Matrix Science Medica最新文献_第3页

A comparative clinical study of Marham-e-raal and povidone-iodine 5% ointment in nonhealing ulcers 5%聚维酮碘软膏治疗溃疡不愈合的临床比较研究

Matrix Science Medica Pub Date : 2023-07-01 DOI: 10.4103/mtsm.mtsm_2_23

Waseem Ahmad, S. Alam, Suhail Y Sahibole

{"title":"A comparative clinical study of Marham-e-raal and povidone-iodine 5% ointment in nonhealing ulcers","authors":"Waseem Ahmad, S. Alam, Suhail Y Sahibole","doi":"10.4103/mtsm.mtsm_2_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_2_23","url":null,"abstract":"Introduction: Nonhealing ulcers are those that have not proceeded through timely and orderly reparation to produce anatomic and functional integrity. Povidone iodine is widely used ointment among physician and surgeons globally for wound dressings. In texts of Unani medicine literature, Marham-e-raal has been described as a potent ointment for gaining timely healing of wounds. The aim of this study is to compare the effects of povidone iodine and Marham-e-raal in nonhealing ulcers/chronic wounds. Methods: A randomized controlled study was carried out in the Department of Jarahat (Surgery) in National Institute of Unani Medicine, Bengaluru. A total of 45 subjects were included and randomized into Marham-e-raal and betadine dressing groups based on inclusion criteria. Dressing was done on daily basis and subjects were assessed on every 15 day from baseline to day 45 for primary outcomes (appearance of healthy granulation, epithelialization, and reduction in wound surface area) and secondary outcomes (decreases in tenderness score and depth of wound). Results: Nineteen out of 27 subjects in Marham-e-raal dressing group achieved complete healing as compared to one in povidone-iodine dressing group. There was significant reduction in wound surface area, median tenderness score and depth of wounds among subjects in Marham-e-raal dressing group at 0.05 level of significance. Conclusion: Marham-e-raal is an effective wound dressing and healing agent as compared to povidone-iodine ointment.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"47 1","pages":"66 - 70"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90798016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The pattern of Rh phenotype among voluntary blood donors – A single-center observation from North India 自愿献血者Rh表型的模式-来自北印度的单中心观察

Matrix Science Medica Pub Date : 2023-07-01 DOI: 10.4103/mtsm.mtsm_3_23

T. Pangtey, V. Satyawali, Deepika Jangpangi

{"title":"The pattern of Rh phenotype among voluntary blood donors – A single-center observation from North India","authors":"T. Pangtey, V. Satyawali, Deepika Jangpangi","doi":"10.4103/mtsm.mtsm_3_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_3_23","url":null,"abstract":"Background: Human blood is precious and its availability and requirement are important elements of a comprehensive health-care delivery. Healthy voluntary donors are key sources to maintain the supply of human blood, and due care is warranted to ensure that the right blood reaches the right patient. Blood donor screening is standard practice, and the knowledge of ABO and Rh phenotype study is important. Prevalence and pattern of Rh phenotypes in a particular area may be important for various functioning of any blood bank. Materials and Method: Various centers frequently showcase prevalence pattern of Rh phenotype at a specified centre or region. A similar study was undertaken from collected data of voluntary blood donors in our tertiary care center. Results: Out of 2000 donor samples, B, A, O, and AB were in the decreasing order of frequency with 33.3%, 29.6%, 25.7%, and 11.4%, respectively. The most common Rh antigens observed were e (97.1%), followed by D (93.8%), C (88.45%), c (51.05%), and E (18.45%). Out of eight phenotypes in D-positive donors, R1R1 (DCCee), R1r (DCcee), and R1R2 (DCcEe) were most frequently observed. In D-negative donors, rr (ddccee), r'r (ddCcee), and r'r' (CCddee) were the most common. Conclusion: The Rh phenotype pattern in our centre had diverse pattern and knowledge of this would guide further studies.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"31 1","pages":"62 - 65"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87354840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current treatment of Meniere's disease 目前对梅尼埃氏病的治疗

Matrix Science Medica Pub Date : 2023-01-01 DOI: 10.4103/mtsm.mtsm_8_22

S. Swain

{"title":"Current treatment of Meniere's disease","authors":"S. Swain","doi":"10.4103/mtsm.mtsm_8_22","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_8_22","url":null,"abstract":"Meniere's disease (MD) is a morbid inner ear disease that manifests disabling symptoms such as episodic vertigo, tinnitus, and fullness in the ear, for which patients seek immediate medical attention. The treatment of disabling vertigo of patients with MD remains controversial. Endolymphatic hydrops of the inner ear is presently considered the pathophysiology for explaining the underlying mechanisms of MD. There are many therapeutic options for MD, but no one is considered a highly effective modality for the cure of the MD. The primary purpose of the medical treatment of MD is to treat his or her symptoms rather than disease. Betahistine and diuretics are usually effective medical treatments for controlling vertigo in MD. However, there is no proven medical therapy for hearing loss or evolution of the disease in MD. There are several reports in favor of intratympanic use of aminoglycosides for the control of vertigo. Endolymphatic sac decompression is a surgical treatment option in the case of medically intractable MD. Vestibular neurectomy and labyrinthectomy are two important surgical techniques for the treatment of disabling vertigo of MD, but these surgical procedures are associated with relatively higher surgical morbidity. Recently, treatment with chemical labyrinthectomy/transtympanic gentamycin injection and endolymphatic sac decompression have gained favor for MD because they have less invasive techniques and are associated with fewer risks and side effects. The objective of this review article is to discuss current treatment options for MD to relieve disabling symptoms of MD and so improving the quality of life.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"64 1","pages":"1 - 6"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84485875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Role of topical intranasal corticosteroid for treatment of post-COVID olfactory dysfunction – Our experiences 局部鼻内皮质类固醇治疗新冠肺炎后嗅觉功能障碍的作用——我们的经验

Matrix Science Medica Pub Date : 2023-01-01 DOI: 10.4103/mtsm.mtsm_5_22

S. Swain, S. Panda, A. Sahu, S. Pani

{"title":"Role of topical intranasal corticosteroid for treatment of post-COVID olfactory dysfunction – Our experiences","authors":"S. Swain, S. Panda, A. Sahu, S. Pani","doi":"10.4103/mtsm.mtsm_5_22","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_5_22","url":null,"abstract":"Background: The coronavirus disease 2019 (COVID-19) is a highly contagious acute respiratory disease caused by a novel virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 infection presents with respiratory illness and even respiratory failure and death. Olfactory dysfunction is an important clinical manifestation that has an impact on quality of life. Objective: This study is designed to analyze the role of the topical nasal corticosteroid in post-COVID olfactory dysfunction. Materials and Methods: This is a prospective and descriptive study on 72 COVID-19 patients who were administered topical intranasal corticosteroids and olfactory training. All of them were diagnosed with COVID-19 infection by reverse transcription–polymerase chain reaction of the nasopharyngeal swab. The detailed clinical examination and treatment with intranasal corticosteroid and its outcome were analyzed. Results: In this study, 46 (63.88%) patients were male and 26 (36.11%) were female with a male-to-female ratio of 1.76:1. The age ranges from 18 to 58 years. There were 30 (41.66%) patients in the age range of 18–30 years and 42 (58.33%) patients in the age range of 31–58 years. Out of 72 patients, 11 (15.27%) patients recovered after 2 weeks, 34 (47.22%) patients recovered after 3 weeks, and 20 (27.77%) recovered after 4 weeks. Three patients lost to follow-up during the treatment period. Conclusion: COVID-19 infection is spreading quickly all the continents of the world. Olfactory dysfunction is an important symptom of the COVID-19 infection. Intranasal mometasone spray and olfactory training are useful treatment options for post-COVID olfactory dysfunction.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"58 1","pages":"16 - 19"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80025037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of morphological changes in hepatic parenchyma, bile ducts, and hepatic vasculature in patients with oriental cholangiohepatitis using ultrasonography 超声评价东方性胆管性肝炎患者肝实质、胆管和肝血管的形态学改变

Matrix Science Medica Pub Date : 2023-01-01 DOI: 10.4103/mtsm.mtsm_53_20

Mir Ahmad Kazime, O. ashraf, Mohd Ilyas

{"title":"Evaluation of morphological changes in hepatic parenchyma, bile ducts, and hepatic vasculature in patients with oriental cholangiohepatitis using ultrasonography","authors":"Mir Ahmad Kazime, O. ashraf, Mohd Ilyas","doi":"10.4103/mtsm.mtsm_53_20","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_53_20","url":null,"abstract":"Objective: The objective of this study is to study the morphological changes in hepatic parenchyma, to characterize the intra and extrahepatic ductal changes and to study the morphological changes in vasculature of the liver in patients with oriental cholangiohepatitits (OCH). Materials and Methods: All documented or newly diagnosed cases of OCH, referred to the department of radiodiagnosis and imaging from Departments of Surgical Gastroenterology and Medical Gastroenterology were evaluated by ultrasonography (USG) and color Doppler study. The dilatation of the intrahepatic as well as extra-hepatic ducts was noted. The morphological changes in the liver parenchyma as well as hepatic vasculature were studied. Results: USG showed calculi in 53 (98.1%) cases, ductal dilatation in 52 (96.3%), and worms within biliary ducts in 10 cases (18.5%). Among parenchymal changes, atrophy was seen in 9 cases (16.6%), space-occupying lesion was seen in seven cases (12.9%), and peri-portal echogenicity in 10 cases (18.5%). Significant association was found between atrophic segments and reduced/absent blood flow in the affected segmental portal venous branches. Conclusion: USG is the preferred primary examination. Further imaging depends on the USG findings, the patient's symptomatology, the clinical problems, and the intended mode of treatment. Advances in Knowledge: USG plays a pivotal role in the evaluation of oriental cholangiohepatitis in the low resource settings where higher modalities like MRI are not available, especially in the remote areas of developing countries, as it has high degree of accuracy in the diagnosis of OCH.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"38 1","pages":"7 - 11"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76343820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sphenoid sinus mucocele: Our experiences at a tertiary care teaching hospital of Eastern India 蝶窦黏液囊肿:我们在东印度三级护理教学医院的经验

Matrix Science Medica Pub Date : 2023-01-01 DOI: 10.4103/mtsm.mtsm_4_22

S. Swain, Prasenjit Baliarsingh

{"title":"Sphenoid sinus mucocele: Our experiences at a tertiary care teaching hospital of Eastern India","authors":"S. Swain, Prasenjit Baliarsingh","doi":"10.4103/mtsm.mtsm_4_22","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_4_22","url":null,"abstract":"Background: Sphenoid sinus mucocele is a benign expansile mucus-filled cystic lesion as a result of chronic obstruction of the sinus ostium. Because of its expansile, growth may affect nearby vital structures and result in the involvement of optic nerve and intracranial structures. Objective: This study aims to evaluate the details of patients with sphenoid sinus mucocele. Materials and Methods: In 5 years, we reported eight patients with mucocele in the sphenoid sinus. The detailed clinical presentations of these patients were documented. All the patients with sphenoid sinus mucocele were investigated with diagnostic nasal endoscopy and imaging such as computed tomography scan and magnetic resonance imaging (MRI) of the nose, paranasal sinuses, and brain. All underwent transnasal endoscopic transsphenoidal marsupialization of the mucocele in the sphenoid sinus. Results: There were eight patients diagnosed with sphenoid sinus mucocele. Out of eight patients, five (62.5%) were male and three (37.5%) were female with a male-to-female ratio of 1.66:1. The mean age of enrolled patients was 48.37 years. Out of eight patients with sphenoid sinus mucocele, three (37.5%) patients had allergic rhinitis, two (25%) patients had chronic sinusitis, and one (12.5%) patient had a history of radiation therapy for nasopharyngeal carcinoma. Conclusion: Sphenoid sinus mucocele is a rare clinical condition. In this study, headache was the most common symptom. Allergic rhinitis, sinusitis, and radiation to the head-and-neck region are important predisposing factors for causing sphenoid sinus mucocele. Orbital symptoms are indicators for prompt surgical intervention. Endoscopic sinus surgery is an effective and safe treatment option for sphenoid sinus mucocele.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"21 1","pages":"12 - 15"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81347200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidental finding of asymptomatic supracondylar process of the humerus: A case series 偶然发现的无症状肱骨髁上突:一个病例系列

Matrix Science Medica Pub Date : 2023-01-01 DOI: 10.4103/mtsm.mtsm_9_22

G. Dharmshaktu, Ishwar S. Dharmshaktu, N. Agarwal

引用次数: 0

Association of serum vascular endothelial growth factor levels with nephropathy and retinopathy in Type 2 diabetic patients 血清血管内皮生长因子水平与2型糖尿病患者肾病和视网膜病变的关系

Matrix Science Medica Pub Date : 2022-10-01 DOI: 10.4103/mtsm.mtsm_7_21

H. Hussin, W. Hussein, Sabah E. Ibrahim, Salih Almhdi, A. Saeed, AbdElkarim A. Abdrabo

{"title":"Association of serum vascular endothelial growth factor levels with nephropathy and retinopathy in Type 2 diabetic patients","authors":"H. Hussin, W. Hussein, Sabah E. Ibrahim, Salih Almhdi, A. Saeed, AbdElkarim A. Abdrabo","doi":"10.4103/mtsm.mtsm_7_21","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_7_21","url":null,"abstract":"Introduction: Vascular endothelial growth factor (VEGF), protein originally referred to as vascular permeability factor, maybe a signal protein produced by cells that stimulate the formation of blood vessels and a sub-family of growth factors. They are important signaling proteins engaged in both vasculogenesis and angiogenesis. It is a part of the system that restores the oxygen supply to tissues when blood circulation is insufficient like in hypoxic conditions. The serum concentration of VEGF is high in asthma and DM. The aim of this study to explore the relevance of VEGF level with the complication of diabetes mellitus (diabetic retinopathy [DR] and diabetic nephropathy (DN)). Methodology: Case–control study carried out in Khartoum–Sudan from August 2018 to August 2020. One hundred and four patients divided into four groups, 3 ml of blood were collected from each subject in sterile plain vacationer tube (3 ml) then was centrifuged, and the serum was stored at −20°C to measure VEGF level by using ELISA kits (E-EL-H0111, 96T). Results: We have confirmed previous observations of increased plasma VEGF Levels in patients with DR and DN. A total of 103 quality controls divided into four groups (diabetics with DR, diabetics with DN diabetics without DR or DN, and health individuals) were observed to determine the relationship between serum of VEGF levels and diabetes complication DR and DN. Conclusions: High level of VEGF plays a major role in the pathogenesis of DR and DN.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"38 1","pages":"101 - 105"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87042185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Correlation between use of the contraception and exclusive breastfeeding in Indonesia in 2017 (2017 Indonesian Demographic and Health Survey analysis data) 2017年印度尼西亚避孕药具使用与纯母乳喂养的相关性(2017年印度尼西亚人口与健康调查分析数据)

Matrix Science Medica Pub Date : 2022-10-01 DOI: 10.4103/mtsm.mtsm_20_21

F. Putri, Septa Katmawanti, Erianto Fanani

{"title":"Correlation between use of the contraception and exclusive breastfeeding in Indonesia in 2017 (2017 Indonesian Demographic and Health Survey analysis data)","authors":"F. Putri, Septa Katmawanti, Erianto Fanani","doi":"10.4103/mtsm.mtsm_20_21","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_20_21","url":null,"abstract":"Background: Breast milk is the first need for a newborn baby. Infants aged 0–6 months who are breastfed without any other food define exclusive breastfeeding. Exclusive breastfeeding can be influenced by several factors, one of which is contraception. Inappropriate use of contraception can affect exclusive breastfeeding. Aims: This study aimed to determine the correlation between contraceptive use and exclusive breastfeeding in Indonesia in 2017. Materials and Methods: The research design in this study was descriptive-analytic with a cross-sectional approach. This study examines the population of women of childbearing age who are married and have their last child aged 0–6 months with a total sample of 1891 people, with a sampling technique using total sampling. The data were taken from the results of the 2017 Indonesian Demographic and Health Survey. The data analysis of this study used the Chi-square statistical test. Result: The results of data analysis showed that 53% of women of childbearing age used contraception, and 47% of women of childbearing age did not use contraception. Meanwhile, 46% of women of childbearing age gave exclusive breastfeeding, and 54% of women of childbearing age did not give exclusive breastfeeding. The Chi-square test results showed a P = 0.000 (P < 0.05). Conclusions: Based on the study results, it can be concluded that there is a correlation between contraceptive use and exclusive breastfeeding in Indonesia in 2017.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"140 1","pages":"106 - 111"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77686764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Blistering distal dactylitis resembling a finger dipped in milk cream: An uncommon case report 水泡远端指炎类似于手指浸在牛奶奶油:一个罕见的病例报告

Matrix Science Medica Pub Date : 2022-10-01 DOI: 10.4103/mtsm.mtsm_7_22

Ishwar S. Dharmshaktu, N. Agarwal, G. Dharmshaktu

引用次数: 0