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Precision Radiation Oncology最新文献

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Precision Radiation Oncology Pub Date : 2022-03-01 DOI: 10.1002/pro6.1150
{"title":"Issue Information","authors":"","doi":"10.1002/pro6.1150","DOIUrl":"https://doi.org/10.1002/pro6.1150","url":null,"abstract":"","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44386011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A mathematical and dosimetric approach to validate auto‐contouring by Varian Smart segmentation for prostate cancer patients 一种数学和剂量测量方法，用于验证前列腺癌症患者瓦里安智能分割的自动轮廓
Precision Radiation Oncology Pub Date : 2022-03-01 DOI: 10.1002/pro6.1147
Sudipta Mandal, Shrikant N. Kale, R. Kinhikar
{"title":"A mathematical and dosimetric approach to validate auto‐contouring by Varian Smart segmentation for prostate cancer patients","authors":"Sudipta Mandal, Shrikant N. Kale, R. Kinhikar","doi":"10.1002/pro6.1147","DOIUrl":"https://doi.org/10.1002/pro6.1147","url":null,"abstract":"The aim of this study was to quantify the discrepancies in geometrical and dosimetric impacts (in volumetric modulated arc therapy) between manually segmented (MS) contours and smart segmentation (SS) auto‐contours (by Varian Eclipse Treatment Planning System SS v13.5) for prostate cancer patients.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":"46 - 58"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47506867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Investigation of the systemic inflammatory index as a predictor of downstaging in locally advanced rectal cancer patients with preoperative chemoradiation 全身性炎症指数作为局部晚期直肠癌术前放化疗患者降期预测因子的研究
Precision Radiation Oncology Pub Date : 2022-03-01 DOI: 10.1002/pro6.1145
Wen-Lu Zou, Rui Huang, Ya-Qin Zheng, Chao Liu, Jujie Sun, Yan-lai Sun, J. Yue
{"title":"Investigation of the systemic inflammatory index as a predictor of downstaging in locally advanced rectal cancer patients with preoperative chemoradiation","authors":"Wen-Lu Zou, Rui Huang, Ya-Qin Zheng, Chao Liu, Jujie Sun, Yan-lai Sun, J. Yue","doi":"10.1002/pro6.1145","DOIUrl":"https://doi.org/10.1002/pro6.1145","url":null,"abstract":"To find the correlations between blood systemic inflammatory biomarkers at three treatment time points and clinical effects of neoadjuvant chemoradiotherapy through a retrospective study.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":"32 - 38"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44541146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carbon ion radiotherapy in the management of non‐small cell lung cancer 碳离子放射治疗非小细胞肺癌癌症
Precision Radiation Oncology Pub Date : 2022-03-01 DOI: 10.1002/pro6.1146
D. Seneviratne, H. Ishikawa, J. Mao, Jingjing M Dougherty, A. Bush, Mathew Thomas, R. Manochakian, Y. Lou, D. Owen, T. Sio, J. Kirwan, S. Ko, B. Hoppe
{"title":"Carbon ion radiotherapy in the management of non‐small cell lung cancer","authors":"D. Seneviratne, H. Ishikawa, J. Mao, Jingjing M Dougherty, A. Bush, Mathew Thomas, R. Manochakian, Y. Lou, D. Owen, T. Sio, J. Kirwan, S. Ko, B. Hoppe","doi":"10.1002/pro6.1146","DOIUrl":"https://doi.org/10.1002/pro6.1146","url":null,"abstract":"Despite advancements in local‐regional and systemic therapies, non‐small cell cancer (NSCLC) remains a leading cause of death worldwide. Among those treated with standard‐of‐care modalities, 30–60% experience disease recurrence. Carbon ion radiotherapy (CIRT) is a form of densely ionizing radiotherapy with unique physical and biological advantages over traditional photon and proton modalities. CIRT is expected to have a superior biological impact on tumors, and is believed to be less impacted by the presence of tumor hypoxia or cell cycle state. It also shows highly conformal physical dose deposition due to reduced lateral scattering of the particles, limiting the radiation dose delivered to adjacent organs at risk. To implement CIRT as a viable option in the treatment of NSCLC, technical aspects of treatment delivery – including appropriate beam arrangements, dose calculation algorithms, radiobiological models, and methods of motion management – must be thoroughly investigated. Furthermore, randomized clinical trials comparing CIRT versus traditional radiation modalities must be performed to show the benefits and risks associated with this novel treatment modality. This review discusses the rationale for utilizing CIRT in NSCLC, available clinical data to date, and the potential for future investigations that may pave the path for improving outcomes in those diagnosed with NSCLC.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":"69 - 74"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46734434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Advances in MRI‐guided precision radiotherapy MRI引导下精确放疗的研究进展
Precision Radiation Oncology Pub Date : 2022-01-22 DOI: 10.1002/pro6.1143
Chenyang Liu, Mao Li, Haonan Xiao, Tian Li, Wen Li, Jiang Zhang, Xinzhi Teng, Jing Cai
{"title":"Advances in MRI‐guided precision radiotherapy","authors":"Chenyang Liu, Mao Li, Haonan Xiao, Tian Li, Wen Li, Jiang Zhang, Xinzhi Teng, Jing Cai","doi":"10.1002/pro6.1143","DOIUrl":"https://doi.org/10.1002/pro6.1143","url":null,"abstract":"Magnetic resonance imaging (MRI) is becoming increasingly important in precision radiotherapy owing to its excellent soft‐tissue contrast and versatile scan options. Many recent advances in MRI have been shown to be promising for MRI‐guided radiotherapy and for improved treatment outcomes. This paper summarizes these advances into six sections: MRI simulators, MRI‐linear accelerator hybrid machines, MRI‐only workflow, four‐dimensional MRI, MRI‐based radiomics, and magnetic resonance fingerprinting. These techniques can be implemented before, during, or after radiotherapy for various precision radiotherapy applications, such as tumor delineation, tumor motion management, treatment adaptation, and clinical decision making. For each of these techniques, this paper describes its technical details and discusses its clinical benefits and challenges.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":"75 - 84"},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42764560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
FLASH radiotherapy: Research process from basic experimentation to clinical application FLASH放射治疗：从基础实验到临床应用的研究过程
Precision Radiation Oncology Pub Date : 2021-12-01 DOI: 10.1002/pro6.1140
Xiaohui Wang, Hui Luo, Xiao-li Zheng, H. Ge
{"title":"FLASH radiotherapy: Research process from basic experimentation to clinical application","authors":"Xiaohui Wang, Hui Luo, Xiao-li Zheng, H. Ge","doi":"10.1002/pro6.1140","DOIUrl":"https://doi.org/10.1002/pro6.1140","url":null,"abstract":"FLASH radiotherapy (FLASH‐RT) has gained attention as an ultra‐high dose rate RT in recent years. This treatment significantly shortens the time of RT and reduces the influence of tumor movement caused by breathing or other factors. In addition, it spares the surrounding normal tissues and organs while ensuring the anti‐tumor effect. With the efforts of scientific researchers and clinical staff, the FLASH effect has been successfully induced in electron, photon, and proton irradiation. Preliminary research has been carried out to explore its related mechanism. However, this has not yet been fully determined, although oxygen depletion was the proposed primary mechanism discovered. Due to the development of immunotherapy, studies on the involvement of the immune system in the FLASH effect have begun to attract attention. This study reviewed published experimental results to analyze and summarize the feasibility of FLASH‐RT widely used in clinical practice, and whether it could be combined with immune checkpoint inhibitors to guide therapy.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"5 1","pages":"259 - 266"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43450829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Proton beam radiation therapy treatment for head and neck cancer 质子束放射治疗头颈部癌症
Precision Radiation Oncology Pub Date : 2021-12-01 DOI: 10.1002/pro6.1135
N. Mohamed, Anna Lee, N. Lee
{"title":"Proton beam radiation therapy treatment for head and neck cancer","authors":"N. Mohamed, Anna Lee, N. Lee","doi":"10.1002/pro6.1135","DOIUrl":"https://doi.org/10.1002/pro6.1135","url":null,"abstract":"Proton beam therapy has gained popularity over recent years. This is likely due to improved affordability; that is, lower cost, and increasing reports on excellent patient‐reported outcomes. Protons’ physical properties provide dosimetric advantages over photon therapy due to the unique ability to have little‐to‐no “exit” dose, potentially translating to reduced toxicities and improved patient quality of life. The increased delivery of proton beam therapy to treat numerous head and neck cancers, including oropharynx, nasopharynx, sinonasal, in the re‐irradiation setting, and unilateral malignancies, has led to more studies elucidating the clinical risks and benefits. In this review, we aim to summarize the recent literature on proton beam therapy utilization in head and neck cancer. In addition, we discuss the process of treatment and planning, clinical treatment toxicities and outcomes, limitations, and future directions.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"6 1","pages":"59 - 68"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42056989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Issue Information 问题信息
Precision Radiation Oncology Pub Date : 2021-12-01 DOI: 10.1002/pro6.1142
{"title":"Issue Information","authors":"","doi":"10.1002/pro6.1142","DOIUrl":"https://doi.org/10.1002/pro6.1142","url":null,"abstract":"","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46632589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of lymph nodes metastasis in hypopharyngeal squamous cell carcinoma based on contrast‐enhanced computed tomography imaging 下咽鳞状细胞癌淋巴结转移的计算机断层造影分析
Precision Radiation Oncology Pub Date : 2021-12-01 DOI: 10.1002/pro6.1137
Dongqing Wang, Shuguang Zhang, Jin Xu, Limin Zhai, Baosheng Li
{"title":"Analysis of lymph nodes metastasis in hypopharyngeal squamous cell carcinoma based on contrast‐enhanced computed tomography imaging","authors":"Dongqing Wang, Shuguang Zhang, Jin Xu, Limin Zhai, Baosheng Li","doi":"10.1002/pro6.1137","DOIUrl":"https://doi.org/10.1002/pro6.1137","url":null,"abstract":"To investigate the frequency, distribution, and potential factors of lymphatic metastasis at each nodal level, and stratify the risk of lymph node metastasis in hypopharyngeal squamous cell carcinoma based on computed tomography.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"5 1","pages":"237 - 243"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49004381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compatibility assessment of Varian and Elekta robotic couch‐assisted six‐dimensional patient positioning correction systems with external independent imaging modalities Varian和Elekta机器人沙发辅助六维患者定位矫正系统与外部独立成像模式的兼容性评估
Precision Radiation Oncology Pub Date : 2021-12-01 DOI: 10.1002/pro6.1136
B. Sarkar, T. Ganesh, A. Munshi, A. Manikandan, Suresh Choudhari, K. Jassal, B. Mohanti, A. Pradhan
{"title":"Compatibility assessment of Varian and Elekta robotic couch‐assisted six‐dimensional patient positioning correction systems with external independent imaging modalities","authors":"B. Sarkar, T. Ganesh, A. Munshi, A. Manikandan, Suresh Choudhari, K. Jassal, B. Mohanti, A. Pradhan","doi":"10.1002/pro6.1136","DOIUrl":"https://doi.org/10.1002/pro6.1136","url":null,"abstract":"This study aimed to evaluate the compatibility of robotic couch‐assisted six‐dimensional (6D) patient positioning systems with gantry‐mounted and in‐room independent imaging modalities in two different accelerators.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":"5 1","pages":"244 - 250"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41369705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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