Forensic Chemistry最新文献_第5页

Degradation of immediate precursors of fentanyl and fentalogs 芬太尼和芬太尼前体的降解

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-22 DOI: 10.1016/j.forc.2024.100573

Raghu Venkatapathy , Ryan Kauchak , Jacob Botkins , Matthew L. Magnuson

{"title":"Degradation of immediate precursors of fentanyl and fentalogs","authors":"Raghu Venkatapathy , Ryan Kauchak , Jacob Botkins , Matthew L. Magnuson","doi":"10.1016/j.forc.2024.100573","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100573","url":null,"abstract":"<div><p>Remediation of clandestine laboratory and processing operations for fentanyl and its analogs (i.e., fentalogs) may involve application of oxidants, most commonly household hypochlorite bleach, to chemically degrade the fentanyl to enable disposition of the site. While the chemical degradation of fentanyl has been reported, the degradation of immediate precursors has not been. Chemical degradation of fentanyl and fentalogs can cause these immediate precursors to reform. The immediate precursors of fentanyl investigated here are norfentanyl and 4-ANNP, which are controlled substances, along with norcarfentanil, precursor for carfentanil and remifentanil. The 4-ANNP was degraded within minutes in chlorine bleach, somewhat faster than fentanyl itself, whereas norfentanyl and norcarfentanil showed apparent degradation half lives up to days. Also, degradation rates were reduced in the presence of common diluents, like cutting agents, with apparent half-lives of several weeks for fully dissolved solutions. When the fentalog was added as a powder, globules were observed which could indefinitely prevent contact between the chlorine and the contents of the globules, prolonging persistence unless the globules are mechanically or otherwise broken. Because of shared structural characteristics among fentalogs, such as presence of reactive nitrogen groups, the results of this study may be applicable to a wide array of fentalogs. This study may also help inform remediation and waste management strategies to provide not only effective remediation of contamination, but also reduce the possibility that wastes of controlled substances are handled inappropriately, e.g., leading to continued personnel exposure and/or reprocessing of controlled substances.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"39 ","pages":"Article 100573"},"PeriodicalIF":2.7,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140330677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a novel seized drug screening method utilizing DART-MS and used weigh paper 利用 DART-MS 和使用过的称重纸开发新型缉获药物筛选方法

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-20 DOI: 10.1016/j.forc.2024.100572

Alleigh N. Couch, J. Tyler Davidson

{"title":"Development of a novel seized drug screening method utilizing DART-MS and used weigh paper","authors":"Alleigh N. Couch, J. Tyler Davidson","doi":"10.1016/j.forc.2024.100572","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100572","url":null,"abstract":"<div><p>The conventional analytical scheme for seized drug analysis utilizes quick and cost-effective presumptive testing, such as color tests, followed by more discriminatory techniques, such as gas chromatography-mass spectrometry (GC–MS). Before the seized drug evidence is analyzed, the evidence is weighed using an appropriate weighing matrix and balance. Typically, the weighing matrix is discarded as chemical waste; however, the process of weighing the evidence leads to the deposition of drug residue onto the weighing matrix, which is then amenable to rapid analysis using ambient ionization approaches, such as direct analysis in real time mass spectrometry (DART-MS). This study demonstrates a DART-MS method for the rapid screening of seized drug evidence using filter paper and glassine paper weighing matrices commonly found in forensic laboratories. Validation experiments were performed using filter paper and glassine paper and compared to the results obtained using glass capillaries to assess the effectiveness of each weighing matrix. A total of 40 authentic samples, 20 filter papers and 20 glassine papers, were analyzed and the resulting spectra were searched using the National Institute of Standards and Technology (NIST) DART-MS Forensics Database and Data Interpretation Tool (DIT). When compared to the ground truth GC–MS results, the developed approach had a 90% correct identification rate, with all misidentifications being due to the presence of tablets rather than powder. The developed DART-MS screening method provides the seized drug community with a method to rapidly screen seized drug residue remaining from the weighing process and to improve the overall laboratory efficiency.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"39 ","pages":"Article 100572"},"PeriodicalIF":2.7,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the Cross-Contamination of explosive canine training aids during manufacturing and storage 爆炸性警犬训练器材在制造和储存过程中的交叉污染分析

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-19 DOI: 10.1016/j.forc.2024.100571

Kymeri Davis, John V. Goodpaster

{"title":"Analysis of the Cross-Contamination of explosive canine training aids during manufacturing and storage","authors":"Kymeri Davis, John V. Goodpaster","doi":"10.1016/j.forc.2024.100571","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100571","url":null,"abstract":"<div><p>Explosive detecting canines should be trained using real explosive materials that have minimal contamination by other explosive odors to ensure accurate identification of potential threats. Therefore, the potential for cross-contamination between training aids is of importance. There are various storage methods in use by canine handlers, such as plastic and cloth bags, but these can lead to cross-contamination between training aids during storage. Alternatively, odor-permeable membrane devices (OPMD) may store training aides and be used as a delivery device. OPMDs allow for volatile compounds from the training aids to be released during training while helping to prevent contaminants from entering the device. However, the amount of contamination in a training aid upon receipt from a vendor is outside the control of canine handlers. To test the initial cross-contamination levels of training aids, 11 explosive materials were ordered from three different vendors. A 1-gram sample of each was collected and analyzed using gas chromatography – mass spectrometry. In several cases, explosive materials that are commercially available already exhibit elevated levels of contamination. This indicates that training aids must be acquiring contamination during manufacturing and/or storage at the vendor facility. The cross-contamination of explosive canine training aids stored in OPMDs was further evaluated and compared to traditional storage methods by storing various combinations of storage containers with explosives and using activated charcoal strips to collect the volatile compounds. Only one type of storage container, a Velcro bag, showed evidence of contamination.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100571"},"PeriodicalIF":2.7,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial results from SEM-EDX and LA-ICP-MS chemical characterisation of barium titanate glass microspheres 钛酸钡玻璃微球的 SEM-EDX 和 LA-ICP-MS 化学特性分析的初步结果

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-17 DOI: 10.1016/j.forc.2024.100569

Thomas Scholz , Andreas Gärtner

引用次数: 0

Evaluating the strength of evidence of elemental profiling of polymers with LA-ICP-MS 用 LA-ICP-MS 评估聚合物元素分析的证据强度

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-17 DOI: 10.1016/j.forc.2024.100570

Mirjam de Bruin-Hoegée , Ruthmara Corzo , Peter D. Zoon , Peter Vergeer , Jorien Schoorl , Marcel J. van der Schans , Daan Noort , Arian C. van Asten

{"title":"Evaluating the strength of evidence of elemental profiling of polymers with LA-ICP-MS","authors":"Mirjam de Bruin-Hoegée , Ruthmara Corzo , Peter D. Zoon , Peter Vergeer , Jorien Schoorl , Marcel J. van der Schans , Daan Noort , Arian C. van Asten","doi":"10.1016/j.forc.2024.100570","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100570","url":null,"abstract":"<div><p>LA-ICP-MS is a powerful technique for obtaining a forensic elemental profile of polymer evidence materials. However, the lack of homogeneous polymer reference standards hampers database creation and reliably matching a sample to a specific source. Therefore, the current study aims to evaluate the strength of evidence of forensic polymer comparisons by applying a matrix-matched reference standard with known concentrations for elements of interest. Four datasets of tapes, electrical wires, tubing, and jerrycans were compiled using LA-ICP-MS. It was found that quantification with the new PVC standard or by simply using the response of one element as internal standard significantly reduced the between-run variation. For each class of polymeric materials, characteristic elements could be identified with PCA and LDA. To facilitate classification, elemental concentrations were found to be typical for specific colors and types of polymeric materials. For forensic comparison, a score-based Bayesian likelihood ratio model and the <em>t</em>-test overlap method performed better than the feature-based model and 4-sigma criterion, in terms of rates of misleading evidence. Normalization to <sup>13</sup>C and quantification with the PVC standard with and without prior normalization to <sup>13</sup>C slightly reduced rates of misleading evidence. The <em>t</em>-test method showed an overall average false inclusion rate of only 0.45% and a false exclusion rate of 2.4%. Maximum calibrated likelihood ratios of 0.014 to 1778 were found for the tape dataset. In conclusion, this study demonstrates that with the use of proper standards, quantitative elemental profiling with LA-ICP-MS is a promising tool for forensic classification and comparison of polymers.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100570"},"PeriodicalIF":2.7,"publicationDate":"2024-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468170924000225/pdfft?md5=5c5bcb8bb33403d98b3a31e531529f8b&pid=1-s2.0-S2468170924000225-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A naked-eye colorimetric assay for highly sensitive detection of CL-20 explosive 用于高灵敏度检测 CL-20 爆炸物的裸眼比色测定法

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-13 DOI: 10.1016/j.forc.2024.100568

Jian Tang , Jinxiang Wu , Yi He

{"title":"A naked-eye colorimetric assay for highly sensitive detection of CL-20 explosive","authors":"Jian Tang , Jinxiang Wu , Yi He","doi":"10.1016/j.forc.2024.100568","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100568","url":null,"abstract":"<div><p>2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) stands as the most energetically condensed explosive ever found, and poses a great security threat to humans. Here we report a naked-eye colorimetric assay for highly sensitive detection of CL-20. Through effective cascading of the hydrolysis process of CL-20 with nitrite-involved Griess reaction to yield a pink-colored azo product, the visual quantification of CL-20 is realized by taking advantage of corresponding colorimetric signals. Under optimal experimental conditions, the present colorimetric assay is successfully used for highly selective determination of CL-20 in deionized water and environmental water samples with a nanomolar sensitivity. The resulting limit of detection is much lower than conventional methods. Moreover, benefiting from the distinct color change of the detection solution, direct naked-eye semi-quantitative analysis of CL-20 is achieved with a threshold concentration of 1 μM. Such simple, cost-effective, selective, and highly sensitive visual colorimetric assay will have valuable applications in public safety, environmental monitoring, and other related fields.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100568"},"PeriodicalIF":2.7,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of performance rates on the elemental comparison of small and irregular glass fragments using µ-XRF and LIBS 利用 µ-XRF 和 LIBS 对小型和不规则玻璃碎片进行元素比较的性能评估

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-04 DOI: 10.1016/j.forc.2024.100567

Oriana Ovide , Ruthmara Corzo , Tatiana Trejos

{"title":"Assessment of performance rates on the elemental comparison of small and irregular glass fragments using µ-XRF and LIBS","authors":"Oriana Ovide , Ruthmara Corzo , Tatiana Trejos","doi":"10.1016/j.forc.2024.100567","DOIUrl":"10.1016/j.forc.2024.100567","url":null,"abstract":"<div><p>This study describes a systematic assessment of the performance rates when analyzing small and irregular glass fragments using micro-X-ray Fluorescence Spectrometry (µ-XRF) and Laser Induced Breakdown Spectroscopy (LIBS). One hundred glass fragments were collected from the inner and outer panes of a vehicle windshield to assess the false exclusion rates. Additionally, 100 glass fragments originating from different vehicle windshields were used to evaluate the discrimination capabilities. To compare the effects of fragment size on the performance rates, half of the collected fragments were small (longest length between 0.4 mm and < 1 mm, and thickness greater than 0.4 mm for LIBS and 0.1 mm for μ-XRF), and the other half were full-thickness fragments (2 mm and greater). The study shows that precision deteriorates for small/irregular fragments and comparison items must have a similar size, shape, and thickness to minimize error rates. Thus, comparisons between full-thickness and small/irregular fragments should be avoided, regardless of the analytical method. Although this general concept is well known for µ-XRF, this effect was not previously reported as a concern for LIBS. Moreover, this study provides new sampling and comparison recommendations when using modern silicon drift detectors (SDD) and reduced fragment size. Using a 3 s (3 %RSD) comparison interval reduces the false exclusion rates to < 12 % for µ-XRF, and to < 4 % for LIBS when using either a 3 s or 4 s (3 % RSD) criterion. At least 4 known fragments are recommended for full thickness fragments and 6 to 9 known fragments for the small/irregular comparisons.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100567"},"PeriodicalIF":2.7,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140074051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of bioluminescence assay to assess PCR carryover contamination in forensic DNA laboratories 应用生物发光检测法评估法医 DNA 实验室中的 PCR 携带污染

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-03-03 DOI: 10.1016/j.forc.2024.100566

Tetsuya Satoh , Yukinobu Kutsuwada , Shota Inokuchi , Takenori Ishida , Takeshi Ikeda , Ryuichi Hirota , Akio Kuroda , Kazutoshi Matsumura , Susumu Iwase

{"title":"Application of bioluminescence assay to assess PCR carryover contamination in forensic DNA laboratories","authors":"Tetsuya Satoh , Yukinobu Kutsuwada , Shota Inokuchi , Takenori Ishida , Takeshi Ikeda , Ryuichi Hirota , Akio Kuroda , Kazutoshi Matsumura , Susumu Iwase","doi":"10.1016/j.forc.2024.100566","DOIUrl":"https://doi.org/10.1016/j.forc.2024.100566","url":null,"abstract":"<div><p>In forensic DNA testing, PCR-based multilocus short tandem repeat (STR) profiling kits, which have high sensitivity and discriminatory power, are generally used to analyze autosomal and Y-chromosomal DNA profiles. Forensic DNA laboratories require strict quality control for DNA testing, as contamination during analyses leads to incorrect interpretation of DNA profiles. Here, we aimed to apply bioluminescence assay to detect and monitor residual PCR products on laboratory work area and equipment surfaces by targeting dATP in the PCR product and allelic ladder marker. Two commercially available bioluminescence assay kits (CheckLite HS Plus and UltraSnap™) were examined for their sensitivity after confirming their reactivity to dATP. In the assay using CheckLite HS Plus, the lower detectable sample volumes were calculated as 10 pl of PCR product of GlobalFiler and PowerPlex Fusion and 1 pl of PCR product of Yfiler Plus and the allelic ladder marker of GlobalFiler, whereas those in the assay using UltraSnap™ were calculated as 1 nl of PCR product and allelic ladder marker. The sample volumes of these kits were lower than those detected through electrophoresis. Thus, the sensitivity of these kits was sufficient to control PCR carryover contamination in the post-PCR areas. Furthermore, residual PCR products in the post-PCR areas were continuously monitored using a bioluminescence assay. The results showed that the bioluminescence values increased after handling PCR samples for electrophoresis and decreased after decontamination. Therefore, we concluded that the bioluminescence assay is useful for assessing PCR carryover contamination in post-PCR processes in forensic DNA laboratories.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100566"},"PeriodicalIF":2.7,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140031356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-based evaluation of the analytical schemes in ASTM E2329-17 Standard Practice for Identification of Seized Drugs for methamphetamine samples 对 ASTM E2329-17 标准做法中鉴定甲基苯丙胺样本中缉获毒品的分析方案进行循证评估

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-02-20 DOI: 10.1016/j.forc.2024.100560

Jeremy S. Triplett , Jeff Salyards , Sandra E. Rodriguez-Cruz , Jeremiah A. Morris , Darryl Creel , Joseph Zemmels , Megan Grabenauer

{"title":"Evidence-based evaluation of the analytical schemes in ASTM E2329-17 Standard Practice for Identification of Seized Drugs for methamphetamine samples","authors":"Jeremy S. Triplett , Jeff Salyards , Sandra E. Rodriguez-Cruz , Jeremiah A. Morris , Darryl Creel , Joseph Zemmels , Megan Grabenauer","doi":"10.1016/j.forc.2024.100560","DOIUrl":"10.1016/j.forc.2024.100560","url":null,"abstract":"<div><p>This study involved 71 forensic seized drug laboratories analyzing 65 total samples; 17 were ground-truth positive (i.e., they contained methamphetamine or cocaine); 48 were ground-truth negative (i.e., they did not contain methamphetamine or cocaine). The positive samples were prepared at several target-analyte concentrations and combined with common cutting agents. The negative samples were designed to be challenging and prepared to contain positional isomers of methamphetamine. Participants were sent two different sample sets. In the first, they were directed to only use a single, pre-selected analytical technique. In the second, they were directed to use a pre-selected analytical scheme consisting of multiple techniques in compliance with ASTM E2329-17. The results of the study showed good accuracy; sensitivity was 1.000 for all analytical schemes with 1-specificity (the false-positive rate) ranging from 0.000 to 0.250 when ASTM E2329-17 compliant analytical schemes were used. When only a single technique was used, accuracy was generally not as good; sensitivity ranged from 1.000 to 0.091, and 1-specificity ranged from 0.000 to 0.245.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100560"},"PeriodicalIF":2.7,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468170924000122/pdfft?md5=225346e9241489ad729d17978e8db108&pid=1-s2.0-S2468170924000122-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139923091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying VOCs from human remains detectable in water using comprehensive two-dimensional gas chromatography 利用综合二维气相色谱法识别水中可检测到的人体遗骸挥发性有机化合物

IF 2.7 3区医学

Forensic Chemistry Pub Date : 2024-02-20 DOI: 10.1016/j.forc.2024.100561

Jerika Ho , Darshil Patel , Wesley S. Burr , Clifford Samson , Shari L. Forbes

{"title":"Identifying VOCs from human remains detectable in water using comprehensive two-dimensional gas chromatography","authors":"Jerika Ho , Darshil Patel , Wesley S. Burr , Clifford Samson , Shari L. Forbes","doi":"10.1016/j.forc.2024.100561","DOIUrl":"10.1016/j.forc.2024.100561","url":null,"abstract":"<div><p>Understanding the volatile organic compounds (VOCs) emitted during human decomposition is crucial for search and recovery investigations and the development of improved human remains detection methods. However, the influence of water on human decomposition, and particularly the release of VOCs has received minimal attention compared to terrestrial scenarios. This knowledge gap is highly relevant for training human remains detection (HRD) dogs, as they are deployed in various scenarios, including land and water searches, yet little is known about the VOC profiles produced by human remains in these different environments.</p><p>The aim of this study was to establish a proof-of-concept methodology for collecting VOCs from submerged remains. Sorbent tubes and thin-film solid phase microextraction (TF-SPME) were utilized as neither have been studied for this purpose previously. Human remains were submerged in a tank of water. Headspace samples were collected by placing a metal hood over the tank to trap VOCs, which were then drawn into a sorbent tube via an air sampling pump. Water samples were collected for direct immersion utilizing TF-SPME membranes in the laboratory. Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry combined with thermal desorption was employed to analyze both sample types. The sorbent tube method identified 42 compounds while the TF-SPME technique identified 34 compounds. Overall, this study successfully demonstrated the feasibility of both VOC collection and analysis methods for human remains decomposition in water.</p></div>","PeriodicalId":324,"journal":{"name":"Forensic Chemistry","volume":"38 ","pages":"Article 100561"},"PeriodicalIF":2.7,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468170924000134/pdfft?md5=5d00b9169cac9aa2079730bdcde4d5d0&pid=1-s2.0-S2468170924000134-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139923088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0