in 36 patients, telangiectasias in 30 patients, arcuate pattern in 32 patients, and annular in 12 patients.The frequency of findings was nearly similar in all three three types except for the arcuate pattern. In the dermal pattern, nearly 83% patients (P = 0.1) showed arcuate pattern as compared to 40% (P = 0.004) in epidermal pattern. Limitations: A larger sample size is required. Also, since a few of the patients were already on topical corticosteroids, it may have affected the dermoscopic findings. Conclusion: Dermoscopy is a noninvasive tool that can be used to diagnose and differentiate it from other disorders of hyperpigmentation, but it cannot be used to classify melasma into epidermal, dermal, or mixed pattern.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"155 1","pages":"176 - 181"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88196379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lichen planus pigmentosus in linear and zosteriform pattern along the lines of Blaschko: a rare presentation","authors":"S. Dhar, Abhishek De, Aarti Sarda, S. Dhar","doi":"10.4103/pigmentinternational.pigmentinternational_42_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_42_21","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"42 1","pages":"225 - 226"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78204676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutraceuticals in vitiligo: not just “designer” foods","authors":"P. Arora","doi":"10.4103/pigmentinternational.pigmentinternational_54_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_54_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"96 1","pages":"147 - 150"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80942505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case control study on the role of interleukin 17 in the pathogenesis of vitiligo","authors":"Priyanka Karagaiah, L. Budamakuntla","doi":"10.4103/pigmentinternational.pigmentinternational_3_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_3_21","url":null,"abstract":"Background: Interleukin 17 (IL-17) has recently been implicated in the pathogenesis of vitiligo by many studies but it is unclear whether it has any definitive role in causing depigmentation. IL-17 inhibitors have already been used in other inflammatory disorders with good results and may prove to be a valuable therapeutic modality in vitiligo. Thus, this study aims at adding to the existing data on the role of IL-17 in the pathogenesis of vitiligo. Objectives: (1) To determine the correlation between IL-17 and the extent of body surface area involvement. (2) To determine the correlation between IL-17 and the severity of disease activity. (3) To determine the correlation between IL-17 and serum vitamin D levels. Methodology: Thirty-two clinically diagnosed patients with vitiligo and 26 age- and sex-matched controls who fulfill the inclusion criteria were enrolled in the study. After obtaining a detailed history, a complete dermatologic examination was performed and vitiligo area severity index (VASI) and vitiligo disease activity score (VIDA) were assigned. The baseline serum IL-17 level was measured using Raybiotech serum IL-17 enzyme-linked immunosorbent assay kit. Serum vitamin D was measured for all cases and controls. Results: In our study, the mean VASI score of all the patients was 6.32 ± 10.14 and the mean VIDA score was 1.97 ± 0.999. The mean serum IL-17 levels were 155.72 ± 79.412 pg/mL in patients with vitiligo compared to 102.73 ± 56.478 pg/mL of the controls, with a mean difference of 52.99 pg/mL and the difference was statistically significant (P = 0.008). Although, there is no significant correlation between the serum IL-17 levels with the VASI score, our study noticed slightly higher levels of IL-17 in generalized vitiligo and lowest levels were noticed in localized vitiligo. Limitations: Our study was limited by the small sample size of 32. Conclusion: Although, serum IL-17 levels were significantly higher in the patient group than the controls, there was no correlation with the disease extent or activity. Thus, it is difficult to establish a causal role of serum IL-17 in vitiligo.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"1 1","pages":"197 - 203"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82218261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioral pigmentation","authors":"Siddharth Bhatt, S. Neema, B. Vasudevan","doi":"10.4103/pigmentinternational.pigmentinternational_14_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_14_22","url":null,"abstract":"ABSTRACT Perioral pigmentation is a commonly encountered condition in the skin Out Patient Department (OPD), occurring due to a variety of primary as well as secondary causes. The affection of the perioral skin being readily visible negatively impacts the patient’s quality of life. As the etiology of perioral pigmentation is multifactorial, treatment modalities vary according to the cause. The perioral skin, because of its location close to the mouth, is exposed to various allergens associated with food, saliva, toothpaste, cosmetics, etc., which can all lead to allergic manifestations resolving with pigmentation. Certain other dermatoses like melasma can first present with pigmentation over the perioral region. Infections like chikungunya and dengue and infestation with Demodex mite can also lead to pigmentation at this site. Perioral pigmentation can also be a marker of underlying systemic disease. Localized lentigines-like pigmentation can be associated with various cancer predisposition syndromes like Peutz-Jeghers syndrome. Diffuse pigmentation can occur due to Addison disease, vitamin deficiencies, or can be drug-induced. All these causes of pigmentation are seen more commonly in type IV and V skin. Currently, very little literature is available elucidating the cause of perioral pigmentation and the diagnostic approach. This article reviews the causes of perioral pigmentation and highlights their important features.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"37 1","pages":"151 - 165"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81579932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ectopic Cushing syndrome presenting as hyperpigmentation","authors":"P. Arora, S. Mathachan","doi":"10.4103/pigmentinternational.pigmentinternational_16_21","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_16_21","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"74 1","pages":"234 - 235"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79856355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Chik sign” in chikungunya: three cases with dermoscopic findings","authors":"S. Chidambara Murthy, M. Shankar","doi":"10.4103/pigmentinternational.pigmentinternational_10_22","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_10_22","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"48 1","pages":"231 - 233"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86620132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyschromatosis universalis hereditaria with keratoacanthoma: a rare presentation","authors":"Veena Thimmappa, R. Anand, SachinS. Shabadi, N. Gangaiah","doi":"10.4103/pigmentinternational.pigmentinternational_78_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_78_20","url":null,"abstract":"","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"60 1","pages":"227 - 230"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91154255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pityriasis alba: current clinicoepidemiologic scenario in a rural tertiary care hospital in central India","authors":"Komal Ramteke, S. Kar, Safa Patrick, Ajinkya Sawant, Vivek Ambhore","doi":"10.4103/pigmentinternational.pigmentinternational_88_20","DOIUrl":"https://doi.org/10.4103/pigmentinternational.pigmentinternational_88_20","url":null,"abstract":"Background: Pityriasis alba (PA) is a common, benign skin disorder occurring predominantly in children and adolescents. It is characterized by the presence of multiple, ill-defined, hypopigmented patches with fine scaling particularly over the face. Aims and objectives: To study the clinical characteristics and epidemiologic parameters in the context of current scenario in a rural tertiary care hospital in central India. Materials and methods: We conducted a descriptive observational study over a period of 1 year. We studied 100 clinically diagnosed patients with PA of the age group 2 to 15 years during this study. Results: Most common age group of patients observed was 6 to 10 years. About 87% patients had Fitzpatrick skin type IV followed by type III (7%) and type V (6%). Male to female ratio was 1.17:1. Maximum patients belonged to class III (50%) followed by class IV (37%) and class V (10%) according to the modified Kuppuswamy socioeconomic status scale (2018). Maximum patients had age of onset ranging from 6 to 10 years. Clinical characteristics revealed that maximum patients had 0 to 5 patches, with a duration of 1 to 2 months most commonly over cheeks. Associated features such as itching, scaling, and erythema were present in 18%, 98%, and 1% of the patients, respectively. Pallor was observed in 28% patients. However, significant history of atopy was elucidated in only 21% of patients. Around 6% patients showed positive family history of having PA and 14% having a positive history of atopy in first-degree family members. Conclusion: Due to the easily visible hypopigmented patches most commonly over face, PA is a common cause of concern in pediatric age group. In recent times, possibility of multiple factors other than atopy should be kept in mind while thinking of the associating or implicating factors which will lead to proper management of this pigmentary disorder.","PeriodicalId":32636,"journal":{"name":"Pigment International","volume":"16 1","pages":"182 - 187"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72625578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}