Matrix Science Medica最新文献_第6页

Association of plasma zinc and prostate-specific antigen in patients with prostatic cancer in Khartoum 喀土穆地区前列腺癌患者血浆锌与前列腺特异性抗原的关系

Matrix Science Medica Pub Date : 2022-01-01 DOI: 10.4103/mtsm.mtsm_8_21

Ali Yahya Saeed, N. Mohammed, M. Mahdi

{"title":"Association of plasma zinc and prostate-specific antigen in patients with prostatic cancer in Khartoum","authors":"Ali Yahya Saeed, N. Mohammed, M. Mahdi","doi":"10.4103/mtsm.mtsm_8_21","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_8_21","url":null,"abstract":"Background: Prostate cancer is the most common visceral cancer in males, ranking as the second most common cause of cancer-related deaths in men older than 50 years of age, after carcinoma of the lung. It is predominantly a disease of older males, with a peak incidence between the ages of 65 and 75 years. This study aimed to estimate the plasma zinc level and plasma prostate-specific antigen (PSA) level in patients suffer from prostate cancer. Materials and Methods: A case–control study was conducted in Khartoum on 100 males aged more than 50 years old which were divided into 50 apparently healthy as control and 50 with prostate cancer as case. A 5 ml of blood specimens was collected in lithium heparin anticoagulants for the estimation of plasma zinc level using Buck model 210 VGP Atomic Absorption Spectrophotometer (East Norwalk, CT 06855) made in the USA and the plasma total PSA that was measured by immunoassay Sandwich principle HITACHI ROCHE COBAS E 411 (serial number 04641655190 V 13.0). Results: The mean level of plasma zinc was 0.35 mg/L ± standard deviation [SD] 0.14 in case and in control was 0.68mg/L ± SD 0.13, so the P value was 0.002 and PSA was 43.08 ng/ml ± SD 20.08 in case and 3.53 ng/ml ± SD 3.90 in control, so the P value was 0.000, the correlation between the level of plasma PSA with plasma zinc in patients with prostate cancer give R was 0.01 and R2 was 0.001. Conclusion: This study concluded that PSA is significantly increased in patients with prostate cancer and plasma zinc level is significantly decreased in patients with prostate cancer. However, it is statistically significant.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"30 1","pages":"23 - 26"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86731704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sudden sensorineural hearing loss among coronavirus disease-19 patients 冠状病毒病致突发性感音神经性听力损失19例

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_51_20

S. Swain, S. Thakur

{"title":"Sudden sensorineural hearing loss among coronavirus disease-19 patients","authors":"S. Swain, S. Thakur","doi":"10.4103/mtsm.mtsm_51_20","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_51_20","url":null,"abstract":"Coronavirus disease-19 (COVID-19) is a new pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus. COVID-19 patients often present with respiratory symptoms and death is the possible outcome. The potentiality for neuro-invasion by the SARS-CoV-2 is currently a subject of great debate. However, there is a paucity of information regarding impact of the SARS-CoV-2 on nervous system at the present moment. In fact, the impact of the coronavirus on the auditory system is little mentioned in the literature. Sudden sensorineural hearing loss (SSNHL) is rare symptom associated with COVID-19 infection. This hearing deterioration could be attributed to the damaging effects by viral infections on the outer hair cells of the cochlea but the exact mechanism is still unknown. Awareness about this nonspecific presentation like SSNHL in COVID-19 patients is often a challenge to a clinician for early management. Early identification of the SSNHL may be helpful for isolation of the patient and also protect their infectiousness in early period to prevent spread of the disease. Early identification of hearing impairment is also helpful for early medical treatment of SSNHL which can save the hearing. This article reviews the epidemiology, etiopathology, clinical presentations, investigations, and treatment of SSNHL in COVID-19 patients. This review article surely makes a baseline from where further prospective studies can be designed for this rare clinical entity in COVID-19 patients as not many studies are done.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"35 1","pages":"63 - 67"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74094533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Grand rounds: An effective tool in training medical undergraduate and postgraduate students 大查房:培养医学本科生和研究生的有效工具

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_10_21

S. Shrivastava, P. Shrivastava

引用次数: 0

Mechanisms action of tamoxifen in viral infections: Promising expected therapeutic branch 他莫昔芬在病毒感染中的作用机制:有希望的治疗分支

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_35_20

Falah Obayes Al-Khikani

引用次数: 0

Scabbard trachea: An incidental finding in the orthopedic clinic 鞘状气管:在骨科诊所偶然发现

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_12_21

G. Dharmshaktu, T. Ansari

引用次数: 0

Is exercise effective in attenuating side effects of androgen deprivation therapy among prostate cancer patients? 运动是否能有效减轻前列腺癌患者雄激素剥夺治疗的副作用?

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_47_20

C. Okechukwu

引用次数: 0

Evaluation of the role of itraconazole and posaconazole in viral infection as immunomodulatory drugs 伊曲康唑和泊沙康唑作为免疫调节药物在病毒感染中的作用评价

Matrix Science Medica Pub Date : 2021-10-01 DOI: 10.4103/mtsm.mtsm_34_20

Falah Obayes Al-Khikani

引用次数: 0

Envisaging conduction of periodic reviews to strengthen the preparedness and emergency response to coronavirus disease 2019 outbreak 设想开展定期审查，以加强对2019年冠状病毒病疫情的防范和应急响应

Matrix Science Medica Pub Date : 2021-07-01 DOI: 10.4103/MTSM.MTSM_42_20

S. Shrivastava, P. Shrivastava

引用次数: 0

Prospects and opinions in immunopathogenesis of COVID-19 COVID-19免疫发病机制的展望与看法

Matrix Science Medica Pub Date : 2021-07-01 DOI: 10.4103/MTSM.MTSM_40_20

Falah Obayes Al-Khikani

引用次数: 0

Sharp foreign bodies in laryngotracheobronchial airway of children: Our experiences at a tertiary care teaching hospital 儿童喉气管支气管尖锐异物:我们在三级教学医院的经验

Matrix Science Medica Pub Date : 2021-07-01 DOI: 10.4103/MTSM.MTSM_48_20

S. Swain, Nibi Shajahan

{"title":"Sharp foreign bodies in laryngotracheobronchial airway of children: Our experiences at a tertiary care teaching hospital","authors":"S. Swain, Nibi Shajahan","doi":"10.4103/MTSM.MTSM_48_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_48_20","url":null,"abstract":"Background: Sharp foreign bodies (FBs) are rarely found in the laryngotracheobronchial (LTB) tree which may cause threatening to the life. Objective: The aim of this study is to evaluate or study the clinical details of the inhaled sharp FBs and its management in children. Methods: This is a retrospective descriptive study done in between April 2015 and May 2020. There were 22 children with inhaled sharp FB in the airway enrolled in this study. The diagnosis was done from proper history taking, clinical examination, and the X-ray of the neck, chest, and abdomen of the children. All of them underwent rigid bronchoscopy with grasping forceps for the removal of these sharp FBs. Results: Out of the 22 children, 13 were boys (59.09%) and 9 were girls (40.90%). Out of 22 cases, 4 FBs were found in the proximal part of the airway and 18 were seen in distal airways. The most common clinical presentation was chocking sensation with cough. Conclusion: Early diagnosis and prompt rigid bronchoscopy are required for preventing inhalation of the sharp FB in the LTB. Proper education to the caregivers or parents is very helpful to prevent this critical clinical entity.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"1 1","pages":"45 - 49"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79499150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0