Medical Science Pulse最新文献

{"title":"Cronkhite-Canada Syndrome Presenting with life-threatening protein-losing enteropathy: a case report","authors":"Tolga Olmez","doi":"10.5604/01.3001.0016.2286","DOIUrl":"https://doi.org/10.5604/01.3001.0016.2286","url":null,"abstract":"Background: Cronkhite Canada Syndrome (CCS) is a rare gastrointestinal polyposis syndrome. The diagnosis of CCS is made by clinical, endoscopic and histopathological findings. Chronic diarrhea, malnutrition, alopecia, skin hyperpigmentation, onychodystrophy, hypogeusia, protein loss due to chronic inflammatory changes in the intestinal mucosa are common findings.Nutritional support, high protein diet, antibiotics, correction of electrolyte imbalance, and corticosteroids are frequently used in CCS treatment. \u0000Aim of the study: Here we present a newly diagnosed Cronkhite Canada Syndrome patient who has suffered life-threatening protein loss.\u0000Material and methods: Medical documentation was used.\u0000Case report: A 62-year-old male patient presented with bloodless diarrhea, happening 8-10 times a day for 4 months, and general condition disorder. On admission, arterial blood pressure was 80/50 mm/hg, pulse was 110 per minute and body temperature was 38.8°C. In laboratory tests, total protein: 38 mg/dl and albumin: 20 g/L.Upper and lower gastrointestinal system (GIS) endoscopy revealed 2-20 mm polyps in the stomach, duodenum, colon, and a small amount in the distal esophagus. Pathological examination of polypectomy materials revealed edematous and inflamed lamina propria consisting of plasma cells, neutrophils and eosinophils.The patient benefited from total parenteral nutrition, high protein dietary supplementation, antibiotic therapy and was followed with upper and lower GIS endoscopy. \u0000Conclusions: CCS is a rare disease that can cause life-threatening hypoalbuminemia and requires close follow-up.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45139327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of a series of trichloroacetic acid treatments and its effect on sebum levels and acne scars: a case report.","authors":"Ewa Adamczyk, Karolina Chilicka, Monika Rusztowicz","doi":"10.5604/01.3001.0016.2119","DOIUrl":"https://doi.org/10.5604/01.3001.0016.2119","url":null,"abstract":"Background: Acne vulgaris is a condition that most often appears during adolescence and can last from a few to over a dozen years. Unpleasant remnants of acne include post-inflammatory hyperpigmentation and acne scars, which often result in a reduced quality of life and can interfere with sufferers’ ability to function in society. \u0000Aim of the study: Assess the effectiveness of trichloroacetic acid (TCA) in reducing skin sebum levels (oiling) and smoothing acne scars.\u0000Case report: A 35-year-old female reported excessive oiliness of the skin and acne scars on both cheeks. Before and after TCA treatment, sebum levels were measured on the surface of the skin using a Sebumeter®. In addition, the cheek scars were graded using the Goodman and Baron scale. \u0000Conclusion: After a series of five treatments with TCA, there was a large reduction in sebum on the epidermal surface, and acne scars were reduced on both cheeks.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47301792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary function test results and radiological findings 90-120 days after COVID-19 pneumonia: a single-center retrospective study","authors":"H. Dirol, G. Ozbey, O. Ozbudak, A. Arslan","doi":"10.5604/01.3001.0016.1336","DOIUrl":"https://doi.org/10.5604/01.3001.0016.1336","url":null,"abstract":"Background: Survivors of Coronavirus Disease 2019 (COVID-19) pneumonia may have permanent loss of lung function and radiological sequelae. There is a need for markers that predict patients for whom follow-up is required. Aim of the study: To identify the risk factors associated with post-COVID-19 radiological and functional findings. Material and Methods: This is a single-center retrospective study performed in a university hospital. We obtained the data from all hospitalized patients with COVID-19 pneumonia. We included those who underwent pulmonary function tests (PFT) and chest computerized tomography (CT) 90-120 days later. We analyzed initial and peak laboratory results (C-reactive protein (CRP), d-dimer, ferritin, and fibrinogen), and the length of hospital and intensive care unit (ICU) stay. We examined the relationship between baseline data and radiological findings and PFT. Results: Fifty-six patients were included in this study. Of these, 31 (55.4%) were women. The mean age of the patients was 55.05 ± 13.29 years. The mean peak ferritin, fibrinogen, d-dimer, and CRP values recorded during hospitalization follow-up were 285.56 ± 339.82, 518.59 ± 186.93, 1.99 ± 5.69, and 98.94 ± 80.77, respectively. The mean length of hospital and ICU stay were 10.21 ± 8.01 and 8.38 ± 8.90 days, respectively. In 18 (32.1%) patients, we observed a restrictive pattern on PFT, and 22 (39.3%) patients had an abnormal diffusion test. In 21 (37.5%) patients we observed ground glass opacities and in 4 (7.1%) patients reticulation was seen on their chest CT. A multivariate logistic regression analysis revealed that the first visit and peak fibrinogen values were significantly associated with abnormal PFT (p = 0.049, R2 = 0.272), while ferritin and CRP levels at the first visit and peak levels were significantly associated with an abnormality on chest CT (p < 0.001, p = 0.05, respectively). Conclusions: High initial and peak ferritin, fibrinogen, and CRP levels were associated with persistent radiological findings on chest CT and abnormal PFT at 90–120 follow-up after COVID-19 pneumonia.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44242637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes distress in adult patients with type 1 and type 2 diabetes.","authors":"Dominika Kurza, E. Kobos","doi":"10.5604/01.3001.0016.1166","DOIUrl":"https://doi.org/10.5604/01.3001.0016.1166","url":null,"abstract":"Background: Diabetes is a chronic and demanding condition, exposing patients to complex physical and mental challenges, and making them particularly vulnerable to distress. Diabetes distress related to disease in diabetic patients is a term encompassing challenges associated with the psychosocial adaptation required of these individuals. Aim of the study: To assess distress in patients with diabetes mellitus. Material and methods: This study was conducted among 107 patients with type 1 and 2 diabetes mellitus reporting for follow-up at a diabetes clinic. The Diabetes Distress Scale (DDS) was used for data collection. Results: Moderate and severe diabetes distress was found in 36.4% and 15% of respondents in the study group, respectively. The total mean score for the DDS was 2.19. The largest percentages of respondents with high levels of distress were observed in patients with a financial situation rated lower than good (30.6%), those having less than secondary education (28.0%), and those under 30 years of age (27.8%). Patients with type 1 diabetes (26.9%), a disease duration > 30 years (30.8%), those using insulin pump therapy (30%) or CGM (Continuous Glucose Monitoring) and FGM (Flash Glucose Monitoring) systems (50%), and those showing ≥ 3 chronic diabetic complications (37.5%) experienced severe distress. Conclusions: Overall, diabetic patients showed a moderate level of distress. The greatest inconveniences caused by the disorder were associated with regimen-related distress and emotional burden. Rural patients with a lower level of education and a lower financial status showed higher levels of distress. Patients experiencing chronic complications from diabetes and those with higher levels of glycated hemoglobin also presented with more severe distress.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45989249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaginal haematoma as a postpartum complication: a case report","authors":"Katarzyna Janisiewicz, Barbara Mazurkiewicz, M. Stefaniak","doi":"10.5604/01.3001.0016.0922","DOIUrl":"https://doi.org/10.5604/01.3001.0016.0922","url":null,"abstract":"do uzupełnienia\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44431872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stationary rehabilitation robot and functional electrostimulation for the treatment of patients in the initial six months after stroke: a randomized controlled trial","authors":"Kamila Niewolak, P. Pecyna, Jolanta Piaskowska, L. Piejko, W. Marszałek, M. Baumgart, Aleksandra Bula, A. Polak","doi":"10.5604/01.3001.0016.0865","DOIUrl":"https://doi.org/10.5604/01.3001.0016.0865","url":null,"abstract":"Background: Results from studies investigating the effects of rehabilitation robots, including those using robots combined with functional electrostimulation (FES), on gait quality and postural control post-stroke are conflicting. Therefore, the evidence supporting the use of this approach to rehabilitation remains inconclusive and further research is required into how robotic therapy and FES can improve gait function and postural control at different times after stroke. Aim of the study: To gain knowledge on the effectiveness of stationary robotic exercises, and robotic exercises combined with FES of the lower extremity muscles, on activities of daily living, gait quality, postural control, and quality of life, in people who were between one and six months post-stroke. Material and Methods: A randomized controlled clinical pilot study was conducted. Forty-three post-stroke patients hospitalized at a rehabilitation center were randomly assigned to the following three groups: the GEO Group, for whom stationary robotic exercises were provided, the GEO+FES Group, for whom stationary robotic exercises were provided in combination with FES, and the Control Group, for whom conventional overground gait training was provided. Exercises were undertaken by all groups for 20 minutes a day, six days a week, for three weeks. In addition, all patients were provided with basic post-stroke therapy based on the principles of best clinical practice. All patients were assessed for stroke symptoms before and after therapy using the National Institutes of Health Stroke Scale (NIHSS), for independence in activities of daily living using the Barthel Index, and for quality of life using the Stroke Impact Scale Questionnaire. Static and dynamic postural control and gait performance were assessed using the Berg Balance Scale, the Timed Up and Go Test, the Functional Reach Test, and the 10 Meter Walk Test. Static postural control and gait quality were also assessed using a treadmill with a stabilometric platform. Results. Exercising on a stationary robot, both with and without FES of the lower extremity muscles, contributed to a statistically significant reduction in stroke symptoms (NIHSS, p<0.05). Additionally, exercising on a stationary robot without FES application significantly improved patient quality of life (p<0.05). However, these effects were not significantly different between the experimental and control groups. Conclusions. Stationary robotic exercise, either with or without FES, can be used as a substitute for traditional overground gait training to reduce stroke symptoms and improve quality of life in the first six months post-stroke. They can also be used as exercises to augment standard post-stroke therapy.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42157146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psycho-social working conditions of nursing, medical and paramedic staff in a hospital emergency department","authors":"A. Lisowska, Katarzyna Szwamel, Arkadiusz Wilczek, Krzysztof Tomsza","doi":"10.5604/01.3001.0016.0725","DOIUrl":"https://doi.org/10.5604/01.3001.0016.0725","url":null,"abstract":"Background: A hospital Emergency Department (ED) is a working place in which numerous working conditions evoke various organisational and operational stressors affecting medical staff working there.\u0000Aim of the study: Analysing the psycho-social working environment in nursing, paramedic and medical staff in a specific hospital ED and, in particular, examining 1) work requirements, 2) levels of control, 3) psycho-physical wellbeing and 4) changes expected by the staff.\u0000Material and methods: The research was conducted among 69 employees of ED (nursing, paramedic and medical staff) in the University Clinical Hospital in Opole. A standardized Psychosocial Working Conditions Questionnaire (PWCQ) was applied. \u0000Results: The average score were as follows: at the demands scale 94.99 points, at the control scale 59.26 pts, at the social support scale 48.94 pts, at the social support scale 48.94 pts, at desirable changes scale 75.32 pts. The length of service in the job correlated negatively with the support received at workplace (r= - 0.308, p=0.01). The necessity for changes at workplace was stronger in the residents of villages and towns below 100 000 residents (p=0.007). The material status of the respondents had a statistically significant correlation (p<0.05) with the answers collected in each PWCQ questionnaire subscale. The support received at workplace was significantly higher in the groups of paramedics (51.11±8.48) and doctors (52.95±13.66) than in nurses (44.39±10.26), p=0.005.\u0000Conclusions: Due to numerous stressors present at EDs and psycho-social working conditions, employers ought to make some effort to modify them.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42492967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Setting health training objectives based on the assessment of preferred areas of health behavior in a group of active women with chronic back pain: a pilot study of the cross-sectional research","authors":"M. Kałwa, Renata Myrna-Bekas, Urszula Dębska","doi":"10.5604/01.3001.0016.0566","DOIUrl":"https://doi.org/10.5604/01.3001.0016.0566","url":null,"abstract":"Background: The systematicity of health training (HT) for a participant with back pain still remains a challenge, while the regularity of exercises is an important objective of HT. \u0000Aim of the study: Getting to know the health determinants of active women with chronic back pain (ChBP), assessing the degree of variation in the hierarchy of health criteria, and their areas according to the length of HT. \u0000Material and methods: Women (n = 159; 19–76 years old) were divided into three groups according to their length of training: A — less than 2 years and/or unsystematic, B —systematic 2–4 years; C — systematic for more than 4 years. List of Health Criteria Questionnaire by Zygfryd Juczyński. \u0000Results: Women from group A place health in the area related to the maintenance of the condition. The ladies from group B are focused on a specific health outcome. The women from group C understand that health is the need to follow a specific process and to work towards a defined goal. \u0000Conclusions: Attendance during the entire training cycle can be used to assess a participant’s understanding of HT goals. The motives for HT depend on the length of training. In the beginners’ group, other educational arguments should be used to build awareness of the long-term goals of HT.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42214879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor unit involvement in scalene, strenocleidomastoid, and rectus abdominis muscles during eupnea, tachypnea, and bradypnea of sedentary young male adults: an observational study","authors":"Susmit Roy Chowdhury, R. Pathak, P. Chatterjee, A. Bandyopadhyay","doi":"10.5604/01.3001.0016.0482","DOIUrl":"https://doi.org/10.5604/01.3001.0016.0482","url":null,"abstract":"Background:\u0000It is well-established that extra-diaphragmatic muscles participate in respiration depending on the physiological situation. Even in clinical conditions where the diaphragm cannot act optimally, extra-diaphragmatic muscles can compensate for the breathing mechanics.\u0000Aim of the study:\u0000This study aims to determine the role of motor units in various respiratory conditions by monitoring the motor unit discharge in the scalene, sternocleidomastoid, and rectus abdominis during eupnea, tachypnea, and bradypnea using surface electromyography (sEMG). \u0000Material and methods: \u0000In this study, 28 healthy, sedentary males without a history of ailments participated. Using sEMG, the motor unit discharges from the scalene, sternocleidomastoid, and rectus abdominis were measured in three breathing patterns: normal breathing, hyperventilation, and intermittent breath retention. \u0000Results: \u0000The motor unit discharges of the rectus abdominis during eupnea, bradypnea, and tachypnea were significantly different, indicating that only the rectus abdominis' motor units were actively involved. Rectus abdominis muscle experienced changes in motor unit discharges that were highest and lowest during tachypnea and bradypnea, respectively [p<0.05]. \u0000Conclusions: \u0000This study has tried to evaluate the role of the motor units of three extra-diaphragmatic muscles in healthy sedentary young male adults with different respiratory conditions. This study has revealed that the rectus abdominis actively participates in the physiological conditions in young, sedentary healthy adult males. In scalene and sternocleidomastoid, active involvement of the motor unit has not been observed.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42858750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence on menstrual cycle phases on trunk flexion mobility assessed with finger floor distance test: a preliminary study","authors":"Maria Szajnowska","doi":"10.5604/01.3001.0015.9964","DOIUrl":"https://doi.org/10.5604/01.3001.0015.9964","url":null,"abstract":"Background: The menstrual cycle plays an important role in a woman's body and the relationship between different phases of the menstrual cycle and flexibility has not been well known. Aim of the study: This study aimed to examine whether the different phases of the menstrual cycle could affect trunk flexion mobility in young, healthy, physically active women who had not used hormonal contraception and had not received hormone treatment. Material and methods: In total, ten healthy female nulliparas aged 25 - 30 participated in the study. The inclusion criterion for the study was regular menstruation (25 - 35 cycle days). The exclusion criteria were: hormonal treatment, use of hormonal contraception, BMI > 25, and history of pregnancy. To assess trunk flexion mobility the finger floor distance test was used. The test was performed on each participant three times: during menstruation (follicular phase), during ovulation (ovulatory phase), and after day 15 of the cycle (luteal phase). Friedman ANOVA was used to determine the effect of the menstrual cycle phases on the finger floor distance test results. It was followed by Wilcoxon signed rank test. Results: There was a significant effect of the phases of the menstrual cycle on the results of the finger floor distance test (p = 0.03). Significantly higher values for the finger floor distance test result in the follicular phase as compared to the ovulatory phase were found (p = 0.02). Conclusions: The comparison of finger floor distance test results obtained in young healthy nulliparas in three phases of the menstrual cycle indicates decreased trunk flexion mobility in the follicular phase.\u0000\u0000","PeriodicalId":32604,"journal":{"name":"Medical Science Pulse","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48372830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}