{"title":"Subcellular localization prediction of eukaryotic proteins using functional domain frequency measure","authors":"H. Hsiao, J. Tsai, Shih-Hao Chen","doi":"10.1109/MMSE.2003.1254452","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254452","url":null,"abstract":"Biologically, the function of a protein is highly related to its subcellular localization. Accordingly, it is necessary to develop an automatic yet reliable method for protein subcellular localization prediction, especially when large-scale genome sequences are to be analyzed. Various methods have been proposed to perform the task. The results, however, are not satisfactory in terms of effectiveness and efficiency. The proposed functional domain frequency measure (FDFM) is considerably simple yet greatly effective for subcellular localization prediction in a supervised fashion. The experimental results demonstrate that the total accuracy for three separate datasets by the FDFM method can reach up to 89.4%, 93.5% and 89%, respectively.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130199546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A united approach to discover multimedia Web services","authors":"Q. Liang, S. Su, Haifei Li, Jen-Yao Chung","doi":"10.1109/MMSE.2003.1254423","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254423","url":null,"abstract":"Web services technology has been making steady progress since its initial emergence in the beginning of this century. Since multimedia data have become ubiquitous on the Internet, it is not surprising that multimedia Web services have been receiving attention by the Web services community. On the Web services platform, UDDI is the current de facto service discovery approach. However, researchers have noticed that the UDDI business model has not really achieved its designated goal. We have proposed an approach to complement UDDI with WSIL in the Web services discovery. The idea behind Unified Web Service Discovery (UWSD) is to use both the brokering-based approach and the trust-based approach in Web services discovery. Further, UWSD is designed for handling multimedia service discovery with specific QoS considerations. The services discovered by UWSD are separated into two groups. The first group contains a relatively limited number of services that are trustworthy and guaranteed. The second group contains a large number of services, but the content is not guaranteed to be trustworthy. A markup language is also designed to facilitate the discovery process. We believe that the UWSD approach can better meet the current demand of multimedia Web services discovery.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"2017 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126940739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simsearcher: a local similarity search engine for biological sequence databases","authors":"Tian-Haw Tsai, Suh-Yin Lee","doi":"10.1109/MMSE.2003.1254456","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254456","url":null,"abstract":"An efficient local similarity search engine is developed by exploiting some techniques of data mining. All frequent patterns in the database are retrieved and recorded in a one-time preprocessing process. Then a query sequence is checked to see whether any pattern from the preprocessing stage is matched to the query. Two regions coming from the query and a database sequence that both match a pattern form a possible seed for local similarity. Finally, we extend and score each such seed region pair to see whether there really exists local similarity with a score high enough for reporting. For computational efficiency, a novel clustering approach is proposed and integrated into the proposed system, which is based on the local similarity search engine - the DELPHI system proposed by IBM. Extensive experiments are demonstrated to show the performance of our system.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130345638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Deng, Taehyung Wang, P. Sheu, H. Maezawa, F. Tsunoda, A. Onoma
{"title":"DPSSEE: a distributed proactive semantic software engineering environment","authors":"D. Deng, Taehyung Wang, P. Sheu, H. Maezawa, F. Tsunoda, A. Onoma","doi":"10.1109/MMSE.2003.1254433","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254433","url":null,"abstract":"We present a distributed proactive semantic software engineering environment (DPSSEE) that incorporates logic rules into software development process to capture the semantics from all levels of the software life cycle. It introduces the syntax and semantics of the rule description language (RDL) employed by DPSSEE and two working scenarios that illustrate the use of proactive rules for workflow control and design consistency checking.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117158695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using functionally important sites to identify orthologous relations","authors":"Hsuan-Chao Chiu, Yuh-Jyh Hu","doi":"10.1109/MMSE.2003.1254451","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254451","url":null,"abstract":"Making accurate functional predictions for genes plays an important role in the era of proteomics. The most reliable functional information is extracted from orthologs in other species when annotating an unknown gene. Here a site-based approach is proposed to predict orthologous relations. The method first identifies important sites that confer specificity of paralogs in the multiple sequence alignment of homologous proteins. It then predicts orthologous relations for unannotated proteins based on the important sites found. When applied to the bacterial transcription factor PurR/LacI family and the protein kinase AGC group family, our method was able to identify, with few false positives, the important sites that agree with those obtained from biological experiments. We also tested it on the AGC group family, the /spl alpha/-proteasome family, the glycoprotein hormone family and the growth hormone family to demonstrate its ability to predict orthologs. Compared with other prediction methods based on phylogenetic analysis or hidden Markov models, our method not only has competitive prediction accuracy, but also provides valuable biological information of important sites associated with orthologs which can be further studied in biological experiments.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122299076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An intelligent agent-based biomedical literature mining system for cancer-related genes","authors":"Shih-Nung Chen, J. Tsai, Wei-Hao Chen","doi":"10.1109/MMSE.2003.1254453","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254453","url":null,"abstract":"Cancer has now become the major disease threatening people's health. That is why research on the factor causing cancer has become significant. Although biomedical researchers can obtain a lot of related biomedical literature through a search engine, they also have to face the problem of information overload as well. We propose an intelligent agent system regarding the data mining of biomedical literature, hoping to provide assistance. According to the type of cancer user enter, the system will automatically combine it with LOH (loss of heterozygosity) or CGH (comparative genomic hybridization), and then search for related biomedical literatures from the PubMed. And then the retrieved literatures will be categorized using the decision tree, with which the cancer-related genes can be mined at the same time. The method can help mine important information from biomedical literatures and thus helps users to gain quick and easy access to important information. Also, this method can be applied to other diseases.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"306 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123205980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Middleware support for coordination in distributed applications","authors":"C. Chiang, P. Tang","doi":"10.1109/MMSE.2003.1254436","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254436","url":null,"abstract":"The current state of the art of existing middleware technologies does not support the development of distributed applications that need processes to complete a task collaboratively. We extend current middleware technologies with multiparty interaction rather than design a new distributed programming language for application developers. An object adapter for coordination running as a component provides support for the coordinated applications by isolating, encapsulating, and managing a component's interactions outside the component. Dynamic interface binding was designed to allow an adapter to examine the signature of the requested services at runtime such as operation names, parameter orders, parameter types, and parameter sizes. The interfaces of interconnecting components are bound at runtime. In addition, the interface language mapping allows an interface in a specific programming language to be automatically generated from an IP (interacting processes)-like IDL (IP-IDL) interface. The use of IP-IDL for coordination simplifies the development of distributed applications for coordination.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128971769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multimedia software for elearning: an old topic seen in a new light","authors":"M. Mühlhäuser","doi":"10.1109/MMSE.2003.1254415","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254415","url":null,"abstract":"Based on a short revision of the history of elearning, an overview of current and upcoming concepts is given. The elearning categories introduced are used as a guideline to derive major challenges with respect to multimedia (elearning) software engineering, and may be used to devise a strategy for the introduction of sustainable elearning in organizations.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133432157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A content management system for adaptive learning environment","authors":"Norman W. Y. Shao, Stephen J. H. Yang, A. S. Sue","doi":"10.1109/MMSE.2003.1254443","DOIUrl":"https://doi.org/10.1109/MMSE.2003.1254443","url":null,"abstract":"More and more digital technologies are developing along with an incredible amount of information. No one can read or browse all the information, so worthy information needs to be organized, stored and managed during its life-cycle. In a school environment, there are assets to maintain to educate students. We propose a content management system with metadata technology in the school learning environment. We use a metadata technique to describe the content which is from creating, retrieving, rendering, and delivering phases. We describe the architecture and implementation details of the system with a simple example.","PeriodicalId":322357,"journal":{"name":"Fifth International Symposium on Multimedia Software Engineering, 2003. Proceedings.","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114537205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}