Ege Tip Dergisi最新文献

筛选
英文 中文
Endometrium karsinomlarında immünohistokimyasal olarak yanlış-eşleşme onarım (MMR) protein ekspresyonunun prognostik parametreler ile ilişkisinin araştırılması 免疫血液校正法研究子宫内膜碳酸障碍(MMR)蛋白表达与预后参数的关系
Ege Tip Dergisi Pub Date : 2023-03-13 DOI: 10.19161/etd.1262422
Gürdeniz Serin, Pınar Savaş, N. Özdemir, O. Zekioğlu, L. Akman
{"title":"Endometrium karsinomlarında immünohistokimyasal olarak yanlış-eşleşme onarım (MMR) protein ekspresyonunun prognostik parametreler ile ilişkisinin araştırılması","authors":"Gürdeniz Serin, Pınar Savaş, N. Özdemir, O. Zekioğlu, L. Akman","doi":"10.19161/etd.1262422","DOIUrl":"https://doi.org/10.19161/etd.1262422","url":null,"abstract":"Amaç: Endometrium karsinomlarında son yıllardaki en önemli gelişme moleküler sınıflama olmuştur. Bu sınıflamada tümörler dört gruba ayrılmıştır: 1-POLE mutant grup, 2-Mikrosatellit instabil (MSİ) grup, 3-Yüksek kopya sayısı grubu (P53 mutasyonu), 4-Düşük kopya sayısı grubu. Bu gruplardan POLE ve MSİ grup daha iyi prognoza sahip olması ve immün-kontrol inhibitör tedavisinden fayda görebilme potansiyelleri ile öne çıkmaktadır. Çalışmamızda immünohistokimyasal (İHK) yöntemle MMR proteinlerinde (MLH-1, PMS-2, MSH-2, \u0000MSH-6) nükleer ekspresyon kaybı olan ve olmayan olguların prognostik paramaterelerinin karşılaştırılması amaçlanmıştır. \u0000Gereç ve Yöntem: Bölümümüzde 2017-2020 yılları arasında histerektomi materyalinde endometrium karsinomu tanısı almış ve İHK olarak MMR proteinlerinin değerlendirildiği 80 hasta çalışmaya \u0000alınmıştır. MMR kaybı olan ve olmayan olgular tümör boyutu, histolojik derece (HD), myometrial invazyon derinliği, lenfovasküler invazyon (LVİ) ve servikal tutulum açısından karşılaştırılmıştır. \u0000Bulgular: Olguların 37’sinde (%46,3) MMR proteinlerinin herhangi birinde kayıp mevcutken, 43’ünde (%53,7) kayıp izlenmemiştir. MMR protein nükleer ekspresyon kaybı açısından olgular \u0000karşılaştırıldığında, kayıp saptanan olguların %45,9'da (17/37), kayıp saptanmayan olguların ise %27,9'da (12/43) histolojik derece III'tü (p:0,03). Myometrium 1/2 dış invazyon, servikal stromal tutulum ve LVİ açısından iki grup arasında istatistiksel olarak anlamlı bir fark saptanmamıştır. \u0000Sonuç: Çalışmamızdaki olguların yaklaşık yarısında MMR proteinlerinin en az birinde kayıp saptanmıştır. En sık kayıp MLH-1 ve PMS-2 kaybı olarak ortaya çıkmıştır. MMR proteinlerinde nükleer \u0000ekspresyon kaybı izlenen olguların HD’si kayıp saptanmayan olgulara göre istatistiksel olarak anlamlı şekilde daha yüksek olma eğilimindedir.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47724283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acil servise kafa travması ile başvuran hastaların yönetiminde optik sinir kılıf çapı ölçümünün değerlendirilmesi 视神经间隙测量在颅脑损伤患者治疗中的评价
Ege Tip Dergisi Pub Date : 2023-03-13 DOI: 10.19161/etd.1262530
Özge Can, M. Ersel, S. Yalçinli, Funda Karbek Akarca
{"title":"Acil servise kafa travması ile başvuran hastaların yönetiminde optik sinir kılıf çapı ölçümünün değerlendirilmesi","authors":"Özge Can, M. Ersel, S. Yalçinli, Funda Karbek Akarca","doi":"10.19161/etd.1262530","DOIUrl":"https://doi.org/10.19161/etd.1262530","url":null,"abstract":"Amaç: Literatürde ultrasonografik olarak optik sinir kılıf çapı ölçümünde saptanan değerler, kafa içi basınç artışı ile ilişkilendirilmektedir. Kafa içi basıncı ölçümü yapılan hastalar kritik alan ya da yoğun bakım hastalarıdır. Hafif ya da orta şiddette kafa travmasında patolojiyi ya da operasyona gidişi öngörmede ultrasonografi ile optik sinir kılıf çapı ölçümünün etkisi değerlendirilmemiştir. Çalışmamızda kafa travması ile başvuran hastaların, ultrasonografi ile optik sinir kılıf çapı ölçüm değerlerini, kraniyal tomografi bulguları ve hastaların klinik sonlanımları ile karşılaştırmayı hedefledik. \u0000Gereç ve Yöntem: Prospektif kesitsel planlanan çalışmada acil servise başvuran kafa travmalı hastalar hafif, orta ve şiddetli beyin hasarı olarak değerlendirildi. Çalışmaya dahil edilen hastaların \u0000ultrasonografi ile optik sinir kılıf çapları ölçüldü. Bulgular hastaların sonlanımları ve kraniyal tomografi özellikleri ile karşılaştırıldı. \u0000Bulgular: Acil servise kafa travması ile başvuran 58 hastanın incelemesinde en sık hafif şiddette travmatik beyin hasarına rastlandı. Hastaların %51,7 (30)’sinde yatış ya da operasyon ihtiyacı vardı. \u0000Optik sinir kılıf çapı ölçümlerinin ortalaması sağda 4,96±1,02 mm (3,1-7,3) solda ise 4,92±1,02 mm (3,3-7,8) olarak bulunmuştur. Optik sinir kılıf çapı ölçüm değerlerinin 5 mm ve üzerinde saptanması \u0000hastaneye yatışı öngörmede istatistiksel olarak anlamlı olarak saptandı (p","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonlarıve potansiyel fonksionel etkileri
Ege Tip Dergisi Pub Date : 2023-03-13 DOI: 10.19161/etd.1262612
Bakiye GÖKER BAGCA, Sercan Göde, Goksel Turhal, Neslihan Özateş, Ali Veral, Cumhur Gündüz, Ç. Avci
{"title":"Nadir paranazal sinüs kanserlerinde yeni tanımlanan reseptör tirozin kinaz mutasyonları ve potansiyel fonksiyonel etkileri","authors":"Bakiye GÖKER BAGCA, Sercan Göde, Goksel Turhal, Neslihan Özateş, Ali Veral, Cumhur Gündüz, Ç. Avci","doi":"10.19161/etd.1262612","DOIUrl":"https://doi.org/10.19161/etd.1262612","url":null,"abstract":"Amaç: Paranazal sinüs kanserleri oldukça nadir görülen heterojen bir hastalık grubudur. Maksiler sinüs skuamoz hücreli karsinomu, paranazal sinüs kanserlerinin anatomik ve histolojik olarak en \u0000yaygın alt tipidir. Bu kanserin genetik profiline dair bilginin sınırlı olması, hastaların hedefli tedavi seçeneklerinden yararlanamamasına neden olmaktadır. Çalışmamızda bu nadir kanserdeki reseptör tirozin kinaz mutasyonlarının tanımlanması ve mutasyonların olası fonksiyonel etkilerinin tahmin edilmesi amaçlanmıştır. \u0000Gereç ve Yöntem: Bu amaçla 30 olgunun tümörüne ait FFPE dokulardan DNA izolasyonu gerçekleştirildi, olguların mutasyon profili yeni nesil sekanslama yöntemi ve biyoinformatik \u0000değerlendirme ile belirlendi. Belirlenen patojenik/ olası patojenik varyantların fonksiyonel etkileri farklı in silico araçlar yardımıyla tahminlendi. \u0000Bulgular: Olgularının tamamında en az bir adet patojenik/olası patojenik KIT, PDFGRA ve RETmutasyonu belirlendi. KIT geninin katalitik bölgesindeki mutasyonların kinaz aktivitesini arttıracağı \u0000tahmin edildi. PDFGRA genindeki p.P567P ve p.D1074D mutasyonları, 30 olgunun tamamında ve SRA veritabanından elde edilen normal dokulara ait okumaların tümünde belirlendi. \u0000Sonuç: Reseptör tirozin kinaz mutasyonlarının paranazal sinüs kanserlerinde de önemli rol oynayabileceğinin belirlenmiş olması özellikle artmış kinaz aktivitesini hedefleyen tedavi yaklaşımlarını \u0000bu olguların erişimine sunma potansiyeli taşıması bakımından oldukça önemlidir.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deformed bladder activity mimicking pelvic crossed ectopic kidney on Technetium-99m labelled dimercaptosuccinic acid renal cortical scintigraphy ~(99m)锝标记二巯基丁二酸肾皮质闪烁显像模拟骨盆交叉异位肾的变形膀胱活动
Ege Tip Dergisi Pub Date : 2023-03-13 DOI: 10.19161/etd.1262632
F. Tamer, B. Yazıcı, A. Oral, A. Akgün
{"title":"Deformed bladder activity mimicking pelvic crossed ectopic kidney on Technetium-99m labelled dimercaptosuccinic acid renal cortical scintigraphy","authors":"F. Tamer, B. Yazıcı, A. Oral, A. Akgün","doi":"10.19161/etd.1262632","DOIUrl":"https://doi.org/10.19161/etd.1262632","url":null,"abstract":"Technetium-99m dimercaptosuccinic acid (DMSA) scan was performed on a 32-year-old woman with \u0000abdominal pain. A normal functioning slightly ptotic right kidney was seen on planar images. There \u0000was no activity in the left renal region and a small fusiform activity was seen in the right pelvic area. \u0000Pelvic computed tomography (CT) axial images revealed pre-vesical pelvic abscess pushing the \u0000bladder posteriorly to the right side. On computed tomography images obtained after percutaneous \u0000drainage it was concluded that the activity in the right pelvic area on Technetium-99m DMSA scan was \u0000compatible with physiological activity in the bladder.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49657023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of hyperbaric oxygen therapy on the morphological characteristics and survival of MCF-7 breast cancer cells 高压氧治疗对MCF-7乳腺癌症细胞形态特征及存活率的影响
Ege Tip Dergisi Pub Date : 2022-12-27 DOI: 10.19161/etd.1235892
G. Yiğittürk, S. Ergözen, H. Elbe, Anıl Yücel, T. Çavuşoğlu, T. Baygar, Y. Uyanikgil
{"title":"Effects of hyperbaric oxygen therapy on the morphological characteristics and survival of MCF-7 breast cancer cells","authors":"G. Yiğittürk, S. Ergözen, H. Elbe, Anıl Yücel, T. Çavuşoğlu, T. Baygar, Y. Uyanikgil","doi":"10.19161/etd.1235892","DOIUrl":"https://doi.org/10.19161/etd.1235892","url":null,"abstract":"Aim: This study aims to determine the effects of hyperbaric oxygen therapy at different pressure values on cell morphology and cell survival in the MCF-7 breast cancer cell line.\u0000Materials and Methods: The experimental groups were formed by applying 100% oxygen to MCF-7 breast cancer cells at 1.5, 2, and 2.5 atmospheres for 2 hours. The control group did not receive treatment. At the end of the experiment, cell survival was investigated by CCK-8 analysis, cell shapes were determined by cresyl violet staining, and cell surface morphologies were determined by scanning electron microscope.\u0000Results: Cell viability was significantly reduced at atmospheric pressure of 1.5, 2, and 2.5 compared to the control group (p < 0.005). As pressure increased, the surface area of the cell decreased, nuclear condensation increased, and the cell borders became irregular. Cell membrane bleb and cell membrane porosity increased at 2 and 2.5 atmospheres.\u0000Conclusion: Hyperbaric oxygen therapy severely reduces the viability of MCF-7 breast cancer cells under increased pressure. It can induce apoptosis and change the shape and surface morphology of MCF-7 breast cancer cells. Although further studies are needed, our study supports the potential use of hyperbaric oxygen therapy in the treatment of breast cancer.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48858026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of lavender oil and ice applications used in episiotomy care on episiotomy pain 薰衣草精油和冰敷在会阴切开术护理中对会阴切开术疼痛的影响
Ege Tip Dergisi Pub Date : 2022-12-19 DOI: 10.19161/etd.1209135
Ayşe Emi̇nov, O. Kavlak, Elmin Emi̇nov, A. Ergenoğlu, I. Itil
{"title":"The effects of lavender oil and ice applications used in episiotomy care on episiotomy pain","authors":"Ayşe Emi̇nov, O. Kavlak, Elmin Emi̇nov, A. Ergenoğlu, I. Itil","doi":"10.19161/etd.1209135","DOIUrl":"https://doi.org/10.19161/etd.1209135","url":null,"abstract":"Aim: The present study investigates the effects of lavender oil and ice applications on episiotomy pain and wound healing. \u0000Materials and Methods: This study was organized as a semi-randomized controlled type of research. A total of 96 term pregnant women who gave birth in the delivery service of Nazilli State Hospital and underwent episiotomy at birth, had a Visual Analog Skala (VAS) value greater than 3 and agreed to participate in the study were included in the study. The patient information form, the Visual Analog Scale, and the REEDA Scale were used for data collection. The research data was analyzed using number, percentage, the chi-square test, the Kruskal Wallis test, the Mann-Whitney U test, One-Way Anova test, Tukey HD test, and the Wilcoxon Signed Ranks test.\u0000Results: The mean VAS values of the groups before the application were 7.90±0.92 for the lavender group, 8.29±1.03 for the ice group, and 8.00±1.00 for the control group. In addition, it was found that there was a statistically significant difference between the VAS values between the groups after the application (p<0.05), and the mean VAS values in the intervention groups decreased (Lavender group 6.84±1.08, ice group 5.70±1.53). While there was no statistically significant difference in the mean REEDA recovery scores between the groups before the application (p=0.912), there was a statistically significant difference in the REEDA recovery scores of the intervention groups and the control group after the application (p=0.000).\u0000Conclusion: According to the findings of the study, lavender oil and ice applications used after labor reduce perineal pain and accelerate wound healing.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributions from Turkey to the international emergency medicine literature during the COVID-19 pandemic: A bibliometric analysis COVID-19大流行期间土耳其对国际急诊医学文献的贡献:文献计量学分析
Ege Tip Dergisi Pub Date : 2022-12-19 DOI: 10.19161/etd.1209449
M. Çetin
{"title":"Contributions from Turkey to the international emergency medicine literature during the COVID-19 pandemic: A bibliometric analysis","authors":"M. Çetin","doi":"10.19161/etd.1209449","DOIUrl":"https://doi.org/10.19161/etd.1209449","url":null,"abstract":"Aim: The present study aimed to evaluate the bibliometric contributions made from Türkiye to the \u0000international scientific literature in the field of Emergency Medicine during the 2020-2021 period, which \u0000covered the COVID-19 pandemic period. \u0000Materials and Methods: The present study included a total of 872 studies in Emergency Medicine \u0000WoS Indexes between 2020-2021. The study data were retrieved from the Web of Science (WoS) \u0000database of Thomson Reuters – Clarivate Analytics, and the review included publications in the \u0000\"Emergency Medicine\" category from Turkey that spanned the pandemic period between the years \u00002019-2020.\u0000Results: 78.1% of the aforementioned studies were included in the Science Citation Index Expanded \u0000and 88.2% were original research papers. A total of 2930 researchers were involved in the 872 \u0000publications in the scope of the study. The average number of co-authors per publication was 5.2, \u0000where the average number of publications per author was 0.3. As regards the scope of the \u0000publications, the main topic was \"SARS-Cov-2 and pandemic\". The aforementioned main theme was \u0000associated with general emergency medicine practices, COVID-19 pneumonia, and high-mortality \u0000emergency cases.\u0000Conclusion: To the best of our knowledge, the present study is the first that investigated the studies \u0000from Turkey that contributed to the international literature in the field of emergency medicine during the \u0000pandemic period and provided valuable data reflecting the scientific productivity of the researchers, \u0000who continued their research in the field of emergency medicine, during the pandemic period.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatri pratiğinde transfontanel ultrasonografi 儿科医生经额超声检查
Ege Tip Dergisi Pub Date : 2022-12-19 DOI: 10.19161/etd.1209100
Hilâl Aydın, Selçuk Yazıcı, Emrah Akay, H. Balci, Işınsu Biçakcioğlu
{"title":"Pediatri pratiğinde transfontanel ultrasonografi","authors":"Hilâl Aydın, Selçuk Yazıcı, Emrah Akay, H. Balci, Işınsu Biçakcioğlu","doi":"10.19161/etd.1209100","DOIUrl":"https://doi.org/10.19161/etd.1209100","url":null,"abstract":"Amaç: Bu çalışmada, pediatri pratiğinde çeşitli endikasyonlar nedeni ile transfontanel ultrasonografi\u0000(TFUSG) istenilen hastaların tanısal profilinin ortaya çıkarılması hedeflenmiştir.\u0000Gereç ve Yöntem: Bu çalışmada, 01.08.2019-18.10.2021 tarihleri arasında, Balıkesir Üniversitesi Tıp\u0000Fakültesi çocuk sağlığı ve hastalıkları ile çocuk nöroloji polikliniklerinde çeşitli endikasyonlar ile\u0000transfontanel ultrasonografi istenilen 0-2 yaş arasındaki hastaların dosyaları retrospektif olarak\u0000incelendi. TFUSG bulguları normal/normalin varyasyonları ve anormal olarak ikiye ayrıldı.\u0000Bulgular: 77’si (%42,1) kız ve 106’sı (%57,9) erkek olmak üzere toplam 183 olgu çalışmaya dahil\u0000edildi. Olguların yaş ortalaması 119,55±134,52 gün (1-700 gün) idi. En sık TFUSG istem nedenleri;\u0000çeşitli etiyolojiler (n=79, %43,2), nöbet (n=37, %20,2), ve yenidoğan yoğun bakım ünitesine yatış\u0000öyküsü (n=23, %12,6) idi. 30 (%16,4) olguda TFUSG anormal olarak raporlandı. En sık anormal\u0000TFUSG bulguları; beyin omurilik sıvısı (BOS) mesafelerinde genişleme (n=8,%4,4), hidrosefali (n=7,\u0000%3,8), subaraknoid mesafede genişleme (n=5, %2,7) idi. TFUSG normal veya anormal olanlar\u0000arasında cinsiyet, gestasyon yaşına göre doğum ağırlığı ve baş çevresi açısından istatiksel olarak\u0000anlamlı farklılık saptandı (p=0,007, p=0,048, p=0,00).\u0000Sonuç: 0-2 yaş arası hastalarda TFUSG bulgularında cinsiyet, gestasyon yaşına göre doğum ağırlığı\u0000ve baş çevresi açısından anlamlı farklılık saptanması çalışmamızı öne çıkaran özelliktir ve üzerinde\u0000daha kapsamlı çalışılması gereken bir bulgudur.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47678369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of candida species and risk factors for invasive candidiasis 侵袭性念珠菌病的种类分布及危险因素
Ege Tip Dergisi Pub Date : 2022-12-19 DOI: 10.19161/etd.1209148
Ali Korulmaz, Mehmet Alakaya, A. Arslankoylu, Sadi Kaya, S. Erdoğan, Didem Ozgur, Z. F. Otağ
{"title":"Distribution of candida species and risk factors for invasive candidiasis","authors":"Ali Korulmaz, Mehmet Alakaya, A. Arslankoylu, Sadi Kaya, S. Erdoğan, Didem Ozgur, Z. F. Otağ","doi":"10.19161/etd.1209148","DOIUrl":"https://doi.org/10.19161/etd.1209148","url":null,"abstract":"Aim: The aim of this study was to investigate the Candida species isolated from the clinical samples of patients in the pediatric intensive care unit and to determine the risk factors for invasive candidiasis. \u0000Materials and Methods: Patients with Candida species detected in clinical samples between January 2013 and December 2018 were included in this study. The demographic characteristics of the patients, the use of broad-spectrum antibiotics and immunosuppressive drugs, underlying diseases, blood transfusions, history of surgical operations, whether there is bacterial growth with Candida species in the same clinical sample, parenteral nutrition and invasive interventions were retrospectively analyzed and their relationship with invasive candidiasis was investigated. \u0000Results: A total of 91 patients were included in the study. The mean age was 72.3 ± 70.1 months. Among the patients 48.4% had Candida albicans while 51.6% had non-albicans Candida. Candida parapsilosis (n = 18, 19.8%) and Candida tropicalis (n = 14, 15.4%) were the most common non-albicans Candida species. The most common antifungal treatment was fluconazole (n = 34, 59.6%). There was no statistically significant relationship between invasive candidiasis and the underlying disease, central venous and / or urinary catheter, broad-spectrum antibiotic, corticosteroid, gender and surgical operation (p> 0.05). On the other hand, there was a statistically significant relationship between invasive candidiasis and parenteral nutrition, blood transfusion and bacterial growth with Candida species in the same clinical sample (p <0.05). \u0000Conclusions: Non-albicans Candida species are more common than Candida albicans in the pediatric intensive care units. Candida parapsilosis is the most common among non-albicans Candida species. Parenteral nutrition, blood transfusion and bacterial growth with Candida species in the same clinical sample increased the risk of invasive candidiasis.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of healthcare-associated infections in general intensive care unit in Meram State Hospital 梅拉姆州立医院普通重症监护室卫生保健相关感染的评估
Ege Tip Dergisi Pub Date : 2022-12-19 DOI: 10.19161/etd.1209450
Barış Balasar, Ö. Uğur, E. Eroğlu
{"title":"Evaluation of healthcare-associated infections in general intensive care unit in Meram State Hospital","authors":"Barış Balasar, Ö. Uğur, E. Eroğlu","doi":"10.19161/etd.1209450","DOIUrl":"https://doi.org/10.19161/etd.1209450","url":null,"abstract":"Aim: Healthcare-associated infections are a major source of concern in all areas of hospitals, particularly in intensive care units. The goal of our study was to look at the current situation and evaluate the measures that can be taken based on the data obtained by examining the rates and factors of healthcare-associated infections in the general intensive care units of our hospital over a one-year period.\u0000Materials and Methods: Between January 2020 and December 2020, 665 patients who were followed up and treated in the general intensive care unit of Meram State Hospital were followed up in terms of healthcare-associated infections, and their outcomes were evaluated.\u0000Results: 5354 hospitalization days of 665 patients who were followed up in the general intensive care units for a year were evaluated, and it was determined that 53 of the patients developed healthcare-associated infections. Twenty-two (41.5%) of patients with healthcare-associated infections were female, while 31 (58.5%) were male. It was discovered that the patients' mean age was 71,7±14 (19-94). The infection rate was calculated to be 5.86 and the density to be 7.28. Furthermore, the rates of invasive device-associated nosocomial infection are as follows: 1.02 for central line-associated bloodstream infections, 0.56 for catheter-associated urinary tract infections, and 0 for ventilator-associated pneumonia.\u0000Conclusion: Healthcare-associated infections are a significant cause of mortality and morbidity in intensive care units. Due to the improvement in medical care and the increase in life expectancy in parallel with this, effective surveillance practices are of critical importance.","PeriodicalId":32499,"journal":{"name":"Ege Tip Dergisi","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67802433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信