{"title":"In Vitro Anthelmintic Activity of Papaya (Carica papaya L.) Seed Tea Againts Gastrointestinal Trematodes in Cattle","authors":"K. Solehah, G. Tresnani, I. S. Pratama","doi":"10.21082/bullittro.v33n2.2022.68-75","DOIUrl":"https://doi.org/10.21082/bullittro.v33n2.2022.68-75","url":null,"abstract":"The prevalence rate of trematodosis in cattle is increasing in Bali and Nusa Tenggara, affecting productivity, sale value, and medical expenses. Papaya seeds (Carica papaya L.) contained metabolite compounds that had the potential as an anthelmintic for cattle. This study aimed to determine the anthelmintic activity of papaya seed tea and the percentage of gastrointestinal trematodes (Paramphistomum spp.) mortality in cattle. Worms that were actively moving were divided into five groups and applied with some treatments: the negative control (0.9% (w/v) of NaCl solution); the positive control (10% (w/v) Albendazole); and three concentrations of papaya seed tea (2.5, 5, and 10% (w/v)). The death time of 100% Paramphistomum spp. for negative control occurred at the 300th minute, longer than the papaya seed tea treatment, which happened in the 180th minute at a concentration of 2.5% and 210th minutes at 5% and 10% (w/v). Time of death 100% of positive control treatment Albendazole 10% (w/v) was the fastest (30 minutes). The death time parameter of papaya seed tea at the three concentrations significantly differed from Albendazole 10% (w/v) (p<0.05). Therefore, papaya seed tea could potentially be used as an antitrematodal agent to control Paramphistomum spp. in cattle.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43564167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phytochemical Screening Extract of Canna edulis K. by Using Gass Chromatography Mass Spectrometry","authors":"Nadyatul Ilma Indah Savira, Siti Shofa Qulbi Assyifa, Meilia Putri Marditianingsih, Mumtahana Laili","doi":"10.21082/bullittro.v33n2.2022.61-67","DOIUrl":"https://doi.org/10.21082/bullittro.v33n2.2022.61-67","url":null,"abstract":"Canna edulis K. is a tuberous crop containing starch that is frequently consumed as food. Due to the phytochemical content of canna tubers, several studies have demonstrated the use of canna tuber as an antioxidant, anticancer, antibacterial, and hepatoprotective agent. This study aims to quantitatively determine the phytochemical content of distilled water extract and ethanol extract of canna tuber, as previous research has only provided qualitative results. Old-red canna tubers were extracted using maceration and freeze-drying techniques. Using Gas Chromatography-Mass Spectrometry (GC-MS), the extraction results with two different solvent types were analyzed. According to the GC-MS results, the ethanol extract represented 32 phytochemical compounds, more abundant than the distilled water extract (16 compounds). The terpenoid compound tetradecamethylcycloheptasiloxane can be extracted with both ethanol and distilled water solvents, whereas the polysaccharide compounds D-Mannitol, 2-Deoxy-D-ribose, and d-Mannose can only be extracted with ethanol solvent. The results of the phytochemical analysis of canna tuber extract are expected to be utilized as pharmaceuticals or alternative food ingredients.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43880650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Added Value of Local Organic Wastes to Develop Aromatic Plants in Agroforestry","authors":"Muhammad Syamil Hizbi, I. Mansur, Nfn Supriyanto","doi":"10.21082/bullittro.v33n1.2022.41-52","DOIUrl":"https://doi.org/10.21082/bullittro.v33n1.2022.41-52","url":null,"abstract":"An agroforestry system consisting of fast-growing aromatic plants, such as citronella grass (Cymbopogon nardus L.) and tree crops that produce aromatic substances, such as ylang-ylang (Cananga odorata (Lam.) Hook. f. & Thomson forma genuina), was an alternative to the sustainable agricultural system. The growth and oil production of citronella grass can be enhanced by fertilization and planting patterns. The effects of planting patterns of citronella grass and ylang-ylang and compost application from various organic wastes on plant growth, biomass weight, and citronellal and geraniol content of citronella grass were investigated in a field experiment. The experiment consisted of two factors: planting patterns and types of fertilizer. Planting patterns (main plot) consisted of two levels, with citronella grass planted between ylang-ylang rows (IR) and between and within ylang-ylang rows (IWR). Five levels of fertilizer types comprised the subplot: no fertilization (P0), bamboo leaf compost (P1), vetiver leaf compost (P2), dairy cow dung compost (P3), and inorganic fertilizer (P4). Compost made from dairy cow manure significantly increased leaf length, tiller count per plant, canopy width, and citronellal content. Furthermore, its application in the IWR pattern revealed the optimal interaction that significantly increased citronella grass canopy width 4 and 8 weeks after planting. This result indicated that local organic wastes greatly aided the development of aromatic plants in agroforestry.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46530205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Influence of Drying Method on the Anthocyanin Character of Duwet Fruit Qualitatively and Quantitatively","authors":"L. H. Hidayat, D. G. Wirasisya, H. Muliasari","doi":"10.21082/bullittro.v33n2.2022.53-60","DOIUrl":"https://doi.org/10.21082/bullittro.v33n2.2022.53-60","url":null,"abstract":"The fruit of duwet (Syzygium cumini L.) has anthocyanin compounds with some pharmacological effects. Several factors, such as the drying method, determined anthocyanin levels. This study aimed to compare the drying method's effect on anthocyanins' qualitative and quantitative characteristics in duwet fruit. The drying methods tested were (1) fresh fruit (without drying), (2) freeze drying, and (3) sun drying. The sample was macerated with 96% alcohol and 3% citric acid (6:1) and concentrated using a rotary evaporator. The extracts were then qualitatively analyzed with color and TLC tests. Anthocyanin levels were analyzed by the UV-Vis spectrophotometer. The red and green colors of each sample indicated the presence of anthocyanins. Rf values of 0.25; 0.375; 0.5 indicated anthocyanin type, which was cyanidin 3-ramnosil glucoside 5-glucoside, cyanidin 3-glucoside, and petunidin 3,7 diglucoside. The average anthocyanin content in the freeze-drying and sun-drying method were successively 305.406 mg.l-1 and 99.0244 mg.l-1. The freeze-drying method showed stronger color intensity and higher anthocyanin levels (p<0.05) than sun drying.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48626835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Haryudin, O. Rostiana, Molide Rizal, Idam Holid, Kanda Sukandi
{"title":"Uji Ketahanan Galur Jambu Mete Terhadap Hama Helopeltis sp. (Hemiptera: Miridae)","authors":"W. Haryudin, O. Rostiana, Molide Rizal, Idam Holid, Kanda Sukandi","doi":"10.21082/bullittro.v33n1.2022.31-40","DOIUrl":"https://doi.org/10.21082/bullittro.v33n1.2022.31-40","url":null,"abstract":"One of the causes of low cashew productivity in production centers is the attacks by pest, especially the mosquito bug Helopeltis sp. (Hemiptera: Miridae). Control efforts can be done by using the resistant varieties. The study was conducted at Cikampek Experimental Farm, from January–December 2018. This study aims to determine the level of resistance of crossbred cashew (F1) against Helopeltis sp. using the free-choice test method. The study was arranged in a Randomized Group Design and repeated 2 times. Total of 50 crossbred cashew strains propagated by grafting were placed in cages in a circular position. The number of plants in each cage was 23 strains. A total of 5 pairs adult of Helopeltis sp. that had been fed for 2 hours were introduced and placed in the center of the cage. The observation began 2 days after Helopeltis sp. infested which repeated every 3 days for 1 month or stopped if the insects died. Parameters observed included the number of eggs laid, number of eggs hatched, number of Helopeltis sp. perched, attack intensity, number of shoots, number of leaves grown and length of recovery period. The results showed that 23 strains were tolerant to Helopeltis sp., namely numbers: 2.1, 5.3, 6.4, 7.1, 7.3, 8.1, 9.1, 10.3, 11.4, 13.3, 13.4, 14.1, 15.1, 17.1, 18.1, 19.1, 19.3, 21.1, 21.3, 22.3, 22.4, 24.1, and 25.4. The attack intensity was 10-87.5 %. At the time of recovery, shoot growth reached 1-4 shoots and leave growth reached 2-11 leaves. The recovery period occurred for 10-14 days. The yield of the tolerant strains obtained required for further testing in the field.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":"25 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41276104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Simarmata, Selvia Naswita, Eem Masaenah, P. Simanjuntak
{"title":"Bioproduction of Antioxidant Chemical Compounds from Endophytic Bacteria of Red Betel Plants (Piper cf. fragile. Benth)","authors":"R. Simarmata, Selvia Naswita, Eem Masaenah, P. Simanjuntak","doi":"10.21082/bullittro.v33n1.2022.22-30","DOIUrl":"https://doi.org/10.21082/bullittro.v33n1.2022.22-30","url":null,"abstract":"Endophytic bacteria living in plant tissues can produce the same secondary metabolite compounds as their host plants. Endophytic bacteria obtained from the red betel plant (Piper cf. fragile Benth) have the potential to produce antioxidant compounds. This research aimed to select endophytic bacteria that had antioxidant activity derived from leaves, stems, and roots of red betel. Each isolate was fermented in NB (Nutrient Broth) medium for 24 hours. The fermentation results were separated between supernatant and biomass. The supernatant was extracted with ethyl acetate and then assayed for antioxidant activity qualitatively and quantitatively by free radical attenuation method using ABTS reagent (2,2-Azinobis(3-etilbenzatiazolin)-6-sulfonat acid). The results showed that, from 15 isolates of red betel endophytic bacteria, four isolates showed qualitative antioxidant activity. Isolates of SMB1 and SMD3.1 had IC50 values of 23.11 and 94.88 ppm, respectively (IC50 value of trolox as control was 4,041 ppm). The quantitative test results of the selected extract of SMB1 isolate analyzed with GC-MS (Gas Chromatography-Mass Spectrometry), allegedly contained 1,2-Benzenediccarboxylic acid, bis(2-ethylhexyl) ester compound with a similarity percentage of 93% and had strong antioxidant activity.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43666961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Novriza Sativa, I. Anggraeni, H. H. Nafi'ah, R. Pratama, Dadi Nurdiana
{"title":"Increasing the Germination Ability of Bidara (Ziziphus nummularia (brum.f.) Wight & Arn) Seeds Through Dormancy Breaking with Chemical Treatment","authors":"Novriza Sativa, I. Anggraeni, H. H. Nafi'ah, R. Pratama, Dadi Nurdiana","doi":"10.21082/bullittro.v32n2.2021.99-106","DOIUrl":"https://doi.org/10.21082/bullittro.v32n2.2021.99-106","url":null,"abstract":"<em>The wild jujube plant is a shrub originating from Southeast Asia, which has many benefits, one of which is a traditional medicinal plant. The population of wild jujube plants in Indonesia is still rarely found, even though this plant has many benefits from leaves, roots to stems. With the benefits of wild jujube plants and the community's needs, it is necessary to hold propagation. Jujube plants can massively use seeds but require 2-3 months to sprout in optimum media. This study aimed to determine the effect of dormancy breaking treatment in chemistry on the germination ability of wild jujube seeds. This research has been implemented from July to August 2021 in Pataruman Village Tarogong Kidul-Garut District. This study used a nonfactorial Randomized Block Design method with six treatments and four replications. The first treatment was KNO<sub>3</sub> concentration 0.5% (A), KNO<sub>3</sub> concentration 1.0% (B), KNO<sub>3</sub> concentration 1.5% (C), H<sub>2</sub>SO<sub>4</sub> concentration 25% (D), H<sub>2</sub>SO<sub>4</sub> concentration 50% (E), and H<sub>2</sub>SO<sub>4</sub> concentration 75% (F). The results showed that the H<sub>2</sub>SO<sub>4 </sub>treatment with 50% concentration affected parameters normal seedling (%), seeds did not grow (%), growth speed (%), vigour index (%), germinations length (cm), and root length (cm) than KNO<sub>3</sub> and another H<sub>2</sub>SO<sub>4 </sub>concentration. Consider corrosiveness H<sub>2</sub>SO<sub>4</sub>, mask, gloves, and lab coat needed when using it in an outdoor or acid room.</em>","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41452124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolation and In Vitro Potential Test of Phosphate Solubilizing Bacteria from Asiatic Pennywort (Centella asiatica L. Urban) Rhizosphere","authors":"A. Kartikawati, B. Fitriatin, T. Simarmata","doi":"10.21082/bullittro.v32n2.2021.86-98","DOIUrl":"https://doi.org/10.21082/bullittro.v32n2.2021.86-98","url":null,"abstract":"Asiatic pennywort (Centella asiatica), a potential medicinal plant, is widely grown in the highlands dominated by Andisols. Phosphorus deficiency is one of the most common cultivation constraints in Andisols soils. Applying phosphate-solubilizing bacteria is an alternative to overcome P nutrient deficiency in Andisol soil because it can dissolve insoluble phosphate into soluble phosphate and produce growth hormones for plants. The study aimed to obtain phosphate-solubilizing bacteria isolates from the Asiatic pennywort rhizosphere, which can also produce IAA hormones and phosphatase enzymes. Bacteria were isolated on Pikovskaya medium, which was specific as phosphate solvent. Parameters observed were phosphate solubilization index, gram stain test, colony morphology, phosphatase activity, and indole acetic acid (IAA) production. Based on the isolation result, 29 isolates were Gram-negative bacteria, and one was Gram-positive. Twenty-five bacterial isolates could dissolve P; 10 isolates had the highest P solubilization index, possessed phosphatase activity, and produced IAA. The phosphatase activity ranged from 2.153–2.272 µg.g-1.hour-1, and IAA production was between 3.668–7.385 ppm. Three bacterial isolates from the Asiatic Pennyworth rhizosphere LMP 3.11, LMP 1.11, and LMP 3.18 showed the ability to dissolve phosphate in vitro of 5.04-7.00 µg.g-1.hour-1 and generated IAA 6.611-7.385 ppm. However, the three isolated bacteria are still required to evaluate for their safety in plants (hypersensitivity test) and mammals (hemolysis test). Furthermore, they should be formulated and tested for potency on Asiatic pennyworth grown on Andisols.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48914625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dyah Carinae Yalapuspita, E. Mursyanti, Y. Hartini
{"title":"Formulation of Eyeshadow with Butterfly Pea Petal (Clitoria ternatea Linn.) Extract as Natural Coloring Agent","authors":"Dyah Carinae Yalapuspita, E. Mursyanti, Y. Hartini","doi":"10.21082/bullittro.v33n1.2022.1-10","DOIUrl":"https://doi.org/10.21082/bullittro.v33n1.2022.1-10","url":null,"abstract":"<em><span lang=\"EN-US\">The butterfly pea flower (</span></em><span lang=\"EN-US\">Clitoria ternatea </span><em><span lang=\"EN-US\">Linn.) has a blue pigment called ternatin, traditionally used as a food coloring. This study aimed to determine the proper method to extract butterfly pea petals, the optimum ratio of simplicia and solvent, the effect of irritation and allergy, and the stability of the eyeshadow. The research stages were determination and identification, simplicia making, extraction, phytochemical content identification, eyeshadow material preparation, primary irritation evaluation, stability, and hedonic test. Two extraction methods were decoction and maceration with three variants of simplicia and solvent ratios, </span></em><span lang=\"EN-US\">e.g.,</span><em><span lang=\"EN-US\"> 1:5, 1:10, and 1:20. The maceration method with a 1:20 ratio indicated the optimum combination for producing butterfly pea petals extract (16.5982 g). Moreover, eyeshadow with the addition of butterfly pea petal extract showed no indication of allergic and irritating effects. Therefore, the maceration method with a 1:5 ratio could be further developed. Furthermore, this method was more stable in terms of odor and color, possessed a longer shelf-life of 15 days at low temperature (-5°C), and had a high hedonic value compared to other methods. Thus, the eyeshadow formulation with butterfly pea petal extract as its natural dyes was potential to be developed as cosmetics.</span></em>","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47891449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Gel Formulation of Methanolic Extract of Leucaena leucocephala Leaves on Propionibacterium acnes and Staphylococcus epidermidis","authors":"B. R. Sidharta, Astri Malaha, E. Mursyanti","doi":"10.21082/bullittro.v32n2.2021.75-85","DOIUrl":"https://doi.org/10.21082/bullittro.v32n2.2021.75-85","url":null,"abstract":"<p><em>White lead tree (<em>Leucaena leucocephala</em>) leaf extract includes antibacterial phytochemical compounds such as lupeol and flavonoids.<em> </em>The study aimed to determine the antibacterial activity of white lead tree methanolic extract and gel formulation against acne-causing bacteria <em>Propionibacterium acnes</em> and <em>Staphylococcus epidermidis</em>, also the physical quality of the preparation. The treatments included a methanolic extract of the White lead tree and extract gel formulations. The study used a completely randomized design (CRD) with five replications. ANOVA analyzed data at a 95% confidence level (p < 0.05) by SPSS software. Gel formulations were used in five concentrations (3.12, 6.25, 12.50, 25.00 and 50.00 %). The antibacterial activity test utilized was the agar diffusion method. The results showed the white lead tree leaf extract contains flavonoids with TFC as much as 12.33 <span style=\"text-decoration: underline;\">+</span> 0.02 mgQE.g<sup>-1</sup>. The antibacterial activity test of white lead tree leaf extract at all concentrations showed the most effective antibacterial activity against S. <em>epidermidis</em> with a zone of inhibition of 2.17 cm<sup>2</sup>, with no inhibitory zone against <em>P</em>. <em>acnes</em>. The gel preparation extract at all concentrations had no inhibitory activity against <em>P</em>. <em>acnes</em>, but the gel formulations inhibit<em> </em>S. <em>epidermidis </em>effectively at 50.00 % concentrations with a zone of inhibitions 0.82<span style=\"text-decoration: underline;\">+</span>0.30 cm<sup>2</sup>. The gel quality parameters looked homogeneity for 28 days; ph and stickiness were matched to the National Standardization Agency of Indonesia (NSI); however, the dispersibility and viscosity were not matched to NSI. In conclusion, plant leaf methanolic extract demonstrated antibacterial activity against the acne-causing bacterium <em>S. epidermidis. </em>Further study is needed on the potential of white lead tree leaves as a natural anti-acne.</em></p>","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47957682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}