Buletin Penelitian Tanaman Rempah dan Obat最新文献_第2页

Multidemensional Scaling Benih Lada Bersertifikat di Provinsi Kalimantan Barat

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2022-08-04 DOI: 10.21082/bullittro.v32n2.2021.62-74

Aprillia Gorda, Eva Dolorosa, Nfn Radian

{"title":"Multidemensional Scaling Benih Lada Bersertifikat di Provinsi Kalimantan Barat","authors":"Aprillia Gorda, Eva Dolorosa, Nfn Radian","doi":"10.21082/bullittro.v32n2.2021.62-74","DOIUrl":"https://doi.org/10.21082/bullittro.v32n2.2021.62-74","url":null,"abstract":"West Kalimantan Province is one of Indonesia's seven largest pepper-producing provinces and was solicited to be a pioneer and advocate of the national pepper development program. This study aimed to analyze the sustainability status of certified pepper seedlings in West Kalimantan. The sustainability of the seeds system was analyzed using the multidimensional scaling (MDS) method in four districts with seed orchard and pepper seedlings producers: Bengkayang District, Sambas District, Sanggau District, and Sintang District. The research stages were an analysis of the sustainability status based on the dimensions of ecology, economy, socio-culture, technology, and infrastructure, as well as legal and institutional, followed by an MDS analysis of 50 attributes related to the sustainability index scale based on values ranging from 0–100. The ecological, socio-cultural, technological, and infrastructural dimensions were quite sustainable in the certified pepper seedlings supply system, while the economic, legal, and institutional dimensions were less sustainable. 34 out of 50 attributes were influential and sensitive to the sustainability status of certified pepper seedlings. The dominant attributes were drought/dry season (ecology), low awareness of farmers in using certified seeds (social-culture) related to low demand for certified pepper seedlings (economy), production planning and seed distribution (technology and infrastructure), and the necessity to cooperate with a research institution and seed orchard (legal and institutional). Therefore, special efforts were required from the local government to increase the pepper seedlings' availability and provide information on good pepper cultivation management to farmers and pepper seedlings managers.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41585650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Ukuran Partikel dan Rasio Bahan Terhadap Pelarut Air pada Distilasi Minyak Atsiri Temulawak

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2022-01-28 DOI: 10.21082/bullittro.v32n2.2021.52-61

E. Budiyati, Angga Fredo Nugroho, Ristiana Fauziati

{"title":"Pengaruh Ukuran Partikel dan Rasio Bahan Terhadap Pelarut Air pada Distilasi Minyak Atsiri Temulawak","authors":"E. Budiyati, Angga Fredo Nugroho, Ristiana Fauziati","doi":"10.21082/bullittro.v32n2.2021.52-61","DOIUrl":"https://doi.org/10.21082/bullittro.v32n2.2021.52-61","url":null,"abstract":"Javanese turmeric (Curcuma xanthorrhiza) essential oil is one of the curcuminoids sources that are widely used in the food and health industries. Temulawak oil extraction usually uses ethanol as a solvent which is relatively less safe for health. This study aimed to evaluate the effect of particle size and the ratio of materials to water solvents in the distillation process of Javanese turmeric essential oil. The experiment was conducted at the Chemical Engineering Research Laboratory, Muhammadiyah University, Surakarta. The treatments tested were the powder size (20, 40, 60, dan 140 mesh), the ratio of material to water solvent (w/v) consisted of 100:800, 150:750, 200:700, and a distillation time of 3 hours at a constant temperature of 100oC with an interval of distillation duration of 0.5; 1; 1.5; 2; 2.5; and 3 hours. The parameters observed were the essential oil quality: organoleptic, refractive index, pH, mass or volume of the oil produced, and curcuminoid compounds using the GC-MS method. The maximum yield of Javanese turmeric essential oil (18.01g) was obtained at a particle size of 140 mesh with a distillation duration of 1.5–2 hours, and the ratio of raw material to solvent 100:800 (g.ml-1). Based on the GCMS analysis, the highest components in the Javanese turmeric essential oil were α-curcumin (42.17%) and α-cedrene (11.14%). The results indicated that the distillation process of Javanese turmeric oil using water as a solvent can be used as an alternative to substitute ethanol as a solvent.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42202411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FORMULASI DAN UJI AKTIVITAS TONIK RAMBUT EKSTRAK ETANOL DAUN BIDARA (Ziziphus nummularia) PADA KELINCI 滋补作用的配制与试验

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2022-01-28 DOI: 10.21082/bullittro.v32n1.2021.40-51

Novriza Sativa, Nfn Noviyanti, Risha Amilia Pratiwi, Siti Hindun

{"title":"FORMULASI DAN UJI AKTIVITAS TONIK RAMBUT EKSTRAK ETANOL DAUN BIDARA (Ziziphus nummularia) PADA KELINCI","authors":"Novriza Sativa, Nfn Noviyanti, Risha Amilia Pratiwi, Siti Hindun","doi":"10.21082/bullittro.v32n1.2021.40-51","DOIUrl":"https://doi.org/10.21082/bullittro.v32n1.2021.40-51","url":null,"abstract":"Hair tonic is one of the cosmetic products for hair loss treatment that can be applied practically, absorbed easily by the scalp, and posseses no irritation effect. Various plant extracts are formulated to treat hair loss as an alternative to synthetic-based hair tonics which causing harmful side effects. Ziziphus nummularia is potential to treat hair loss due to its antiinflammatory and antioxidant activities, reducing the negative effects of oxidative stress on scalp’s papillae cell. However, there are limited information on hair tonic formulation and testing of bidara leaves extract on hair growth in mammals. This study aimed to determine the best hair tonic formula from bidara leaves etahnolic extract and to test its activity on hair growth of rabbits. The study was conducted at the Faculty of Mathematics and Natural Sciences Laboratory, Garut University, from March 2020 to March 2021. The treatments were hair tonic formulations from ethanolic extract of bidara leaves at 3%, 6%, and 12% concentrations; distilled water (negative control) and minoxidil (positive control) and repeated three times Parameters observed were hair tonic characteristics (odor, color, viscocity, homogeneity, pH), irritation effect and hair growth rate. The formulas of 3%, 6%, and 12% of bidara leaves ethanolic extract had uniform odor, color, viscosity, homogeneity, and pH. Furthermore, all three formulas were non-irritating to rabbit skin. The best formula was hair tonic with 3% ethanolic extract of bidara leaves which was stimulated rabbit’s hair growth up to 10.67 mm for 28 days and was better than control and 2% minoxidil.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43731086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Immunomodulation Effect of Kaempferia galanga Ethanolic Extract On In Vitro Lymphocyte Cell Proliferation 山奈乙醇提取物对体外淋巴细胞增殖的免疫调节作用

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2021-11-09 DOI: 10.21082/bullittro.v32n1.2021.31-39

D. Sugiartanti, E. Wiedosari

{"title":"Immunomodulation Effect of Kaempferia galanga Ethanolic Extract On In Vitro Lymphocyte Cell Proliferation","authors":"D. Sugiartanti, E. Wiedosari","doi":"10.21082/bullittro.v32n1.2021.31-39","DOIUrl":"https://doi.org/10.21082/bullittro.v32n1.2021.31-39","url":null,"abstract":"Kaempferia galanga L. is a traditional medicine with antitumor properties, as indicated by its immunomodulatory activities. This study aimed to determine the effect of K. galanga on lymphocyte cell proliferation activity as an indicator of immunomodulatory properties. This study was conducted at the Indonesian Research Center for Veterinary Science (February to April 2018). The immunomodulatory activity of the extract was evaluated with an in vitro splenocyte proliferation assay. The assay was based on cellular enzymatic synthesis to transform the XTT from formazan tetrazolium as an indicator. The K. galanga extract was obtained by 96% ethanol extraction. The test was conducted in an aseptic condition, consisted of five treatment groups with three replications each. Three groups of splenocyte cell culture, each with extract concentration of 2.5 µg.ml-1, 25 µg.ml-1, and 250 µg.ml-1, as well as a positive (Concanavalin A/Con A) and negative (cell only) control. The cell suspension (10x104 cells/ml) was distributed on 96-well plates and cultured following the treatment groups. The same five plates were made for five days of observation and retrieved daily by observing an Elisa reader at 450 nm. The extract of K. galanga at 2.5 µg.ml-1, 25 µg.ml-1, and 250 µg.ml-1 significantly (P <0.05) promoted splenocyte proliferation compared to control. Therefore, it was expected that K. galanga has a high potential to be used as immunomodulators. Hence, further investigations should be done to clarify the mechanisms of the immunomodulatory effect of K. galanga as an antitumor in vivo.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48865127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

FARMING PRODUCTION COSTS AND RELATIVE COMPETITIVENESS OF INDONESIAN BLACK AND WHITE PEPPERS 印尼黑椒和白椒的农业生产成本和相对竞争力

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2021-08-27 DOI: 10.21082/bullittro.v32n1.2021.10-22

E. R. Pribadi, Agus Wahyudi

{"title":"FARMING PRODUCTION COSTS AND RELATIVE COMPETITIVENESS OF INDONESIAN BLACK AND WHITE PEPPERS","authors":"E. R. Pribadi, Agus Wahyudi","doi":"10.21082/bullittro.v32n1.2021.10-22","DOIUrl":"https://doi.org/10.21082/bullittro.v32n1.2021.10-22","url":null,"abstract":"Indonesia is one of the major pepper (Piper nigrum L.) producer countries in the world. The main pepper products are distinguished into black and white pepper. Each region has a tradition to produce each of the products and influencing cultivation practices and cost structure. This research was aimed to analyze the cost of productions of black and white pepper and their relative competitiveness to the pepper price at the farm level with conventional and improved cultivation practices. The survey methods were used to obtain the primary data from respondents selected with the snowball sampling method. Lampung and Bangka Belitung Islands were chosen to represent the black and white peppers of smallholders, respectively. The result showed that the farms with conventional cultivation practices did not have sustainable relative competitiveness, indicating higher production costs than the lowest prices received in the long term. On the other hand, relative competitiveness was relatively better in farms that implemented improved cultivation practices. Therefore, to achieve sustainable relative competitiveness, pepper farms should apply improved cultivation practices. The relative competitiveness of white pepper was better than black pepper because the productivity of white pepper was higher even though the production cost was also a little bit higher than black pepper.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47243362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ISOLASI DAN IDENTIFIKASI SENYAWA ANTIOKSIDAN 2-ETILHEKSIL-4-METOKSISINAMAT DARI EKSTRAK BIJI ALPUKAT (Persea americana Mill.) 毕己提取物对抗氧化剂2-乙基己基-4-甲氧基水杨酸酯的同工酶及鉴定

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2021-08-06 DOI: 10.21082/bullittro.v32n1.2021.1-9

F. Rachman, E. Septiana, Rika Damayanti, N. Yadi, Y. Hapsari, S. Rahmawati, F. Izzati, Nfn Bustanussalam, P. Simanjuntak

{"title":"ISOLASI DAN IDENTIFIKASI SENYAWA ANTIOKSIDAN 2-ETILHEKSIL-4-METOKSISINAMAT DARI EKSTRAK BIJI ALPUKAT (Persea americana Mill.)","authors":"F. Rachman, E. Septiana, Rika Damayanti, N. Yadi, Y. Hapsari, S. Rahmawati, F. Izzati, Nfn Bustanussalam, P. Simanjuntak","doi":"10.21082/bullittro.v32n1.2021.1-9","DOIUrl":"https://doi.org/10.21082/bullittro.v32n1.2021.1-9","url":null,"abstract":"Avocado (Persea americana Mill.) is a plant widely found in tropical regions such as Indonesia. Currently, people only consume the avocado flesh and dispose of the seed. This study aimed to examine the antioxidant activity, isolate and identify the active antioxidant structure from avocado seed extracts. The trial was conducted from January to June 2021 at the Chemical Laboratory of Natural Substance, Research Center for Biotechnology, LIPI. The avocado fruit used in this research was obtained from Cibitung Central Market, Bekasi. The solvents used in the extraction were n-hexane, ethyl acetate, 96% ethanol, and water with multilevel extraction. Antioxidant activity was tested using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical method. The structure of the active compound was determined using UV-Vis spectrophotometry, Fourier Transformation Infrared Spectroscopy (FTIR), and GCMS. The 96% ethanol extract had the highest antioxidant activity with EtOH.4.3.1 isolate as the most active antioxidant isolate with IC50 23,07±1,63 μg.ml-1. The identification results of isolate EtOH.4.3.1 of avocado seed extract with UV-Vis spectrophotometry, FTIR, and GCMS indicated 2-Ethylhexyl-4-methoxycinnamate acting as an antioxidant. Further analysis with Nuclear Magnetic Resonance (NMR) spectrometry of protons and carbon is required to determine the number and position of protons and carbon in the chemical structure.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41988433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

KERAGAMAN GENETIK 64 AKSESI KUNYIT ASAL INDONESIA BERDASARKAN MARKA P450-BASED ANALOGUE (PBA)

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2020-12-29 DOI: 10.21082/bullittro.v31n2.2020.123-134

T. K. Putri, Putri Ardhya Anindita, Noladhi Wicaksana, Tarkus Suganda, Vergel Concibido, A. Karuniawan

{"title":"KERAGAMAN GENETIK 64 AKSESI KUNYIT ASAL INDONESIA BERDASARKAN MARKA P450-BASED ANALOGUE (PBA)","authors":"T. K. Putri, Putri Ardhya Anindita, Noladhi Wicaksana, Tarkus Suganda, Vergel Concibido, A. Karuniawan","doi":"10.21082/bullittro.v31n2.2020.123-134","DOIUrl":"https://doi.org/10.21082/bullittro.v31n2.2020.123-134","url":null,"abstract":"Turmeric is a rhizome producing plant with many utilization such as for consumption, medicine, and colorant industries. The development of superior turmeric varieties in Indonesia needs to be supported by genetic diversity information availability. Despite its potential, genetic diversity information of Indonesian turmeric has not been widely observed. A molecular marker is used to address genetic diversity information with the accurate result due to minimum environmental influences. PBA can detect the P450 gene as a functional marker, which is related to the synthesis of secondary metabolites in a wide genome area. Thus, it can be used as an alternative marker to identify genetic diversity. This research aimed to obtain genetic diversity information of 64 turmeric accessions using eight primer sets of P450-Based Analogue (PBA). The study was conducted in the Central Laboratory of Padjadjaran University from June 2019 to January 2020. Results showed that the full 133 bands were detected with a range of allele number 8 - 45 bands and an average of 22.3 bands per allele. PIC analysis showed six primer sets of PBA had high polymorphisms ranged from 0.90 to 0.98, hence categorized PBA as a highly informative marker. Cluster analysis divided 64 turmeric accessions into two main clusters based on a similarity index ranged from 0.01 to 0.83. The accession of CL-GTL01 origins from Gorontalo had a low similarity coefficient of 0.01 to the other 64 accessions cluster. On the other hand, CL-NTB01 dan CL-PPB01 had the highest similarity index of 0.83. Based on the PIC value, the total number of polymorphic bands, and genetic distance, it can be concluded that local Indonesian turmeric had wide diversity based on PBA marker.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91385947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Compatibility of Piper retrofractum Vahl. and Curcuma xanthorrhiza Roxb. Extracts for Controlling Helopeltis antonii Sign. 风笛花的兼容性。和姜黄Roxb。用于控制Helopeltis antonii标志的提取物。

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2020-12-29 DOI: 10.21082/bullittro.v31n2.2020.107-122

Nfn Rohimatun, Nfn Dadang, I. W. Winasa, S. Yuliani

{"title":"The Compatibility of Piper retrofractum Vahl. and Curcuma xanthorrhiza Roxb. Extracts for Controlling Helopeltis antonii Sign.","authors":"Nfn Rohimatun, Nfn Dadang, I. W. Winasa, S. Yuliani","doi":"10.21082/bullittro.v31n2.2020.107-122","DOIUrl":"https://doi.org/10.21082/bullittro.v31n2.2020.107-122","url":null,"abstract":"Plant extracts as a botanical insecticide can be used in either single or mixture forms. Mixed extracts have advantages: reducing dependence on one plant species, being the synergistic effect which can increase the effectiveness of formulas, and reducing the possibility of resistance emergence. This study aimed to obtain compatible and synergistic comparisons of P. retrofractum with C. xanthorrhiza extracts that effectively control the third instar nymph of Helopeltis antonii. The comparison of P. retrofractum and C. xanthorrhiza extracts were 4:1, 2:1, 1:1, 1:2, and 1:4 (w/w). The experiment was performed in a completely randomized design using the contact method. The LC50, LC90, and LC95 values were calculated using the PoloPlus Ver 1.0 Program. The mixture interaction was determined from the Combination Index value. The results showed that P. retrofractum extract was compatible and synergistic with C. xanthorrhiza extract at a ratio of 2:1 (w/w). These were the best combination shown by the lowest LC50, LC90, and LC95 values and showed consistently strong synergistic properties compared to other concentrations. The components of P. retrofractum may be responsible for the insecticidal properties are piperine; piperanine; piperidine; 3,4-Pyridinedimethanol,6-methyl; Piperidine,1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-,(Z,Z)-; and (2E,4E,12E)-1-(Piperidine-1-yl)octadeca-2,4,12—trien-1-one. The insecticidal activity of C. xanthorrhiza may associated with its content of xanthorrhizol, Ar-curcumene, β-curcumene, curzerene, germacrone, 7-zingiberene, caryophyllene, and β-bisabolol. A combination of these two plant extracts has the potential to be further developed as a botanical insecticide to control H. antonii.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43949982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

POTENSI EKSTRAK DAUN PALIASA (Kleinhovia hospita) SEBAGAI ANTI Plasmodium falciparum PALIASE（Kleinhovia hospita）抗恶性疟原虫提取物

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2020-12-21 DOI: 10.21082/bullittro.v31n2.2020.85-96

Mery Budiarti, Wahyu Jokopriyambodo

{"title":"POTENSI EKSTRAK DAUN PALIASA (Kleinhovia hospita) SEBAGAI ANTI Plasmodium falciparum","authors":"Mery Budiarti, Wahyu Jokopriyambodo","doi":"10.21082/bullittro.v31n2.2020.85-96","DOIUrl":"https://doi.org/10.21082/bullittro.v31n2.2020.85-96","url":null,"abstract":"Paliasa (Kleinhovia hospita) is known as a plant that has been used empirically for malaria treatment, especially in Eastern Indonesia. However, scientific publications regarding to the antiplasmodial activity of these natural resources are still limited. The aim of this study was to examine the potency of paliasa leaves as antiplasmodial against Plasmodium falciparum parasite. The procedure included sample and extract preparation, antiplasmodial in vitro activity testing on P. falciparum strain 3D7, and phytochemical screening using Thin Layer Chromatography (TLC). The extracts and fractions were prepared through maceration process for 72 hours with 96% ethanol, then continued with multilevel liquid-liquid partition using hexane, ethyl acetate and 96% methanol. Antiplasmodial in vitro testing showed that ethyl acetate (IC50 1.08 µg.ml-1) and hexane (IC50 1.24 µg.ml-1) fractions were include to the highly activity category. The research samples contained alkaloids, triterpenoids and steroids as the major compounds. The terpenoid alkaloid compound was a cycloartane triterpenoid alkaloid that had been isolated from paliasa leaves. Therefore, it is assumed that the leaf of palasia has a compound with antiplasmodial activity. However, more research needs to be done to determine the active compound and the antiplasmodial mechanisms involved","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67796201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KOPI ARABIKA (Coffea arabica L.) PADA EDEMA TIKUS 有效抗炎提取物ETANOL和复制阿拉伯咖啡（Coffea ARABICA L.）PADA EDEMA Scientifici

Buletin Penelitian Tanaman Rempah dan Obat Pub Date : 2020-12-21 DOI: 10.21082/bullittro.v31n2.2020.75-84

Desy Muliana Wenas, Lisana Sidqi Aliya, Nita Usikatul Janah

{"title":"AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KOPI ARABIKA (Coffea arabica L.) PADA EDEMA TIKUS","authors":"Desy Muliana Wenas, Lisana Sidqi Aliya, Nita Usikatul Janah","doi":"10.21082/bullittro.v31n2.2020.75-84","DOIUrl":"https://doi.org/10.21082/bullittro.v31n2.2020.75-84","url":null,"abstract":"The coffee leaf contains flavonoid compounds that are known as an antiinflammation agent. The study aimed to determine antiinflammatory activity of arabica coffee's leaf extract (Coffea arabica L.) against edema on white rat soles of carrageenan-induced rats. The research began with the maceration extraction of coffee leaf in 70% ethanol. The inflammation test was held by measuring the formation of edema using a plethysmometer. The dosages of arabica coffee leaf extract used were 60 mg.kg-1, 120 mg.kg-1, and 180 mg.kg-1 rat weight of white Sprague Dawley rat (Rattus norvegicus). The data were analyzed by Kruskal Wallis and Mann Whitney non-parametric tests. Phytochemical screening showed that arabica coffee leaf extract contained flavonoid, saponin, alkaloid, tannin and triterpenoids compound. The arabica coffee leaf extract showed the best antiinflammatory activity at the dose of 180 mg.kg-1 rat weight with 71.66% inhibition percentage at the 5th hour, which was better than the positive control (66.91% edema inhibition at the same hour). This result determined that the leaf extract of arabica coffee had antiinflammatory activity. However, it is necessary to study the acute and chronic toxicity and formulates the arabica coffee leaf extract as a pharmacy product.","PeriodicalId":32447,"journal":{"name":"Buletin Penelitian Tanaman Rempah dan Obat","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42808727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0