Food Research International最新文献_第9页

Ultrasound-integrated biofabrication of aligned piscine muscle tissue 超声整合鱼类肌肉组织的生物制造

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-03 DOI: 10.1016/j.foodres.2026.118580

Ruihao Niu , Enbo Xu , Yong Deng , Qihe Chen , Jun Chen , Donghong Liu

{"title":"Ultrasound-integrated biofabrication of aligned piscine muscle tissue","authors":"Ruihao Niu , Enbo Xu , Yong Deng , Qihe Chen , Jun Chen , Donghong Liu","doi":"10.1016/j.foodres.2026.118580","DOIUrl":"10.1016/j.foodres.2026.118580","url":null,"abstract":"<div><div>The directional alignment of highly mature muscle fibers is a crucial hallmark of successful muscle tissue regeneration in vitro, both in regenerative medicine and cultured meat. While 3D bioprinting enables precise fabrication of tissue architecture, it inherently lacks the capacity to control the spatial distribution and growth trajectories of cells embedded within the bioink. Here, we integrated ultrasound with 3D bioprinting to leverage its precision control capabilities for engineering highly aligned cellular organization and induce muscle fiber formation. Both computational simulations and experimental validation confirmed that exposure to 4000 kHz ultrasonic frequency yielded distinct cell alignment, concomitant with an enhanced proliferation rate. Intermittent low-intensity ultrasound (LIUS) stimulation effectively activated the mechanosensitive Piezo1 channels in piscine satellite cells (PSCs), promoting Ca<sup>2+</sup> influx. Ca<sup>2+</sup> activates ERK5 in the downstream MAPK pathway, which up-regulates Myogenin and MHC, and finally promotes PSCs differentiation and fusion into myotubes. This non-invasive ultrasound physical stimulation method has great potential for application in the construction of edible muscle tissue.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118580"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ILA-producing bifidobacterium bifidum ameliorates chronic kidney disease via AHR signaling by modulating the gut-kidney axis 产生ila的两歧双歧杆菌通过调节肠肾轴通过AHR信号改善慢性肾脏疾病

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-07 DOI: 10.1016/j.foodres.2026.118638

Qinglian Hua , Yang Meng , Jinpeng Hu , Yanchen Wei , Huaxi Yi , Xi Liang , Lanwei Zhang , Zhe Zhang

{"title":"ILA-producing bifidobacterium bifidum ameliorates chronic kidney disease via AHR signaling by modulating the gut-kidney axis","authors":"Qinglian Hua , Yang Meng , Jinpeng Hu , Yanchen Wei , Huaxi Yi , Xi Liang , Lanwei Zhang , Zhe Zhang","doi":"10.1016/j.foodres.2026.118638","DOIUrl":"10.1016/j.foodres.2026.118638","url":null,"abstract":"<div><div>Chronic kidney disease (CKD) is associated with gut microbiota dysbiosis and disruption of the gut-kidney axis, making probiotics—which can modulate host metabolism and the gut microbiome—a highly promising intervention strategy. Building on this premise, this study used High-Performance Liquid Chromatography (HPLC) to screen 39 candidate strains and successfully isolate two high indole-3-lactic acid (ILA)-producing strains of <em>Bifidobacterium bifidum</em>: FL228.1 and ZL.1. Whole-genome sequencing subsequently confirmed that both strains possess the aromatic lactate dehydrogenase (Aldh) gene, which is essential for ILA biosynthesis. The strains were then evaluated in an adenine-induced CKD mouse model. ZL.1 exhibited pronounced efficacy: it not only improved renal injury, restored gut barrier function, and corrected dysbiosis, as evidenced by an increased relative abundance of <em>Muribaculaceae</em> and a decreased abundance of <em>Dubosiella</em>, but also significantly elevated the level of the key metabolite ILA. In-depth mechanistic analysis revealed that ILA exerts its effects by activating the aryl hydrocarbon receptor (AHR) signaling pathway, which in turn inhibits NLRP3 inflammasome activation, thereby achieving the dual benefit of mitigating intestinal inflammation and alleviating renal fibrosis. Targeted metabolomics analysis supported the conclusion that high ILA production is a critical characteristic for <em>B. bifidum</em>'s modulation of the gut-kidney axis. In contrast, the FL228.1 strain showed moderate effects, with its specific mechanism remaining unclear. In conclusion, our study suggests that ILA-producing <em>B. bifidum</em> may ameliorate CKD by regulating the gut-kidney axis via ILA and AHR signaling. This indicates a potential probiotic strategy targeting tryptophan metabolism for CKD.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118638"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CRISPR/Cas12a and fork-shaped probe enhance LAMP–LFT integration for equipment-free detection of Listeria monocytogenes CRISPR/Cas12a和叉形探针增强LAMP-LFT整合，实现单核增生李斯特菌的无设备检测

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-03 DOI: 10.1016/j.foodres.2026.118592

Irina V. Safenkova , Maria V. Kamionskaya , Tatyana S. Serchenya , Oleg V. Sviridov , Boris B. Dzantiev , Anatoly V. Zherdev

{"title":"CRISPR/Cas12a and fork-shaped probe enhance LAMP–LFT integration for equipment-free detection of Listeria monocytogenes","authors":"Irina V. Safenkova , Maria V. Kamionskaya , Tatyana S. Serchenya , Oleg V. Sviridov , Boris B. Dzantiev , Anatoly V. Zherdev","doi":"10.1016/j.foodres.2026.118592","DOIUrl":"10.1016/j.foodres.2026.118592","url":null,"abstract":"<div><div><em>Listeria monocytogenes</em> is an important foodborne pathogen associated with high mortality rates, especially among vulnerable populations, and therefore requires diagnostic methods that are not only highly sensitive and rapid but also suitable for use in resource-limited settings. In this study, we developed an isothermal amplification assay integrated with a lateral flow test (LFT) for reliable detection of <em>L.</em> <em>monocytogenes</em>. Two assay formats were designed and compared: (1) loop-mediated isothermal amplification (LAMP) with LFT detection of fluorescein- and biotin-labeled amplicons, and (2) LAMP combined with CRISPR/Cas12a, using LFT to detect a cleaved fork-shaped enhanced probe labeled with three fluoresceins. Both LFT formats utilized a common conjugate of gold nanoparticles and anti-fluorescein antibodies (anti-FAM), but differed in the test zone immobilization strategy: streptavidin for LAMP, and anti-FAM for LAMP–CRISPR/Cas12a. Among 12 tested (primer – label) combinations, the most effective was identified, but the sensitivity of the LAMP–LFT format was limited by high signal variability. In contrast, the LAMP–CRISPR/Cas12a assay, targeting LAMP amplicons with guide RNA, achieved a detection limit of 0.9 copies/reaction—representing > 20,000-fold improvement in detectable DNA concentration compared with LAMP–LFT—and comparable to fluorescence-based detection techniques. The LAMP–CRISPR/Cas12a–LFT assay was first reported to detect <em>L.</em> <em>monocytogenes</em> cells following thermal lysis (10 min at 95 °C), with a single-cell detection limit (0.2 cells/reaction in buffer, 1 cells/reaction in spiked milk) and an analysis time of 80 min. These results demonstrate the potential of the approach for sensitive, equipment-free detection of foodborne pathogens in complex food matrices.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118592"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valorization of saline byproducts: Development of composite films from waste salted egg white and plant extracts 盐副产物的增值：用废咸蛋清和植物提取物制备复合膜

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-04 DOI: 10.1016/j.foodres.2026.118555

Meiling Xu , Yajie Chang , Xuying Wang , Shiwen Xu , Yaotong Liu , Yanqu Ma

引用次数: 0

The role of mycobiome in terroir and during Muscat grapes fermentation unveiled by multi-omic analysis 多组学分析揭示了真菌群落在马斯喀特葡萄发酵过程中的作用

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-03 DOI: 10.1016/j.foodres.2026.118577

Paola Di Gianvito , Vania Sáez , Maria Dimopoulou , Christina Papandreou , Nicola Francesca , Urska Vrhovsek , Kalliopi Rantsiou , Luca Cocolin , Panagiotis Arapitsas , Vasileios Englezos

{"title":"The role of mycobiome in terroir and during Muscat grapes fermentation unveiled by multi-omic analysis","authors":"Paola Di Gianvito , Vania Sáez , Maria Dimopoulou , Christina Papandreou , Nicola Francesca , Urska Vrhovsek , Kalliopi Rantsiou , Luca Cocolin , Panagiotis Arapitsas , Vasileios Englezos","doi":"10.1016/j.foodres.2026.118577","DOIUrl":"10.1016/j.foodres.2026.118577","url":null,"abstract":"<div><div>The wine microbiome is a key determinant in shaping wine terroir. To date, a comprehensive understanding of how microbial signatures influence wine metabolic profile remains poorly understood. To address this, in the present study an integrated shotgun metagenomics and untargeted metabolomic approach was employed to investigate the wine metabolome and connect the composition and functions of microbiomes involved in wine fermentation of Muscat grapes harvested in Italy and Greece. Beta diversity highlighted the dissimilarity between Italian and Greek fungal terroirs. A marked reduction in diversity during fermentation underscored the dominance of the inoculated <em>Saccharomyces cerevisiae</em> starter culture. The LEfSe analysis revealed an enrichment of <em>Torulaspora delbrueckii</em> in Greek samples, while <em>Kluyveromyces marxianus</em> and <em>lactis</em> were more abundant in Italian samples. Functional analysis revealed geographic differences in nucleotide, fatty acids and lysine metabolisms. Significant shifts were observed in energy, carbohydrate, and amino acid metabolisms, reflecting terroir-specific microbial activity. The metabolomics data highlighted regional differences in oligosaccharides, glycosylated phenolics, peptide and amino acid turnover, and central redox metabolites, suggesting divergent microbial responses and metabolic trajectories shaped by terroir and fermentation conditions. Obtained results highlight the effectiveness of this multi-omics approach in identifying product-specific fungal communities and wine metabolite signatures, providing new tools that could be used to ensure wine authenticity and quality control.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118577"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trans-2-hexenal-loaded gelatin/dialdehyde starch/nanocellulose cushioning aerogel: synergistic postharvest preservation of Chinese bayberry with 1-MCP 载反式2-己烯醛明胶/双醛淀粉/纳米纤维素缓冲气凝胶：杨梅采后与1-MCP的协同保鲜

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-06 DOI: 10.1016/j.foodres.2026.118612

Jiarui Tong , Xiangrong Zhu , Xiumei Chen , Nengguo Tao

{"title":"Trans-2-hexenal-loaded gelatin/dialdehyde starch/nanocellulose cushioning aerogel: synergistic postharvest preservation of Chinese bayberry with 1-MCP","authors":"Jiarui Tong , Xiangrong Zhu , Xiumei Chen , Nengguo Tao","doi":"10.1016/j.foodres.2026.118612","DOIUrl":"10.1016/j.foodres.2026.118612","url":null,"abstract":"<div><div>Chinese bayberry is a highly fragile and perishable fruit that requires protective and functional packaging to maintain its postharvest quality. In this study, a novel bio-based aerogel was developed using a gelatin/dialdehyde starch matrix reinforced with cellulose nanofibrils (CNF) via Schiff-base crosslinking and freeze-drying. The as-prepared aerogel exhibited superior compressibility, elasticity, and biodegradability. This aerogel was further functionalized by loading <em>trans</em>-2-hexenal (E2H) and combined with 1-methylcyclopropene (1-MCP) treatment, thereby constructing a postharvest preservation system for Chinese bayberry with the triple functionality of ethylene inhibition, antifungal activity, and cushioning performance. The optimal aerogel formulation (30% CNF content) demonstrated robust mechanical performance and sustained E2H release behavior, which followed first-order kinetics. In vitro and in vivo assays confirmed its significant inhibitory effect against <em>Penicillium citrinum</em>, the primary postharvest pathogen of bayberry. Storage experiments at 4 °C revealed that the synergistic effect of E2H-loaded aerogel pads and 1-MCP treatment effectively reduced decay, preserved firmness and nutritional quality, and extended the shelf life of bayberries to 18 d, significantly surpassing the control group which lost commercial value after 8 d. Furthermore, the aerogel completely degraded in soil within two weeks, confirming its potential as an eco-friendly packaging material. This work, integrating both protective and active preservation functionalities, provides a sustainable and efficient packaging approach for fragile fruit.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118612"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel spectral correction method for eliminating shell interference and improving NIR detection accuracy of internal defect in Torreya grandis nuts 一种消除壳干扰提高香榧内部缺陷近红外检测精度的新光谱校正方法

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-08 DOI: 10.1016/j.foodres.2026.118629

Jiajun Zan , Binyan Hou , Yuan Du , Yu Hu , Lili Son , Jiasheng Wu , Tong Sun

{"title":"A novel spectral correction method for eliminating shell interference and improving NIR detection accuracy of internal defect in Torreya grandis nuts","authors":"Jiajun Zan , Binyan Hou , Yuan Du , Yu Hu , Lili Son , Jiasheng Wu , Tong Sun","doi":"10.1016/j.foodres.2026.118629","DOIUrl":"10.1016/j.foodres.2026.118629","url":null,"abstract":"<div><div>Spectral interference from the shell significantly affects the detection of internal defect of in-shell Torreya grandis nuts, reducing detection accuracy. To address this issue, a near-infrared spectral correction method combining a fully connected neural network (FNN) with Gaussian filtering (GS) was developed to eliminate interference from the shell spectra and improve the accuracy of black kernel defect detection. The correction performance of three methods, including direct standardization (DS), piecewise direct standardization (PDS), and the proposed FNN combined with GS, was compared. And detection models were constructed using RF, SVM, XGBoost, and LightGBM. Results shows that DS and PDS provide limited correction, leading to no significant improvement and even a decline in model performance. In contrast, the FNN combined with GS achieves more effective correction and significantly enhances classification accuracy. On the prediction set, RF and SVM models both reach 100% in accuracy, sensitivity, and specificity. XGBoost and LightGBM achieve 95.83% accuracy, with 100% specificity and 91.67% sensitivity. Compared to models developed using uncorrected raw spectral, RF and SVM models show improvements of 16.67% and 19.44% in sensitivity, and 8.33% and 9.72% in accuracy, respectively. Compared to models developed using kernel spectra, RF and SVM models surpass them in both accuracy and sensitivity. The proposed correction method effectively removes shell-related spectral interference, enhances defect-related spectral features, and enables high-precision, non-destructive detection of black kernel defect. This approach offers valuable reference for internal quality assessment in other nut varieties using NIRS.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118629"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scavenging multiple reactive carbonyl species simultaneously by mangiferin and its aglycone norathyriol in vitro and in vivo 芒果苷及其苷元去甲三醇在体外和体内同时清除多种活性羰基物质

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-08 DOI: 10.1016/j.foodres.2026.118639

Ruoying Du , Xiaoyun Jiang , Yichen Wang , Jin Wang , Bo Si , Chun Chang , Yonglin Lu , Lishuang Lv

{"title":"Scavenging multiple reactive carbonyl species simultaneously by mangiferin and its aglycone norathyriol in vitro and in vivo","authors":"Ruoying Du , Xiaoyun Jiang , Yichen Wang , Jin Wang , Bo Si , Chun Chang , Yonglin Lu , Lishuang Lv","doi":"10.1016/j.foodres.2026.118639","DOIUrl":"10.1016/j.foodres.2026.118639","url":null,"abstract":"<div><div>Reactive carbonyl species (RCS), including acrolein (ACR), methylglyoxal (MGO), and glyoxal (GO), are highly reactive compounds that accumulate in the body and contribute to chronic diseases. We investigated the reaction rate and kinetics of three types of RCS with mangiferin (MGF), and its metabolite, norathyriol (NTR), and clarified the pathways through the formation of RCS-adducts <em>in vitro</em>. Using UHPLC-QQQ-MS/MS, we then detected RCS-adducts of MGF and NTR (including MGF-ACR, MGF-2ACR, MGF-MGO, MGF-GO, NTR-ACR, NTR-MGO, NTR-2MGO, and NTR-GO) in urine and fecal samples following gavage administration of MGF (100/200 mg/kg bw with or without 500 mg/kg bw MGO/GO) in mice. Synthesized standards for NTR-ACR and NTR-MGO (whose structures were elucidated by NMR) were used for quantitative analysis. Our results demonstrated that both MGF and NTR formed RCS-adducts in a dose-dependent manner (3.1- to 2.5-fold increase). The total amount of RCS adducts in urine was significantly higher than that in feces (2.6- to 9.1-fold increase), with NTR-adducts being more abundant than MGF-adducts (1.5- to 5.2-fold increase). These findings were further validated in human trials, where participants consumed <em>Anemarrhena asphodeloides</em> root tea. The RCS-adducts were excreted through urine, reaching peak excretion levels within 4–6 h for MGF-related RCS-adducts, and 6–8 h for NTR-related RCS-adducts post-consumption. This study highlights MGF's potential as an effective RCS eliminator, with its metabolite, NTR, playing a key role in capturing RCS <em>in vivo</em>. Our findings suggest that MGF and NTR, as novel RCS scavengers, reduce RCS levels in the body, including through dietary plants rich in MGF.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118639"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio-based sweet potato starch cryogels: Linking hydrogel rheological properties to cryogel structure–functionalities 生物基甘薯淀粉冷冻剂：将水凝胶流变特性与冷冻凝胶结构功能联系起来

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-05 DOI: 10.1016/j.foodres.2026.118587

Ana Clara Troya Raineri Fiocco , Rafael Contatori dos Santos , Ana Carla Kawazoe Sato , Orlando J. Rojas , Carolina Siqueira Franco Picone

{"title":"Bio-based sweet potato starch cryogels: Linking hydrogel rheological properties to cryogel structure–functionalities","authors":"Ana Clara Troya Raineri Fiocco , Rafael Contatori dos Santos , Ana Carla Kawazoe Sato , Orlando J. Rojas , Carolina Siqueira Franco Picone","doi":"10.1016/j.foodres.2026.118587","DOIUrl":"10.1016/j.foodres.2026.118587","url":null,"abstract":"<div><div>Starch-based cryogels provide a sustainable solution to environmental and industrial challenges due to their biodegradability and tunable properties. Although sweet potato starch is abundant and low-cost, it remains underutilized, representing an economically attractive and sustainable source. This study reports the development of starch-based cryogels using sweet potato as a novel starch source. The effect of starch concentration and gelatinization degree on hydrogel rheology was correlated with cryogel structural, mechanical, and thermal properties. Higher starch concentrations produced more elastic dispersions with lower gelation temperatures and enhanced molecular interactions, which improved structural integrity during drying, resulting in stronger and less deformable cryogels. Gelatinization times of 7 and 15 min resulted in denser networks with smaller and more continuous pores. DSC analysis confirmed rapid gelatinization of sweet potato starch (86% at 90 °C/15 min). Water absorption increased (up to 9.79 g/g) with starch concentration and gelatinization time, while oil absorption was higher at lower starch levels (19 g/g). Additionally, low thermal conductivity (0.035–0.037 W/m·K) confirmed the cryogel insulation capacity. The results demonstrate that sweet potato starch-based cryogels combine enhanced functionality with sustainability, providing an alternative to conventional materials. These improvements underscore their potential applications in food, nutraceutical, and packaging areas.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118587"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A synbiotic combination of arabinogalactan and Bacteroides thetaiotaomicron ameliorates ulcerative colitis in mice 阿拉伯半乳聚糖和拟杆菌的合成组合可改善小鼠溃疡性结肠炎

IF 8 1区农林科学

Food Research International Pub Date : 2026-04-30 Epub Date: 2026-02-07 DOI: 10.1016/j.foodres.2026.118617

Shanshan Zhang, Yonggan Sun, Yuhao Li, Chunhua Chen, Shaoping Nie

{"title":"A synbiotic combination of arabinogalactan and Bacteroides thetaiotaomicron ameliorates ulcerative colitis in mice","authors":"Shanshan Zhang, Yonggan Sun, Yuhao Li, Chunhua Chen, Shaoping Nie","doi":"10.1016/j.foodres.2026.118617","DOIUrl":"10.1016/j.foodres.2026.118617","url":null,"abstract":"<div><div>Inflammatory bowel disease (IBD) is a chronic disease associated with excessive inflammation and gut microbiota dysbiosis. Synbiotic intervention represents a novel management strategy for IBD. However, there remains a critical need to identify new synbiotic combinations and to elucidate their effects on microbial structure and metabolic profiles. This study investigated the therapeutic potential of a combination of arabinogalactan (AG) and <em>Bacteroides thetaiotaomicron</em> (BT) in a dextran sulfate sodium (DSS)-induced colitis mouse model. AG-BT treatment ameliorated colitis-associated phenotypes, reduced intestinal inflammation, and promoted the expression of intestinal barrier-related proteins. They modulated the gut microbiota composition by promoting the abundance of beneficial bacteria such as unclassified Lachnospiraceae and <em>Oscillospira</em>, while suppressing the abundance of potentially pathogenic bacteria such as <em>Streptococcus</em> and <em>Ruminococcus</em>. Notably, AG-BT reshaped the intestinal metabolic profile, enhancing the metabolic pathways of arginine and proline metabolism and arginine biosynthesis, and promoting arginine levels. Correlation analysis revealed associations between colitis-related parameters, microbiota, and metabolites. These findings highlight the potential of the AG-BT as a synbiotic candidate in managing IBD and improving gut health, and also offer new insights into the application of AG in the food and pharmaceutical industries.</div></div>","PeriodicalId":323,"journal":{"name":"Food Research International","volume":"230 ","pages":"Article 118617"},"PeriodicalIF":8.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0